PubMed:31375147 JSONTXT

{"project":"PubMed_ArguminSci","denotations":[{"id":"T1","span":{"begin":100,"end":289},"obj":"DRI_Outcome"}],"text":"A statistical and biological response to an informatics appraisal of healthy aging gene signatures.\nJacob and Speed did not identify even a single example of a '150-gene-set' that was statistically significant at classifying Alzheimer's disease (AD) samples, or age in independent studies. We attempt to clarify the various misunderstandings, below."}

{"project":"Goldhamster2_Cellosaurus","denotations":[{"id":"T1","span":{"begin":0,"end":1},"obj":"CVCL_6479|Finite_cell_line|Mus musculus"},{"id":"T2","span":{"begin":41,"end":43},"obj":"CVCL_8754|Cancer_cell_line|Homo sapiens"},{"id":"T3","span":{"begin":41,"end":43},"obj":"CVCL_H241|Cancer_cell_line|Homo sapiens"},{"id":"T4","span":{"begin":138,"end":139},"obj":"CVCL_6479|Finite_cell_line|Mus musculus"},{"id":"T5","span":{"begin":158,"end":159},"obj":"CVCL_6479|Finite_cell_line|Mus musculus"},{"id":"T6","span":{"begin":170,"end":173},"obj":"CVCL_WY71|Spontaneously_immortalized_cell_line|Oncorhynchus keta"},{"id":"T7","span":{"begin":246,"end":248},"obj":"CVCL_M606|Cancer_cell_line|Homo sapiens"},{"id":"T8","span":{"begin":262,"end":265},"obj":"CVCL_Z433|Spontaneously_immortalized_cell_line|Anthonomus grandis"},{"id":"T9","span":{"begin":262,"end":265},"obj":"CVCL_Z658|Spontaneously_immortalized_cell_line|Anticarsia gemmatalis"},{"id":"T10","span":{"begin":290,"end":292},"obj":"CVCL_5M23|Cancer_cell_line|Mesocricetus auratus"}],"text":"A statistical and biological response to an informatics appraisal of healthy aging gene signatures.\nJacob and Speed did not identify even a single example of a '150-gene-set' that was statistically significant at classifying Alzheimer's disease (AD) samples, or age in independent studies. We attempt to clarify the various misunderstandings, below."}

{"project":"GoldHamster","denotations":[{"id":"T1","span":{"begin":77,"end":82},"obj":"GO:0007568"},{"id":"T2","span":{"begin":83,"end":87},"obj":"SO:0000704"},{"id":"T3","span":{"begin":165,"end":169},"obj":"SO:0000704"},{"id":"T8","span":{"begin":225,"end":244},"obj":"D000544"},{"id":"T9","span":{"begin":225,"end":244},"obj":"D000544"}],"text":"A statistical and biological response to an informatics appraisal of healthy aging gene signatures.\nJacob and Speed did not identify even a single example of a '150-gene-set' that was statistically significant at classifying Alzheimer's disease (AD) samples, or age in independent studies. We attempt to clarify the various misunderstandings, below."}