PubMed:30831029
Annnotations
GlyCosmos600-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 57-71 | http://purl.obolibrary.org/obo/CL_0000746 | denotes | Cardiomyocytes |
T2 | 490-504 | http://purl.obolibrary.org/obo/CL_0000746 | denotes | cardiomyocytes |
T3 | 583-589 | http://purl.obolibrary.org/obo/CLO_0001689 | denotes | a HL-1 |
T4 | 590-595 | http://purl.obolibrary.org/obo/CLO_0007836 | denotes | mouse |
T5 | 596-609 | http://purl.obolibrary.org/obo/CL_0000746 | denotes | cardiomyocyte |
T6 | 610-614 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T7 | 941-951 | http://purl.obolibrary.org/obo/GO_0030017 | denotes | sarcomeric |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
TextSentencer_T1 | 0-72 | Sentence | denotes | Proteomic Identification of Protein Glutathionylation in Cardiomyocytes. |
TextSentencer_T2 | 73-237 | Sentence | denotes | Reactive oxygen species (ROS) are important signaling molecules, but their overproduction is associated with many cardiovascular diseases, including cardiomyopathy. |
TextSentencer_T3 | 238-391 | Sentence | denotes | ROS induce various oxidative modifications, among which glutathionylation is one of the significant protein oxidations that occur under oxidative stress. |
TextSentencer_T4 | 392-522 | Sentence | denotes | Despite previous efforts, direct and site-specific identification of glutathionylated proteins in cardiomyocytes has been limited. |
TextSentencer_T5 | 523-778 | Sentence | denotes | In this report, we used a clickable glutathione approach in a HL-1 mouse cardiomyocyte cell line under exposure to hydrogen peroxide, finding 1763 glutathionylated peptides with specific Cys modification sites, which include many muscle-specific proteins. |
TextSentencer_T6 | 779-1043 | Sentence | denotes | Bioinformatic and cluster analyses found 125 glutathionylated proteins, whose mutations or dysfunctions are associated with cardiomyopathy, many of which include sarcomeric structural and contractile proteins, chaperone, and other signaling or regulatory proteins. |
TextSentencer_T7 | 1044-1244 | Sentence | denotes | We further provide functional implication of glutathionylation for several identified proteins, including CSRP3/MLP and complex I, II, and III, by analyzing glutathionylated sites in their structures. |
TextSentencer_T8 | 1245-1444 | Sentence | denotes | Our report establishes a chemoselective method for direct identification of glutathionylated proteins and provides potential target proteins whose glutathionylation may contribute to muscle diseases. |
T1 | 0-72 | Sentence | denotes | Proteomic Identification of Protein Glutathionylation in Cardiomyocytes. |
T2 | 73-237 | Sentence | denotes | Reactive oxygen species (ROS) are important signaling molecules, but their overproduction is associated with many cardiovascular diseases, including cardiomyopathy. |
T3 | 238-391 | Sentence | denotes | ROS induce various oxidative modifications, among which glutathionylation is one of the significant protein oxidations that occur under oxidative stress. |
T4 | 392-522 | Sentence | denotes | Despite previous efforts, direct and site-specific identification of glutathionylated proteins in cardiomyocytes has been limited. |
T5 | 523-778 | Sentence | denotes | In this report, we used a clickable glutathione approach in a HL-1 mouse cardiomyocyte cell line under exposure to hydrogen peroxide, finding 1763 glutathionylated peptides with specific Cys modification sites, which include many muscle-specific proteins. |
T6 | 779-1043 | Sentence | denotes | Bioinformatic and cluster analyses found 125 glutathionylated proteins, whose mutations or dysfunctions are associated with cardiomyopathy, many of which include sarcomeric structural and contractile proteins, chaperone, and other signaling or regulatory proteins. |
T7 | 1044-1244 | Sentence | denotes | We further provide functional implication of glutathionylation for several identified proteins, including CSRP3/MLP and complex I, II, and III, by analyzing glutathionylated sites in their structures. |
T8 | 1245-1444 | Sentence | denotes | Our report establishes a chemoselective method for direct identification of glutathionylated proteins and provides potential target proteins whose glutathionylation may contribute to muscle diseases. |
Glycosmos6-MAT
