PubMed:31145890
Annnotations
GoldHamster
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T2 | 0-8 | SO:0000276 | denotes | MicroRNA |
T1 | 0-8 | D035683 | denotes | MicroRNA |
T3 | 22-40 | GO:0008283 | denotes | cell proliferation |
T4 | 27-40 | UBERON:2000098 | denotes | proliferation |
T5 | 45-55 | D009362 | denotes | metastasis |
T6 | 45-55 | D009362 | denotes | metastasis |
T7 | 59-66 | UBERON:0018707 | denotes | bladder |
T8 | 59-66 | UBERON:0001255 | denotes | bladder |
T9 | 59-73 | D001749 | denotes | bladder cancer |
T10 | 59-73 | D001749 | denotes | bladder cancer |
T11 | 10-19 | GO:0023052 | denotes | 21 inhibi |
T13 | 166-174 | SO:0000276 | denotes | microRNA |
T12 | 166-174 | D035683 | denotes | microRNA |
T14 | 180-183 | PR:000010459 | denotes | miR |
T15 | 180-183 | PR:Q9HAP2 | denotes | miR |
T16 | 180-183 | PR:Q9DBD2 | denotes | miR |
T17 | 180-183 | P13087 | denotes | miR |
T18 | 180-183 | D3ZDI6 | denotes | miR |
T19 | 180-183 | Q93105 | denotes | miR |
T20 | 180-183 | PR:Q5T0T0 | denotes | miR |
T21 | 180-183 | Q8BM54 | denotes | miR |
T22 | 180-183 | Q8WY64 | denotes | miR |
T23 | 180-183 | PR:000010844 | denotes | miR |
T24 | 180-183 | PR:Q2VPU4 | denotes | miR |
T25 | 180-183 | PR:000010182 | denotes | miR |
T26 | 180-183 | PR:Q6TEM9 | denotes | miR |
T27 | 235-242 | D009369 | denotes | cancers |
T28 | 235-242 | D009369 | denotes | cancers |
T29 | 265-268 | PR:000010459 | denotes | miR |
T30 | 265-268 | PR:Q9HAP2 | denotes | miR |
T31 | 265-268 | PR:Q9DBD2 | denotes | miR |
T32 | 265-268 | P13087 | denotes | miR |
T33 | 265-268 | D3ZDI6 | denotes | miR |
T34 | 265-268 | Q93105 | denotes | miR |
T35 | 265-268 | PR:Q5T0T0 | denotes | miR |
T36 | 265-268 | Q8BM54 | denotes | miR |
T37 | 265-268 | Q8WY64 | denotes | miR |
T38 | 265-268 | PR:000010844 | denotes | miR |
T39 | 265-268 | PR:Q2VPU4 | denotes | miR |
T40 | 265-268 | PR:000010182 | denotes | miR |
T41 | 265-268 | PR:Q6TEM9 | denotes | miR |
T42 | 276-283 | UBERON:0018707 | denotes | bladder |
T43 | 276-283 | UBERON:0001255 | denotes | bladder |
T44 | 276-290 | D001749 | denotes | bladder cancer |
T45 | 276-290 | D001749 | denotes | bladder cancer |
T46 | 292-295 | UBERON:2005000 | denotes | BCa |
T47 | 364-383 | CHEBI:24432 | denotes | biological function |
T48 | 412-415 | PR:000010459 | denotes | miR |
T49 | 412-415 | PR:Q9HAP2 | denotes | miR |
T50 | 412-415 | PR:Q9DBD2 | denotes | miR |
T51 | 412-415 | P13087 | denotes | miR |
T52 | 412-415 | D3ZDI6 | denotes | miR |
T53 | 412-415 | Q93105 | denotes | miR |
T54 | 412-415 | PR:Q5T0T0 | denotes | miR |
T55 | 412-415 | Q8BM54 | denotes | miR |
T56 | 412-415 | Q8WY64 | denotes | miR |
T57 | 412-415 | PR:000010844 | denotes | miR |
T58 | 412-415 | PR:Q2VPU4 | denotes | miR |
T59 | 412-415 | PR:000010182 | denotes | miR |
T60 | 412-415 | PR:Q6TEM9 | denotes | miR |
T61 | 423-426 | UBERON:2005000 | denotes | BCa |
T62 | 456-459 | PR:000010459 | denotes | miR |
