PubMed:32571880 / 1583-1846 JSONTXT

{"project":"LitCovid-OGER-BB","denotations":[{"id":"T37","span":{"begin":17,"end":25},"obj":"CHEBI:36357"},{"id":"T38","span":{"begin":17,"end":25},"obj":"CHEBI:36357"},{"id":"T39","span":{"begin":55,"end":63},"obj":"SP_10"},{"id":"T40","span":{"begin":136,"end":146},"obj":"SP_7"},{"id":"T41","span":{"begin":180,"end":190},"obj":"CHEBI:35222"},{"id":"T42","span":{"begin":180,"end":190},"obj":"CHEBI:35222"},{"id":"T43","span":{"begin":213,"end":222},"obj":"CHEBI:36357"},{"id":"T44","span":{"begin":213,"end":222},"obj":"CHEBI:36357"},{"id":"T45","span":{"begin":245,"end":253},"obj":"SP_7"}],"namespaces":[{"prefix":"NCBITaxon","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"}],"text":"Finally, a small molecule previously shown to bind the SARS-CoV pseudoknot and inhibit -1 PRF was similarly effective against -1 PRF in SARS-CoV-2, suggesting that such frameshift inhibitors may be promising lead compounds to combat the current COVID-19 pandemic."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T13","span":{"begin":55,"end":63},"obj":"Disease"},{"id":"T14","span":{"begin":136,"end":144},"obj":"Disease"},{"id":"T15","span":{"begin":245,"end":253},"obj":"Disease"}],"attributes":[{"id":"A13","pred":"mondo_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A14","pred":"mondo_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A15","pred":"mondo_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"Finally, a small molecule previously shown to bind the SARS-CoV pseudoknot and inhibit -1 PRF was similarly effective against -1 PRF in SARS-CoV-2, suggesting that such frameshift inhibitors may be promising lead compounds to combat the current COVID-19 pandemic."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T16","span":{"begin":9,"end":10},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"Finally, a small molecule previously shown to bind the SARS-CoV pseudoknot and inhibit -1 PRF was similarly effective against -1 PRF in SARS-CoV-2, suggesting that such frameshift inhibitors may be promising lead compounds to combat the current COVID-19 pandemic."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T3","span":{"begin":17,"end":25},"obj":"Chemical"},{"id":"T4","span":{"begin":180,"end":190},"obj":"Chemical"},{"id":"T5","span":{"begin":208,"end":222},"obj":"Chemical"}],"attributes":[{"id":"A3","pred":"chebi_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/CHEBI_25367"},{"id":"A4","pred":"chebi_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"},{"id":"A5","pred":"chebi_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/CHEBI_33585"}],"text":"Finally, a small molecule previously shown to bind the SARS-CoV pseudoknot and inhibit -1 PRF was similarly effective against -1 PRF in SARS-CoV-2, suggesting that such frameshift inhibitors may be promising lead compounds to combat the current COVID-19 pandemic."}

{"project":"LitCovid-PubTator","denotations":[{"id":"29","span":{"begin":55,"end":63},"obj":"Species"},{"id":"30","span":{"begin":136,"end":146},"obj":"Species"},{"id":"31","span":{"begin":245,"end":253},"obj":"Disease"}],"attributes":[{"id":"A29","pred":"tao:has_database_id","subj":"29","obj":"Tax:694009"},{"id":"A30","pred":"tao:has_database_id","subj":"30","obj":"Tax:2697049"},{"id":"A31","pred":"tao:has_database_id","subj":"31","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Finally, a small molecule previously shown to bind the SARS-CoV pseudoknot and inhibit -1 PRF was similarly effective against -1 PRF in SARS-CoV-2, suggesting that such frameshift inhibitors may be promising lead compounds to combat the current COVID-19 pandemic."}

{"project":"LitCovid-sentences","denotations":[{"id":"T11","span":{"begin":0,"end":263},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Finally, a small molecule previously shown to bind the SARS-CoV pseudoknot and inhibit -1 PRF was similarly effective against -1 PRF in SARS-CoV-2, suggesting that such frameshift inhibitors may be promising lead compounds to combat the current COVID-19 pandemic."}

{"project":"sentences","denotations":[{"id":"T11","span":{"begin":0,"end":263},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Finally, a small molecule previously shown to bind the SARS-CoV pseudoknot and inhibit -1 PRF was similarly effective against -1 PRF in SARS-CoV-2, suggesting that such frameshift inhibitors may be promising lead compounds to combat the current COVID-19 pandemic."}

{"project":"mondo_disease","denotations":[{"id":"T13","span":{"begin":55,"end":63},"obj":"Disease"},{"id":"T14","span":{"begin":136,"end":146},"obj":"Disease"},{"id":"T15","span":{"begin":245,"end":253},"obj":"Disease"}],"attributes":[{"id":"A13","pred":"mondo_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A14","pred":"mondo_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A15","pred":"mondo_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"Finally, a small molecule previously shown to bind the SARS-CoV pseudoknot and inhibit -1 PRF was similarly effective against -1 PRF in SARS-CoV-2, suggesting that such frameshift inhibitors may be promising lead compounds to combat the current COVID-19 pandemic."}

{"project":"NCBITAXON","denotations":[{"id":"T10","span":{"begin":55,"end":63},"obj":"OrganismTaxon"},{"id":"T11","span":{"begin":136,"end":144},"obj":"OrganismTaxon"}],"attributes":[{"id":"A10","pred":"db_id","subj":"T10","obj":"694009"},{"id":"A11","pred":"db_id","subj":"T11","obj":"694009"}],"text":"Finally, a small molecule previously shown to bind the SARS-CoV pseudoknot and inhibit -1 PRF was similarly effective against -1 PRF in SARS-CoV-2, suggesting that such frameshift inhibitors may be promising lead compounds to combat the current COVID-19 pandemic."}