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 753-759 | http://purl.obolibrary.org/obo/MAT_0000025 | denotes | muscle |
T2 | 1428-1434 | http://purl.obolibrary.org/obo/MAT_0000025 | denotes | muscle |
GlyCosmos600-FMA
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T1 | 28-35 | Body_part | denotes | Protein | http://purl.org/sig/ont/fma/fma67257 |
T2 | 57-71 | Body_part | denotes | Cardiomyocytes | http://purl.org/sig/ont/fma/fma14067 |
T3 | 338-345 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T4 | 478-486 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
T5 | 490-504 | Body_part | denotes | cardiomyocytes | http://purl.org/sig/ont/fma/fma14067 |
T6 | 596-609 | Body_part | denotes | cardiomyocyte | http://purl.org/sig/ont/fma/fma14067 |
T7 | 610-614 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T8 | 753-759 | Body_part | denotes | muscle | http://purl.org/sig/ont/fma/fma32558 |
T9 | 769-777 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
T10 | 841-849 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
T11 | 941-951 | Body_part | denotes | sarcomeric | http://purl.org/sig/ont/fma/fma67895 |
T12 | 979-987 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
T13 | 1034-1042 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
T14 | 1130-1138 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
T15 | 1338-1346 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
T16 | 1377-1385 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
T17 | 1428-1434 | Body_part | denotes | muscle | http://purl.org/sig/ont/fma/fma32558 |
GlyCosmos600-MAT
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
PD-MAT-B_T1 | 753-759 | http://purl.obolibrary.org/obo/MAT_0000025 | denotes | muscle |
PD-MAT-B_T2 | 1428-1434 | http://purl.obolibrary.org/obo/MAT_0000025 | denotes | muscle |
GlyCosmos600-GlycoProteins
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
PD-GlycoProteins-B_T1 | 585-587 | http://purl.uniprot.org/uniprot/P35914 | denotes | HL |
PD-GlycoProteins-B_T2 | 585-587 | http://purl.uniprot.org/uniprot/O81027 | denotes | HL |
pubmed-enju-pas
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
EnjuParser_T0 | 0-9 | JJ | denotes | Proteomic |
EnjuParser_T1 | 10-24 | NN | denotes | Identification |
EnjuParser_T2 | 25-27 | IN | denotes | of |
EnjuParser_T3 | 28-35 | NN | denotes | Protein |
EnjuParser_T4 | 36-53 | NN | denotes | Glutathionylation |
EnjuParser_T5 | 54-56 | IN | denotes | in |
EnjuParser_T6 | 57-71 | NNS | denotes | Cardiomyocytes |
EnjuParser_T7 | 73-81 | JJ | denotes | Reactive |
EnjuParser_T8 | 82-88 | NN | denotes | oxygen |
EnjuParser_T9 | 89-96 | NNS | denotes | species |
EnjuParser_T10 | 97-98 | -LRB- | denotes | ( |
EnjuParser_T11 | 98-101 | NN | denotes | ROS |
EnjuParser_T12 | 101-102 | -RRB- | denotes | ) |
EnjuParser_T13 | 103-106 | VBP | denotes | are |
EnjuParser_T14 | 107-116 | JJ | denotes | important |
EnjuParser_T15 | 117-126 | VBG | denotes | signaling |
EnjuParser_T16 | 127-136 | NNS | denotes | molecules |
EnjuParser_T17 | 136-137 | -COMMA- | denotes | , |
EnjuParser_T18 | 138-141 | CC | denotes | but |
EnjuParser_T19 | 142-147 | PRP-DOLLAR- | denotes | their |
EnjuParser_T20 | 148-162 | NN | denotes | overproduction |
EnjuParser_T21 | 163-165 | VBZ | denotes | is |
EnjuParser_T22 | 166-176 | VBN | denotes | associated |
EnjuParser_T23 | 177-181 | IN | denotes | with |
EnjuParser_T24 | 182-186 | JJ | denotes | many |
EnjuParser_T25 | 187-201 | JJ | denotes | cardiovascular |
EnjuParser_T26 | 202-210 | NNS | denotes | diseases |
EnjuParser_T27 | 210-211 | -COMMA- | denotes | , |
EnjuParser_T28 | 212-221 | VBG | denotes | including |
EnjuParser_T29 | 222-236 | NN | denotes | cardiomyopathy |
EnjuParser_T30 | 238-241 | NNS | denotes | ROS |
EnjuParser_T31 | 242-248 | VBP | denotes | induce |
EnjuParser_T32 | 249-256 | JJ | denotes | various |
EnjuParser_T33 | 257-266 | JJ | denotes | oxidative |
EnjuParser_T34 | 267-280 | NNS | denotes | modifications |
EnjuParser_T35 | 280-281 | -COMMA- | denotes | , |
EnjuParser_T36 | 282-287 | IN | denotes | among |
EnjuParser_T37 | 288-293 | WDT | denotes | which |
EnjuParser_T38 | 294-311 | NN | denotes | glutathionylation |
EnjuParser_T39 | 312-314 | VBZ | denotes | is |
EnjuParser_T40 | 315-318 | CD | denotes | one |
EnjuParser_T41 | 319-321 | IN | denotes | of |
