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Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-130 Sentence denotes Arginase 1 deletion in myeloid cells affects the inflammatory response in allergic asthma, but not lung mechanics, in female mice.
T2 131-241 Sentence denotes BACKGROUND: (Over-)expression of arginase may limit local availability of arginine for nitric oxide synthesis.
T3 242-433 Sentence denotes We investigated the significance of arginase1 (ARG1) for the development of airway hyperresponsiveness (AHR) and lung inflammation in female mice with ovalbumin (OVA)-induced allergic asthma.
T4 434-442 Sentence denotes METHODS:
T5 443-517 Sentence denotes Arg1 was ablated in the lung by crossing Arg1 fl/fl and Tie2Cre tg/- mice.
T6 518-632 Sentence denotes OVA sensitization and challenge were conducted, and AHR to methacholine was determined using the Flexivent system.
T7 633-803 Sentence denotes Changes in gene expression, chemokine and cytokine secretion, plasma IgE, and lung histology were quantified using RT-qPCR, ELISA, and immunohistochemistry, respectively.
T8 804-812 Sentence denotes RESULTS:
T9 813-1160 Sentence denotes Arg1 ablation had no influence on the development of OVA-induced AHR, but attenuated OVA-induced increases in expression of Arg2 and Nos2, Slc7a1, Slc7a2, and Slc7a7 (arginine transporters), Il4, Il5 and Il13 (TH2-type cytokines), Ccl2 and Ccl11 (chemokines), Ifng (TH1-type cytokine), Clca3 and Muc5ac (goblet cell markers), and OVA-specific IgE.
T10 1161-1293 Sentence denotes Pulmonary IL-10 protein content increased, but IL-4, IL-5, IL-13, TNFα and IFNγ content, and lung histopathology, were not affected.
T11 1294-1464 Sentence denotes Arg1 elimination also decreased number and tightness of correlations between adaptive changes in lung function and inflammatory parameters in OVA/OVA-treated female mice.
T12 1465-1608 Sentence denotes OVA/OVA-treated female mice mounted a higher OVA-IgE response than males, but the correlation between lung function and inflammation was lower.
T13 1609-1862 Sentence denotes Arg1-deficient OVA/OVA-treated females differed from males in a more pronounced decline of arginine-metabolizing and -transporting genes, higher plasma arginine levels, a smaller OVA-specific IgE response, and no improvement of peripheral lung function.
T14 1863-1874 Sentence denotes CONCLUSION:
T15 1875-2088 Sentence denotes Complete ablation of Arg1 in the lung affects mRNA abundance of arginine-transporting and -metabolizing genes, and pro-inflammatory genes, but not methacholine responsiveness or accumulation of inflammatory cells.
T1 0-130 Sentence denotes Arginase 1 deletion in myeloid cells affects the inflammatory response in allergic asthma, but not lung mechanics, in female mice.
T2 131-241 Sentence denotes BACKGROUND: (Over-)expression of arginase may limit local availability of arginine for nitric oxide synthesis.
T3 242-433 Sentence denotes We investigated the significance of arginase1 (ARG1) for the development of airway hyperresponsiveness (AHR) and lung inflammation in female mice with ovalbumin (OVA)-induced allergic asthma.
T4 434-442 Sentence denotes METHODS:
T5 443-517 Sentence denotes Arg1 was ablated in the lung by crossing Arg1 fl/fl and Tie2Cre tg/- mice.
T6 518-632 Sentence denotes OVA sensitization and challenge were conducted, and AHR to methacholine was determined using the Flexivent system.
T7 633-803 Sentence denotes Changes in gene expression, chemokine and cytokine secretion, plasma IgE, and lung histology were quantified using RT-qPCR, ELISA, and immunohistochemistry, respectively.
T8 804-812 Sentence denotes RESULTS:
T9 813-1160 Sentence denotes Arg1 ablation had no influence on the development of OVA-induced AHR, but attenuated OVA-induced increases in expression of Arg2 and Nos2, Slc7a1, Slc7a2, and Slc7a7 (arginine transporters), Il4, Il5 and Il13 (TH2-type cytokines), Ccl2 and Ccl11 (chemokines), Ifng (TH1-type cytokine), Clca3 and Muc5ac (goblet cell markers), and OVA-specific IgE.
T10 1161-1293 Sentence denotes Pulmonary IL-10 protein content increased, but IL-4, IL-5, IL-13, TNFα and IFNγ content, and lung histopathology, were not affected.
T11 1294-1464 Sentence denotes Arg1 elimination also decreased number and tightness of correlations between adaptive changes in lung function and inflammatory parameters in OVA/OVA-treated female mice.
T12 1465-1608 Sentence denotes OVA/OVA-treated female mice mounted a higher OVA-IgE response than males, but the correlation between lung function and inflammation was lower.
T13 1609-1862 Sentence denotes Arg1-deficient OVA/OVA-treated females differed from males in a more pronounced decline of arginine-metabolizing and -transporting genes, higher plasma arginine levels, a smaller OVA-specific IgE response, and no improvement of peripheral lung function.
T14 1863-1874 Sentence denotes CONCLUSION:
T15 1875-2088 Sentence denotes Complete ablation of Arg1 in the lung affects mRNA abundance of arginine-transporting and -metabolizing genes, and pro-inflammatory genes, but not methacholine responsiveness or accumulation of inflammatory cells.

