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Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-109 Sentence denotes Salidroside Ameliorates Renal Interstitial Fibrosis by Inhibiting the TLR4/NF-κB and MAPK Signaling Pathways.
T2 110-281 Sentence denotes Salidroside (Sal) is an active ingredient that is isolated from Rhodiola rosea, which has been reported to have anti-inflammatory activities and a renal protective effect.
T3 282-353 Sentence denotes However, the role of Sal on renal fibrosis has not yet been elucidated.
T4 354-557 Sentence denotes Here, the purpose of the current study is to test the protective effects of Sal against renal interstitial fibrosis (RIF), and to explore the underlying mechanisms using both in vivo and in vitro models.
T5 558-812 Sentence denotes In this study, we establish the unilateral ureteric obstruction (UUO) or folic acid (FA)-induced mice renal interstitial fibrosis in vivo and the transforming growth factor (TGF)-β1-stimulated human proximal tubular epithelial cell (HK-2) model in vitro.
T6 813-905 Sentence denotes The levels of kidney functional parameters and inflammatory cytokines in serum are examined.
T7 906-987 Sentence denotes The degree of renal damage and fibrosis is determined by histological assessment.
T8 988-1086 Sentence denotes Immunohistochemistry and western blotting are used to determine the mechanisms of Sal against RIF.
T9 1087-1256 Sentence denotes Our results show that treatment with Sal can ameliorate tubular injury and deposition of the extracellular matrix (ECM) components (including collagen Ш and collagen I).
T10 1257-1483 Sentence denotes Furthermore, Sal administration significantly suppresses epithelial-mesenchymal transition (EMT), as evidenced by a decreased expression of α-SMA, vimentin, TGF-β1, snail, slug, and a largely restored expression of E-cadherin.
T11 1484-1697 Sentence denotes Additionally, Sal also reduces the levels of serum biochemical markers (serum creatinine, Scr; blood urea nitrogen, BUN; and uric acid, UA) and decreases the release of inflammatory cytokines (IL-1β, IL-6, TNF-α).
T12 1698-1912 Sentence denotes Further study revealed that the effect of Sal on renal interstitial fibrosis is associated with the lower expression of TLR4, p-IκBα, p-NF-κB and mitogen-activated protein kinases (MAPK), both in vivo and in vitro.
T13 1913-2096 Sentence denotes In conclusion, Sal treatment improves kidney function, ameliorates the deposition of the ECM components and relieves the protein levels of EMT markers in mouse kidneys and HK-2 cells.
T14 2097-2242 Sentence denotes Furthermore, Sal treatment significantly decreases the release of inflammatory cytokines and inhibits the TLR4/NF-κB and MAPK signaling pathways.
T15 2243-2375 Sentence denotes Collectively, these results suggest that the administration of Sal could be a novel therapeutic strategy in treating renal fibrosis.
T1 0-109 Sentence denotes Salidroside Ameliorates Renal Interstitial Fibrosis by Inhibiting the TLR4/NF-κB and MAPK Signaling Pathways.
T2 110-281 Sentence denotes Salidroside (Sal) is an active ingredient that is isolated from Rhodiola rosea, which has been reported to have anti-inflammatory activities and a renal protective effect.
T3 282-353 Sentence denotes However, the role of Sal on renal fibrosis has not yet been elucidated.
T4 354-557 Sentence denotes Here, the purpose of the current study is to test the protective effects of Sal against renal interstitial fibrosis (RIF), and to explore the underlying mechanisms using both in vivo and in vitro models.
T5 558-812 Sentence denotes In this study, we establish the unilateral ureteric obstruction (UUO) or folic acid (FA)-induced mice renal interstitial fibrosis in vivo and the transforming growth factor (TGF)-β1-stimulated human proximal tubular epithelial cell (HK-2) model in vitro.
T6 813-905 Sentence denotes The levels of kidney functional parameters and inflammatory cytokines in serum are examined.
T7 906-987 Sentence denotes The degree of renal damage and fibrosis is determined by histological assessment.
T8 988-1086 Sentence denotes Immunohistochemistry and western blotting are used to determine the mechanisms of Sal against RIF.
T9 1087-1256 Sentence denotes Our results show that treatment with Sal can ameliorate tubular injury and deposition of the extracellular matrix (ECM) components (including collagen Ш and collagen I).
T10 1257-1483 Sentence denotes Furthermore, Sal administration significantly suppresses epithelial-mesenchymal transition (EMT), as evidenced by a decreased expression of α-SMA, vimentin, TGF-β1, snail, slug, and a largely restored expression of E-cadherin.
T11 1484-1697 Sentence denotes Additionally, Sal also reduces the levels of serum biochemical markers (serum creatinine, Scr; blood urea nitrogen, BUN; and uric acid, UA) and decreases the release of inflammatory cytokines (IL-1β, IL-6, TNF-α).
T12 1698-1912 Sentence denotes Further study revealed that the effect of Sal on renal interstitial fibrosis is associated with the lower expression of TLR4, p-IκBα, p-NF-κB and mitogen-activated protein kinases (MAPK), both in vivo and in vitro.
T13 1913-2096 Sentence denotes In conclusion, Sal treatment improves kidney function, ameliorates the deposition of the ECM components and relieves the protein levels of EMT markers in mouse kidneys and HK-2 cells.
T14 2097-2242 Sentence denotes Furthermore, Sal treatment significantly decreases the release of inflammatory cytokines and inhibits the TLR4/NF-κB and MAPK signaling pathways.
T15 2243-2375 Sentence denotes Collectively, these results suggest that the administration of Sal could be a novel therapeutic strategy in treating renal fibrosis.

