PubMed:31262895 JSONTXT

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In addition, autophagy with specific molecules beclin-1 and microtubule-associated protein 1A/1B-light chain 3 (LC3)-II/LC3-I (ratio \u003e1). Later at 10 h, autophagy-associated proteins were observed, and at 24 h, only survival proteins nuclear factor kappa-light-chain-enhancer of activated B-cells (NF-κB), and extracellular signal-regulated kinases (ERK)2/ERK1\u003e1 were found. Another relevant finding was the presence of caspase-10 throughout the study, especially in cells treated with CasIIgly and CasIIIEa.\nCONCLUSION: These relationships indicate a possible mechanism of action of Casiopeínas on neuroblastoma.","tracks":[{"project":"PubMed_Structured_Abstracts","denotations":[{"id":"T1","span":{"begin":98,"end":358},"obj":"BACKGROUND"},{"id":"T2","span":{"begin":382,"end":549},"obj":"METHODS"},{"id":"T3","span":{"begin":559,"end":1222},"obj":"RESULTS"},{"id":"T4","span":{"begin":1235,"end":1327},"obj":"CONCLUSIONS"}],"attributes":[{"subj":"T1","pred":"source","obj":"PubMed_Structured_Abstracts"},{"subj":"T2","pred":"source","obj":"PubMed_Structured_Abstracts"},{"subj":"T3","pred":"source","obj":"PubMed_Structured_Abstracts"},{"subj":"T4","pred":"source","obj":"PubMed_Structured_Abstracts"}]},{"project":"Goldhamster2_Cellosaurus","denotations":[{"id":"T1","span":{"begin":31,"end":38},"obj":"CVCL_1125|Cancer_cell_line|Homo 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