T63 | 456-459 | PR:Q9HAP2 | denotes | miR |
T64 | 456-459 | PR:Q9DBD2 | denotes | miR |
T65 | 456-459 | P13087 | denotes | miR |
T66 | 456-459 | D3ZDI6 | denotes | miR |
T67 | 456-459 | Q93105 | denotes | miR |
T68 | 456-459 | PR:Q5T0T0 | denotes | miR |
T69 | 456-459 | Q8BM54 | denotes | miR |
T70 | 456-459 | Q8WY64 | denotes | miR |
T71 | 456-459 | PR:000010844 | denotes | miR |
T72 | 456-459 | PR:Q2VPU4 | denotes | miR |
T73 | 456-459 | PR:000010182 | denotes | miR |
T74 | 456-459 | PR:Q6TEM9 | denotes | miR |
T75 | 496-499 | UBERON:2005000 | denotes | BCa |
T76 | 557-560 | UBERON:2005000 | denotes | BCa |
T77 | 600-615 | CL:0000731 | denotes | urothelial cell |
T78 | 653-656 | PR:000010459 | denotes | miR |
T79 | 653-656 | PR:Q9HAP2 | denotes | miR |
T80 | 653-656 | PR:Q9DBD2 | denotes | miR |
T81 | 653-656 | P13087 | denotes | miR |
T82 | 653-656 | D3ZDI6 | denotes | miR |
T83 | 653-656 | Q93105 | denotes | miR |
T84 | 653-656 | PR:Q5T0T0 | denotes | miR |
T85 | 653-656 | Q8BM54 | denotes | miR |
T86 | 653-656 | Q8WY64 | denotes | miR |
T87 | 653-656 | PR:000010844 | denotes | miR |
T88 | 653-656 | PR:Q2VPU4 | denotes | miR |
T89 | 653-656 | PR:000010182 | denotes | miR |
T90 | 653-656 | PR:Q6TEM9 | denotes | miR |
T91 | 712-715 | UBERON:2005000 | denotes | BCa |
T92 | 765-768 | PR:000010459 | denotes | miR |
T93 | 765-768 | PR:Q9HAP2 | denotes | miR |
T94 | 765-768 | PR:Q9DBD2 | denotes | miR |
T95 | 765-768 | P13087 | denotes | miR |
T96 | 765-768 | D3ZDI6 | denotes | miR |
T97 | 765-768 | Q93105 | denotes | miR |
T98 | 765-768 | PR:Q5T0T0 | denotes | miR |
T99 | 765-768 | Q8BM54 | denotes | miR |
T100 | 765-768 | Q8WY64 | denotes | miR |
T101 | 765-768 | PR:000010844 | denotes | miR |
T102 | 765-768 | PR:Q2VPU4 | denotes | miR |
T103 | 765-768 | PR:000010182 | denotes | miR |
T104 | 765-768 | PR:Q6TEM9 | denotes | miR |
T105 | 787-800 | UBERON:2000098 | denotes | proliferation |
T106 | 805-815 | D009362 | denotes | metastasis |
T107 | 805-815 | D009362 | denotes | metastasis |
T108 | 819-822 | UBERON:2005000 | denotes | BCa |
T109 | 844-854 | P13129 | denotes | luciferase |
T110 | 844-854 | Q27757 | denotes | luciferase |
T111 | 844-854 | P08659 | denotes | luciferase |
T112 | 844-854 | Q01158 | denotes | luciferase |
T114 | 844-854 | Q26304 | denotes | luciferase |
T113 | 844-854 | D008156 | denotes | luciferase |
T115 | 873-876 | PR:000010459 | denotes | miR |
T116 | 873-876 | PR:Q9HAP2 | denotes | miR |
T117 | 873-876 | PR:Q9DBD2 | denotes | miR |
T118 | 873-876 | P13087 | denotes | miR |
T119 | 873-876 | D3ZDI6 | denotes | miR |
T120 | 873-876 | Q93105 | denotes | miR |
T121 | 873-876 | PR:Q5T0T0 | denotes | miR |
T122 | 873-876 | Q8BM54 | denotes | miR |
T123 | 873-876 | Q8WY64 | denotes | miR |
T124 | 873-876 | PR:000010844 | denotes | miR |
T125 | 873-876 | PR:Q2VPU4 | denotes | miR |
T126 | 873-876 | PR:000010182 | denotes | miR |
T127 | 873-876 | PR:Q6TEM9 | denotes | miR |
