> top > docs > PubMed:30669833 > annotations

PubMed:30669833 JSONTXT

Annnotations TAB JSON ListView MergeView

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 64-79 Disease denotes Prostate Cancer http://purl.obolibrary.org/obo/MONDO_0008315
T2 218-233 Disease denotes prostate cancer http://purl.obolibrary.org/obo/MONDO_0008315
T3 235-238 Disease denotes PCa http://purl.obolibrary.org/obo/MONDO_0008315
T4 388-391 Disease denotes PCa http://purl.obolibrary.org/obo/MONDO_0008315
T5 607-610 Disease denotes PCa http://purl.obolibrary.org/obo/MONDO_0008315
T6 617-644 Disease denotes benign prostate hyperplasia http://purl.obolibrary.org/obo/MONDO_0010811
T7 646-649 Disease denotes BPH http://purl.obolibrary.org/obo/MONDO_0010811
T8 897-900 Disease denotes PCa http://purl.obolibrary.org/obo/MONDO_0008315
T9 923-926 Disease denotes BPH http://purl.obolibrary.org/obo/MONDO_0010811
T10 1018-1021 Disease denotes PCa http://purl.obolibrary.org/obo/MONDO_0008315
T11 1148-1151 Disease denotes PCa http://purl.obolibrary.org/obo/MONDO_0008315
T12 1159-1162 Disease denotes BPH http://purl.obolibrary.org/obo/MONDO_0010811
T13 1438-1441 Disease denotes PCa http://purl.obolibrary.org/obo/MONDO_0008315
T14 1702-1705 Disease denotes PCa http://purl.obolibrary.org/obo/MONDO_0008315

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 830-836 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL

GlyCosmos15-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 64-72 Body_part denotes Prostate http://purl.obolibrary.org/obo/UBERON_0002367
T2 115-120 Body_part denotes Serum http://purl.obolibrary.org/obo/UBERON_0001977
T3 121-129 Body_part denotes prostate http://purl.obolibrary.org/obo/UBERON_0002367
T4 218-226 Body_part denotes prostate http://purl.obolibrary.org/obo/UBERON_0002367
T5 624-632 Body_part denotes prostate http://purl.obolibrary.org/obo/UBERON_0002367

GlyCosmos15-HP

Id Subject Object Predicate Lexical cue hp_id
T1 64-79 Phenotype denotes Prostate Cancer HP:0012125
T2 218-233 Phenotype denotes prostate cancer HP:0012125
T3 235-238 Phenotype denotes PCa HP:0012125
T4 388-391 Phenotype denotes PCa HP:0012125
T5 607-610 Phenotype denotes PCa HP:0012125
T6 617-644 Phenotype denotes benign prostate hyperplasia HP:0008711
T7 646-649 Phenotype denotes BPH HP:0008711
T8 897-900 Phenotype denotes PCa HP:0012125
T9 923-926 Phenotype denotes BPH HP:0008711
T10 1018-1021 Phenotype denotes PCa HP:0012125
T11 1148-1151 Phenotype denotes PCa HP:0012125
T12 1159-1162 Phenotype denotes BPH HP:0008711
T13 1438-1441 Phenotype denotes PCa HP:0012125
T14 1702-1705 Phenotype denotes PCa HP:0012125

GlyCosmos15-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 64-79 Disease denotes Prostate Cancer http://purl.obolibrary.org/obo/MONDO_0008315
T2 218-233 Disease denotes prostate cancer http://purl.obolibrary.org/obo/MONDO_0008315
T3 235-238 Disease denotes PCa http://purl.obolibrary.org/obo/MONDO_0008315
T4 388-391 Disease denotes PCa http://purl.obolibrary.org/obo/MONDO_0008315
T5 607-610 Disease denotes PCa http://purl.obolibrary.org/obo/MONDO_0008315
T6 617-644 Disease denotes benign prostate hyperplasia http://purl.obolibrary.org/obo/MONDO_0010811
T7 646-649 Disease denotes BPH http://purl.obolibrary.org/obo/MONDO_0010811
T8 897-900 Disease denotes PCa http://purl.obolibrary.org/obo/MONDO_0008315
T9 923-926 Disease denotes BPH http://purl.obolibrary.org/obo/MONDO_0010811
T10 1018-1021 Disease denotes PCa http://purl.obolibrary.org/obo/MONDO_0008315
T11 1148-1151 Disease denotes PCa http://purl.obolibrary.org/obo/MONDO_0008315
T12 1159-1162 Disease denotes BPH http://purl.obolibrary.org/obo/MONDO_0010811
T13 1438-1441 Disease denotes PCa http://purl.obolibrary.org/obo/MONDO_0008315
T14 1702-1705 Disease denotes PCa http://purl.obolibrary.org/obo/MONDO_0008315

GlyCosmos15-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 64-72 Body_part denotes Prostate http://purl.obolibrary.org/obo/MAT_0000078
T2 121-129 Body_part denotes prostate http://purl.obolibrary.org/obo/MAT_0000078
T3 218-226 Body_part denotes prostate http://purl.obolibrary.org/obo/MAT_0000078
T4 624-632 Body_part denotes prostate http://purl.obolibrary.org/obo/MAT_0000078

