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coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia.\nBACKGROUND: In the recent outbreak of novel coronavirus infection in Wuhan, China, significantly abnormal coagulation parameters in severe novel coronavirus pneumonia (NCP) cases were a concern.\nOBJECTIVES: To describe the coagulation feature of patients with NCP.\nMETHODS: Conventional coagulation results and outcomes of 183 consecutive patients with confirmed NCP in Tongji hospital were retrospectively analyzed.\nRESULTS: The overall mortality was 11.5%, the non-survivors revealed significantly higher D-dimer and fibrin degradation product (FDP) levels, longer prothrombin time and activated partial thromboplastin time compared to survivors on admission (P \u003c .05); 71.4% of non-survivors and 0.6% survivors met the criteria of disseminated intravascular coagulation during their hospital stay.\nCONCLUSIONS: The present study shows that abnormal coagulation results, especially markedly elevated D-dimer and FDP are common in deaths with NCP."}

{"project":"LitCovid-ArguminSci","denotations":[{"id":"T1","span":{"begin":0,"end":112},"obj":"DRI_Outcome"},{"id":"T2","span":{"begin":113,"end":307},"obj":"DRI_Background"},{"id":"T3","span":{"begin":308,"end":377},"obj":"DRI_Challenge"},{"id":"T4","span":{"begin":378,"end":529},"obj":"DRI_Background"},{"id":"T5","span":{"begin":530,"end":913},"obj":"DRI_Outcome"},{"id":"T6","span":{"begin":914,"end":1061},"obj":"DRI_Background"}],"text":"Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia.\nBACKGROUND: In the recent outbreak of novel coronavirus infection in Wuhan, China, significantly abnormal coagulation parameters in severe novel coronavirus pneumonia (NCP) cases were a concern.\nOBJECTIVES: To describe the coagulation feature of patients with NCP.\nMETHODS: Conventional coagulation results and outcomes of 183 consecutive patients with confirmed NCP in Tongji hospital were retrospectively analyzed.\nRESULTS: The overall mortality was 11.5%, the non-survivors revealed significantly higher D-dimer and fibrin degradation product (FDP) levels, longer prothrombin time and activated partial thromboplastin time compared to survivors on admission (P \u003c .05); 71.4% of non-survivors and 0.6% survivors met the criteria of disseminated intravascular coagulation during their hospital stay.\nCONCLUSIONS: The present study shows that abnormal coagulation results, especially markedly elevated D-dimer and FDP are common in deaths with NCP."}

{"project":"LitCovid-OGER","denotations":[{"id":"T1","span":{"begin":632,"end":638},"obj":"CHEBI:5054"},{"id":"T1","span":{"begin":9,"end":20},"obj":"GO:0050817"},{"id":"T2","span":{"begin":219,"end":230},"obj":"GO:0050817"},{"id":"T3","span":{"begin":336,"end":347},"obj":"GO:0050817"},{"id":"T4","span":{"begin":400,"end":411},"obj":"GO:0050817"},{"id":"T5","span":{"begin":639,"end":650},"obj":"GO:0009056"},{"id":"T6","span":{"begin":874,"end":885},"obj":"GO:0050817"},{"id":"T7","span":{"begin":965,"end":976},"obj":"GO:0050817"},{"id":"T1","span":{"begin":622,"end":627},"obj":"GO:0046983"},{"id":"T2","span":{"begin":1017,"end":1022},"obj":"GO:0046983"},{"id":"T1","span":{"begin":660,"end":663},"obj":"PR:000022576;PR:000012077"},{"id":"T2","span":{"begin":719,"end":733},"obj":"PR:000001940"},{"id":"T3","span":{"begin":1027,"end":1030},"obj":"PR:000022576;PR:000012077"},{"id":"T1","span":{"begin":32,"end":35},"obj":"SO:0001853"},{"id":"T2","span":{"begin":1031,"end":1034},"obj":"SO:0001853"}],"namespaces":[{"prefix":"PR","uri":"http://purl.obolibrary.org/obo/PR_"},{"prefix":"UBERON","uri":"http://purl.obolibrary.org/obo/UBERON_"}],"text":"Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia.\nBACKGROUND: In the recent outbreak of novel coronavirus infection in Wuhan, China, significantly abnormal coagulation parameters in severe novel coronavirus pneumonia (NCP) cases were a concern.\nOBJECTIVES: To describe the coagulation feature of patients with NCP.\nMETHODS: Conventional coagulation results and outcomes of 183 consecutive patients with confirmed NCP in Tongji hospital were retrospectively analyzed.\nRESULTS: The overall mortality was 11.5%, the non-survivors revealed significantly higher D-dimer and fibrin degradation product (FDP) levels, longer prothrombin time and activated partial thromboplastin time compared to survivors on admission (P \u003c .05); 71.4% of non-survivors and 0.6% survivors met the criteria of disseminated intravascular coagulation during their hospital stay.\nCONCLUSIONS: The present study shows that abnormal coagulation results, especially markedly elevated D-dimer and FDP are common in deaths with NCP."}