LitCoin-entities-OrganismTaxon-PD

Id Subject Object Predicate Lexical cue db_id
T1 174-188 OrganismTaxon denotes Rhodiola rosea NCBItxid:203015
T2 655-659 OrganismTaxon denotes mice NCBItxid:10095|NCBItxid:10088
T4 751-756 OrganismTaxon denotes human NCBItxid:9606
T5 2067-2072 OrganismTaxon denotes mouse NCBItxid:10090|NCBItxid:10088

LitCoin-sentences

Id Subject Object Predicate Lexical cue
T1 0-109 Sentence denotes Salidroside Ameliorates Renal Interstitial Fibrosis by Inhibiting the TLR4/NF-κB and MAPK Signaling Pathways.
T2 110-281 Sentence denotes Salidroside (Sal) is an active ingredient that is isolated from Rhodiola rosea, which has been reported to have anti-inflammatory activities and a renal protective effect.
T3 282-353 Sentence denotes However, the role of Sal on renal fibrosis has not yet been elucidated.
T4 354-557 Sentence denotes Here, the purpose of the current study is to test the protective effects of Sal against renal interstitial fibrosis (RIF), and to explore the underlying mechanisms using both in vivo and in vitro models.
T5 558-812 Sentence denotes In this study, we establish the unilateral ureteric obstruction (UUO) or folic acid (FA)-induced mice renal interstitial fibrosis in vivo and the transforming growth factor (TGF)-β1-stimulated human proximal tubular epithelial cell (HK-2) model in vitro.
T6 813-905 Sentence denotes The levels of kidney functional parameters and inflammatory cytokines in serum are examined.
T7 906-987 Sentence denotes The degree of renal damage and fibrosis is determined by histological assessment.
T8 988-1086 Sentence denotes Immunohistochemistry and western blotting are used to determine the mechanisms of Sal against RIF.
T9 1087-1256 Sentence denotes Our results show that treatment with Sal can ameliorate tubular injury and deposition of the extracellular matrix (ECM) components (including collagen Ш and collagen I).
T10 1257-1483 Sentence denotes Furthermore, Sal administration significantly suppresses epithelial-mesenchymal transition (EMT), as evidenced by a decreased expression of α-SMA, vimentin, TGF-β1, snail, slug, and a largely restored expression of E-cadherin.
T11 1484-1697 Sentence denotes Additionally, Sal also reduces the levels of serum biochemical markers (serum creatinine, Scr; blood urea nitrogen, BUN; and uric acid, UA) and decreases the release of inflammatory cytokines (IL-1β, IL-6, TNF-α).
T12 1698-1912 Sentence denotes Further study revealed that the effect of Sal on renal interstitial fibrosis is associated with the lower expression of TLR4, p-IκBα, p-NF-κB and mitogen-activated protein kinases (MAPK), both in vivo and in vitro.
T13 1913-2096 Sentence denotes In conclusion, Sal treatment improves kidney function, ameliorates the deposition of the ECM components and relieves the protein levels of EMT markers in mouse kidneys and HK-2 cells.
T14 2097-2242 Sentence denotes Furthermore, Sal treatment significantly decreases the release of inflammatory cytokines and inhibits the TLR4/NF-κB and MAPK signaling pathways.
T15 2243-2375 Sentence denotes Collectively, these results suggest that the administration of Sal could be a novel therapeutic strategy in treating renal fibrosis.

