PubMed:30836660 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/30836660","sourcedb":"PubMed","sourceid":"30836660","source_url":"https://www.ncbi.nlm.nih.gov/pubmed/30836660","text":"Salidroside Ameliorates Renal Interstitial Fibrosis by Inhibiting the TLR4/NF-κB and MAPK Signaling Pathways.\nSalidroside (Sal) is an active ingredient that is isolated from Rhodiola rosea, which has been reported to have anti-inflammatory activities and a renal protective effect. However, the role of Sal on renal fibrosis has not yet been elucidated. Here, the purpose of the current study is to test the protective effects of Sal against renal interstitial fibrosis (RIF), and to explore the underlying mechanisms using both in vivo and in vitro models. In this study, we establish the unilateral ureteric obstruction (UUO) or folic acid (FA)-induced mice renal interstitial fibrosis in vivo and the transforming growth factor (TGF)-β1-stimulated human proximal tubular epithelial cell (HK-2) model in vitro. The levels of kidney functional parameters and inflammatory cytokines in serum are examined. The degree of renal damage and fibrosis is determined by histological assessment. Immunohistochemistry and western blotting are used to determine the mechanisms of Sal against RIF. Our results show that treatment with Sal can ameliorate tubular injury and deposition of the extracellular matrix (ECM) components (including collagen Ш and collagen I). Furthermore, Sal administration significantly suppresses epithelial-mesenchymal transition (EMT), as evidenced by a decreased expression of α-SMA, vimentin, TGF-β1, snail, slug, and a largely restored expression of E-cadherin. Additionally, Sal also reduces the levels of serum biochemical markers (serum creatinine, Scr; blood urea nitrogen, BUN; and uric acid, UA) and decreases the release of inflammatory cytokines (IL-1β, IL-6, TNF-α). Further study revealed that the effect of Sal on renal interstitial fibrosis is associated with the lower expression of TLR4, p-IκBα, p-NF-κB and mitogen-activated protein kinases (MAPK), both in vivo and in vitro. In conclusion, Sal treatment improves kidney function, ameliorates the deposition of the ECM components and relieves the protein levels of EMT markers in mouse kidneys and HK-2 cells. Furthermore, Sal treatment significantly decreases the release of inflammatory cytokines and inhibits the TLR4/NF-κB and MAPK signaling pathways. Collectively, these results suggest that the administration of Sal could be a novel therapeutic strategy in treating renal fibrosis.","tracks":[{"project":"Inflammaging","denotations":[{"id":"T1","span":{"begin":0,"end":109},"obj":"Sentence"},{"id":"T2","span":{"begin":110,"end":281},"obj":"Sentence"},{"id":"T3","span":{"begin":282,"end":353},"obj":"Sentence"},{"id":"T4","span":{"begin":354,"end":557},"obj":"Sentence"},{"id":"T5","span":{"begin":558,"end":812},"obj":"Sentence"},{"id":"T6","span":{"begin":813,"end":905},"obj":"Sentence"},{"id":"T7","span":{"begin":906,"end":987},"obj":"Sentence"},{"id":"T8","span":{"begin":988,"end":1086},"obj":"Sentence"},{"id":"T9","span":{"begin":1087,"end":1256},"obj":"Sentence"},{"id":"T10","span":{"begin":1257,"end":1483},"obj":"Sentence"},{"id":"T11","span":{"begin":1484,"end":1697},"obj":"Sentence"},{"id":"T12","span":{"begin":1698,"end":1912},"obj":"Sentence"},{"id":"T13","span":{"begin":1913,"end":2096},"obj":"Sentence"},{"id":"T14","span":{"begin":2097,"end":2242},"obj":"Sentence"},{"id":"T15","span":{"begin":2243,"end":2375},"obj":"Sentence"},{"id":"T1","span":{"begin":0,"end":109},"obj":"Sentence"},{"id":"T2","span":{"begin":110,"end":281},"obj":"Sentence"},{"id":"T3","span":{"begin":282,"end":353},"obj":"Sentence"},{"id":"T4","span":{"begin":354,"end":557},"obj":"Sentence"},{"id":"T5","span":{"begin":558,"end":812},"obj":"Sentence"},{"id":"T6","span":{"begin":813,"end":905},"obj":"Sentence"},{"id":"T7","span":{"begin":906,"end":987},"obj":"Sentence"},{"id":"T8","span":{"begin":988,"end":1086},"obj":"Sentence"},{"id":"T9","span":{"begin":1087,"end":1256},"obj":"Sentence"},{"id":"T10","span":{"begin":1257,"end":1483},"obj":"Sentence"},{"id":"T11","span":{"begin":1484,"end":1697},"obj":"Sentence"},{"id":"T12","span":{"begin":1698,"end":1912},"obj":"Sentence"},{"id":"T13","span":{"begin":1913,"end":2096},"obj":"Sentence"},{"id":"T14","span":{"begin":2097,"end":2242},"obj":"Sentence"},{"id":"T15","span":{"begin":2243,"end":2375},"obj":"Sentence"}],"attributes":[{"subj":"T1","pred":"source","obj":"Inflammaging"},{"subj":"T2","pred":"source","obj":"Inflammaging"},{"subj":"T3","pred":"source","obj":"Inflammaging"},{"subj":"T4","pred":"source","obj":"Inflammaging"},{"subj":"T5","pred":"source","obj":"Inflammaging"},{"subj":"T6","pred":"source","obj":"Inflammaging"},{"subj":"T7","pred":"source","obj":"Inflammaging"},{"subj":"T8","pred":"source","obj":"Inflammaging"},{"subj":"T9","pred":"source","obj":"Inflammaging"},{"subj":"T10","pred":"source","obj":"Inflammaging"},{"subj":"T11","pred":"source","obj":"Inflammaging"},{"subj":"T12","pred":"source","obj":"Inflammaging"},{"subj":"T13","pred":"source","obj":"Inflammaging"},{"subj":"T14","pred":"source","obj":"Inflammaging"},{"subj":"T15","pred":"source","obj":"Inflammaging"},{"subj":"T1","pred":"source","obj":"Inflammaging"},{"subj":"T2","pred":"source","obj":"Inflammaging"},{"subj":"T3","pred":"source","obj":"Inflammaging"},{"subj":"T4","pred":"source","obj":"Inflammaging"},{"subj":"T5","pred":"source","obj":"Inflammaging"},{"subj":"T6","pred":"source","obj":"Inflammaging"},{"subj":"T7","pred":"source","obj":"Inflammaging"},{"subj":"T8","pred":"source","obj":"Inflammaging"},{"subj":"T9","pred":"source","obj":"Inflammaging"},{"subj":"T10","pred":"source","obj":"Inflammaging"},{"subj":"T11","pred":"source","obj":"Inflammaging"},{"subj":"T12","pred":"source","obj":"Inflammaging"},{"subj":"T13","pred":"source","obj":"Inflammaging"},{"subj":"T14","pred":"source","obj":"Inflammaging"},{"subj":"T15","pred":"source","obj":"Inflammaging"}]},{"project":"LitCoin-entities-OrganismTaxon-PD","denotations":[{"id":"T1","span":{"begin":174,"end":188},"obj":"OrganismTaxon"},{"id":"T2","span":{"begin":655,"end":659},"obj":"OrganismTaxon"},{"id":"T4","span":{"begin":751,"end":756},"obj":"OrganismTaxon"},{"id":"T5","span":{"begin":2067,"end":2072},"obj":"OrganismTaxon"}],"attributes":[{"id":"A1","pred":"db_id","subj":"T1","obj":"NCBItxid:203015"},{"id":"A2","pred":"db_id","subj":"T2","obj":"NCBItxid:10095"},{"id":"A3","pred":"db_id","subj":"T2","obj":"NCBItxid:10088"},{"id":"A4","pred":"db_id","subj":"T4","obj":"NCBItxid:9606"},{"id":"A5","pred":"db_id","subj":"T5","obj":"NCBItxid:10090"},{"id":"A6","pred":"db_id","subj":"T5","obj":"NCBItxid:10088"},{"subj":"T1","pred":"source","obj":"LitCoin-entities-OrganismTaxon-PD"},{"subj":"T2","pred":"source","obj":"LitCoin-entities-OrganismTaxon-PD"},{"subj":"T4","pred":"source","obj":"LitCoin-entities-OrganismTaxon-PD"},{"subj":"T5","pred":"source","obj":"LitCoin-entities-OrganismTaxon-PD"}]},{"project":"LitCoin-sentences","denotations":[{"id":"T1","span":{"begin":0,"end":109},"obj":"Sentence"},{"id":"T2","span":{"begin":110,"end":281},"obj":"Sentence"},{"id":"T3","span":{"begin":282,"end":353},"obj":"Sentence"},{"id":"T4","span":{"begin":354,"end":557},"obj":"Sentence"},{"id":"T5","span":{"begin":558,"end":812},"obj":"Sentence"},{"id":"T6","span":{"begin":813,"end":905},"obj":"Sentence"},{"id":"T7","span":{"begin":906,"end":987},"obj":"Sentence"},{"id":"T8","span":{"begin":988,"end":1086},"obj":"Sentence"},{"id":"T9","span":{"begin":1087,"end":1256},"obj":"Sentence"},{"id":"T10","span":{"begin":1257,"end":1483},"obj":"Sentence"},{"id":"T11","span":{"begin":1484,"end":1697},"obj":"Sentence"},{"id":"T12","span":{"begin":1698,"end":1912},"obj":"Sentence"},{"id":"T13","span":{"begin":1913,"end":2096},"obj":"Sentence"},{"id":"T14","span":{"begin":2097,"end":2242},"obj":"Sentence"},{"id":"T15","span":{"begin":2243,"end":2375},"obj":"Sentence"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCoin-sentences"},{"subj":"T2","pred":"source","obj":"LitCoin-sentences"},{"subj":"T3","pred":"source","obj":"LitCoin-sentences"},{"subj":"T4","pred":"source","obj":"LitCoin-sentences"},{"subj":"T5","pred":"source","obj":"LitCoin-sentences"},{"subj":"T6","pred":"source","obj":"LitCoin-sentences"},{"subj":"T7","pred":"source","obj":"LitCoin-sentences