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sentences

Id	Subject	Object	Predicate	Lexical cue
T1	0-128	Sentence	denotes	Serum responsive proteome reveals correlation between oxidative phosphorylation and morphogenesis in Candida albicans ATCC10231.
T2	129-315	Sentence	denotes	To understand the impact of fetal bovine serum (FBS) on metabolism and cellular architecture in addition to morphogenesis, we have identified FBS responsive proteome of Candida albicans.
T3	316-410	Sentence	denotes	FBS induced 34% hyphae and 60% pseudohyphae in C. albicans at 30 °C while 98% hyphae at 37 °C.
T4	411-518	Sentence	denotes	LC-MS/MS analysis revealed that 285 proteins modulated significantly in response to FBS at 30 °C and 37 °C.
T5	519-640	Sentence	denotes	Out of which 152 were upregulated and 62 were downregulated at 30 °C while 18 were up and 53 were downregulated at 37 °C.
T6	641-886	Sentence	denotes	Functional annotation suggests that FBS may inhibit glycolysis and fermentative pathway and enhance oxidative phosphorylation (OxPhos), TCA cycle, amino acid and fatty acid metabolism indicating a use of alternative energy source by C. albicans.
T7	887-1040	Sentence	denotes	OxPhos inhibition assay using sodium azide corroborated the correlation between inhibition of glycolysis and enhanced OxPhos with pseudohyphae formation.
T8	1041-1214	Sentence	denotes	C. albicans induced hyphae in response to FBS irrespective of down regulation of Ras1,Asr1/Asr2, indicates the possible involvement of MAPK and cAMP-PKA independent pathway.
T9	1215-1392	Sentence	denotes	The Cell wall of cells grown in presence of FBS at 30 °C was rich in mannan, Beta 1,3-glucan and chitin while membranes were rich in ergosterol compared to those grown at 37 °C.
T10	1393-1419	Sentence	denotes	SIGNIFICANCE OF THE STUDY:
T11	1420-1551	Sentence	denotes	This is the first study suggesting a correlation between OxPhos and morphogenesis especially pseudohyphae formation in C. albicans.
T12	1552-1699	Sentence	denotes	Our data also indicate that fetal bovine serum (FBS) induced morphogenesis is multifactorial and may involve MAPK and cAMP-PKA independent pathway.
T13	1700-1855	Sentence	denotes	In addition to morphogenesis, our study provides an insight in to the modulation of metabolism and cellular architecture of C. albicans in response to FBS.

Glycosmos6-MAT

Id	Subject	Object	Predicate	Lexical cue
T1	332-338	http://purl.obolibrary.org/obo/MAT_0000010	denotes	hyphae
T2	394-400	http://purl.obolibrary.org/obo/MAT_0000010	denotes	hyphae
T3	1061-1067	http://purl.obolibrary.org/obo/MAT_0000010	denotes	hyphae

mondo_disease

Id	Subject	Object	Predicate	Lexical cue	mondo_id
T1	408-413	Disease	denotes	C. LC	http://purl.obolibrary.org/obo/MONDO_0004315

Glycan-GlyCosmos

Id	Subject	Object	Predicate	Lexical cue	image
T1	1312-1318	Glycan	denotes	chitin	https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY

GlyCosmos15-MONDO

Id	Subject	Object	Predicate	Lexical cue	mondo_id
T1	408-413	Disease	denotes	C. LC	http://purl.obolibrary.org/obo/MONDO_0004315

GlyCosmos15-NCBITAXON

Id	Subject	Object	Predicate	Lexical cue	db_id
T1	101-117	OrganismTaxon	denotes	Candida albicans	5476
T2	163-169	OrganismTaxon	denotes	bovine	9913
T3	298-314	OrganismTaxon	denotes	Candida albicans	5476
T4	1586-1592	OrganismTaxon	denotes	bovine	9913

GlyCosmos15-UBERON

Id	Subject	Object	Predicate	Lexical cue	uberon_id
T1	1224-1228	Body_part	denotes	wall	http://purl.obolibrary.org/obo/UBERON_0000060
T2	1325-1334	Body_part	denotes	membranes	http://purl.obolibrary.org/obo/GO_0016020\|http://purl.obolibrary.org/obo/UBERON_0000094\|http://purl.obolibrary.org/obo/UBERON_0000158

GlyCosmos15-MAT

Id	Subject	Object	Predicate	Lexical cue	mat_id
T1	332-338	Body_part	denotes	hyphae	http://purl.obolibrary.org/obo/MAT_0000010
T2	394-400	Body_part	denotes	hyphae	http://purl.obolibrary.org/obo/MAT_0000010
T3	1061-1067	Body_part	denotes	hyphae	http://purl.obolibrary.org/obo/MAT_0000010