LitCoin-entities

Id Subject Object Predicate Lexical cue db_id
13570 0-11 ChemicalEntity denotes Salidroside MESH:C009172
13571 24-51 DiseaseOrPhenotypicFeature denotes Renal Interstitial Fibrosis MESH:D007674
13572 70-74 GeneOrGeneProduct denotes TLR4 NCBIGene:21898|NCBIGene:7099
13573 75-80 GeneOrGeneProduct denotes NF-κB NCBIGene:18033|NCBIGene:4790
13574 85-89 GeneOrGeneProduct denotes MAPK NCBIGene:26413|NCBIGene:5594
13575 110-121 ChemicalEntity denotes Salidroside MESH:C009172
13576 123-126 ChemicalEntity denotes Sal MESH:C009172
13577 174-188 OrganismTaxon denotes Rhodiola rosea NCBITaxon:203015
13578 227-239 DiseaseOrPhenotypicFeature denotes inflammatory MESH:D007249
13579 303-306 ChemicalEntity denotes Sal MESH:C009172
13580 310-324 DiseaseOrPhenotypicFeature denotes renal fibrosis MESH:D007674
13581 430-433 ChemicalEntity denotes Sal MESH:C009172
13582 442-469 DiseaseOrPhenotypicFeature denotes renal interstitial fibrosis MESH:D007674
13583 471-474 DiseaseOrPhenotypicFeature denotes RIF MESH:D007674
13584 590-621 DiseaseOrPhenotypicFeature denotes unilateral ureteric obstruction MESH:D014517
13585 623-626 DiseaseOrPhenotypicFeature denotes UUO MESH:D014517
13586 631-641 ChemicalEntity denotes folic acid MESH:D005492
13587 643-645 ChemicalEntity denotes FA MESH:D005492
13588 655-659 OrganismTaxon denotes mice NCBITaxon:10090
13589 660-687 DiseaseOrPhenotypicFeature denotes renal interstitial fibrosis MESH:D007674
13590 704-739 GeneOrGeneProduct denotes transforming growth factor (TGF)-β1 NCBIGene:21803
13591 751-756 OrganismTaxon denotes human NCBITaxon:9606
13592 791-795 CellLine denotes HK-2 NCBITaxon:9606
13593 860-872 DiseaseOrPhenotypicFeature denotes inflammatory MESH:D007249
13594 920-932 DiseaseOrPhenotypicFeature denotes renal damage MESH:D007674
13595 937-945 DiseaseOrPhenotypicFeature denotes fibrosis MESH:D005355
13596 1070-1073 ChemicalEntity denotes Sal MESH:C009172
13597 1082-1085 DiseaseOrPhenotypicFeature denotes RIF MESH:D007674
13598 1124-1127 ChemicalEntity denotes Sal MESH:C009172
13599 1143-1157 DiseaseOrPhenotypicFeature denotes tubular injury MESH:D007674
13600 1229-1239 GeneOrGeneProduct denotes collagen Ш NCBIGene:1281|NCBIGene:12825
13601 1244-1254 GeneOrGeneProduct denotes collagen I NCBIGene:1277|NCBIGene:1278|NCBIGene:12842|NCBIGene:12843
13602 1270-1273 ChemicalEntity denotes Sal MESH:C009172
13603 1397-1402 GeneOrGeneProduct denotes α-SMA NCBIGene:11475|NCBIGene:59
13604 1404-1412 GeneOrGeneProduct denotes vimentin NCBIGene:22352|NCBIGene:7431
13605 1414-1420 GeneOrGeneProduct denotes TGF-β1 NCBIGene:21803|NCBIGene:7040
13606 1422-1427 GeneOrGeneProduct denotes snail NCBIGene:20613|NCBIGene:6615
13607 1429-1433 GeneOrGeneProduct denotes slug NCBIGene:20583|NCBIGene:6591
13608 1472-1482 GeneOrGeneProduct denotes E-cadherin NCBIGene:12550|NCBIGene:999
13609 1498-1501 ChemicalEntity denotes Sal MESH:C009172
13610 1562-1572 ChemicalEntity denotes creatinine MESH:D003404
13611 1585-1589 ChemicalEntity denotes urea MESH:D014508
13612 1590-1598 ChemicalEntity denotes nitrogen MESH:D009584
13613 1609-1618 ChemicalEntity denotes uric acid MESH:D014527
13614 1620-1622 ChemicalEntity denotes UA MESH:D014527
13615 1653-1665 DiseaseOrPhenotypicFeature denotes inflammatory MESH:D007249
13616 1677-1682 GeneOrGeneProduct denotes IL-1β NCBIGene:16176|NCBIGene:3553
13617 1684-1688 GeneOrGeneProduct denotes IL-6 NCBIGene:16193|NCBIGene:3569
13618 1690-1695 GeneOrGeneProduct denotes TNF-α NCBIGene:21926|NCBIGene:7124
13619 1740-1743 ChemicalEntity denotes Sal MESH:C009172
13620 1747-1774 DiseaseOrPhenotypicFeature denotes renal interstitial fibrosis MESH:D007674
13621 1818-1822 GeneOrGeneProduct denotes TLR4 NCBIGene:21898|NCBIGene:7099
13622 1826-1830 GeneOrGeneProduct denotes IκBα NCBIGene:18035|NCBIGene:4792
13623 1834-1839 GeneOrGeneProduct denotes NF-κB NCBIGene:18033|NCBIGene:4790
13624 1844-1877 GeneOrGeneProduct denotes mitogen-activated protein kinases NCBIGene:26413|NCBIGene:5594
13625 1879-1883 GeneOrGeneProduct denotes MAPK NCBIGene:26413|NCBIGene:5594
13626 1928-1931 ChemicalEntity denotes Sal MESH:C009172
13627 2067-2072 OrganismTaxon denotes mouse NCBITaxon:10090
13628 2085-2089 CellLine denotes HK-2 NCBITaxon:9606
13629 2110-2113 ChemicalEntity denotes Sal MESH:C009172
13630 2163-2175 DiseaseOrPhenotypicFeature denotes inflammatory MESH:D007249
13631 2203-2207 GeneOrGeneProduct denotes TLR4 NCBIGene:21898|NCBIGene:7099
13632 2208-2213 GeneOrGeneProduct denotes NF-κB NCBIGene:18033|NCBIGene:4790
13633 2218-2222 GeneOrGeneProduct denotes MAPK NCBIGene:26413|NCBIGene:5594
13634 2306-2309 ChemicalEntity denotes Sal MESH:C009172
13635 2360-2374 DiseaseOrPhenotypicFeature denotes renal fibrosis MESH:D007674