EnjuParser_T42 | 322-325 | DT | denotes | the |
EnjuParser_T43 | 326-337 | JJ | denotes | significant |
EnjuParser_T44 | 338-345 | NN | denotes | protein |
EnjuParser_T45 | 346-356 | NNS | denotes | oxidations |
EnjuParser_T46 | 357-361 | WDT | denotes | that |
EnjuParser_T47 | 362-367 | VBP | denotes | occur |
EnjuParser_T48 | 368-373 | IN | denotes | under |
EnjuParser_T49 | 374-383 | JJ | denotes | oxidative |
EnjuParser_T50 | 384-390 | NN | denotes | stress |
EnjuParser_T51 | 392-399 | IN | denotes | Despite |
EnjuParser_T52 | 400-408 | JJ | denotes | previous |
EnjuParser_T53 | 409-416 | NNS | denotes | efforts |
EnjuParser_T54 | 416-417 | -COMMA- | denotes | , |
EnjuParser_T55 | 418-424 | JJ | denotes | direct |
EnjuParser_T56 | 425-428 | CC | denotes | and |
EnjuParser_T57 | 429-442 | JJ | denotes | site-specific |
EnjuParser_T58 | 443-457 | NN | denotes | identification |
EnjuParser_T59 | 458-460 | IN | denotes | of |
EnjuParser_T60 | 461-477 | VBN | denotes | glutathionylated |
EnjuParser_T61 | 478-486 | NNS | denotes | proteins |
EnjuParser_T62 | 487-489 | IN | denotes | in |
EnjuParser_T63 | 490-504 | NNS | denotes | cardiomyocytes |
EnjuParser_T64 | 505-508 | VBZ | denotes | has |
EnjuParser_T65 | 509-513 | VBN | denotes | been |
EnjuParser_T66 | 514-521 | VBN | denotes | limited |
EnjuParser_T67 | 523-525 | IN | denotes | In |
EnjuParser_T68 | 526-530 | DT | denotes | this |
EnjuParser_T69 | 531-537 | NN | denotes | report |
EnjuParser_T70 | 537-538 | -COMMA- | denotes | , |
EnjuParser_T71 | 539-541 | PRP | denotes | we |
EnjuParser_T72 | 542-546 | VBD | denotes | used |
EnjuParser_T73 | 547-548 | DT | denotes | a |
EnjuParser_T74 | 549-558 | JJ | denotes | clickable |
EnjuParser_T75 | 559-570 | NN | denotes | glutathione |
EnjuParser_T76 | 571-579 | NN | denotes | approach |
EnjuParser_T77 | 580-582 | IN | denotes | in |
EnjuParser_T78 | 583-584 | DT | denotes | a |
EnjuParser_T79 | 585-589 | NN | denotes | HL-1 |
EnjuParser_T80 | 590-595 | NN | denotes | mouse |
EnjuParser_T81 | 596-609 | NN | denotes | cardiomyocyte |
EnjuParser_T82 | 610-614 | NN | denotes | cell |
EnjuParser_T83 | 615-619 | NN | denotes | line |
EnjuParser_T84 | 620-625 | IN | denotes | under |
EnjuParser_T85 | 626-634 | NN | denotes | exposure |
EnjuParser_T86 | 635-637 | TO | denotes | to |
EnjuParser_T87 | 638-646 | NN | denotes | hydrogen |
EnjuParser_T88 | 647-655 | NN | denotes | peroxide |
EnjuParser_T89 | 655-656 | -COMMA- | denotes | , |
EnjuParser_T90 | 657-664 | VBG | denotes | finding |
EnjuParser_T91 | 665-669 | CD | denotes | 1763 |
EnjuParser_T92 | 670-686 | VBN | denotes | glutathionylated |
EnjuParser_T93 | 687-695 | NNS | denotes | peptides |
EnjuParser_T94 | 696-700 | IN | denotes | with |
EnjuParser_T95 | 701-709 | JJ | denotes | specific |
EnjuParser_T96 | 710-713 | NN | denotes | Cys |
EnjuParser_T97 | 714-726 | NN | denotes | modification |
EnjuParser_T98 | 727-732 | NNS | denotes | sites |
EnjuParser_T99 | 732-733 | -COMMA- | denotes | , |
EnjuParser_T100 | 734-739 | WDT | denotes | which |
EnjuParser_T101 | 740-747 | VBP | denotes | include |
EnjuParser_T102 | 748-752 | JJ | denotes | many |
EnjuParser_T103 | 753-768 | JJ | denotes | muscle-specific |
EnjuParser_T104 | 769-777 | NNS | denotes | proteins |
EnjuParser_T105 | 779-792 | JJ | denotes | Bioinformatic |
EnjuParser_T106 | 793-796 | CC | denotes | and |
EnjuParser_T107 | 797-804 | NN | denotes | cluster |
EnjuParser_T108 | 805-813 | NNS | denotes | analyses |
EnjuParser_T109 | 814-819 | VBD | denotes | found |
EnjuParser_T110 | 820-823 | CD | denotes | 125 |
EnjuParser_T111 | 824-840 | VBN | denotes | glutathionylated |
EnjuParser_T112 | 841-849 | NNS | denotes | proteins |
EnjuParser_T113 | 849-850 | -COMMA- | denotes | , |
EnjuParser_T114 | 851-856 | WP-DOLLAR- | denotes | whose |
EnjuParser_T115 | 857-866 | NNS | denotes | mutations |
EnjuParser_T116 | 867-869 | CC | denotes | or |
EnjuParser_T117 | 870-882 | NNS | denotes | dysfunctions |
EnjuParser_T118 | 883-886 | VBP | denotes | are |
EnjuParser_T119 | 887-897 | VBN | denotes | associated |
EnjuParser_T120 | 898-902 | IN | denotes | with |
EnjuParser_T121 | 903-917 | NN | denotes | cardiomyopathy |
EnjuParser_T122 | 917-918 | -COMMA- | denotes | , |
EnjuParser_T123 | 919-923 | JJ | denotes | many |
EnjuParser_T124 | 924-926 | IN | denotes | of |