{"project":"LitCovid-PubTatorCentral","denotations":[{"id":"T1","span":{"begin":0,"end":20},"obj":"Disease:MESH:D025861"},{"id":"T2","span":{"begin":70,"end":78},"obj":"Species:9606"},{"id":"T3","span":{"begin":90,"end":111},"obj":"Disease:MESH:D018352"},{"id":"T4","span":{"begin":157,"end":178},"obj":"Disease:MESH:D018352"},{"id":"T5","span":{"begin":210,"end":230},"obj":"Disease:MESH:D025861"},{"id":"T6","span":{"begin":258,"end":279},"obj":"Disease:MESH:D018352"},{"id":"T7","span":{"begin":359,"end":367},"obj":"Species:9606"},{"id":"T8","span":{"begin":452,"end":460},"obj":"Species:9606"},{"id":"T9","span":{"begin":860,"end":885},"obj":"Disease:MESH:D004211"},{"id":"T10","span":{"begin":956,"end":976},"obj":"Disease:MESH:D025861"}],"text":"Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia.\nBACKGROUND: In the recent outbreak of novel coronavirus infection in Wuhan, China, significantly abnormal coagulation parameters in severe novel coronavirus pneumonia (NCP) cases were a concern.\nOBJECTIVES: To describe the coagulation feature of patients with NCP.\nMETHODS: Conventional coagulation results and outcomes of 183 consecutive patients with confirmed NCP in Tongji hospital were retrospectively analyzed.\nRESULTS: The overall mortality was 11.5%, the non-survivors revealed significantly higher D-dimer and fibrin degradation product (FDP) levels, longer prothrombin time and activated partial thromboplastin time compared to survivors on admission (P \u003c .05); 71.4% of non-survivors and 0.6% survivors met the criteria of disseminated intravascular coagulation during their hospital stay.\nCONCLUSIONS: The present study shows that abnormal coagulation results, especially markedly elevated D-dimer and FDP are common in deaths with NCP."}

{"project":"LitCovid-sentences-v1","denotations":[{"id":"TextSentencer_T1","span":{"begin":0,"end":112},"obj":"Sentence"},{"id":"TextSentencer_T2","span":{"begin":113,"end":124},"obj":"Sentence"},{"id":"TextSentencer_T3","span":{"begin":125,"end":307},"obj":"Sentence"},{"id":"TextSentencer_T4","span":{"begin":308,"end":319},"obj":"Sentence"},{"id":"TextSentencer_T5","span":{"begin":320,"end":377},"obj":"Sentence"},{"id":"TextSentencer_T6","span":{"begin":378,"end":386},"obj":"Sentence"},{"id":"TextSentencer_T7","span":{"begin":387,"end":529},"obj":"Sentence"},{"id":"TextSentencer_T8","span":{"begin":530,"end":538},"obj":"Sentence"},{"id":"TextSentencer_T9","span":{"begin":539,"end":913},"obj":"Sentence"},{"id":"TextSentencer_T10","span":{"begin":914,"end":926},"obj":"Sentence"},{"id":"TextSentencer_T11","span":{"begin":927,"end":1061},"obj":"Sentence"}],"text":"Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia.\nBACKGROUND: In the recent outbreak of novel coronavirus infection in Wuhan, China, significantly abnormal coagulation parameters in severe novel coronavirus pneumonia (NCP) cases were a concern.\nOBJECTIVES: To describe the coagulation feature of patients with NCP.\nMETHODS: Conventional coagulation results and outcomes of 183 consecutive patients with confirmed NCP in Tongji hospital were retrospectively analyzed.\nRESULTS: The overall mortality was 11.5%, the non-survivors revealed significantly higher D-dimer and fibrin degradation product (FDP) levels, longer prothrombin time and activated partial thromboplastin time compared to survivors on admission (P \u003c .05); 71.4% of non-survivors and 0.6% survivors met the criteria of disseminated intravascular coagulation during their hospital stay.\nCONCLUSIONS: The present study shows that abnormal coagulation results, especially markedly elevated D-dimer and FDP are common in deaths with NCP."}