LitCoin_Mondo

Id Subject Object Predicate Lexical cue mondo_id
T1 310-324 DiseaseOrPhenotypicFeature denotes renal fibrosis 0000494
T2 601-621 DiseaseOrPhenotypicFeature denotes ureteric obstruction 0003329
T3 1151-1157 DiseaseOrPhenotypicFeature denotes injury 0021178
T4 2360-2374 DiseaseOrPhenotypicFeature denotes renal fibrosis 0000494

LitCoin-GeneOrGeneProduct-v0

Id Subject Object Predicate Lexical cue
T1 70-74 GeneOrGeneProduct denotes TLR4
T2 85-89 GeneOrGeneProduct denotes MAPK
T3 123-126 GeneOrGeneProduct denotes Sal
T4 134-140 GeneOrGeneProduct denotes active
T5 240-250 GeneOrGeneProduct denotes activities
T6 303-306 GeneOrGeneProduct denotes Sal
T7 399-403 GeneOrGeneProduct denotes test
T8 430-433 GeneOrGeneProduct denotes Sal
T9 637-641 GeneOrGeneProduct denotes acid
T10 647-654 GeneOrGeneProduct denotes induced
T11 655-659 GeneOrGeneProduct denotes mice
T12 717-730 GeneOrGeneProduct denotes growth factor
T13 785-789 GeneOrGeneProduct denotes cell
T14 791-795 GeneOrGeneProduct denotes HK-2
T15 827-833 GeneOrGeneProduct denotes kidney
T16 926-932 GeneOrGeneProduct denotes damage
T17 949-959 GeneOrGeneProduct denotes determined
T18 1021-1029 GeneOrGeneProduct denotes blotting
T19 1042-1051 GeneOrGeneProduct denotes determine
T20 1070-1073 GeneOrGeneProduct denotes Sal
T21 1124-1127 GeneOrGeneProduct denotes Sal
T22 1180-1193 GeneOrGeneProduct denotes extracellular
T23 1194-1200 GeneOrGeneProduct denotes matrix
T24 1229-1237 GeneOrGeneProduct denotes collagen
T25 1244-1252 GeneOrGeneProduct denotes collagen
T26 1270-1273 GeneOrGeneProduct denotes Sal
T27 1399-1402 GeneOrGeneProduct denotes SMA
T28 1404-1412 GeneOrGeneProduct denotes vimentin
T29 1422-1427 GeneOrGeneProduct denotes snail
T30 1429-1433 GeneOrGeneProduct denotes slug
T31 1441-1448 GeneOrGeneProduct denotes largely
T32 1472-1482 GeneOrGeneProduct denotes E-cadherin
T33 1498-1501 GeneOrGeneProduct denotes Sal
T34 1507-1514 GeneOrGeneProduct denotes reduces
T35 1585-1589 GeneOrGeneProduct denotes urea
T36 1609-1613 GeneOrGeneProduct denotes uric
T37 1614-1618 GeneOrGeneProduct denotes acid
T38 1677-1681 GeneOrGeneProduct denotes IL-1
T39 1684-1688 GeneOrGeneProduct denotes IL-6
T40 1740-1743 GeneOrGeneProduct denotes Sal
T41 1818-1822 GeneOrGeneProduct denotes TLR4
T42 1844-1851 GeneOrGeneProduct denotes mitogen
T43 1862-1869 GeneOrGeneProduct denotes protein
T44 1870-1877 GeneOrGeneProduct denotes kinases
T45 1879-1883 GeneOrGeneProduct denotes MAPK
T46 1928-1931 GeneOrGeneProduct denotes Sal
T47 1951-1957 GeneOrGeneProduct denotes kidney
T48 2034-2041 GeneOrGeneProduct denotes protein
T49 2073-2080 GeneOrGeneProduct denotes kidneys
T50 2085-2089 GeneOrGeneProduct denotes HK-2
T51 2090-2095 GeneOrGeneProduct denotes cells
T52 2110-2113 GeneOrGeneProduct denotes Sal
T53 2203-2207 GeneOrGeneProduct denotes TLR4
T54 2218-2222 GeneOrGeneProduct denotes MAPK
T55 2306-2309 GeneOrGeneProduct denotes Sal
T56 2321-2326 GeneOrGeneProduct denotes novel