T128 | 903-909 | D020413 | denotes | 3' UTR |
T129 | 906-909 | SO:0000203 | denotes | UTR |
T130 | 906-909 | SO:0001622 | denotes | UTR |
T135 | 913-919 | PR:000016653 | denotes | TRIM29 |
T136 | 913-919 | PR:Q14134 | denotes | TRIM29 |
T137 | 913-919 | PR:Q8R2Q0 | denotes | TRIM29 |
T138 | 957-960 | UBERON:2005000 | denotes | BCa |
T139 | 1008-1011 | PR:000010459 | denotes | miR |
T140 | 1008-1011 | PR:Q9HAP2 | denotes | miR |
T141 | 1008-1011 | PR:Q9DBD2 | denotes | miR |
T142 | 1008-1011 | P13087 | denotes | miR |
T143 | 1008-1011 | D3ZDI6 | denotes | miR |
T144 | 1008-1011 | Q93105 | denotes | miR |
T145 | 1008-1011 | PR:Q5T0T0 | denotes | miR |
T146 | 1008-1011 | Q8BM54 | denotes | miR |
T147 | 1008-1011 | Q8WY64 | denotes | miR |
T148 | 1008-1011 | PR:000010844 | denotes | miR |
T149 | 1008-1011 | PR:Q2VPU4 | denotes | miR |
T150 | 1008-1011 | PR:000010182 | denotes | miR |
T151 | 1008-1011 | PR:Q6TEM9 | denotes | miR |
T152 | 1062-1065 | PR:000010459 | denotes | miR |
T153 | 1062-1065 | PR:Q9HAP2 | denotes | miR |
T154 | 1062-1065 | PR:Q9DBD2 | denotes | miR |
T155 | 1062-1065 | P13087 | denotes | miR |
T156 | 1062-1065 | D3ZDI6 | denotes | miR |
T157 | 1062-1065 | Q93105 | denotes | miR |
T158 | 1062-1065 | PR:Q5T0T0 | denotes | miR |
T159 | 1062-1065 | Q8BM54 | denotes | miR |
T160 | 1062-1065 | Q8WY64 | denotes | miR |
T161 | 1062-1065 | PR:000010844 | denotes | miR |
T162 | 1062-1065 | PR:Q2VPU4 | denotes | miR |
T163 | 1062-1065 | PR:000010182 | denotes | miR |
T164 | 1062-1065 | PR:Q6TEM9 | denotes | miR |
T165 | 1084-1097 | UBERON:2000098 | denotes | proliferation |
T166 | 1102-1112 | D009362 | denotes | metastasis |
T167 | 1102-1112 | D009362 | denotes | metastasis |
T168 | 1116-1119 | UBERON:2005000 | denotes | BCa |
T170 | 1144-1161 | GO:0007165 | denotes | signaling pathway |
T171 | 1154-1161 | CHEBI:34922 | denotes | pathway |
T176 | 1175-1181 | PR:000016653 | denotes | TRIM29 |
T177 | 1175-1181 | PR:Q14134 | denotes | TRIM29 |
T178 | 1175-1181 | PR:Q8R2Q0 | denotes | TRIM29 |
T179 | 1212-1215 | PR:000010459 | denotes | miR |
T180 | 1212-1215 | PR:Q9HAP2 | denotes | miR |
T181 | 1212-1215 | PR:Q9DBD2 | denotes | miR |
T182 | 1212-1215 | P13087 | denotes | miR |
T183 | 1212-1215 | D3ZDI6 | denotes | miR |
T184 | 1212-1215 | Q93105 | denotes | miR |
T185 | 1212-1215 | PR:Q5T0T0 | denotes | miR |
T186 | 1212-1215 | Q8BM54 | denotes | miR |
T187 | 1212-1215 | Q8WY64 | denotes | miR |
T188 | 1212-1215 | PR:000010844 | denotes | miR |
T189 | 1212-1215 | PR:Q2VPU4 | denotes | miR |
T190 | 1212-1215 | PR:000010182 | denotes | miR |
T191 | 1212-1215 | PR:Q6TEM9 | denotes | miR |
T196 | 1220-1226 | PR:000016653 | denotes | TRIM29 |
T197 | 1220-1226 | PR:Q14134 | denotes | TRIM29 |
T198 | 1220-1226 | PR:Q8R2Q0 | denotes | TRIM29 |
T199 | 1227-1231 | UBERON:0001093 | denotes | axis |
T200 | 1245-1258 | UBERON:2000098 | denotes | proliferation |
T201 | 1263-1273 | D009362 | denotes | metastasis |