"},{"subj":"T8","pred":"source","obj":"LitCoin-sentences"},{"subj":"T9","pred":"source","obj":"LitCoin-sentences"},{"subj":"T10","pred":"source","obj":"LitCoin-sentences"},{"subj":"T11","pred":"source","obj":"LitCoin-sentences"},{"subj":"T12","pred":"source","obj":"LitCoin-sentences"},{"subj":"T13","pred":"source","obj":"LitCoin-sentences"},{"subj":"T14","pred":"source","obj":"LitCoin-sentences"},{"subj":"T15","pred":"source","obj":"LitCoin-sentences"}]},{"project":"LitCoin-entities","denotations":[{"id":"13570","span":{"begin":0,"end":11},"obj":"ChemicalEntity"},{"id":"13571","span":{"begin":24,"end":51},"obj":"DiseaseOrPhenotypicFeature"},{"id":"13572","span":{"begin":70,"end":74},"obj":"GeneOrGeneProduct"},{"id":"13573","span":{"begin":75,"end":80},"obj":"GeneOrGeneProduct"},{"id":"13574","span":{"begin":85,"end":89},"obj":"GeneOrGeneProduct"},{"id":"13575","span":{"begin":110,"end":121},"obj":"ChemicalEntity"},{"id":"13576","span":{"begin":123,"end":126},"obj":"ChemicalEntity"},{"id":"13577","span":{"begin":174,"end":188},"obj":"OrganismTaxon"},{"id":"13578","span":{"begin":227,"end":239},"obj":"DiseaseOrPhenotypicFeature"},{"id":"13579","span":{"begin":303,"end":306},"obj":"ChemicalEntity"},{"id":"13580","span":{"begin":310,"end":324},"obj":"DiseaseOrPhenotypicFeature"},{"id":"13581","span":{"begin":430,"end":433},"obj":"ChemicalEntity"},{"id":"13582","span":{"begin":442,"end":469},"obj":"DiseaseOrPhenotypicFeature"},{"id":"13583","span":{"begin":471,"end":474},"obj":"DiseaseOrPhenotypicFeature"},{"id":"13584","span":{"begin":590,"end":621},"obj":"DiseaseOrPhenotypicFeature"},{"id":"13585","span":{"begin":623,"end":626},"obj":"DiseaseOrPhenotypicFeature"},{"id":"13586","span":{"begin":631,"end":641},"obj":"ChemicalEntity"},{"id":"13587","span":{"begin":643,"end":645},"obj":"ChemicalEntity"},{"id":"13588","span":{"begin":655,"end":659},"obj":"OrganismTaxon"},{"id":"13589","span":{"begin":660,"end":687},"obj":"DiseaseOrPhenotypicFeature"},{"id":"13590","span":{"begin":704,"end":739},"obj":"GeneOrGeneProduct"},{"id":"13591","span":{"begin":751,"end":756},"obj":"OrganismTaxon"},{"id":"13592","span":{"begin":791,"end":795},"obj":"CellLine"},{"id":"13593","span":{"begin":860,"end":872},"obj":"DiseaseOrPhenotypicFeature"},{"id":"13594","span":{"begin":920,"end":932},"obj":"DiseaseOrPhenotypicFeature"},{"id":"13595","span":{"begin":937,"end":945},"obj":"DiseaseOrPhenotypicFeature"},{"id":"13596","span":{"begin":1070,"end":1073},"obj":"ChemicalEntity"},{"id":"13597","span":{"begin":1082,"end":1085},"obj":"DiseaseOrPhenotypicFeature"},{"id":"13598","span":{"begin":1124,"end":1127},"obj":"ChemicalEntity"},{"id":"13599","span":{"begin":1143,"end":1157},"obj":"DiseaseOrPhenotypicFeature"},{"id":"13600","span":{"begin":1229,"end":1239},"obj":"GeneOrGeneProduct"},{"id":"13601","span":{"begin":1244,"end":1254},"obj":"GeneOrGeneProduct"},{"id":"13602","span":{"begin":1270,"end":1273},"obj":"ChemicalEntity"},{"id":"13603","span":{"begin":1397,"end":1402},"obj":"GeneOrGeneProduct"},{"id":"13604","span":{"begin":1404,"end":1412},"obj":"GeneOrGeneProduct"},{"id":"13605","span":{"begin":1414,"end":1420},"obj":"GeneOrGeneProduct"},{"id":"13606","span":{"begin":1422,"end":1427},"obj":"GeneOrGeneProduct"},{"id":"13607","span":{"begin":1429,"end":1433},"obj":"GeneOrGeneProduct"},{"id":"13608","span":{"begin":1472,"end":1482},"obj":"GeneOrGeneProduct"},{"id":"13609","span":{"begin":1498,"end":1501},"obj":"ChemicalEntity"},{"id":"13610","span":{"begin":1562,"end":1572},"obj":"ChemicalEntity"},{"id":"13611","span":{"begin":1585,"end":1589},"obj":"ChemicalEntity"},{"id":"13612","span":{"begin":1590,"end":1598},"obj":"ChemicalEntity"},{"id":"13613","span":{"begin":1609,"end":1618},"obj":"ChemicalEntity"},{"id":"13614","span":{"begin":1620,"end":1622},"obj":"ChemicalEntity"},{"id":"13615","span":{"begin":1653,"end":1665},"obj":"DiseaseOrPhenotypicFeature"},{"id":"13616","span":{"begin":1677,"end":1682},"obj":"GeneOrGeneProduct"},{"id":"13617","span":{"begin":1684,"end":1688},"obj":"GeneOrGeneProduct"},{"id":"13618","span":{"begin":1690,"end":1695},"obj":"GeneOrGeneProduct"},{"id":"13619","span":{"begin":1740,"end":1743},"obj":"ChemicalEntity"},{"id":"13620","span":{"begin":1747,"end":1774},"obj":"DiseaseOrPhenotypicFeature"},{"id":"13621","span":{"begin":1818,"end":1822},"obj":"GeneOrGeneProduct"},{"id":"13622","span":{"begin":1826,"end":1830},"obj":"GeneOrGeneProduct"},{"id":"13623","span":{"begin":1834,"end":1839},"obj":"GeneOrGeneProduct"},{"id":"13624","span":{"begin":1844,"end":1877},"obj":"GeneOrGeneProduct"},{"id":"13625","span":{"begin":1879,"end":1883},"obj":"GeneOrGeneProduct"},{"id":"13626","span":{"begin":1928,"end":1931},"obj":"ChemicalEntity"},{"id":"13627","span":{"begin":2067,"end":2072},"obj":"OrganismTaxon"},{"id":"13628","span":{"begin":2085,"end":2089},"obj":"CellLine"},{"id":"13629","span":{"begin":2110,"end":2113},"obj":"ChemicalEntity"},{"id":"13630","span":{"begin":2163,"end":2175},"obj":"DiseaseOrPhenotypicFeature"},{"id":"13631","span":{"begin":2203,"end":2207},"obj":"GeneOrGeneProduct"},{"id":"13632","span":{"begin":2208,"end":2213},"obj":"GeneOrGeneProduct"},{"id":"13633","span":{"begin":2218,"end":2222},"obj":"GeneOrGeneProduct"},{"id":"13634","span":{"begin":2306,"end":2309},"obj":"ChemicalEntity"},{"id":"13635","span":{"begin":2360,"end":2374},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A80","pred":"db_id","subj":"13628","obj":"NCBITaxon:9606"},{"id":"A22","pred":"db_id","subj":"13588","obj":"NCBITaxon:10090"},{"id":"A26","pred":"db_id","subj":"13592","obj":"NCBITaxon:9606"},{"id":"A85","pred":"db_id","subj":"13632","obj":"NCBIGene:18033"},{"id":"A86","pred":"db_id","subj":"13632","obj":"NCBIGene:4790"},{"id":"A11","pred":"db_id","subj":"13577","obj":"NCBITaxon:203015"},{"id":"A23","pred":"db_id","subj":"13589","obj":"MESH:D007674"},{"id":"A90","pred":"db_id","subj":"13635","obj":"MESH:D007674"},{"id":"A41","pred":"db_id","subj":"13603","obj":"NCBIGene:11475"},{"id":"A42","pred":"db_id","subj":"13603","obj":"NCBIGene:59"},{"id":"A64","pred":"db_id","subj":"13618","obj":"NCBIGene:21926"},{"id":"A65","pred":"db_id","subj":"13618","obj":"NCBIGene:7124"},{"id":"A10","pred":"db_id","subj":"13576","obj":"MESH:C009172"},{"id":"A13","pred":"db_id","subj":"13579","obj":"MESH:C009172"},{"id":"A5","pred":"db_id","subj":"13573","obj":"NCBIGene:18033"},{"id":"A6","pred":"db_id","subj":"13573","obj":"NCBIGene:4790"},{"id":"A18","pred":"db_id","subj":"13584","obj":"MESH:D014517"},{"id":"A72","pred":"db_id","subj":"13623","obj":"NCBIGene:18033"},{"id":"A73","pred":"db_id","subj":"13623","obj":"NCBIGene:4790"},{"id":"A67","pred":"db_id","subj":"13620","obj":"MESH:D007674"},{"id":"A87","pred":"db_id","subj":"13633","obj":"NCBIGene:26413"},{"id":"A88","pred":"db_id","subj":"13633","obj":"NCBIGene:5594"},{"id":"A53","pred":"db_id","subj":"13609","obj":"MESH:C009172"},{"id":"A60","pred":"db_id","subj":"13616","obj":"NCBIGene:16176"},{"id":"A61","pred":"db_id","subj":"13616","obj":"NCBIGene:3553"},{"id":"A78","pred":"db_id","subj":"13626","obj":"MESH:C009172"},{"id":"A7","pred":"db_id","subj":"13574","obj":"NCBIGene:26413"},{"id":"A8","pred":"db_id","subj":"13574","obj":"NCBIGene:5594"},{"id":"A24","pred":"db_id","subj":"13590","obj":"NCBIGene:21803"},{"id":"A89","pred":"db_id","subj":"13634","obj":"MESH:C009172"},{"id":"A25","pred":"db_id","subj":"13591","obj":"NCBITaxon:9606"},{"id":"A28","pred":"db_id","subj":"13594","obj":"MESH:D007674"},{"id":"A3","pred":"db_id","subj":"13572","obj":"NCBIGene:21898"},{"id":"A4","pred":"db_id","subj":"13572","obj":"NCBIGene:7099"},{"id":"A9","pred":"db_id","subj":"13575","obj":"MESH:C009172"},{"id":"A17","pred":"db_id","subj":"13583","obj":"MESH:D007674"},{"id":"A16","pred":"db_id","subj":"13582","obj":"MESH:D007674"},{"id":"A68","pred":"db_id","subj":"13621","obj":"NCBIGene:21898"},{"id":"A69","pred":"db_id","subj":"13621","obj":"NCBIGene:7099"},{"id":"A66","pred":"db_id","subj":"13619","obj":"MESH:C009172"},{"id":"A32","pred":"db_id","subj":"13598","obj":"MESH:C009172"},{"id":"A55","pred":"db_id","subj":"13611","obj":"MESH:D014508"},{"id":"A12","pred":"db_id","subj":"13578","obj":"MESH:D007249"},{"id":"A54","pred":"db_id","subj":"13610","obj":"MESH:D003404"},{"id":"A30","pred":"db_id","subj":"13596","obj":"MESH:C009172"},{"id":"A81","pred":"db_id","subj":"13629","obj":"MESH:C009172"},{"id":"A