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Comment on "Organ-protective Effect of Angiotensin-converting Enzyme 2 and its Effect on the Prognosis of COVID-19". We read with great interest the article by Cheng H et al. The authors mentioned that angiotensin-converting enzyme 2 (ACE2) is protective against novel coronavirus disease 2019 (COVID-19). We would like to explain how cytosolic pH increases the COVID-19 infection by affecting the ACE2. In addition, we would like to mention that amiloride, which increases the cytosolic pH, can be used in the COVID-19 treatment. This article is protected by copyright. All rights reserved.

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