PubMed:32277065 / 341-349
Halting coronavirus polymerase.
The nucleotide analogue remdesivir is an investigational drug for the treatment of human coronavirus infection. Remdesivir is a phosphoramidate prodrug and is known to target viral RNA-dependent RNA polymerases. In this issue, Gordon et al. identify that remdesivir acts as a delayed RNA chain terminator for MERS-CoV polymerase complexes.
|
projects
Unselected (3) / annnotation (23) | Selected (0) / annnotation (0) | |
|
|
|