36","pred":"db_id","subj":"13601","obj":"NCBIGene:1277"},{"id":"A37","pred":"db_id","subj":"13601","obj":"NCBIGene:1278"},{"id":"A38","pred":"db_id","subj":"13601","obj":"NCBIGene:12842"},{"id":"A39","pred":"db_id","subj":"13601","obj":"NCBIGene:12843"},{"id":"A82","pred":"db_id","subj":"13630","obj":"MESH:D007249"},{"id":"A33","pred":"db_id","subj":"13599","obj":"MESH:D007674"},{"id":"A74","pred":"db_id","subj":"13624","obj":"NCBIGene:26413"},{"id":"A75","pred":"db_id","subj":"13624","obj":"NCBIGene:5594"},{"id":"A58","pred":"db_id","subj":"13614","obj":"MESH:D014527"},{"id":"A59","pred":"db_id","subj":"13615","obj":"MESH:D007249"},{"id":"A1","pred":"db_id","subj":"13570","obj":"MESH:C009172"},{"id":"A43","pred":"db_id","subj":"13604","obj":"NCBIGene:22352"},{"id":"A44","pred":"db_id","subj":"13604","obj":"NCBIGene:7431"},{"id":"A47","pred":"db_id","subj":"13606","obj":"NCBIGene:20613"},{"id":"A48","pred":"db_id","subj":"13606","obj":"NCBIGene:6615"},{"id":"A45","pred":"db_id","subj":"13605","obj":"NCBIGene:21803"},{"id":"A46","pred":"db_id","subj":"13605","obj":"NCBIGene:7040"},{"id":"A2","pred":"db_id","subj":"13571","obj":"MESH:D007674"},{"id":"A15","pred":"db_id","subj":"13581","obj":"MESH:C009172"},{"id":"A19","pred":"db_id","subj":"13585","obj":"MESH:D014517"},{"id":"A20","pred":"db_id","subj":"13586","obj":"MESH:D005492"},{"id":"A40","pred":"db_id","subj":"13602","obj":"MESH:C009172"},{"id":"A57","pred":"db_id","subj":"13613","obj":"MESH:D014527"},{"id":"A29","pred":"db_id","subj":"13595","obj":"MESH:D005355"},{"id":"A83","pred":"db_id","subj":"13631","obj":"NCBIGene:21898"},{"id":"A84","pred":"db_id","subj":"13631","obj":"NCBIGene:7099"},{"id":"A79","pred":"db_id","subj":"13627","obj":"NCBITaxon:10090"},{"id":"A56","pred":"db_id","subj":"13612","obj":"MESH:D009584"},{"id":"A14","pred":"db_id","subj":"13580","obj":"MESH:D007674"},{"id":"A49","pred":"db_id","subj":"13607","obj":"NCBIGene:20583"},{"id":"A50","pred":"db_id","subj":"13607","obj":"NCBIGene:6591"},{"id":"A70","pred":"db_id","subj":"13622","obj":"NCBIGene:18035"},{"id":"A71","pred":"db_id","subj":"13622","obj":"NCBIGene:4792"},{"id":"A34","pred":"db_id","subj":"13600","obj":"NCBIGene:1281"},{"id":"A35","pred":"db_id","subj":"13600","obj":"NCBIGene:12825"},{"id":"A62","pred":"db_id","subj":"13617","obj":"NCBIGene:16193"},{"id":"A63","pred":"db_id","subj":"13617","obj":"NCBIGene:3569"},{"id":"A31","pred":"db_id","subj":"13597","obj":"MESH:D007674"},{"id":"A76","pred":"db_id","subj":"13625","obj":"NCBIGene:26413"},{"id":"A77","pred":"db_id","subj":"13625","obj":"NCBIGene:5594"},{"id":"A27","pred":"db_id","subj":"13593","obj":"MESH:D007249"},{"id":"A21","pred":"db_id","subj":"13587","obj":"MESH:D005492"},{"id":"A51","pred":"db_id","subj":"13608","obj":"NCBIGene:12550"},{"id":"A52","pred":"db_id","subj":"13608","obj":"NCBIGene:999"},{"subj":"13570","pred":"source","obj":"LitCoin-entities"},{"subj":"13571","pred":"source","obj":"LitCoin-entities"},{"subj":"13572","pred":"source","obj":"LitCoin-entities"},{"subj":"13573","pred":"source","obj":"LitCoin-entities"},{"subj":"13574","pred":"source","obj":"LitCoin-entities"},{"subj":"13575","pred":"source","obj":"LitCoin-entities"},{"subj":"13576","pred":"source","obj":"LitCoin-entities"},{"subj":"13577","pred":"source","obj":"LitCoin-entities"},{"subj":"13578","pred":"source","obj":"LitCoin-entities"},{"subj":"13579","pred":"source","obj":"LitCoin-entities"},{"subj":"13580","pred":"source","obj":"LitCoin-entities"},{"subj":"13581","pred":"source","obj":"LitCoin-entities"},{"subj":"13582","pred":"source","obj":"LitCoin-entities"},{"subj":"13583","pred":"source","obj":"LitCoin-entities"},{"subj":"13584","pred":"source","obj":"LitCoin-entities"},{"subj":"13585","pred":"source","obj":"LitCoin-entities"},{"subj":"13586","pred":"source","obj":"LitCoin-entities"},{"subj":"13587","pred":"source","obj":"LitCoin-entities"},{"subj":"13588","pred":"source","obj":"LitCoin-entities"},{"subj":"13589","pred":"source","obj":"LitCoin-entities"},{"subj":"13590","pred":"source","obj":"LitCoin-entities"},{"subj":"13591","pred":"source","obj":"LitCoin-entities"},{"subj":"13592","pred":"source","obj":"LitCoin-entities"},{"subj":"13593","pred":"source","obj":"LitCoin-entities"},{"subj":"13594","pred":"source","obj":"LitCoin-entities"},{"subj":"13595","pred":"source","obj":"LitCoin-entities"},{"subj":"13596","pred":"source","obj":"LitCoin-entities"},{"subj":"13597","pred":"source","obj":"LitCoin-entities"},{"subj":"13598","pred":"source","obj":"LitCoin-entities"},{"subj":"13599","pred":"source","obj":"LitCoin-entities"},{"subj":"13600","pred":"source","obj":"LitCoin-entities"},{"subj":"13601","pred":"source","obj":"LitCoin-entities"},{"subj":"13602","pred":"source","obj":"LitCoin-entities"},{"subj":"13603","pred":"source","obj":"LitCoin-entities"},{"subj":"13604","pred":"source","obj":"LitCoin-entities"},{"subj":"13605","pred":"source","obj":"LitCoin-entities"},{"subj":"13606","pred":"source","obj":"LitCoin-entities"},{"subj":"13607","pred":"source","obj":"LitCoin-entities"},{"subj":"13608","pred":"source","obj":"LitCoin-entities"},{"subj":"13609","pred":"source","obj":"LitCoin-entities"},{"subj":"13610","pred":"source","obj":"LitCoin-entities"},{"subj":"13611","pred":"source","obj":"LitCoin-entities"},{"subj":"13612","pred":"source","obj":"LitCoin-entities"},{"subj":"13613","pred":"source","obj":"LitCoin-entities"},{"subj":"13614","pred":"source","obj":"LitCoin-entities"},{"subj":"13615","pred":"source","obj":"LitCoin-entities"},{"subj":"13616","pred":"source","obj":"LitCoin-entities"},{"subj":"13617","pred":"source","obj":"LitCoin-entities"},{"subj":"13618","pred":"source","obj":"LitCoin-entities"},{"subj":"13619","pred":"source","obj":"LitCoin-entities"},{"subj":"13620","pred":"source","obj":"LitCoin-entities"},{"subj":"13621","pred":"source","obj":"LitCoin-entities"},{"subj":"13622","pred":"source","obj":"LitCoin-entities"},{"subj":"13623","pred":"source","obj":"LitCoin-entities"},{"subj":"13624","pred":"source","obj":"LitCoin-entities"},{"subj":"13625","pred":"source","obj":"LitCoin-entities"},{"subj":"13626","pred":"source","obj":"LitCoin-entities"},{"subj":"13627","pred":"source","obj":"LitCoin-entities"},{"subj":"13628","pred":"source","obj":"LitCoin-entities"},{"subj":"13629","pred":"source","obj":"LitCoin-entities"},{"subj":"13630","pred":"source","obj":"LitCoin-entities"},{"subj":"13631","pred":"source","obj":"LitCoin-entities"},{"subj":"13632","pred":"source","obj":"LitCoin-entities"},{"subj":"13633","pred":"source","obj":"LitCoin-entities"},{"subj":"13634","pred":"source","obj":"LitCoin-entities"},{"subj":"13635","pred":"source","obj":"LitCoin-entities"}],"namespaces":[{"prefix":"_base","uri":"https://w3id.org/biolink/vocab/"},{"prefix":"MESH","uri":"http://id.nlm.nih.gov/mesh/"},{"prefix":"NCBITaxon","uri":"https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id="},{"prefix":"NCBIGene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"OMIM","uri":"https://www.omim.org/entry/"},{"prefix":"DBSNP","uri":"https://www.ncbi.nlm.nih.gov/snp/"}]},{"project":"LitCoin_Mondo","denotations":[{"id":"T1","span":{"begin":310,"end":324},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":601,"end":621},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":1151,"end":1157},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":2360,"end":2374},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A1","pred":"mondo_id","subj":"T1","obj":"0000494"},{"id":"A2","pred":"mondo_id","subj":"T2","obj":"0003329"},{"id":"A3","pred":"mondo_id","subj":"T3","obj":"0021178"},{"id":"A4","pred":"mondo_id","subj":"T4","obj":"0000494"},{"subj":"T1","pred":"source","obj":"LitCoin_Mondo"},{"subj":"T2","pred":"source","obj":"LitCoin_Mondo"},{"subj":"T3","pred":"source","obj":"LitCoin_Mondo"},{"subj":"T4","pred":"source","obj":"LitCoin_Mondo"}]},{"project":"LitCoin-GeneOrGeneProduct-v0","denotations":[{"id":"T1","span":{"begin":70,"end":74},"obj":"GeneOrGeneProduct"},{"id":"T2","span":{"begin":85,"end":89},"obj":"GeneOrGeneProduct"},{"id":"T3","span":{"begin":123,"end":126},"obj":"GeneOrGeneProduct"},{"id":"T4","span":{"begin":134,"end":140},"obj":"GeneOrGeneProduct"},{"id":"T5","span":{"begin":240,"end":250},"obj":"GeneOrGeneProduct"},{"id":"T6","span":{"begin":303,"end":306},"obj":"GeneOrGeneProduct"},{"id":"T7","span":{"begin":399,"end":403},"obj":"GeneOrGeneProduct"},{"id":"T8","span":{"begin":430,"end":433},"obj":"GeneOrGeneProduct"},{"id":"T9","span":{"begin":637,"end":641},"obj":"GeneOrGeneProduct"},{"id":"T10","span":{"begin":647,"end":654},"obj":"GeneOrGeneProduct"},{"id":"T11","span":{"begin":655,"end":659},"obj":"GeneOrGeneProduct"},{"id":"T12","span":{"begin":717,"end":730},"obj":"GeneOrGeneProduct"},{"id":"T13","span":{"begin":785,"end":789},"obj":"GeneOrGeneProduct"},{"id":"T14","span":{"begin":791,"end":795},"obj":"GeneOrGeneProduct"},{"id":"T15","span":{"begin":827,"end":833},"obj":"GeneOrGeneProduct"},{"id":"T16","span":{"begin":926,"end":932},"obj":"GeneOrGeneProduct"},{"id":"T17","span":{"begin":949,"end":959},"obj":"GeneOrGeneProduct"},{"id":"T18","span":{"begin":1021,"end":1029},"obj":"GeneOrGeneProduct"},{"id":"T19","span":{"begin":1042,"end":1051},"obj":"GeneOrGeneProduct"},{"id":"T20","span":{"begin":1070,"end":1073},"obj":"GeneOrGeneProduct"},{"id":"T21","span":{"begin":1124,"end":1127},"obj":"GeneOrGeneProduct"},{"id":"T22","span":{"begin":1180,"end":1193},"obj":"GeneOrGeneProduct"},{"id":"T23","span":{"begin":1194,"end":1200},"obj":"GeneOrGeneProduct"},{"id":"T24","span":{"begin":1229,"end":1237},"obj":"GeneOrGeneProduct"},{"id":"T25","span":{"begin":1244,"end":1252},"obj":"GeneOrGeneProduct"},{"id":"T26","span":{"begin":1270,"end":1273},"obj":"GeneOrGeneProduct"},{"id":"T27","span":{"begin":1399,"end":1402},"obj":"GeneOrGeneProduct"},{"id":"T28","span":{"begin":1404,"end":1412},"obj":"GeneOrGeneProduct"},{"id":"T29","span":{"begin":1422,"end":1427},"obj":"GeneOrGeneProduct"},{"id":"T30","span":{"begin":1429,"end":1433},"obj":"GeneOrGeneProduct"},{"id":"T31","span":{"begin":1441,"end":1448},"obj":"GeneOrGeneProduct"},{"id":"T32","span":{"begin":1472,"end":1482},"obj":"GeneOrGeneProduct"},{"id":"T33","span":{"begin":1498,"end":1501},"obj":"GeneOrGeneProduct"},{"id":"T34","span":{"begin":1507,"end":1514},"obj":"GeneOrGeneProduct"},{"id":"T35","span":{"begin":1585,"end":1589},"obj":"GeneOrGeneProduct"},{"id":"T36","span":{"begin":1609,"end":1613},"obj":"GeneOrGeneProduct"},{"id":"T37","span":{"begin":1614,"end":1618},"obj":"GeneOrGeneProduct"},{"id":"T38","span":{"begin":1677,"end":1681},"obj":"GeneOrGeneProduct"},{"id":"T39","span":{"begin":1684,"end":1688},"obj":"GeneOrGeneProduct"},{"id":"T40","span":{"begin":1740,"end":1743},"obj":"GeneOrGeneProduct"},{"id":"T41","span":{"begin":1818,"end":1822},"obj":"GeneOrGeneProduct"},{"id":"T42","span":{"begin":1844,"end":1851},"obj":"GeneOrGeneProduct"},{"id":"T43","span":{"begin":1862,"end":1869},"obj":"GeneOrGeneProduct"},{"id":"T44","span":{"begin":1870,"end":1877},"obj":"GeneOrGeneProduct"},{"id":"T45","span":{"begin":1879,"end":1883},"obj":"GeneOrGeneProduct"},{"id":"T46","span":{"begin":1928,"end":1931},"obj":"GeneOrGeneProduct"},{"id":"T47","span":{"begin":1951,"end":1957},"obj":"GeneOrGeneProduct"},{"id":"T48","span":{"begin":2034,"end":2041},"obj":"GeneOrGeneProduct"},{"id":"T49","span":{"begin":2073,"end":2080},"obj":"GeneOrGeneProduct"},{"id":"T50","span":{"begin":2085,"end":2089},"obj":"GeneOrGeneProduct"},{"id":"T51","span":{"begin":2090,"end":2095},"obj":"GeneOrGeneProduct"},{"id":"T52","span":{"begin":2110,"end":2113},"obj":"GeneOrGeneProduct"},{"id":"T53","span":{"begin":2203,"end":2207},"obj":"GeneOrGeneProduct"},{"id":"T54","span":{"begin":2218,"end":2222},"obj":"GeneOrGeneProduct"},{"id":"T55","span":{"begin":2306,"end":2309},"obj":"GeneOrGeneProduct"},{"id":"T56","span":{"begin":2321,"end":2326},"obj":"GeneOrGeneProduct"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T2","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T3","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T4","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T5","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T6","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T7","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T8","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T9","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T10","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T11","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T12","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T13","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T14","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T15","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T16","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T17","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T18","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T19","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T20","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T21","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T22","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T23","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T24","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T25","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T26","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T27","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T28","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T29","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T30","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T31","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T32","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T33","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T34","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T35","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T36","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T37","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T38","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T39","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T40","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T41","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T42","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T43","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T44","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T45","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T46","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T47","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T48","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T49","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T50","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T51","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T52","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T53","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T54","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T55","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T56","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"}]},{"project":"LitCoin-GeneOrGeneProduct-v2","denotations":[{"id":"T1","span":{"begin":70,"end":74},"obj":"GeneOrGeneProduct"},{"id":"T2","span":{"begin":85,"end":89},"obj":"GeneOrGeneProduct"},{"id":"T3","span":{"begin":637,"end":641},"obj":"GeneOrGeneProduct"},{"id":"T4","span":{"begin":717,"end":730},"obj":"GeneOrGeneProduct"},{"id":"T5","span":{"begin":785,"end":789},"obj":"GeneOrGeneProduct"},{"id":"T6","span":{"begin":791,"end":795},"obj":"GeneOrGeneProduct"},{"id":"T7","span":{"begin":827,"end":833},"obj":"GeneOrGeneProduct"},{"id":"T8","span":{"begin":1180,"end":1193},"obj":"GeneOrGeneProduct"},{"id":"T9","span":{"begin":1194,"end":1200},"obj":"GeneOrGeneProduct"},{"id":"T10","span":{"begin":1229,"end":1237},"obj":"GeneOrGeneProduct"},{"id":"T11","span":{"begin":1244,"end":1252},"obj":"GeneOrGeneProduct"},{"id":"T12","span":{"begin":1399,"end":1402},"obj":"GeneOrGeneProduct"},{"id":"T13","span":{"begin":1404,"end":1412},"obj":"GeneOrGeneProduct"},{"id":"T14","span":{"begin":1422,"end":1427},"obj":"GeneOrGeneProduct"},{"id":"T15","span":{"begin":1429,"end":1433},"obj":"GeneOrGeneProduct"},{"id":"T16","span":{"begin":1472,"end":1482},"obj":"GeneOrGeneProduct"},{"id":"T17","span":{"begin":1609,"end":1613},"obj":"GeneOrGeneProduct"},{"id":"T18","span":{"begin":1614,"end":1618},"obj":"GeneOrGeneProduct"},{"id":"T19","span":{"begin":1677,"end":1681},"obj":"GeneOrGeneProduct"},{"id":"T20","span":{"begin":1684,"end":1688},"obj":"GeneOrGeneProduct"},{"id":"T21","span":{"begin":1818,"end":1822},"obj":"GeneOrGeneProduct"},{"id":"T22","span":{"begin":