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coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia.\nBACKGROUND: In the recent outbreak of novel coronavirus infection in Wuhan, China, significantly abnormal coagulation parameters in severe novel coronavirus pneumonia (NCP) cases were a concern.\nOBJECTIVES: To describe the coagulation feature of patients with NCP.\nMETHODS: Conventional coagulation results and outcomes of 183 consecutive patients with confirmed NCP in Tongji hospital were retrospectively analyzed.\nRESULTS: The overall mortality was 11.5%, the non-survivors revealed significantly higher D-dimer and fibrin degradation product (FDP) levels, longer prothrombin time and activated partial thromboplastin time compared to survivors on admission (P \u003c .05); 71.4% of non-survivors and 0.6% survivors met the criteria of disseminated intravascular coagulation during their hospital stay.\nCONCLUSIONS: The present study shows that abnormal coagulation results, especially markedly elevated D-dimer and FDP are common in deaths with NCP."}

{"project":"LitCovid-PD-MONDO-v1","denotations":[{"id":"T1","span":{"begin":102,"end":111},"obj":"Disease"},{"id":"T2","span":{"begin":169,"end":178},"obj":"Disease"},{"id":"T3","span":{"begin":270,"end":279},"obj":"Disease"},{"id":"T4","span":{"begin":847,"end":885},"obj":"Disease"}],"attributes":[{"id":"A1","pred":"mondo_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"},{"id":"A2","pred":"mondo_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A3","pred":"mondo_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"},{"id":"A4","pred":"mondo_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/MONDO_0001243"}],"text":"Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia.\nBACKGROUND: In the recent outbreak of novel coronavirus infection in Wuhan, China, significantly abnormal coagulation parameters in severe novel coronavirus pneumonia (NCP) cases were a concern.\nOBJECTIVES: To describe the coagulation feature of patients with NCP.\nMETHODS: Conventional coagulation results and outcomes of 183 consecutive patients with confirmed NCP in Tongji hospital were retrospectively analyzed.\nRESULTS: The overall mortality was 11.5%, the non-survivors revealed significantly higher D-dimer and fibrin degradation product (FDP) levels, longer prothrombin time and activated partial thromboplastin time compared to survivors on admission (P \u003c .05); 71.4% of non-survivors and 0.6% survivors met the criteria of disseminated intravascular coagulation during their hospital stay.\nCONCLUSIONS: The present study shows that abnormal coagulation results, especially markedly elevated D-dimer and FDP are common in deaths with NCP."}

{"project":"LitCovid-PD-HP-v1","denotations":[{"id":"T1","span":{"begin":0,"end":20},"obj":"Phenotype"},{"id":"T2","span":{"begin":102,"end":111},"obj":"Phenotype"},{"id":"T3","span":{"begin":210,"end":230},"obj":"Phenotype"},{"id":"T4","span":{"begin":270,"end":279},"obj":"Phenotype"},{"id":"T5","span":{"begin":847,"end":885},"obj":"Phenotype"},{"id":"T6","span":{"begin":956,"end":976},"obj":"Phenotype"}],"attributes":[{"id":"A1","pred":"hp_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/HP_0001928"},{"id":"A2","pred":"hp_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"id":"A3","pred":"hp_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/HP_0001928"},{"id":"A4","pred":"hp_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"id":"A5","pred":"hp_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/HP_0005521"},{"id":"A6","pred":"hp_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/HP_0001928"}],"text":"Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia.\nBACKGROUND: In the recent outbreak of novel coronavirus infection in Wuhan, China, significantly abnormal coagulation parameters in severe novel coronavirus pneumonia (NCP) cases were a concern.\nOBJECTIVES: To describe the coagulation feature of patients with NCP.\nMETHODS: Conventional coagulation results and outcomes of 183 consecutive patients with confirmed NCP in Tongji hospital were retrospectively analyzed.\nRESULTS: The overall mortality was 11.5%, the non-survivors revealed significantly higher D-dimer and fibrin degradation product (FDP) levels, longer prothrombin time and activated partial thromboplastin time compared to survivors on admission (P \u003c .05); 71.4% of non-survivors and 0.6% survivors met the criteria of disseminated intravascular coagulation during their hospital stay.\nCONCLUSIONS: The present study shows that abnormal coagulation results, especially markedly elevated D-dimer and FDP are common in deaths with NCP."}