LitCoin-GeneOrGeneProduct-v2

Id Subject Object Predicate Lexical cue
T1 70-74 GeneOrGeneProduct denotes TLR4
T2 85-89 GeneOrGeneProduct denotes MAPK
T3 637-641 GeneOrGeneProduct denotes acid
T4 717-730 GeneOrGeneProduct denotes growth factor
T5 785-789 GeneOrGeneProduct denotes cell
T6 791-795 GeneOrGeneProduct denotes HK-2
T7 827-833 GeneOrGeneProduct denotes kidney
T8 1180-1193 GeneOrGeneProduct denotes extracellular
T9 1194-1200 GeneOrGeneProduct denotes matrix
T10 1229-1237 GeneOrGeneProduct denotes collagen
T11 1244-1252 GeneOrGeneProduct denotes collagen
T12 1399-1402 GeneOrGeneProduct denotes SMA
T13 1404-1412 GeneOrGeneProduct denotes vimentin
T14 1422-1427 GeneOrGeneProduct denotes snail
T15 1429-1433 GeneOrGeneProduct denotes slug
T16 1472-1482 GeneOrGeneProduct denotes E-cadherin
T17 1609-1613 GeneOrGeneProduct denotes uric
T18 1614-1618 GeneOrGeneProduct denotes acid
T19 1677-1681 GeneOrGeneProduct denotes IL-1
T20 1684-1688 GeneOrGeneProduct denotes IL-6
T21 1818-1822 GeneOrGeneProduct denotes TLR4
T22 1844-1851 GeneOrGeneProduct denotes mitogen
T23 1862-1869 GeneOrGeneProduct denotes protein
T24 1879-1883 GeneOrGeneProduct denotes MAPK
T25 1951-1957 GeneOrGeneProduct denotes kidney
T26 2034-2041 GeneOrGeneProduct denotes protein
T27 2085-2089 GeneOrGeneProduct denotes HK-2
T28 2203-2207 GeneOrGeneProduct denotes TLR4
T29 2218-2222 GeneOrGeneProduct denotes MAPK
T30 2321-2326 GeneOrGeneProduct denotes novel

LitCoin-Disease-MeSH

Id Subject Object Predicate Lexical cue originalLabel
T1 43-51 DiseaseOrPhenotypicFeature denotes Fibrosis D005355
T2 227-239 DiseaseOrPhenotypicFeature denotes inflammatory DISEASE
T3 316-324 DiseaseOrPhenotypicFeature denotes fibrosis D005355
T4 461-469 DiseaseOrPhenotypicFeature denotes fibrosis D005355
T5 601-621 DiseaseOrPhenotypicFeature denotes ureteric obstruction D014517
T6 623-626 DiseaseOrPhenotypicFeature denotes UUO D014517
T7 679-687 DiseaseOrPhenotypicFeature denotes fibrosis D005355
T8 860-872 DiseaseOrPhenotypicFeature denotes inflammatory DISEASE
T9 920-932 DiseaseOrPhenotypicFeature denotes renal damage DISEASE
T10 937-945 DiseaseOrPhenotypicFeature denotes fibrosis D005355
T11 1151-1157 DiseaseOrPhenotypicFeature denotes injury D014947
T12 1653-1665 DiseaseOrPhenotypicFeature denotes inflammatory DISEASE
T13 1766-1774 DiseaseOrPhenotypicFeature denotes fibrosis D005355
T14 2163-2175 DiseaseOrPhenotypicFeature denotes inflammatory DISEASE
T15 2366-2374 DiseaseOrPhenotypicFeature denotes fibrosis D005355