1844,"end":1851},"obj":"GeneOrGeneProduct"},{"id":"T23","span":{"begin":1862,"end":1869},"obj":"GeneOrGeneProduct"},{"id":"T24","span":{"begin":1879,"end":1883},"obj":"GeneOrGeneProduct"},{"id":"T25","span":{"begin":1951,"end":1957},"obj":"GeneOrGeneProduct"},{"id":"T26","span":{"begin":2034,"end":2041},"obj":"GeneOrGeneProduct"},{"id":"T27","span":{"begin":2085,"end":2089},"obj":"GeneOrGeneProduct"},{"id":"T28","span":{"begin":2203,"end":2207},"obj":"GeneOrGeneProduct"},{"id":"T29","span":{"begin":2218,"end":2222},"obj":"GeneOrGeneProduct"},{"id":"T30","span":{"begin":2321,"end":2326},"obj":"GeneOrGeneProduct"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T2","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T3","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T4","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T5","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T6","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T7","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T8","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T9","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T10","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T11","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T12","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T13","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T14","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T15","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T16","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T17","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T18","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T19","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T20","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T21","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T22","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T23","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T24","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T25","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T26","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T27","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T28","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T29","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T30","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"}]},{"project":"LitCoin-Disease-MeSH","denotations":[{"id":"T1","span":{"begin":43,"end":51},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":227,"end":239},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":316,"end":324},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":461,"end":469},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T5","span":{"begin":601,"end":621},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T6","span":{"begin":623,"end":626},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T7","span":{"begin":679,"end":687},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T8","span":{"begin":860,"end":872},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T9","span":{"begin":920,"end":932},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T10","span":{"begin":937,"end":945},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T11","span":{"begin":1151,"end":1157},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T12","span":{"begin":1653,"end":1665},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T13","span":{"begin":1766,"end":1774},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T14","span":{"begin":2163,"end":2175},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T15","span":{"begin":2366,"end":2374},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A1","pred":"originalLabel","subj":"T1","obj":"D005355"},{"id":"A7","pred":"originalLabel","subj":"T7","obj":"D005355"},{"id":"A4","pred":"originalLabel","subj":"T4","obj":"D005355"},{"id":"A6","pred":"originalLabel","subj":"T6","obj":"D014517"},{"id":"A5","pred":"originalLabel","subj":"T5","obj":"D014517"},{"id":"A11","pred":"originalLabel","subj":"T11","obj":"D014947"},{"id":"A8","pred":"originalLabel","subj":"T8","obj":"DISEASE"},{"id":"A3","pred":"originalLabel","subj":"T3","obj":"D005355"},{"id":"A9","pred":"originalLabel","subj":"T9","obj":"DISEASE"},{"id":"A12","pred":"originalLabel","subj":"T12","obj":"DISEASE"},{"id":"A14","pred":"originalLabel","subj":"T14","obj":"DISEASE"},{"id":"A2","pred":"originalLabel","subj":"T2","obj":"DISEASE"},{"id":"A15","pred":"originalLabel","subj":"T15","obj":"D005355"},{"id":"A13","pred":"originalLabel","subj":"T13","obj":"D005355"},{"id":"A10","pred":"originalLabel","subj":"T10","obj":"D005355"},{"subj":"T1","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T2","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T3","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T4","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T5","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T6","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T7","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T8","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T9","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T10","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T11","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T12","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T13","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T14","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T15","pred":"source","obj":"LitCoin-Disease-MeSH"}]},{"project":"LitCoin-GeneOrGeneProduct-v3","denotations":[{"id":"T1","span":{"begin":70,"end":74},"obj":"GeneOrGeneProduct"},{"id":"T2","span":{"begin":85,"end":89},"obj":"GeneOrGeneProduct"},{"id":"T3","span":{"begin":717,"end":730},"obj":"GeneOrGeneProduct"},{"id":"T4","span":{"begin":732,"end":735},"obj":"GeneOrGeneProduct"},{"id":"T5","span":{"begin":1229,"end":1237},"obj":"GeneOrGeneProduct"},{"id":"T6","span":{"begin":1244,"end":1252},"obj":"GeneOrGeneProduct"},{"id":"T7","span":{"begin":1399,"end":1402},"obj":"GeneOrGeneProduct"},{"id":"T8","span":{"begin":1404,"end":1412},"obj":"GeneOrGeneProduct"},{"id":"T9","span":{"begin":1414,"end":1417},"obj":"GeneOrGeneProduct"},{"id":"T10","span":{"begin":1422,"end":1427},"obj":"GeneOrGeneProduct"},{"id":"T11","span":{"begin":1429,"end":1433},"obj":"GeneOrGeneProduct"},{"id":"T12","span":{"begin":1472,"end":1482},"obj":"GeneOrGeneProduct"},{"id":"T13","span":{"begin":1609,"end":1613},"obj":"GeneOrGeneProduct"},{"id":"T14","span":{"begin":1677,"end":1681},"obj":"GeneOrGeneProduct"},{"id":"T15","span":{"begin":1684,"end":1688},"obj":"GeneOrGeneProduct"},{"id":"T16","span":{"begin":1818,"end":1822},"obj":"GeneOrGeneProduct"},{"id":"T17","span":{"begin":1844,"end":1869},"obj":"GeneOrGeneProduct"},{"id":"T18","span":{"begin":1879,"end":1883},"obj":"GeneOrGeneProduct"},{"id":"T19","span":{"begin":2203,"end":2207},"obj":"GeneOrGeneProduct"},{"id":"T20","span":{"begin":2218,"end":2222},"obj":"GeneOrGeneProduct"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T2","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T3","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T4","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T5","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T6","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T7","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T8","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T9","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T10","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T11","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T12","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T13","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T14","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T15","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T16","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T17","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T18","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T19","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T20","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"}]},{"project":"LitCoin_Mondo_095","denotations":[{"id":"T1","span":{"begin":310,"end":324},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":643,"end":645},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