EnjuParser_T125 | 927-932 | WDT | denotes | which |
EnjuParser_T126 | 933-940 | VBP | denotes | include |
EnjuParser_T127 | 941-951 | JJ | denotes | sarcomeric |
EnjuParser_T128 | 952-962 | JJ | denotes | structural |
EnjuParser_T129 | 963-966 | CC | denotes | and |
EnjuParser_T130 | 967-978 | JJ | denotes | contractile |
EnjuParser_T131 | 979-987 | NNS | denotes | proteins |
EnjuParser_T132 | 987-988 | -COMMA- | denotes | , |
EnjuParser_T133 | 989-998 | NN | denotes | chaperone |
EnjuParser_T134 | 998-999 | -COMMA- | denotes | , |
EnjuParser_T135 | 1000-1003 | CC | denotes | and |
EnjuParser_T136 | 1004-1009 | JJ | denotes | other |
EnjuParser_T137 | 1010-1019 | NN | denotes | signaling |
EnjuParser_T138 | 1020-1022 | CC | denotes | or |
EnjuParser_T139 | 1023-1033 | JJ | denotes | regulatory |
EnjuParser_T140 | 1034-1042 | NNS | denotes | proteins |
EnjuParser_T141 | 1044-1046 | PRP | denotes | We |
EnjuParser_T142 | 1047-1054 | RB | denotes | further |
EnjuParser_T143 | 1055-1062 | VBP | denotes | provide |
EnjuParser_T144 | 1063-1073 | JJ | denotes | functional |
EnjuParser_T145 | 1074-1085 | NN | denotes | implication |
EnjuParser_T146 | 1086-1088 | IN | denotes | of |
EnjuParser_T147 | 1089-1106 | NN | denotes | glutathionylation |
EnjuParser_T148 | 1107-1110 | IN | denotes | for |
EnjuParser_T149 | 1111-1118 | JJ | denotes | several |
EnjuParser_T150 | 1119-1129 | VBN | denotes | identified |
EnjuParser_T151 | 1130-1138 | NNS | denotes | proteins |
EnjuParser_T152 | 1138-1139 | -COMMA- | denotes | , |
EnjuParser_T153 | 1140-1149 | VBG | denotes | including |
EnjuParser_T154 | 1150-1159 | NN | denotes | CSRP3/MLP |
EnjuParser_T155 | 1160-1163 | CC | denotes | and |
EnjuParser_T156 | 1164-1171 | NN | denotes | complex |
EnjuParser_T157 | 1172-1173 | CD | denotes | I |
EnjuParser_T158 | 1173-1174 | -COMMA- | denotes | , |
EnjuParser_T159 | 1175-1177 | CD | denotes | II |
EnjuParser_T160 | 1177-1178 | -COMMA- | denotes | , |
EnjuParser_T161 | 1179-1182 | CC | denotes | and |
EnjuParser_T162 | 1183-1186 | CD | denotes | III |
EnjuParser_T163 | 1186-1187 | -COMMA- | denotes | , |
EnjuParser_T164 | 1188-1190 | IN | denotes | by |
EnjuParser_T165 | 1191-1200 | VBG | denotes | analyzing |
EnjuParser_T166 | 1201-1217 | VBN | denotes | glutathionylated |
EnjuParser_T167 | 1218-1223 | NNS | denotes | sites |
EnjuParser_T168 | 1224-1226 | IN | denotes | in |
EnjuParser_T169 | 1227-1232 | PRP-DOLLAR- | denotes | their |
EnjuParser_T170 | 1233-1243 | NNS | denotes | structures |
EnjuParser_T171 | 1245-1248 | PRP-DOLLAR- | denotes | Our |
EnjuParser_T172 | 1249-1255 | NN | denotes | report |
EnjuParser_T173 | 1256-1267 | VBZ | denotes | establishes |
EnjuParser_T174 | 1268-1269 | DT | denotes | a |
EnjuParser_T175 | 1270-1284 | JJ | denotes | chemoselective |
EnjuParser_T176 | 1285-1291 | NN | denotes | method |
EnjuParser_T177 | 1292-1295 | IN | denotes | for |
EnjuParser_T178 | 1296-1302 | JJ | denotes | direct |
EnjuParser_T179 | 1303-1317 | NN | denotes | identification |
EnjuParser_T180 | 1318-1320 | IN | denotes | of |
EnjuParser_T181 | 1321-1337 | VBN | denotes | glutathionylated |
EnjuParser_T182 | 1338-1346 | NNS | denotes | proteins |
EnjuParser_T183 | 1347-1350 | CC | denotes | and |
EnjuParser_T184 | 1351-1359 | VBZ | denotes | provides |
EnjuParser_T185 | 1360-1369 | JJ | denotes | potential |
EnjuParser_T186 | 1370-1376 | NN | denotes | target |
EnjuParser_T187 | 1377-1385 | NNS | denotes | proteins |
EnjuParser_T188 | 1386-1391 | WP-DOLLAR- | denotes | whose |
EnjuParser_T189 | 1392-1409 | NN | denotes | glutathionylation |
EnjuParser_T190 | 1410-1413 | MD | denotes | may |
EnjuParser_T191 | 1414-1424 | VB | denotes | contribute |
EnjuParser_T192 | 1425-1427 | TO | denotes | to |
EnjuParser_T193 | 1428-1434 | NN | denotes | muscle |
EnjuParser_T194 | 1435-1443 | NNS | denotes | diseases |
EnjuParser_R0 | EnjuParser_T1 | EnjuParser_T0 | arg1Of | Identification,Proteomic |
EnjuParser_R1 | EnjuParser_T1 | EnjuParser_T2 | arg1Of | Identification,of |
EnjuParser_R2 | EnjuParser_T4 | EnjuParser_T2 | arg2Of | Glutathionylation,of |
EnjuParser_R3 | EnjuParser_T4 | EnjuParser_T3 | arg1Of | Glutathionylation,Protein |
EnjuParser_R4 | EnjuParser_T4 | EnjuParser_T5 | arg1Of | Glutathionylation,in |
EnjuParser_R5 | EnjuParser_T6 | EnjuParser_T5 | arg2Of | Cardiomyocytes,in |