LitCoin-GeneOrGeneProduct-v3

Id Subject Object Predicate Lexical cue
T1 70-74 GeneOrGeneProduct denotes TLR4
T2 85-89 GeneOrGeneProduct denotes MAPK
T3 717-730 GeneOrGeneProduct denotes growth factor
T4 732-735 GeneOrGeneProduct denotes TGF
T5 1229-1237 GeneOrGeneProduct denotes collagen
T6 1244-1252 GeneOrGeneProduct denotes collagen
T7 1399-1402 GeneOrGeneProduct denotes SMA
T8 1404-1412 GeneOrGeneProduct denotes vimentin
T9 1414-1417 GeneOrGeneProduct denotes TGF
T10 1422-1427 GeneOrGeneProduct denotes snail
T11 1429-1433 GeneOrGeneProduct denotes slug
T12 1472-1482 GeneOrGeneProduct denotes E-cadherin
T13 1609-1613 GeneOrGeneProduct denotes uric
T14 1677-1681 GeneOrGeneProduct denotes IL-1
T15 1684-1688 GeneOrGeneProduct denotes IL-6
T16 1818-1822 GeneOrGeneProduct denotes TLR4
T17 1844-1869 GeneOrGeneProduct denotes mitogen-activated protein
T18 1879-1883 GeneOrGeneProduct denotes MAPK
T19 2203-2207 GeneOrGeneProduct denotes TLR4
T20 2218-2222 GeneOrGeneProduct denotes MAPK

LitCoin_Mondo_095

Id Subject Object Predicate Lexical cue mondo_id
T1 310-324 DiseaseOrPhenotypicFeature denotes renal fibrosis 0000494
T2 643-645 DiseaseOrPhenotypicFeature denotes FA 0100339|0002056
T4 1128-1131 DiseaseOrPhenotypicFeature denotes can 0012833
T5 1151-1157 DiseaseOrPhenotypicFeature denotes injury 0021178
T6 1399-1402 DiseaseOrPhenotypicFeature denotes SMA 0019079
T7 2360-2374 DiseaseOrPhenotypicFeature denotes renal fibrosis 0000494

LitCoin-MeSH-Disease-2

Id Subject Object Predicate Lexical cue ID:
T1 43-51 DiseaseOrPhenotypicFeature denotes Fibrosis D005355
T2 227-239 DiseaseOrPhenotypicFeature denotes inflammatory DISEASE
T3 316-324 DiseaseOrPhenotypicFeature denotes fibrosis D005355
T4 461-469 DiseaseOrPhenotypicFeature denotes fibrosis D005355
T5 471-474 DiseaseOrPhenotypicFeature denotes RIF DISEASE
T6 601-621 DiseaseOrPhenotypicFeature denotes ureteric obstruction D014517
T7 623-626 DiseaseOrPhenotypicFeature denotes UUO D014517
T8 679-687 DiseaseOrPhenotypicFeature denotes fibrosis D005355
T9 860-872 DiseaseOrPhenotypicFeature denotes inflammatory DISEASE
T10 920-932 DiseaseOrPhenotypicFeature denotes renal damage DISEASE
T11 937-945 DiseaseOrPhenotypicFeature denotes fibrosis D005355
T12 1082-1085 DiseaseOrPhenotypicFeature denotes RIF DISEASE
T13 1151-1157 DiseaseOrPhenotypicFeature denotes injury D014947
T14 1653-1665 DiseaseOrPhenotypicFeature denotes inflammatory DISEASE
T15 1766-1774 DiseaseOrPhenotypicFeature denotes fibrosis D005355
T16 2163-2175 DiseaseOrPhenotypicFeature denotes inflammatory DISEASE
T17 2366-2374 DiseaseOrPhenotypicFeature denotes fibrosis D005355

LitCoin_CellLine

Id Subject Object Predicate Lexical cue cellosaurus_accession_id
T1 791-795 CellLine denotes HK-2 AddedByYayamamo
T2 2085-2089 CellLine denotes HK-2 AddedByYayamamo