":1128,"end":1131},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T5","span":{"begin":1151,"end":1157},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T6","span":{"begin":1399,"end":1402},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T7","span":{"begin":2360,"end":2374},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A1","pred":"mondo_id","subj":"T1","obj":"0000494"},{"id":"A2","pred":"mondo_id","subj":"T2","obj":"0100339"},{"id":"A3","pred":"mondo_id","subj":"T2","obj":"0002056"},{"id":"A4","pred":"mondo_id","subj":"T4","obj":"0012833"},{"id":"A5","pred":"mondo_id","subj":"T5","obj":"0021178"},{"id":"A6","pred":"mondo_id","subj":"T6","obj":"0019079"},{"id":"A7","pred":"mondo_id","subj":"T7","obj":"0000494"},{"subj":"T1","pred":"source","obj":"LitCoin_Mondo_095"},{"subj":"T2","pred":"source","obj":"LitCoin_Mondo_095"},{"subj":"T4","pred":"source","obj":"LitCoin_Mondo_095"},{"subj":"T5","pred":"source","obj":"LitCoin_Mondo_095"},{"subj":"T6","pred":"source","obj":"LitCoin_Mondo_095"},{"subj":"T7","pred":"source","obj":"LitCoin_Mondo_095"}]},{"project":"LitCoin-MeSH-Disease-2","denotations":[{"id":"T1","span":{"begin":43,"end":51},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":227,"end":239},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":316,"end":324},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":461,"end":469},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T5","span":{"begin":471,"end":474},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T6","span":{"begin":601,"end":621},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T7","span":{"begin":623,"end":626},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T8","span":{"begin":679,"end":687},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T9","span":{"begin":860,"end":872},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T10","span":{"begin":920,"end":932},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T11","span":{"begin":937,"end":945},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T12","span":{"begin":1082,"end":1085},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T13","span":{"begin":1151,"end":1157},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T14","span":{"begin":1653,"end":1665},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T15","span":{"begin":1766,"end":1774},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T16","span":{"begin":2163,"end":2175},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T17","span":{"begin":2366,"end":2374},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A6","pred":"ID:","subj":"T6","obj":"D014517"},{"id":"A11","pred":"ID:","subj":"T11","obj":"D005355"},{"id":"A5","pred":"ID:","subj":"T5","obj":"DISEASE"},{"id":"A16","pred":"ID:","subj":"T16","obj":"DISEASE"},{"id":"A14","pred":"ID:","subj":"T14","obj":"DISEASE"},{"id":"A7","pred":"ID:","subj":"T7","obj":"D014517"},{"id":"A4","pred":"ID:","subj":"T4","obj":"D005355"},{"id":"A13","pred":"ID:","subj":"T13","obj":"D014947"},{"id":"A12","pred":"ID:","subj":"T12","obj":"DISEASE"},{"id":"A17","pred":"ID:","subj":"T17","obj":"D005355"},{"id":"A2","pred":"ID:","subj":"T2","obj":"DISEASE"},{"id":"A10","pred":"ID:","subj":"T10","obj":"DISEASE"},{"id":"A1","pred":"ID:","subj":"T1","obj":"D005355"},{"id":"A8","pred":"ID:","subj":"T8","obj":"D005355"},{"id":"A9","pred":"ID:","subj":"T9","obj":"DISEASE"},{"id":"A3","pred":"ID:","subj":"T3","obj":"D005355"},{"id":"A15","pred":"ID:","subj":"T15","obj":"D005355"},{"subj":"T1","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T2","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T3","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T4","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T5","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T6","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T7","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T8","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T9","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T10","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T11","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T12","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T13","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T14","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T15","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T16","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T17","pred":"source","obj":"LitCoin-MeSH-Disease-2"}]},{"project":"LitCoin_CellLine","denotations":[{"id":"T1","span":{"begin":791,"end":795},"obj":"CellLine"},{"id":"T2","span":{"begin":2085,"end":2089},"obj":"CellLine"}],"attributes":[{"id":"A1","pred":"cellosaurus_accession_id","subj":"T1","obj":"AddedByYayamamo"},{"id":"A2","pred":"cellosaurus_accession_id","subj":"T2","obj":"AddedByYayamamo"},{"subj":"T1","pred":"source","obj":"LitCoin_CellLine"},{"subj":"T2","pred":"source","obj":"LitCoin_CellLine"}]},{"project":"LitCoin-MONDO_bioort2019","denotations":[{"id":"T1","span":{"begin":43,"end":51},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":316,"end":324},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":461,"end":469},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":471,"end":474},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T5","span":{"begin":601,"end":621},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T6","span":{"begin":623,"end":626},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T7","span":{"begin":679,"end":687},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T8","span":{"begin":920,"end":932},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T9","span":{"begin":937,"end":945},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T10","span":{"begin":1082,"end":1085},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T11","span":{"begin":1766,"end":1774},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T12","span":{"begin":2366,"end":2374},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A6","pred":"#label","subj":"T6","obj":"D014517"},{"id":"A12","pred":"#label","subj":"T12","obj":"D005355"},{"id":"A4","pred":"#label","subj":"T4","obj":"DISEASE"},{"id":"A5","pred":"#label","subj":"T5","obj":"D014517"},{"id":"A9","pred":"#label","subj":"T9","obj":"D005355"},{"id":"A10","pred":"#label","subj":"T10","obj":"DISEASE"},{"id":"A8","pred":"#label","subj":"T8","obj":"DISEASE"},{"id":"A7","pred":"#label","subj":"T7","obj":"D005355"},{"id":"A3","pred":"#label","subj":"T3","obj":"D005355"},{"id":"A1","pred":"#label","subj":"T1","obj":"D005355"},{"id":"A2","pred":"#label","subj":"T2","obj":"D005355"},{"id":"A11","pred":"#label","subj":"T11","obj":"D005355"},{"subj":"T1","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T2","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T3","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T4","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T5","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T6","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T7","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T8","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T9","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T10","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T11","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T12","pred":"source","obj":"LitCoin-MONDO_bioort2019"}]},{"project":"LitCoin-NCBITaxon-2","denotations":[{"id":"T1","span":{"begin":174,"end":188},"obj":"OrganismTaxon"},{"id":"T2","span":{"begin":655,"end":659},"obj":"OrganismTaxon"},{"id":"T3","span":{"begin":751,"end":756},"obj":"OrganismTaxon"},{"id":"T4","span":{"begin":2067,"end":2072},"obj":"OrganismTaxon"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCoin-NCBITaxon-2"},{"subj":"T2","pred":"source","obj":"LitCoin-NCBITaxon-2"},{"subj":"T3","pred":"source","obj":"LitCoin-NCBITaxon-2"},{"subj":"T4","pred":"source","obj":"LitCoin-NCBITaxon-2"}]},{"project":"LitCoin-Chemical-MeSH-CHEBI","denotations":[{"id":"T1","span":{"begin":0,"end":11},"obj":"ChemicalEntity"},{"id":"T2","span":{"begin":110,"end":121},"obj":"ChemicalEntity"},{"id":"T3","span":{"begin":123,"end":126},"obj":"ChemicalEntity"},{"id":"T4","span":{"begin":303,"end":306},"obj":"ChemicalEntity"},{"id":"T5","span":{"begin":430,"end":433},"obj":"ChemicalEntity"},{"id":"T6","span