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PubMed:32542212 JSONTXT

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LitCovid-OGER-BB

Id Subject Object Predicate Lexical cue
T1 6-13 CHEBI:24505 denotes heparin
T2 6-13 CHEBI:24505 denotes heparin
T3 14-23 CHEBI:36357 denotes molecules
T4 14-23 CHEBI:36357 denotes molecules
T5 50-61 NCBITaxon:11118 denotes coronavirus
T6 76-84 SP_7 denotes COVID-19
T7 199-203 CHEBI:23888 denotes drug
T8 199-203 CHEBI:23888 denotes drug
T9 321-335 CHEBI:52217 denotes pharmaceutical
T10 321-335 CHEBI:52217 denotes pharmaceutical
T11 407-414 CHEBI:24505 denotes heparin
T12 407-414 CHEBI:24505 denotes heparin
T13 457-468 NCBITaxon:11118 denotes coronavirus
T14 474-486 GO:0050817 denotes coagulopathy
T15 533-540 CHEBI:24505 denotes heparin
T16 533-540 CHEBI:24505 denotes heparin
T17 545-553 SP_7 denotes COVID-19
T18 566-575 GO:0043335 denotes unfolding
T19 616-623 CHEBI:24505 denotes heparin
T20 616-623 CHEBI:24505 denotes heparin
T21 629-638 CHEBI:36357 denotes molecules
T22 629-638 CHEBI:36357 denotes molecules
T23 691-738 SP_7 denotes severe acute respiratory syndrome coronavirus 2
T24 704-715 UBERON:0001004 denotes respiratory
T25 740-750 SP_7 denotes SARS-CoV-2
T26 844-851 CHEBI:24505 denotes heparin
T27 844-851 CHEBI:24505 denotes heparin
T28 880-890 SP_7 denotes SARS-CoV-2
T29 963-973 SP_7 denotes SARS-CoV-2
T30 1001-1008 CHEBI:24505 denotes heparin
T31 1001-1008 CHEBI:24505 denotes heparin
T32 1009-1018 CHEBI:36357 denotes molecules
T33 1009-1018 CHEBI:36357 denotes molecules

LitCovid_Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 6-13 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T2 6-13 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T3 407-414 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T4 407-414 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T5 533-540 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T6 533-540 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T7 616-623 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T8 616-623 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T9 844-851 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T10 844-851 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T11 1001-1008 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T12 1001-1008 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 6-13 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T2 407-414 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T3 533-540 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T4 616-623 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T5 844-851 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T6 1001-1008 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 34-44 Disease denotes COVID-2019 http://purl.obolibrary.org/obo/MONDO_0100096
T2 50-74 Disease denotes coronavirus disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T3 76-84 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T4 228-237 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T5 474-486 Disease denotes coagulopathy http://purl.obolibrary.org/obo/MONDO_0001531
T6 545-553 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T7 691-738 Disease denotes severe acute respiratory syndrome coronavirus 2 http://purl.obolibrary.org/obo/MONDO_0100096
T8 691-724 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T9 740-748 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T10 752-761 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T11 880-888 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T12 891-900 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T13 963-971 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T14 974-983 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 653-654 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T2 926-927 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T3 1045-1046 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 6-13 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T2 14-23 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T3 199-203 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T4 321-335 Chemical denotes pharmaceutical http://purl.obolibrary.org/obo/CHEBI_52217
T5 407-414 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T6 533-540 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T7 616-623 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T8 629-638 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T9 844-851 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T10 1001-1008 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T11 1009-1018 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 474-486 Phenotype denotes coagulopathy http://purl.obolibrary.org/obo/HP_0003256

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T1 0-45 Sentence denotes Using heparin molecules to manage COVID-2019.
T2 46-172 Sentence denotes The coronavirus disease 2019 (COVID-19) pandemic is becoming one of the largest global public health crises in modern history.
T3 173-345 Sentence denotes The race for an effective drug to prevent or treat the infection is the highest priority among health care providers, government officials, and the pharmaceutical industry.
T4 346-487 Sentence denotes Recent evidence reports that the use of low-molecular-weight heparin reduces mortality in patients with severe coronavirus with coagulopathy.
T5 488-762 Sentence denotes Although the full scope of the benefits from heparin for COVID-19 patients is unfolding, encouraging clinical data suggest that heparin-like molecules may represent a useful approach to treat or prevent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.
T6 763-901 Sentence denotes The intent of this article is to offer our opinions on the mechanism(s) by which heparin may attenuate the course of SARS-CoV-2 infection.
T7 902-1074 Sentence denotes Furthermore, we propose a novel strategy to treat or prevent SARS-CoV-2 infection using "designer" heparin molecules that are fabricated using a synthetic biology approach.