EnjuParser_R6 | EnjuParser_T9 | EnjuParser_T7 | arg1Of | species,Reactive |
EnjuParser_R7 | EnjuParser_T9 | EnjuParser_T8 | arg1Of | species,oxygen |
EnjuParser_R8 | EnjuParser_T9 | EnjuParser_T10 | arg1Of | species,( |
EnjuParser_R9 | EnjuParser_T11 | EnjuParser_T10 | arg2Of | ROS,( |
EnjuParser_R10 | EnjuParser_T12 | EnjuParser_T10 | arg3Of | ),( |
EnjuParser_R11 | EnjuParser_T9 | EnjuParser_T13 | arg1Of | species,are |
EnjuParser_R12 | EnjuParser_T16 | EnjuParser_T13 | arg2Of | molecules,are |
EnjuParser_R13 | EnjuParser_T16 | EnjuParser_T14 | arg1Of | molecules,important |
EnjuParser_R14 | EnjuParser_T16 | EnjuParser_T15 | arg1Of | molecules,signaling |
EnjuParser_R15 | EnjuParser_T18 | EnjuParser_T17 | arg1Of | but,"," |
EnjuParser_R16 | EnjuParser_T13 | EnjuParser_T18 | arg1Of | are,but |
EnjuParser_R17 | EnjuParser_T22 | EnjuParser_T18 | arg2Of | associated,but |
EnjuParser_R18 | EnjuParser_T20 | EnjuParser_T19 | arg1Of | overproduction,their |
EnjuParser_R19 | EnjuParser_T20 | EnjuParser_T21 | arg1Of | overproduction,is |
EnjuParser_R20 | EnjuParser_T22 | EnjuParser_T21 | arg2Of | associated,is |
EnjuParser_R21 | EnjuParser_T20 | EnjuParser_T22 | arg2Of | overproduction,associated |
EnjuParser_R22 | EnjuParser_T22 | EnjuParser_T23 | arg1Of | associated,with |
EnjuParser_R23 | EnjuParser_T26 | EnjuParser_T23 | arg2Of | diseases,with |
EnjuParser_R24 | EnjuParser_T26 | EnjuParser_T24 | arg1Of | diseases,many |
EnjuParser_R25 | EnjuParser_T26 | EnjuParser_T25 | arg1Of | diseases,cardiovascular |
EnjuParser_R26 | EnjuParser_T26 | EnjuParser_T27 | arg1Of | diseases,"," |
EnjuParser_R27 | EnjuParser_T26 | EnjuParser_T28 | arg1Of | diseases,including |
EnjuParser_R28 | EnjuParser_T29 | EnjuParser_T28 | arg2Of | cardiomyopathy,including |
EnjuParser_R29 | EnjuParser_T30 | EnjuParser_T31 | arg1Of | ROS,induce |
EnjuParser_R30 | EnjuParser_T34 | EnjuParser_T31 | arg2Of | modifications,induce |
EnjuParser_R31 | EnjuParser_T34 | EnjuParser_T32 | arg1Of | modifications,various |
EnjuParser_R32 | EnjuParser_T34 | EnjuParser_T33 | arg1Of | modifications,oxidative |
EnjuParser_R33 | EnjuParser_T34 | EnjuParser_T35 | arg1Of | modifications,"," |
EnjuParser_R34 | EnjuParser_T39 | EnjuParser_T36 | arg1Of | is,among |
EnjuParser_R35 | EnjuParser_T34 | EnjuParser_T36 | arg2Of | modifications,among |
EnjuParser_R36 | EnjuParser_T34 | EnjuParser_T37 | arg1Of | modifications,which |
EnjuParser_R37 | EnjuParser_T38 | EnjuParser_T39 | arg1Of | glutathionylation,is |
EnjuParser_R38 | EnjuParser_T40 | EnjuParser_T39 | arg2Of | one,is |
EnjuParser_R39 | EnjuParser_T40 | EnjuParser_T41 | arg1Of | one,of |
EnjuParser_R40 | EnjuParser_T45 | EnjuParser_T41 | arg2Of | oxidations,of |
EnjuParser_R41 | EnjuParser_T45 | EnjuParser_T42 | arg1Of | oxidations,the |
EnjuParser_R42 | EnjuParser_T45 | EnjuParser_T43 | arg1Of | oxidations,significant |
EnjuParser_R43 | EnjuParser_T45 | EnjuParser_T44 | arg1Of | oxidations,protein |
EnjuParser_R44 | EnjuParser_T45 | EnjuParser_T46 | arg1Of | oxidations,that |
EnjuParser_R45 | EnjuParser_T45 | EnjuParser_T47 | arg1Of | oxidations,occur |
EnjuParser_R46 | EnjuParser_T47 | EnjuParser_T48 | arg1Of | occur,under |
EnjuParser_R47 | EnjuParser_T50 | EnjuParser_T48 | arg2Of | stress,under |
EnjuParser_R48 | EnjuParser_T50 | EnjuParser_T49 | arg1Of | stress,oxidative |
EnjuParser_R49 | EnjuParser_T66 | EnjuParser_T51 | arg1Of | limited,Despite |
EnjuParser_R50 | EnjuParser_T53 | EnjuParser_T51 | arg2Of | efforts,Despite |
EnjuParser_R51 | EnjuParser_T53 | EnjuParser_T52 | arg1Of | efforts,previous |
EnjuParser_R52 | EnjuParser_T66 | EnjuParser_T54 | arg1Of | limited,"," |
EnjuParser_R53 | EnjuParser_T58 | EnjuParser_T55 | arg1Of | identification,direct |
EnjuParser_R54 | EnjuParser_T55 | EnjuParser_T56 | arg1Of | direct,and |
EnjuParser_R55 | EnjuParser_T57 | EnjuParser_T56 | arg2Of | site-specific,and |
EnjuParser_R56 | EnjuParser_T58 | EnjuParser_T57 | arg1Of | identification,site-specific |
EnjuParser_R57 | EnjuParser_T58 | EnjuParser_T59 | arg1Of | identification,of |
EnjuParser_R58 | EnjuParser_T61 | EnjuParser_T59 | arg2Of | proteins,of |
EnjuParser_R59 | EnjuParser_T61 | EnjuParser_T60 | arg2Of | proteins,glutathionylated |
EnjuParser_R60 | EnjuParser_T61 | EnjuParser_T62 | arg1Of | proteins,in |