":{"begin":631,"end":641},"obj":"ChemicalEntity"},{"id":"T8","span":{"begin":643,"end":645},"obj":"ChemicalEntity"},{"id":"T9","span":{"begin":1070,"end":1073},"obj":"ChemicalEntity"},{"id":"T10","span":{"begin":1124,"end":1127},"obj":"ChemicalEntity"},{"id":"T11","span":{"begin":1229,"end":1237},"obj":"ChemicalEntity"},{"id":"T12","span":{"begin":1244,"end":1252},"obj":"ChemicalEntity"},{"id":"T13","span":{"begin":1270,"end":1273},"obj":"ChemicalEntity"},{"id":"T14","span":{"begin":1498,"end":1501},"obj":"ChemicalEntity"},{"id":"T15","span":{"begin":1535,"end":1554},"obj":"ChemicalEntity"},{"id":"T16","span":{"begin":1562,"end":1572},"obj":"ChemicalEntity"},{"id":"T18","span":{"begin":1585,"end":1589},"obj":"ChemicalEntity"},{"id":"T20","span":{"begin":1590,"end":1598},"obj":"ChemicalEntity"},{"id":"T22","span":{"begin":1609,"end":1618},"obj":"ChemicalEntity"},{"id":"T24","span":{"begin":1740,"end":1743},"obj":"ChemicalEntity"},{"id":"T25","span":{"begin":1928,"end":1931},"obj":"ChemicalEntity"},{"id":"T26","span":{"begin":2110,"end":2113},"obj":"ChemicalEntity"},{"id":"T27","span":{"begin":2306,"end":2309},"obj":"ChemicalEntity"}],"attributes":[{"id":"A1","pred":"ID:","subj":"T1","obj":"http://purl.obolibrary.org/obo/CHEBI_9009"},{"id":"A2","pred":"ID:","subj":"T2","obj":"http://purl.obolibrary.org/obo/CHEBI_9009"},{"id":"A3","pred":"ID:","subj":"T3","obj":"http://purl.obolibrary.org/obo/CHEBI_9009"},{"id":"A4","pred":"ID:","subj":"T4","obj":"http://purl.obolibrary.org/obo/CHEBI_9009"},{"id":"A5","pred":"ID:","subj":"T5","obj":"http://purl.obolibrary.org/obo/CHEBI_9009"},{"id":"A6","pred":"ID:","subj":"T6","obj":"D005492"},{"id":"A7","pred":"ID:","subj":"T6","obj":"http://purl.obolibrary.org/obo/CHEBI_27470"},{"id":"A8","pred":"ID:","subj":"T8","obj":"D005492"},{"id":"A9","pred":"ID:","subj":"T9","obj":"http://purl.obolibrary.org/obo/CHEBI_9009"},{"id":"A10","pred":"ID:","subj":"T10","obj":"http://purl.obolibrary.org/obo/CHEBI_9009"},{"id":"A11","pred":"ID:","subj":"T11","obj":"http://purl.obolibrary.org/obo/CHEBI_3815"},{"id":"A12","pred":"ID:","subj":"T12","obj":"http://purl.obolibrary.org/obo/CHEBI_3815"},{"id":"A13","pred":"ID:","subj":"T13","obj":"http://purl.obolibrary.org/obo/CHEBI_9009"},{"id":"A14","pred":"ID:","subj":"T14","obj":"http://purl.obolibrary.org/obo/CHEBI_9009"},{"id":"A15","pred":"ID:","subj":"T15","obj":"D015415"},{"id":"A16","pred":"ID:","subj":"T16","obj":"D003404"},{"id":"A17","pred":"ID:","subj":"T16","obj":"http://purl.obolibrary.org/obo/CHEBI_16737"},{"id":"A18","pred":"ID:","subj":"T18","obj":"D014508"},{"id":"A19","pred":"ID:","subj":"T18","obj":"http://purl.obolibrary.org/obo/CHEBI_16199"},{"id":"A20","pred":"ID:","subj":"T20","obj":"D009584"},{"id":"A21","pred":"ID:","subj":"T20","obj":"http://purl.obolibrary.org/obo/CHEBI_25555"},{"id":"A22","pred":"ID:","subj":"T22","obj":"D014527"},{"id":"A23","pred":"ID:","subj":"T22","obj":"http://purl.obolibrary.org/obo/CHEBI_27226"},{"id":"A24","pred":"ID:","subj":"T24","obj":"http://purl.obolibrary.org/obo/CHEBI_9009"},{"id":"A25","pred":"ID:","subj":"T25","obj":"http://purl.obolibrary.org/obo/CHEBI_9009"},{"id":"A26","pred":"ID:","subj":"T26","obj":"http://purl.obolibrary.org/obo/CHEBI_9009"},{"id":"A27","pred":"ID:","subj":"T27","obj":"http://purl.obolibrary.org/obo/CHEBI_9009"},{"subj":"T1","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T2","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T3","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T4","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T5","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T6","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T8","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T9","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T10","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T11","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T12","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T13","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T14","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T15","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T16","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T18","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T20","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T22","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T24","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T25","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T26","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T27","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"}]},{"project":"LitCoin-training-merged","denotations":[{"id":"T2","span":{"begin":2085,"end":2089},"obj":"CellLine"},{"id":"T1","span":{"begin":791,"end":795},"obj":"CellLine"},{"id":"T27","span":{"begin":2306,"end":2309},"obj":"ChemicalEntity"},{"id":"T26","span":{"begin":2110,"end":2113},"obj":"ChemicalEntity"},{"id":"T25","span":{"begin":1928,"end":1931},"obj":"ChemicalEntity"},{"id":"T24","span":{"begin":1740,"end":1743},"obj":"ChemicalEntity"},{"id":"T22","span":{"begin":1609,"end":1618},"obj":"ChemicalEntity"},{"id":"T20","span":{"begin":1590,"end":1598},"obj":"ChemicalEntity"},{"id":"T18","span":{"begin":1585,"end":1589},"obj":"ChemicalEntity"},{"id":"T16","span":{"begin":1562,"end":1572},"obj":"ChemicalEntity"},{"id":"T15","span":{"begin":1535,"end":1554},"obj":"ChemicalEntity"},{"id":"T14","span":{"begin":1498,"end":1501},"obj":"ChemicalEntity"},{"id":"T13","span":{"begin":1270,"end":1273},"obj":"ChemicalEntity"},{"id":"T12","span":{"begin":1244,"end":1252},"obj":"ChemicalEntity"},{"id":"T11","span":{"begin":1229,"end":1237},"obj":"ChemicalEntity"},{"id":"T10","span":{"begin":1124,"end":1127},"obj":"ChemicalEntity"},{"id":"T9","span":{"begin":1070,"end":1073},"obj":"ChemicalEntity"},{"id":"T8","span":{"begin":643,"end":645},"obj":"ChemicalEntity"},{"id":"T6","span":{"begin":631,"end":641},"obj":"ChemicalEntity"},{"id":"T5","span":{"begin":430,"end":433},"obj":"ChemicalEntity"},{"id":"T4","span":{"begin":303,"end":306},"obj":"ChemicalEntity"},{"id":"T3","span":{"begin":123,"end":126},"obj":"ChemicalEntity"},{"id":"T54726","span":{"begin":110,"end":121},"obj":"ChemicalEntity"},{"id":"T22323","span":{"begin":0,"end":11},"obj":"ChemicalEntity"},{"id":"T75005","span":{"begin":2218,"end":2222},"obj":"GeneOrGeneProduct"},{"id":"T19","span":{"begin":2203,"end":2207},"obj":"GeneOrGeneProduct"},{"id":"T70882","span":{"begin":1879,"end":1883},"obj":"GeneOrGeneProduct"},{"id":"T17","span":{"begin":1844,"end":1869},"obj":"GeneOrGeneProduct"},{"id":"T20052","span":{"begin":1818,"end":1822},"obj":"GeneOrGeneProduct"},{"id":"T50299","span":{"begin":1684,"end":1688},"obj":"GeneOrGeneProduct"},{"id":"T40576","span":{"begin":1677,"end":1681},"obj":"GeneOrGeneProduct"},{"id":"T86715","span":{"begin":1609,"end":1613},"obj":"GeneOrGeneProduct"},{"id":"T74657","span":{"begin":1472,"end":1482},"obj":"GeneOrGeneProduct"},{"id":"T15367","span":{"begin":1429,"end":1433},"obj":"GeneOrGeneProduct"},{"id":"T55399","span":{"begin":1422,"end":1427},"obj":"GeneOrGeneProduct"},{"id":"T34546","span":{"begin":1414,"end":1417},"obj":"GeneOrGeneProduct"},{"id":"T5269","span":{"begin":1404,"end":1412},"obj":"GeneOrGeneProduct"},{"id":"T7","span":{"begin":1399,"end":1402},"obj":"GeneOrGeneProduct"},{"id":"T76765","span":{"begin":1244,"end":1252},"obj":"GeneOrGeneProduct"},{"id":"T44675","span":{"begin":1229,"end":1237},"obj":"GeneOrGeneProduct"},{"id":"T49127","span":{"begin":732,"end":735},"obj":"GeneOrGeneProduct"},{"id":"T2676","span":{"begin":717,"end":730},"obj":"GeneOrGeneProduct"},{"id":"T13639","span":{"begin":85,"end":89},"obj":"GeneOrGeneProduct"},{"id":"T95036","span":{"begin":70,"end":74},"obj":"GeneOrGeneProduct"},{"id":"T99492","span":{"begin":2366,"end":2374},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T49249","span":{"begin":1766,"end":1774},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T32591","span":{"begin":1082,"end":1085},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T96043","span":{"begin":937,"end":945},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T80306","span":{"begin":920,"end":932},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T59604","span":{"begin":679,"end":687},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T66543","span":{"begin":623,"end":626},