LitCoin-MONDO_bioort2019

Id Subject Object Predicate Lexical cue #label
T1 43-51 DiseaseOrPhenotypicFeature denotes Fibrosis D005355
T2 316-324 DiseaseOrPhenotypicFeature denotes fibrosis D005355
T3 461-469 DiseaseOrPhenotypicFeature denotes fibrosis D005355
T4 471-474 DiseaseOrPhenotypicFeature denotes RIF DISEASE
T5 601-621 DiseaseOrPhenotypicFeature denotes ureteric obstruction D014517
T6 623-626 DiseaseOrPhenotypicFeature denotes UUO D014517
T7 679-687 DiseaseOrPhenotypicFeature denotes fibrosis D005355
T8 920-932 DiseaseOrPhenotypicFeature denotes renal damage DISEASE
T9 937-945 DiseaseOrPhenotypicFeature denotes fibrosis D005355
T10 1082-1085 DiseaseOrPhenotypicFeature denotes RIF DISEASE
T11 1766-1774 DiseaseOrPhenotypicFeature denotes fibrosis D005355
T12 2366-2374 DiseaseOrPhenotypicFeature denotes fibrosis D005355

LitCoin-NCBITaxon-2

Id Subject Object Predicate Lexical cue
T1 174-188 OrganismTaxon denotes Rhodiola rosea
T2 655-659 OrganismTaxon denotes mice
T3 751-756 OrganismTaxon denotes human
T4 2067-2072 OrganismTaxon denotes mouse

LitCoin-Chemical-MeSH-CHEBI

Id Subject Object Predicate Lexical cue ID:
T1 0-11 ChemicalEntity denotes Salidroside http://purl.obolibrary.org/obo/CHEBI_9009
T2 110-121 ChemicalEntity denotes Salidroside http://purl.obolibrary.org/obo/CHEBI_9009
T3 123-126 ChemicalEntity denotes Sal http://purl.obolibrary.org/obo/CHEBI_9009
T4 303-306 ChemicalEntity denotes Sal http://purl.obolibrary.org/obo/CHEBI_9009
T5 430-433 ChemicalEntity denotes Sal http://purl.obolibrary.org/obo/CHEBI_9009
T6 631-641 ChemicalEntity denotes folic acid D005492|http://purl.obolibrary.org/obo/CHEBI_27470
T8 643-645 ChemicalEntity denotes FA D005492
T9 1070-1073 ChemicalEntity denotes Sal http://purl.obolibrary.org/obo/CHEBI_9009
T10 1124-1127 ChemicalEntity denotes Sal http://purl.obolibrary.org/obo/CHEBI_9009
T11 1229-1237 ChemicalEntity denotes collagen http://purl.obolibrary.org/obo/CHEBI_3815
T12 1244-1252 ChemicalEntity denotes collagen http://purl.obolibrary.org/obo/CHEBI_3815
T13 1270-1273 ChemicalEntity denotes Sal http://purl.obolibrary.org/obo/CHEBI_9009
T14 1498-1501 ChemicalEntity denotes Sal http://purl.obolibrary.org/obo/CHEBI_9009
T15 1535-1554 ChemicalEntity denotes biochemical markers D015415
T16 1562-1572 ChemicalEntity denotes creatinine D003404|http://purl.obolibrary.org/obo/CHEBI_16737
T18 1585-1589 ChemicalEntity denotes urea D014508|http://purl.obolibrary.org/obo/CHEBI_16199
T20 1590-1598 ChemicalEntity denotes nitrogen D009584|http://purl.obolibrary.org/obo/CHEBI_25555
T22 1609-1618 ChemicalEntity denotes uric acid D014527|http://purl.obolibrary.org/obo/CHEBI_27226
T24 1740-1743 ChemicalEntity denotes Sal http://purl.obolibrary.org/obo/CHEBI_9009
T25 1928-1931 ChemicalEntity denotes Sal http://purl.obolibrary.org/obo/CHEBI_9009
T26 2110-2113 ChemicalEntity denotes Sal http://purl.obolibrary.org/obo/CHEBI_9009
T27 2306-2309 ChemicalEntity denotes Sal http://purl.obolibrary.org/obo/CHEBI_9009