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-114 Sentence denotes Identification of Multisialylated LacdiNAc Structures as Highly Prostate Cancer Specific Glycan Signatures on PSA.
T2 115-299 Sentence denotes Serum prostate-specific antigen (PSA) test is the current gold standard for screening and diagnosis of prostate cancer (PCa), while overdiagnosis and overtreatment are social problems.
T3 300-563 Sentence denotes In order to improve the specificity and exclude a false positive diagnosis in PSA test, PCa-specific glycosylation subtypes of PSA were explored using in-depth quantitative profiling of PSA glycoforms based on mass spectrometric oxonium ion monitoring technology.
T4 564-776 Sentence denotes As a result of analysis using sera from 15 PCa or 15 benign prostate hyperplasia (BPH) patients whose PSA levels were in the "gray zone" (4.0-10.0 ng/mL), 52 glycan structures on PSA were quantitatively observed.
T5 777-933 Sentence denotes We found that abundance of multisialylated LacdiNAc (GalNAcβ1-4GlcNAc) structures were significantly upregulated in the PCa group compared to the BPH group.
T6 934-1061 Sentence denotes A couple of those glycoforms were then extracted and subjected to establish a novel PCa-specific diagnosis model (PSA G-index).
T7 1062-1299 Sentence denotes When the diagnostic power was assessed using an independent validation sample set (15 PCa and 15 BPH patients in the PSA gray zone), an AUC of PSA G-index was 1.00, while that of total PSA or PSA f/T ratio was 0.50 or 0.60, respectively.
T8 1300-1381 Sentence denotes Moreover, both PSA glycoforms showed significant correlation with Gleason scores.
T9 1382-1522 Sentence denotes Lectin histochemical staining analysis also showed that PCa cells overexpressed glycoproteins containing LacdiNAc and sialic acids moieties.
T10 1523-1706 Sentence denotes Thus, PSA G-index could serve as not only an effective secondary screening method to exclude false positive diagnosis in PSA screening, but also a potential grading biomarker for PCa.

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 830-836 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL

GlyCosmos15-Lectin-Jamboree

Id Subject Object Predicate Lexical cue glycosmos_id
T1 110-113 Lectin denotes PSA GL_000021
T2 148-151 Lectin denotes PSA GL_000021
T3 378-381 Lectin denotes PSA GL_000021
T4 427-430 Lectin denotes PSA GL_000021
T5 486-489 Lectin denotes PSA GL_000021
T6 666-669 Lectin denotes PSA GL_000021
T7 743-746 Lectin denotes PSA GL_000021
T8 1048-1051 Lectin denotes PSA GL_000021
T9 1179-1182 Lectin denotes PSA GL_000021
T10 1205-1208 Lectin denotes PSA GL_000021
T11 1247-1250 Lectin denotes PSA GL_000021
T12 1254-1257 Lectin denotes PSA GL_000021
T13 1315-1318 Lectin denotes PSA GL_000021
T14 1529-1532 Lectin denotes PSA GL_000021
T15 1644-1647 Lectin denotes PSA GL_000021

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 64-72 Body_part denotes Prostate http://purl.obolibrary.org/obo/UBERON_0002367
T2 115-120 Body_part denotes Serum http://purl.obolibrary.org/obo/UBERON_0001977
T3 121-129 Body_part denotes prostate http://purl.obolibrary.org/obo/UBERON_0002367
T4 218-226 Body_part denotes prostate http://purl.obolibrary.org/obo/UBERON_0002367
T5 624-632 Body_part denotes prostate http://purl.obolibrary.org/obo/UBERON_0002367

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 64-72 Body_part denotes Prostate http://purl.obolibrary.org/obo/MAT_0000078
T2 121-129 Body_part denotes prostate http://purl.obolibrary.org/obo/MAT_0000078
T3 218-226 Body_part denotes prostate http://purl.obolibrary.org/obo/MAT_0000078
T4 624-632 Body_part denotes prostate http://purl.obolibrary.org/obo/MAT_0000078

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 64-79 Phenotype denotes Prostate Cancer HP:0012125
T2 218-233 Phenotype denotes prostate cancer HP:0012125
T3 235-238 Phenotype denotes PCa HP:0012125
T4 388-391 Phenotype denotes PCa HP:0012125
T5 607-610 Phenotype denotes PCa HP:0012125
T6 617-644 Phenotype denotes benign prostate hyperplasia HP:0008711
T7 646-649 Phenotype denotes BPH HP:0008711
T8 897-900 Phenotype denotes PCa HP:0012125
T9 923-926 Phenotype denotes BPH HP:0008711
T10 1018-1021 Phenotype denotes PCa HP:0012125
T11 1148-1151 Phenotype denotes PCa HP:0012125
T12 1159-1162 Phenotype denotes BPH HP:0008711
T13 1438-1441 Phenotype denotes PCa HP:0012125
T14 1702-1705 Phenotype denotes PCa HP:0012125