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T20591","span":{"begin":601,"end":621},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T31340","span":{"begin":471,"end":474},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T16261","span":{"begin":461,"end":469},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T20737","span":{"begin":316,"end":324},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T29477","span":{"begin":43,"end":51},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T52574","span":{"begin":2067,"end":2072},"obj":"OrganismTaxon"},{"id":"T77668","span":{"begin":751,"end":756},"obj":"OrganismTaxon"},{"id":"T93724","span":{"begin":655,"end":659},"obj":"OrganismTaxon"},{"id":"T38027","span":{"begin":174,"end":188},"obj":"OrganismTaxon"}],"attributes":[{"id":"A5","pred":"ID:","subj":"T5","obj":"http://purl.obolibrary.org/obo/CHEBI_9009"},{"id":"A85823","pred":"#label","subj":"T20591","obj":"D014517"},{"id":"A4","pred":"ID:","subj":"T4","obj":"http://purl.obolibrary.org/obo/CHEBI_9009"},{"id":"A1","pred":"cellosaurus_accession_id","subj":"T1","obj":"AddedByYayamamo"},{"id":"A11","pred":"ID:","subj":"T11","obj":"http://purl.obolibrary.org/obo/CHEBI_3815"},{"id":"A26","pred":"ID:","subj":"T26","obj":"http://purl.obolibrary.org/obo/CHEBI_9009"},{"id":"A23","pred":"ID:","subj":"T22","obj":"http://purl.obolibrary.org/obo/CHEBI_27226"},{"id":"A22","pred":"ID:","subj":"T22","obj":"D014527"},{"id":"A15","pred":"ID:","subj":"T15","obj":"D015415"},{"id":"A10","pred":"ID:","subj":"T10","obj":"http://purl.obolibrary.org/obo/CHEBI_9009"},{"id":"A73881","pred":"#label","subj":"T96043","obj":"D005355"},{"id":"A27","pred":"ID:","subj":"T27","obj":"http://purl.obolibrary.org/obo/CHEBI_9009"},{"id":"A67609","pred":"#label","subj":"T80306","obj":"DISEASE"},{"id":"A25","pred":"ID:","subj":"T25","obj":"http://purl.obolibrary.org/obo/CHEBI_9009"},{"id":"A2","pred":"cellosaurus_accession_id","subj":"T2","obj":"AddedByYayamamo"},{"id":"A21","pred":"ID:","subj":"T20","obj":"http://purl.obolibrary.org/obo/CHEBI_25555"},{"id":"A20","pred":"ID:","subj":"T20","obj":"D009584"},{"id":"A13","pred":"ID:","subj":"T13","obj":"http://purl.obolibrary.org/obo/CHEBI_9009"},{"id":"A68177","pred":"#label","subj":"T32591","obj":"DISEASE"},{"id":"A92662","pred":"#label","subj":"T20737","obj":"D005355"},{"id":"A3","pred":"ID:","subj":"T3","obj":"http://purl.obolibrary.org/obo/CHEBI_9009"},{"id":"A24","pred":"ID:","subj":"T24","obj":"http://purl.obolibrary.org/obo/CHEBI_9009"},{"id":"A14","pred":"ID:","subj":"T14","obj":"http://purl.obolibrary.org/obo/CHEBI_9009"},{"id":"A9","pred":"ID:","subj":"T9","obj":"http://purl.obolibrary.org/obo/CHEBI_9009"},{"id":"A96498","pred":"ID:","subj":"T22323","obj":"http://purl.obolibrary.org/obo/CHEBI_9009"},{"id":"A15410","pred":"#label","subj":"T59604","obj":"D005355"},{"id":"A41596","pred":"#label","subj":"T16261","obj":"D005355"},{"id":"A17","pred":"ID:","subj":"T16","obj":"http://purl.obolibrary.org/obo/CHEBI_16737"},{"id":"A16","pred":"ID:","subj":"T16","obj":"D003404"},{"id":"A65872","pred":"ID:","subj":"T54726","obj":"http://purl.obolibrary.org/obo/CHEBI_9009"},{"id":"A8","pred":"ID:","subj":"T8","obj":"D005492"},{"id":"A19","pred":"ID:","subj":"T18","obj":"http://purl.obolibrary.org/obo/CHEBI_16199"},{"id":"A18","pred":"ID:","subj":"T18","obj":"D014508"},{"id":"A60405","pred":"#label","subj":"T99492","obj":"D005355"},{"id":"A7","pred":"ID:","subj":"T6","obj":"http://purl.obolibrary.org/obo/CHEBI_27470"},{"id":"A6","pred":"ID:","subj":"T6","obj":"D005492"},{"id":"A39292","pred":"#label","subj":"T29477","obj":"D005355"},{"id":"A868","pred":"#label","subj":"T49249","obj":"D005355"},{"id":"A12","pred":"ID:","subj":"T12","obj":"http://purl.obolibrary.org/obo/CHEBI_3815"},{"id":"A82376","pred":"#label","subj":"T31340","obj":"DISEASE"},{"id":"A6934","pred":"#label","subj":"T66543","obj":"D014517"},{"subj":"T2","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T1","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T27","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T26","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T25","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T24","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T22","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T20","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T18","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T16","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T15","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T14","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T13","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T12","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T11","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T10","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T9","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T8","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T6","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T5","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T4","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T3","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T54726","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T22323","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T75005","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T19","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T70882","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T17","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T20052","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T50299","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T40576","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T86715","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T74657","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T15367","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T55399","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T34546","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T5269","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T7","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T76765","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T44675","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T49127","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T2676","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T13639","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T95036","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T99492","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T49249","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T32591","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T96043","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T80306","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T59604","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T66543","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T20591","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T31340","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T16261","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T20737","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T29477","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T52574","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T77668","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T93724","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T38027","pred":"source","obj":"LitCoin-training-merged"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"Inflammaging","color":"#93a1ec","default":true},{"id":"LitCoin-entities-OrganismTaxon-PD","color":"#bbec93"},{"id":"LitCoin-sentences","color":"#ec93d5"},{"id":"LitCoin-entities","color":"#93ece9"},{"id":"LitCoin_Mondo","color":"#eccf93"},{"id":"LitCoin-GeneOrGeneProduct-v0","color":"#b593ec"},{"id":"LitCoin-GeneOrGeneProduct-v2","color":"#93ec9b"},{"id":"LitCoin-Disease-MeSH","color":"#ec93a4"},{"id":"LitCoin-GeneOrGeneProduct-v3","color":"#93beec"},{"id":"LitCoin_Mondo_095","color":"#d9ec93"},{"id":"LitCoin-MeSH-Disease-2","color":"#e593ec"},{"id":"LitCoin_CellLine","color":"#93eccb"},{"id":"LitCoin-MONDO_bioort2019","color":"#ecb193"},{"id":"LitCoin-NCBITaxon-2","color":"#9793ec"},{"id":"LitCoin-Chemical-MeSH-CHEBI","color":"#a8ec93"},{"id":"LitCoin-training-merged","color":"#ec93c2"}]}]}}