LitCoin-training-merged

Id Subject Object Predicate Lexical cue #label ID: cellosaurus_accession_id
T2 2085-2089 CellLine denotes HK-2 AddedByYayamamo
T1 791-795 CellLine denotes HK-2 AddedByYayamamo
T27 2306-2309 ChemicalEntity denotes Sal http://purl.obolibrary.org/obo/CHEBI_9009
T26 2110-2113 ChemicalEntity denotes Sal http://purl.obolibrary.org/obo/CHEBI_9009
T25 1928-1931 ChemicalEntity denotes Sal http://purl.obolibrary.org/obo/CHEBI_9009
T24 1740-1743 ChemicalEntity denotes Sal http://purl.obolibrary.org/obo/CHEBI_9009
T22 1609-1618 ChemicalEntity denotes uric acid http://purl.obolibrary.org/obo/CHEBI_27226|D014527
T20 1590-1598 ChemicalEntity denotes nitrogen http://purl.obolibrary.org/obo/CHEBI_25555|D009584
T18 1585-1589 ChemicalEntity denotes urea http://purl.obolibrary.org/obo/CHEBI_16199|D014508
T16 1562-1572 ChemicalEntity denotes creatinine http://purl.obolibrary.org/obo/CHEBI_16737|D003404
T15 1535-1554 ChemicalEntity denotes biochemical markers D015415
T14 1498-1501 ChemicalEntity denotes Sal http://purl.obolibrary.org/obo/CHEBI_9009
T13 1270-1273 ChemicalEntity denotes Sal http://purl.obolibrary.org/obo/CHEBI_9009
T12 1244-1252 ChemicalEntity denotes collagen http://purl.obolibrary.org/obo/CHEBI_3815
T11 1229-1237 ChemicalEntity denotes collagen http://purl.obolibrary.org/obo/CHEBI_3815
T10 1124-1127 ChemicalEntity denotes Sal http://purl.obolibrary.org/obo/CHEBI_9009
T9 1070-1073 ChemicalEntity denotes Sal http://purl.obolibrary.org/obo/CHEBI_9009
T8 643-645 ChemicalEntity denotes FA D005492
T6 631-641 ChemicalEntity denotes folic acid http://purl.obolibrary.org/obo/CHEBI_27470|D005492
T5 430-433 ChemicalEntity denotes Sal http://purl.obolibrary.org/obo/CHEBI_9009
T4 303-306 ChemicalEntity denotes Sal http://purl.obolibrary.org/obo/CHEBI_9009
T3 123-126 ChemicalEntity denotes Sal http://purl.obolibrary.org/obo/CHEBI_9009
T54726 110-121 ChemicalEntity denotes Salidroside http://purl.obolibrary.org/obo/CHEBI_9009
T22323 0-11 ChemicalEntity denotes Salidroside http://purl.obolibrary.org/obo/CHEBI_9009
T75005 2218-2222 GeneOrGeneProduct denotes MAPK
T19 2203-2207 GeneOrGeneProduct denotes TLR4
T70882 1879-1883 GeneOrGeneProduct denotes MAPK
T17 1844-1869 GeneOrGeneProduct denotes mitogen-activated protein
T20052 1818-1822 GeneOrGeneProduct denotes TLR4
T50299 1684-1688 GeneOrGeneProduct denotes IL-6
T40576 1677-1681 GeneOrGeneProduct denotes IL-1
T86715 1609-1613 GeneOrGeneProduct denotes uric
T74657 1472-1482 GeneOrGeneProduct denotes E-cadherin
T15367 1429-1433 GeneOrGeneProduct denotes slug
T55399 1422-1427 GeneOrGeneProduct denotes snail
T34546 1414-1417 GeneOrGeneProduct denotes TGF
T5269 1404-1412 GeneOrGeneProduct denotes vimentin
T7 1399-1402 GeneOrGeneProduct denotes SMA
T76765 1244-1252 GeneOrGeneProduct denotes collagen
T44675 1229-1237 GeneOrGeneProduct denotes collagen
T49127 732-735 GeneOrGeneProduct denotes TGF
T2676 717-730 GeneOrGeneProduct denotes growth factor
T13639 85-89 GeneOrGeneProduct denotes MAPK
T95036 70-74 GeneOrGeneProduct denotes TLR4
T99492 2366-2374 DiseaseOrPhenotypicFeature denotes fibrosis D005355
T49249 1766-1774 DiseaseOrPhenotypicFeature denotes fibrosis D005355
T32591 1082-1085 DiseaseOrPhenotypicFeature denotes RIF DISEASE
T96043 937-945 DiseaseOrPhenotypicFeature denotes fibrosis D005355
T80306 920-932 DiseaseOrPhenotypicFeature denotes renal damage DISEASE
T59604 679-687 DiseaseOrPhenotypicFeature denotes fibrosis D005355
T66543 623-626 DiseaseOrPhenotypicFeature denotes UUO D014517
T20591 601-621 DiseaseOrPhenotypicFeature denotes ureteric obstruction D014517
T31340 471-474 DiseaseOrPhenotypicFeature denotes RIF DISEASE
T16261 461-469 DiseaseOrPhenotypicFeature denotes fibrosis D005355
T20737 316-324 DiseaseOrPhenotypicFeature denotes fibrosis D005355
T29477 43-51 DiseaseOrPhenotypicFeature denotes Fibrosis D005355
T52574 2067-2072 OrganismTaxon denotes mouse
T77668 751-756 OrganismTaxon denotes human
T93724 655-659 OrganismTaxon denotes mice
T38027 174-188 OrganismTaxon denotes Rhodiola rosea