T202 | 1263-1273 | D009362 | denotes | metastasis |
T203 | 1277-1280 | UBERON:2005000 | denotes | BCa |
T205 | 1305-1322 | GO:0007165 | denotes | signaling pathway |
T206 | 1315-1322 | CHEBI:34922 | denotes | pathway |
T207 | 1378-1381 | UBERON:2005000 | denotes | BCa |
PubMed_ArguminSci
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 114-243 | DRI_Background | denotes | Increasing evidence has shown that dysregulation of microRNA-621 (miR-621) is demonstrated to be associated with several cancers. |
T2 | 244-313 | DRI_Background | denotes | However, the role of miR-621 in bladder cancer (BCa) remains unclear. |
T3 | 314-427 | DRI_Approach | denotes | Herein, we aimed to study the expression pattern, biological function, and molecular mechanism of miR-621 in BCa. |
T4 | 428-621 | DRI_Outcome | denotes | First, we demonstrated that miR-621 was frequently downregulated in BCa tissues and cell lines compared with the adjacent normal BCa tissues and non-cancerous immortalized urothelial cell line. |
T5 | 622-725 | DRI_Outcome | denotes | In addition, the expression of miR-621 was negatively correlated with overall survival of BCa patients. |
T6 | 726-829 | DRI_Background | denotes | Functional experiments suggessted that miR-621 inhibited the proliferation and metastasis of BCa cells. |
T7 | 830-1027 | DRI_Background | denotes | Notably, dual-luciferase assay showed that miR-621 directly targeted the 3' UTR of TRIM29, which was frequently upregulated in BCa tissues and displayed inverse correlation with miR-621 expression. |
T8 | 1028-1182 | DRI_Outcome | denotes | Furthermore, we demonstrated that miR-621 inhibited the proliferation and metastasis of BCa cells via Wnt/β-catenin signaling pathway by targeting TRIM29. |
T9 | 1183-1405 | DRI_Outcome | denotes | Our study suggested that the miR-621/TRIM29 axis inhibits the proliferation and metastasis of BCa cells via Wnt/β-catenin signaling pathway and may have potential applications for development of BCa diagnosis or treatment. |
Goldhamster2_Cellosaurus
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 67-73 | CVCL_E025|Induced_pluripotent_stem_cell|Homo sapiens | denotes | cancer |
T2 | 134-137 | CVCL_6758|Undefined_cell_line_type|Cricetulus griseus | denotes | has |
T3 | 134-137 | CVCL_E689|Transformed_cell_line|Homo sapiens | denotes | has |
T4 | 235-242 | CVCL_E025|Induced_pluripotent_stem_cell|Homo sapiens | denotes | cancers |
T5 | 284-290 | CVCL_E025|Induced_pluripotent_stem_cell|Homo sapiens | denotes | cancer |
T6 | 322-324 | CVCL_5M23|Cancer_cell_line|Mesocricetus auratus | denotes | we |
T7 | 435-437 | CVCL_5M23|Cancer_cell_line|Mesocricetus auratus | denotes | we |
T8 | 577-586 | CVCL_E025|Induced_pluripotent_stem_cell|Homo sapiens | denotes | cancerous |
T9 | 1041-1043 | CVCL_5M23|Cancer_cell_line|Mesocricetus auratus | denotes | we |
T10 | 1327-1330 | CVCL_E773|Transformed_cell_line|Homo sapiens | denotes | may |