EnjuParser_R61 | EnjuParser_T63 | EnjuParser_T62 | arg2Of | cardiomyocytes,in |
EnjuParser_R62 | EnjuParser_T58 | EnjuParser_T64 | arg1Of | identification,has |
EnjuParser_R63 | EnjuParser_T66 | EnjuParser_T64 | arg2Of | limited,has |
EnjuParser_R64 | EnjuParser_T58 | EnjuParser_T65 | arg1Of | identification,been |
EnjuParser_R65 | EnjuParser_T66 | EnjuParser_T65 | arg2Of | limited,been |
EnjuParser_R66 | EnjuParser_T58 | EnjuParser_T66 | arg2Of | identification,limited |
EnjuParser_R67 | EnjuParser_T72 | EnjuParser_T67 | arg1Of | used,In |
EnjuParser_R68 | EnjuParser_T69 | EnjuParser_T67 | arg2Of | report,In |
EnjuParser_R69 | EnjuParser_T69 | EnjuParser_T68 | arg1Of | report,this |
EnjuParser_R70 | EnjuParser_T72 | EnjuParser_T70 | arg1Of | used,"," |
EnjuParser_R71 | EnjuParser_T71 | EnjuParser_T72 | arg1Of | we,used |
EnjuParser_R72 | EnjuParser_T76 | EnjuParser_T72 | arg2Of | approach,used |
EnjuParser_R73 | EnjuParser_T76 | EnjuParser_T73 | arg1Of | approach,a |
EnjuParser_R74 | EnjuParser_T76 | EnjuParser_T74 | arg1Of | approach,clickable |
EnjuParser_R75 | EnjuParser_T76 | EnjuParser_T75 | arg1Of | approach,glutathione |
EnjuParser_R76 | EnjuParser_T76 | EnjuParser_T77 | arg1Of | approach,in |
EnjuParser_R77 | EnjuParser_T83 | EnjuParser_T77 | arg2Of | line,in |
EnjuParser_R78 | EnjuParser_T83 | EnjuParser_T78 | arg1Of | line,a |
EnjuParser_R79 | EnjuParser_T83 | EnjuParser_T79 | arg1Of | line,HL-1 |
EnjuParser_R80 | EnjuParser_T83 | EnjuParser_T80 | arg1Of | line,mouse |
EnjuParser_R81 | EnjuParser_T83 | EnjuParser_T81 | arg1Of | line,cardiomyocyte |
EnjuParser_R82 | EnjuParser_T83 | EnjuParser_T82 | arg1Of | line,cell |
EnjuParser_R83 | EnjuParser_T72 | EnjuParser_T84 | arg1Of | used,under |
EnjuParser_R84 | EnjuParser_T85 | EnjuParser_T84 | arg2Of | exposure,under |
EnjuParser_R85 | EnjuParser_T85 | EnjuParser_T86 | arg1Of | exposure,to |
EnjuParser_R86 | EnjuParser_T88 | EnjuParser_T86 | arg2Of | peroxide,to |
EnjuParser_R87 | EnjuParser_T88 | EnjuParser_T87 | arg1Of | peroxide,hydrogen |
EnjuParser_R88 | EnjuParser_T72 | EnjuParser_T89 | arg1Of | used,"," |
EnjuParser_R89 | EnjuParser_T71 | EnjuParser_T90 | arg1Of | we,finding |
EnjuParser_R90 | EnjuParser_T93 | EnjuParser_T90 | arg2Of | peptides,finding |
EnjuParser_R91 | EnjuParser_T72 | EnjuParser_T90 | modOf | used,finding |
EnjuParser_R92 | EnjuParser_T93 | EnjuParser_T91 | arg1Of | peptides,1763 |
EnjuParser_R93 | EnjuParser_T93 | EnjuParser_T92 | arg2Of | peptides,glutathionylated |
EnjuParser_R94 | EnjuParser_T93 | EnjuParser_T94 | arg1Of | peptides,with |
EnjuParser_R95 | EnjuParser_T98 | EnjuParser_T94 | arg2Of | sites,with |
EnjuParser_R96 | EnjuParser_T98 | EnjuParser_T95 | arg1Of | sites,specific |
EnjuParser_R97 | EnjuParser_T98 | EnjuParser_T96 | arg1Of | sites,Cys |
EnjuParser_R98 | EnjuParser_T98 | EnjuParser_T97 | arg1Of | sites,modification |
EnjuParser_R99 | EnjuParser_T98 | EnjuParser_T99 | arg1Of | sites,"," |
EnjuParser_R100 | EnjuParser_T98 | EnjuParser_T100 | arg1Of | sites,which |
EnjuParser_R101 | EnjuParser_T98 | EnjuParser_T101 | arg1Of | sites,include |
EnjuParser_R102 | EnjuParser_T104 | EnjuParser_T101 | arg2Of | proteins,include |
EnjuParser_R103 | EnjuParser_T104 | EnjuParser_T102 | arg1Of | proteins,many |
EnjuParser_R104 | EnjuParser_T104 | EnjuParser_T103 | arg1Of | proteins,muscle-specific |
EnjuParser_R105 | EnjuParser_T108 | EnjuParser_T105 | arg1Of | analyses,Bioinformatic |
EnjuParser_R106 | EnjuParser_T105 | EnjuParser_T106 | arg1Of | Bioinformatic,and |
EnjuParser_R107 | EnjuParser_T107 | EnjuParser_T106 | arg2Of | cluster,and |
EnjuParser_R108 | EnjuParser_T108 | EnjuParser_T107 | arg1Of | analyses,cluster |
EnjuParser_R109 | EnjuParser_T108 | EnjuParser_T109 | arg1Of | analyses,found |
EnjuParser_R110 | EnjuParser_T112 | EnjuParser_T109 | arg2Of | proteins,found |
EnjuParser_R111 | EnjuParser_T112 | EnjuParser_T110 | arg1Of | proteins,125 |
EnjuParser_R112 | EnjuParser_T112 | EnjuParser_T111 | arg2Of | proteins,glutathionylated |
EnjuParser_R113 | EnjuParser_T112 | EnjuParser_T113 | arg1Of | proteins,"," |
EnjuParser_R114 | EnjuParser_T116 | EnjuParser_T114 | arg1Of | or,whose |
EnjuParser_R115 | EnjuParser_T112 | EnjuParser_T114 | arg2Of | proteins,whose |
EnjuParser_R116 | EnjuParser_T115 | EnjuParser_T116 | arg1Of | mutations,or |
EnjuParser_R117 | EnjuParser_T117 | EnjuParser_T116 | arg2Of | dysfunctions,or |
