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PubMed:31908101 JSONTXT

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Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-84 Sentence denotes Granulomatous mural folliculitis in a dog treated with ciclosporin and methotrexate.
T2 85-96 Sentence denotes BACKGROUND:
T3 97-205 Sentence denotes Canine granulomatous mural folliculitis is a very rare cause of scarring alopecia with unknown pathogenesis.
T4 206-228 Sentence denotes HYPOTHESIS/OBJECTIVES:
T5 229-344 Sentence denotes To report a case of granulomatous mural folliculitis in a dog treated with ciclosporin (Cs) and methotrexate (MTX).
T6 345-352 Sentence denotes ANIMAL:
T7 353-449 Sentence denotes A 13-year-old spayed female Pyrenean shepherd dog with a one month history of scarring alopecia.
T8 450-470 Sentence denotes METHODS AND RESULTS:
T9 471-594 Sentence denotes Histopathological examination revealed a granulomatous and lymphocytic mural and necrotizing folliculitis and furunculosis.
T10 595-774 Sentence denotes Immunochemistry, using antibodies for CD3, CD204, CD206, IBA-1 and CD208, revealed that CD3+ lymphocytes were infiltrating the outer root sheath along with IBA-1+ or CD204+ cells.
T11 775-953 Sentence denotes Ciclosporin (5 mg/kg once daily) and MTX (0.25 mg/kg once weekly then 0.5 mg/kg once weekly) were initiated simultaneously, and Cs was stopped after stabilization of the lesions.
T12 954-1003 Sentence denotes The dog's skin disease was stable for six months.
T13 1004-1040 Sentence denotes CONCLUSIONS AND CLINICAL IMPORTANCE:
T14 1041-1180 Sentence denotes To the best of the authors' knowledge, this is the first report of the long-term management of a granulomatous mural folliculitis in a dog.
T15 1181-1246 Sentence denotes Ciclosporin and MTX appeared to be an effective treatment option.
T16 1247-1353 Sentence denotes Additional treated cases are needed to assess the effectiveness of MTX in canine immune-mediated diseases.
T1 0-84 Sentence denotes Granulomatous mural folliculitis in a dog treated with ciclosporin and methotrexate.
T2 85-96 Sentence denotes BACKGROUND:
T3 97-205 Sentence denotes Canine granulomatous mural folliculitis is a very rare cause of scarring alopecia with unknown pathogenesis.
T4 206-228 Sentence denotes HYPOTHESIS/OBJECTIVES:
T5 229-344 Sentence denotes To report a case of granulomatous mural folliculitis in a dog treated with ciclosporin (Cs) and methotrexate (MTX).
T6 345-352 Sentence denotes ANIMAL:
T7 353-449 Sentence denotes A 13-year-old spayed female Pyrenean shepherd dog with a one month history of scarring alopecia.
T8 450-470 Sentence denotes METHODS AND RESULTS:
T9 471-594 Sentence denotes Histopathological examination revealed a granulomatous and lymphocytic mural and necrotizing folliculitis and furunculosis.
T10 595-774 Sentence denotes Immunochemistry, using antibodies for CD3, CD204, CD206, IBA-1 and CD208, revealed that CD3+ lymphocytes were infiltrating the outer root sheath along with IBA-1+ or CD204+ cells.
T11 775-953 Sentence denotes Ciclosporin (5 mg/kg once daily) and MTX (0.25 mg/kg once weekly then 0.5 mg/kg once weekly) were initiated simultaneously, and Cs was stopped after stabilization of the lesions.
T12 954-1003 Sentence denotes The dog's skin disease was stable for six months.
T13 1004-1040 Sentence denotes CONCLUSIONS AND CLINICAL IMPORTANCE:
T14 1041-1180 Sentence denotes To the best of the authors' knowledge, this is the first report of the long-term management of a granulomatous mural folliculitis in a dog.
T15 1181-1246 Sentence denotes Ciclosporin and MTX appeared to be an effective treatment option.
T16 1247-1353 Sentence denotes Additional treated cases are needed to assess the effectiveness of MTX in canine immune-mediated diseases.