PubMed:31129139 / 1587-1849 JSON TXT

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Id	Subject	Object	Predicate	Lexical cue
T4	0-262	CONCLUSIONS	denotes	Our results suggested that HO could alleviate APAP-induced liver damage through reducing the generation of APAP-protein adducts, which might be mediated by inhibiting the activity of CYP 2E1 and CYP2A1 as well as enhancing the generation of GSH via NRF2 pathway.

Id	Subject	Object	Predicate	Lexical cue
T13	27-29	CVCL_M698\|Cancer_cell_line\|Homo sapiens	denotes	HO
T14	171-179	CVCL_C410\|Hybridoma\|Mus musculus	denotes	activity

Id	Subject	Object	Predicate	Lexical cue
T240	46-50	D000082	denotes	APAP
T241	46-50	D000082	denotes	APAP
T242	46-50	CHEBI:46195	denotes	APAP
T243	59-64	UBERON:0002107	denotes	liver
T244	107-111	D000082	denotes	APAP
T245	107-111	D000082	denotes	APAP
T246	107-111	CHEBI:46195	denotes	APAP
T251	112-119	SO:0000104	denotes	protein
T250	112-119	PR:000000001	denotes	protein
T248	112-119	CHEBI:36080	denotes	protein
T249	112-119	CHEBI:11122	denotes	protein
T247	112-119	GO:0003675	denotes	protein
T264	183-190	PR:P05182	denotes	CYP 2E1
T265	183-190	PR:000006122	denotes	CYP 2E1
T267	183-190	PR:Q05421	denotes	CYP 2E1
T268	183-190	PR:P05181	denotes	CYP 2E1
T266	183-190	D019392	denotes	CYP 2E1
T277	195-200	C029009	denotes	CYP2A
T278	195-201	PR:P11711	denotes	CYP2A1
T279	198-201	CVCL_XG57	denotes	2A1
T280	198-201	CVCL_1930	denotes	2A1
T282	241-244	CHEBI:16856	denotes	GSH
T281	241-244	C563177	denotes	GSH
T286	249-253	PR:Q60795	denotes	NRF2
T287	249-253	PR:O54968	denotes	NRF2
T288	249-253	PR:000011170	denotes	NRF2
T289	249-253	Q16236	denotes	NRF2
T290	249-253	PR:Q16236	denotes	NRF2
T291	254-261	CHEBI:34922	denotes	pathway