EnjuParser_R118 | EnjuParser_T116 | EnjuParser_T118 | arg1Of | or,are |
EnjuParser_R119 | EnjuParser_T119 | EnjuParser_T118 | arg2Of | associated,are |
EnjuParser_R120 | EnjuParser_T116 | EnjuParser_T119 | arg2Of | or,associated |
EnjuParser_R121 | EnjuParser_T119 | EnjuParser_T120 | arg1Of | associated,with |
EnjuParser_R122 | EnjuParser_T121 | EnjuParser_T120 | arg2Of | cardiomyopathy,with |
EnjuParser_R123 | EnjuParser_T112 | EnjuParser_T122 | arg1Of | proteins,"," |
EnjuParser_R124 | EnjuParser_T123 | EnjuParser_T124 | arg1Of | many,of |
EnjuParser_R125 | EnjuParser_T112 | EnjuParser_T124 | arg2Of | proteins,of |
EnjuParser_R126 | EnjuParser_T112 | EnjuParser_T125 | arg1Of | proteins,which |
EnjuParser_R127 | EnjuParser_T123 | EnjuParser_T126 | arg1Of | many,include |
EnjuParser_R128 | EnjuParser_T135 | EnjuParser_T126 | arg2Of | and,include |
EnjuParser_R129 | EnjuParser_T131 | EnjuParser_T127 | arg1Of | proteins,sarcomeric |
EnjuParser_R130 | EnjuParser_T131 | EnjuParser_T128 | arg1Of | proteins,structural |
EnjuParser_R131 | EnjuParser_T128 | EnjuParser_T129 | arg1Of | structural,and |
EnjuParser_R132 | EnjuParser_T130 | EnjuParser_T129 | arg2Of | contractile,and |
EnjuParser_R133 | EnjuParser_T131 | EnjuParser_T130 | arg1Of | proteins,contractile |
EnjuParser_R134 | EnjuParser_T131 | EnjuParser_T132 | arg1Of | proteins,"," |
EnjuParser_R135 | EnjuParser_T133 | EnjuParser_T132 | arg2Of | chaperone,"," |
EnjuParser_R136 | EnjuParser_T135 | EnjuParser_T134 | arg1Of | and,"," |
EnjuParser_R137 | EnjuParser_T132 | EnjuParser_T135 | arg1Of | ",",and |
EnjuParser_R138 | EnjuParser_T140 | EnjuParser_T135 | arg2Of | proteins,and |
EnjuParser_R139 | EnjuParser_T140 | EnjuParser_T136 | arg1Of | proteins,other |
EnjuParser_R140 | EnjuParser_T140 | EnjuParser_T137 | arg1Of | proteins,signaling |
EnjuParser_R141 | EnjuParser_T137 | EnjuParser_T138 | arg1Of | signaling,or |
EnjuParser_R142 | EnjuParser_T139 | EnjuParser_T138 | arg2Of | regulatory,or |
EnjuParser_R143 | EnjuParser_T140 | EnjuParser_T139 | arg1Of | proteins,regulatory |
EnjuParser_R144 | EnjuParser_T143 | EnjuParser_T142 | arg1Of | provide,further |
EnjuParser_R145 | EnjuParser_T141 | EnjuParser_T143 | arg1Of | We,provide |
EnjuParser_R146 | EnjuParser_T145 | EnjuParser_T143 | arg2Of | implication,provide |
EnjuParser_R147 | EnjuParser_T145 | EnjuParser_T144 | arg1Of | implication,functional |
EnjuParser_R148 | EnjuParser_T145 | EnjuParser_T146 | arg1Of | implication,of |
EnjuParser_R149 | EnjuParser_T147 | EnjuParser_T146 | arg2Of | glutathionylation,of |
EnjuParser_R150 | EnjuParser_T143 | EnjuParser_T148 | arg1Of | provide,for |
EnjuParser_R151 | EnjuParser_T151 | EnjuParser_T148 | arg2Of | proteins,for |
EnjuParser_R152 | EnjuParser_T151 | EnjuParser_T149 | arg1Of | proteins,several |
EnjuParser_R153 | EnjuParser_T151 | EnjuParser_T150 | arg2Of | proteins,identified |
EnjuParser_R154 | EnjuParser_T151 | EnjuParser_T152 | arg1Of | proteins,"," |
EnjuParser_R155 | EnjuParser_T151 | EnjuParser_T153 | arg1Of | proteins,including |
EnjuParser_R156 | EnjuParser_T161 | EnjuParser_T153 | arg2Of | and,including |
EnjuParser_R157 | EnjuParser_T154 | EnjuParser_T155 | arg1Of | CSRP3/MLP,and |
EnjuParser_R158 | EnjuParser_T156 | EnjuParser_T155 | arg2Of | complex,and |
EnjuParser_R159 | EnjuParser_T156 | EnjuParser_T157 | arg1Of | complex,I |
EnjuParser_R160 | EnjuParser_T155 | EnjuParser_T158 | arg1Of | and,"," |
EnjuParser_R161 | EnjuParser_T159 | EnjuParser_T158 | arg2Of | II,"," |
EnjuParser_R162 | EnjuParser_T161 | EnjuParser_T160 | arg1Of | and,"," |
EnjuParser_R163 | EnjuParser_T158 | EnjuParser_T161 | arg1Of | ",",and |
EnjuParser_R164 | EnjuParser_T162 | EnjuParser_T161 | arg2Of | III,and |
EnjuParser_R165 | EnjuParser_T143 | EnjuParser_T163 | arg1Of | provide,"," |
EnjuParser_R166 | EnjuParser_T143 | EnjuParser_T164 | arg1Of | provide,by |
EnjuParser_R167 | EnjuParser_T165 | EnjuParser_T164 | arg2Of | analyzing,by |
EnjuParser_R168 | EnjuParser_T141 | EnjuParser_T165 | arg1Of | We,analyzing |
EnjuParser_R169 | EnjuParser_T167 | EnjuParser_T165 | arg2Of | sites,analyzing |
EnjuParser_R170 | EnjuParser_T167 | EnjuParser_T166 | arg2Of | sites,glutathionylated |
EnjuParser_R171 | EnjuParser_T165 | EnjuParser_T168 | arg1Of | analyzing,in |
