PubMed:32215956 JSONTXT

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{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/32215956","sourcedb":"PubMed","sourceid":"32215956","source_url":"https://www.ncbi.nlm.nih.gov/pubmed/32215956","text":"Covid-19 and the Digestive System.\nThe novel coronavirus disease (Covid-19) is currently causing a major pandemic. It is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a member of the Betacoronavirus genus that also includes the SARS-CoV and Middle East Respiratory Syndrome Coronavirus (MERS-CoV). While patients typically present with fever and a respiratory illness, some patients also report gastrointestinal symptoms such as diarrhoea, vomiting and abdominal pain. Studies have identified the SARS-CoV-2 RNA in stool specimens of infected patients, and its viral receptor angiotensin converting enzyme 2 (ACE2) was found to be highly expressed in gastrointestinal epithelial cells. These suggest that SARS-CoV-2 can actively infect and replicate in the gastrointestinal tract. 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