sentences

Id	Subject	Object	Predicate	Lexical cue
T1	0-128	Sentence	denotes	Serum responsive proteome reveals correlation between oxidative phosphorylation and morphogenesis in Candida albicans ATCC10231.
T2	129-315	Sentence	denotes	To understand the impact of fetal bovine serum (FBS) on metabolism and cellular architecture in addition to morphogenesis, we have identified FBS responsive proteome of Candida albicans.
T3	316-410	Sentence	denotes	FBS induced 34% hyphae and 60% pseudohyphae in C. albicans at 30 °C while 98% hyphae at 37 °C.
T4	411-518	Sentence	denotes	LC-MS/MS analysis revealed that 285 proteins modulated significantly in response to FBS at 30 °C and 37 °C.
T5	519-640	Sentence	denotes	Out of which 152 were upregulated and 62 were downregulated at 30 °C while 18 were up and 53 were downregulated at 37 °C.
T6	641-886	Sentence	denotes	Functional annotation suggests that FBS may inhibit glycolysis and fermentative pathway and enhance oxidative phosphorylation (OxPhos), TCA cycle, amino acid and fatty acid metabolism indicating a use of alternative energy source by C. albicans.
T7	887-1040	Sentence	denotes	OxPhos inhibition assay using sodium azide corroborated the correlation between inhibition of glycolysis and enhanced OxPhos with pseudohyphae formation.
T8	1041-1214	Sentence	denotes	C. albicans induced hyphae in response to FBS irrespective of down regulation of Ras1,Asr1/Asr2, indicates the possible involvement of MAPK and cAMP-PKA independent pathway.
T9	1215-1392	Sentence	denotes	The Cell wall of cells grown in presence of FBS at 30 °C was rich in mannan, Beta 1,3-glucan and chitin while membranes were rich in ergosterol compared to those grown at 37 °C.
T10	1393-1419	Sentence	denotes	SIGNIFICANCE OF THE STUDY:
T11	1420-1551	Sentence	denotes	This is the first study suggesting a correlation between OxPhos and morphogenesis especially pseudohyphae formation in C. albicans.
T12	1552-1699	Sentence	denotes	Our data also indicate that fetal bovine serum (FBS) induced morphogenesis is multifactorial and may involve MAPK and cAMP-PKA independent pathway.
T13	1700-1855	Sentence	denotes	In addition to morphogenesis, our study provides an insight in to the modulation of metabolism and cellular architecture of C. albicans in response to FBS.

GlyCosmos15-Sentences

Id	Subject	Object	Predicate	Lexical cue
T1	0-128	Sentence	denotes	Serum responsive proteome reveals correlation between oxidative phosphorylation and morphogenesis in Candida albicans ATCC10231.
T2	129-315	Sentence	denotes	To understand the impact of fetal bovine serum (FBS) on metabolism and cellular architecture in addition to morphogenesis, we have identified FBS responsive proteome of Candida albicans.
T3	316-886	Sentence	denotes	FBS induced 34% hyphae and 60% pseudohyphae in C. albicans at 30 °C while 98% hyphae at 37 °C. LC-MS/MS analysis revealed that 285 proteins modulated significantly in response to FBS at 30 °C and 37 °C. Out of which 152 were upregulated and 62 were downregulated at 30 °C while 18 were up and 53 were downregulated at 37 °C. Functional annotation suggests that FBS may inhibit glycolysis and fermentative pathway and enhance oxidative phosphorylation (OxPhos), TCA cycle, amino acid and fatty acid metabolism indicating a use of alternative energy source by C. albicans.
T4	887-1040	Sentence	denotes	OxPhos inhibition assay using sodium azide corroborated the correlation between inhibition of glycolysis and enhanced OxPhos with pseudohyphae formation.
T5	1041-1214	Sentence	denotes	C. albicans induced hyphae in response to FBS irrespective of down regulation of Ras1,Asr1/Asr2, indicates the possible involvement of MAPK and cAMP-PKA independent pathway.
T6	1215-1392	Sentence	denotes	The Cell wall of cells grown in presence of FBS at 30 °C was rich in mannan, Beta 1,3-glucan and chitin while membranes were rich in ergosterol compared to those grown at 37 °C.
T7	1393-1419	Sentence	denotes	SIGNIFICANCE OF THE STUDY:
T8	1420-1551	Sentence	denotes	This is the first study suggesting a correlation between OxPhos and morphogenesis especially pseudohyphae formation in C. albicans.
T9	1552-1699	Sentence	denotes	Our data also indicate that fetal bovine serum (FBS) induced morphogenesis is multifactorial and may involve MAPK and cAMP-PKA independent pathway.
T10	1700-1855	Sentence	denotes	In addition to morphogenesis, our study provides an insight in to the modulation of metabolism and cellular architecture of C. albicans in response to FBS.

GlyCosmos15-Glycan

Id	Subject	Object	Predicate	Lexical cue	image
T1	1312-1318	Glycan	denotes	chitin	https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY

NCBITAXON

Id	Subject	Object	Predicate	Lexical cue	db_id
T1	101-117	OrganismTaxon	denotes	Candida albicans	5476
T2	163-169	OrganismTaxon	denotes	bovine	9913
T3	298-314	OrganismTaxon	denotes	Candida albicans	5476
T4	1586-1592	OrganismTaxon	denotes	bovine	9913

Anatomy-UBERON

Id	Subject	Object	Predicate	Lexical cue	uberon_id
T1	1224-1228	Body_part	denotes	wall	http://purl.obolibrary.org/obo/UBERON_0000060
T2	1325-1334	Body_part	denotes	membranes	http://purl.obolibrary.org/obo/GO_0016020\|http://purl.obolibrary.org/obo/UBERON_0000094\|http://purl.obolibrary.org/obo/UBERON_0000158

Anatomy-MAT

Id	Subject	Object	Predicate	Lexical cue	mat_id
T1	332-338	Body_part	denotes	hyphae	http://purl.obolibrary.org/obo/MAT_0000010
T2	394-400	Body_part	denotes	hyphae	http://purl.obolibrary.org/obo/MAT_0000010
T3	1061-1067	Body_part	denotes	hyphae	http://purl.obolibrary.org/obo/MAT_0000010