EnjuParser_R172 | EnjuParser_T170 | EnjuParser_T168 | arg2Of | structures,in |
EnjuParser_R173 | EnjuParser_T170 | EnjuParser_T169 | arg1Of | structures,their |
EnjuParser_R174 | EnjuParser_T172 | EnjuParser_T171 | arg1Of | report,Our |
EnjuParser_R175 | EnjuParser_T172 | EnjuParser_T173 | arg1Of | report,establishes |
EnjuParser_R176 | EnjuParser_T176 | EnjuParser_T173 | arg2Of | method,establishes |
EnjuParser_R177 | EnjuParser_T176 | EnjuParser_T174 | arg1Of | method,a |
EnjuParser_R178 | EnjuParser_T176 | EnjuParser_T175 | arg1Of | method,chemoselective |
EnjuParser_R179 | EnjuParser_T176 | EnjuParser_T177 | arg1Of | method,for |
EnjuParser_R180 | EnjuParser_T179 | EnjuParser_T177 | arg2Of | identification,for |
EnjuParser_R181 | EnjuParser_T179 | EnjuParser_T178 | arg1Of | identification,direct |
EnjuParser_R182 | EnjuParser_T179 | EnjuParser_T180 | arg1Of | identification,of |
EnjuParser_R183 | EnjuParser_T182 | EnjuParser_T180 | arg2Of | proteins,of |
EnjuParser_R184 | EnjuParser_T182 | EnjuParser_T181 | arg2Of | proteins,glutathionylated |
EnjuParser_R185 | EnjuParser_T173 | EnjuParser_T183 | arg1Of | establishes,and |
EnjuParser_R186 | EnjuParser_T184 | EnjuParser_T183 | arg2Of | provides,and |
EnjuParser_R187 | EnjuParser_T172 | EnjuParser_T184 | arg1Of | report,provides |
EnjuParser_R188 | EnjuParser_T187 | EnjuParser_T184 | arg2Of | proteins,provides |
EnjuParser_R189 | EnjuParser_T187 | EnjuParser_T185 | arg1Of | proteins,potential |
EnjuParser_R190 | EnjuParser_T187 | EnjuParser_T186 | arg1Of | proteins,target |
EnjuParser_R191 | EnjuParser_T189 | EnjuParser_T188 | arg1Of | glutathionylation,whose |
EnjuParser_R192 | EnjuParser_T187 | EnjuParser_T188 | arg2Of | proteins,whose |
EnjuParser_R193 | EnjuParser_T189 | EnjuParser_T190 | arg1Of | glutathionylation,may |
EnjuParser_R194 | EnjuParser_T191 | EnjuParser_T190 | arg2Of | contribute,may |
EnjuParser_R195 | EnjuParser_T189 | EnjuParser_T191 | arg1Of | glutathionylation,contribute |
EnjuParser_R196 | EnjuParser_T191 | EnjuParser_T192 | arg1Of | contribute,to |
EnjuParser_R197 | EnjuParser_T194 | EnjuParser_T192 | arg2Of | diseases,to |
EnjuParser_R198 | EnjuParser_T194 | EnjuParser_T193 | arg1Of | diseases,muscle |
Anatomy-MAT
Id | Subject | Object | Predicate | Lexical cue | mat_id |
---|---|---|---|---|---|
T1 | 753-759 | Body_part | denotes | muscle | http://purl.obolibrary.org/obo/MAT_0000025 |
T2 | 1428-1434 | Body_part | denotes | muscle | http://purl.obolibrary.org/obo/MAT_0000025 |
GlyCosmos15-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T1 | 187-210 | Phenotype | denotes | cardiovascular diseases | HP:0001626 |
T2 | 222-236 | Phenotype | denotes | cardiomyopathy | HP:0001638 |
T3 | 374-390 | Phenotype | denotes | oxidative stress | HP:0025464 |
T4 | 903-917 | Phenotype | denotes | cardiomyopathy | HP:0001638 |
mondo_disease
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T1 | 187-210 | Disease | denotes | cardiovascular diseases | http://purl.obolibrary.org/obo/MONDO_0004995 |
T2 | 222-236 | Disease | denotes | cardiomyopathy | http://purl.obolibrary.org/obo/MONDO_0004994 |
T3 | 903-917 | Disease | denotes | cardiomyopathy | http://purl.obolibrary.org/obo/MONDO_0004994 |
NCBITAXON
Id | Subject | Object | Predicate | Lexical cue | db_id |
---|---|---|---|---|---|
T1 | 590-595 | OrganismTaxon | denotes | mouse | 10088|10090 |
Anatomy-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T1 | 57-71 | Body_part | denotes | Cardiomyocytes | http://purl.obolibrary.org/obo/CL_0000746 |
T2 | 490-504 | Body_part | denotes | cardiomyocytes | http://purl.obolibrary.org/obo/CL_0000746 |
T3 | 596-609 | Body_part | denotes | cardiomyocyte | http://purl.obolibrary.org/obo/CL_0000746 |
T4 | 753-759 | Body_part | denotes | muscle | http://purl.obolibrary.org/obo/UBERON_0001630|http://purl.obolibrary.org/obo/UBERON_0005090 |
T6 | 1428-1434 | Body_part | denotes | muscle | http://purl.obolibrary.org/obo/UBERON_0001630|http://purl.obolibrary.org/obo/UBERON_0005090 |
Glycosmos15-CL
Id | Subject | Object | Predicate | Lexical cue | cl_id |
---|---|---|---|---|---|
T1 | 57-71 | Cell | denotes | Cardiomyocytes | http://purl.obolibrary.org/obo/CL:0000746 |
T2 | 490-504 | Cell | denotes | cardiomyocytes | http://purl.obolibrary.org/obo/CL:0000746 |
T3 | 596-609 | Cell | denotes | cardiomyocyte | http://purl.obolibrary.org/obo/CL:0000746 |