{"project":"LitCovid-OGER-BB","denotations":[{"id":"T1","span":{"begin":9,"end":20},"obj":"GO:0050817"},{"id":"T2","span":{"begin":90,"end":101},"obj":"NCBITaxon:11118"},{"id":"T3","span":{"begin":157,"end":168},"obj":"NCBITaxon:11118"},{"id":"T4","span":{"begin":219,"end":230},"obj":"GO:0050817"},{"id":"T5","span":{"begin":258,"end":269},"obj":"NCBITaxon:11118"},{"id":"T6","span":{"begin":336,"end":347},"obj":"GO:0050817"},{"id":"T7","span":{"begin":400,"end":411},"obj":"GO:0050817"},{"id":"T8","span":{"begin":632,"end":638},"obj":"CHEBI:5054"},{"id":"T9","span":{"begin":632,"end":638},"obj":"CHEBI:5054"},{"id":"T10","span":{"begin":860,"end":873},"obj":"GO:0035556"},{"id":"T11","span":{"begin":874,"end":885},"obj":"GO:0050817"},{"id":"T12","span":{"begin":965,"end":976},"obj":"GO:0050817"},{"id":"T13","span":{"begin":1045,"end":1051},"obj":"GO:0016265"}],"namespaces":[{"prefix":"NCBITaxon","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"}],"text":"Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia.\nBACKGROUND: In the recent outbreak of novel coronavirus infection in Wuhan, China, significantly abnormal coagulation parameters in severe novel coronavirus pneumonia (NCP) cases were a concern.\nOBJECTIVES: To describe the coagulation feature of patients with NCP.\nMETHODS: Conventional coagulation results and outcomes of 183 consecutive patients with confirmed NCP in Tongji hospital were retrospectively analyzed.\nRESULTS: The overall mortality was 11.5%, the non-survivors revealed significantly higher D-dimer and fibrin degradation product (FDP) levels, longer prothrombin time and activated partial thromboplastin time compared to survivors on admission (P \u003c .05); 71.4% of non-survivors and 0.6% survivors met the criteria of disseminated intravascular coagulation during their hospital stay.\nCONCLUSIONS: The present study shows that abnormal coagulation results, especially markedly elevated D-dimer and FDP are common in deaths with NCP."}

{"project":"LitCovid_AGAC","denotations":[{"id":"p112582s16","span":{"begin":620,"end":621},"obj":"MPA"}],"text":"Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia.\nBACKGROUND: In the recent outbreak of novel coronavirus infection in Wuhan, China, significantly abnormal coagulation parameters in severe novel coronavirus pneumonia (NCP) cases were a concern.\nOBJECTIVES: To describe the coagulation feature of patients with NCP.\nMETHODS: Conventional coagulation results and outcomes of 183 consecutive patients with confirmed NCP in Tongji hospital were retrospectively analyzed.\nRESULTS: The overall mortality was 11.5%, the non-survivors revealed significantly higher D-dimer and fibrin degradation product (FDP) levels, longer prothrombin time and activated partial thromboplastin time compared to survivors on admission (P \u003c .05); 71.4% of non-survivors and 0.6% survivors met the criteria of disseminated intravascular coagulation during their hospital stay.\nCONCLUSIONS: The present study shows that abnormal coagulation results, especially markedly elevated D-dimer and FDP are common in deaths with NCP."}