LitCoin-entities-OrganismTaxon-PD

Id Subject Object Predicate Lexical cue db_id
T1 125-129 OrganismTaxon denotes mice NCBItxid:10095|NCBItxid:10088
T3 383-387 OrganismTaxon denotes mice NCBItxid:10095|NCBItxid:10088
T5 512-516 OrganismTaxon denotes mice NCBItxid:10095|NCBItxid:10088
T7 1459-1463 OrganismTaxon denotes mice NCBItxid:10095|NCBItxid:10088
T9 1488-1492 OrganismTaxon denotes mice NCBItxid:10095|NCBItxid:10088

LitCoin-sentences

Id Subject Object Predicate Lexical cue
T1 0-130 Sentence denotes Arginase 1 deletion in myeloid cells affects the inflammatory response in allergic asthma, but not lung mechanics, in female mice.
T2 131-241 Sentence denotes BACKGROUND: (Over-)expression of arginase may limit local availability of arginine for nitric oxide synthesis.
T3 242-433 Sentence denotes We investigated the significance of arginase1 (ARG1) for the development of airway hyperresponsiveness (AHR) and lung inflammation in female mice with ovalbumin (OVA)-induced allergic asthma.
T4 434-442 Sentence denotes METHODS:
T5 443-517 Sentence denotes Arg1 was ablated in the lung by crossing Arg1 fl/fl and Tie2Cre tg/- mice.
T6 518-632 Sentence denotes OVA sensitization and challenge were conducted, and AHR to methacholine was determined using the Flexivent system.
T7 633-803 Sentence denotes Changes in gene expression, chemokine and cytokine secretion, plasma IgE, and lung histology were quantified using RT-qPCR, ELISA, and immunohistochemistry, respectively.
T8 804-812 Sentence denotes RESULTS:
T9 813-1160 Sentence denotes Arg1 ablation had no influence on the development of OVA-induced AHR, but attenuated OVA-induced increases in expression of Arg2 and Nos2, Slc7a1, Slc7a2, and Slc7a7 (arginine transporters), Il4, Il5 and Il13 (TH2-type cytokines), Ccl2 and Ccl11 (chemokines), Ifng (TH1-type cytokine), Clca3 and Muc5ac (goblet cell markers), and OVA-specific IgE.
T10 1161-1293 Sentence denotes Pulmonary IL-10 protein content increased, but IL-4, IL-5, IL-13, TNFα and IFNγ content, and lung histopathology, were not affected.
T11 1294-1464 Sentence denotes Arg1 elimination also decreased number and tightness of correlations between adaptive changes in lung function and inflammatory parameters in OVA/OVA-treated female mice.
T12 1465-1608 Sentence denotes OVA/OVA-treated female mice mounted a higher OVA-IgE response than males, but the correlation between lung function and inflammation was lower.
T13 1609-1862 Sentence denotes Arg1-deficient OVA/OVA-treated females differed from males in a more pronounced decline of arginine-metabolizing and -transporting genes, higher plasma arginine levels, a smaller OVA-specific IgE response, and no improvement of peripheral lung function.
T14 1863-1874 Sentence denotes CONCLUSION:
T15 1875-2088 Sentence denotes Complete ablation of Arg1 in the lung affects mRNA abundance of arginine-transporting and -metabolizing genes, and pro-inflammatory genes, but not methacholine responsiveness or accumulation of inflammatory cells.

LitCoin-entities

Id Subject Object Predicate Lexical cue db_id
13503 0-10 GeneOrGeneProduct denotes Arginase 1 NCBIGene:11846
13504 49-61 DiseaseOrPhenotypicFeature denotes inflammatory MESH:D007249
13505 83-89 DiseaseOrPhenotypicFeature denotes asthma MESH:D001249
13506 125-129 OrganismTaxon denotes mice NCBITaxon:10090
13507 164-172 GeneOrGeneProduct denotes arginase NCBIGene:11846
13508 218-230 ChemicalEntity denotes nitric oxide MESH:D009569
13509 278-287 GeneOrGeneProduct denotes arginase1 NCBIGene:11846
13510 289-293 GeneOrGeneProduct denotes ARG1 NCBIGene:11846
13511 355-372 DiseaseOrPhenotypicFeature denotes lung inflammation MESH:D011014
13512 383-387 OrganismTaxon denotes mice NCBITaxon:10090
13513 393-402 GeneOrGeneProduct denotes ovalbumin NCBIGene:66222
13514 404-407 GeneOrGeneProduct denotes OVA NCBIGene:66222
13515 426-432 DiseaseOrPhenotypicFeature denotes asthma MESH:D001249
13516 443-447 GeneOrGeneProduct denotes Arg1 NCBIGene:11846
13517 484-488 GeneOrGeneProduct denotes Arg1 NCBIGene:11846
13518 512-516 OrganismTaxon denotes mice NCBITaxon:10090
13519 518-521 GeneOrGeneProduct denotes OVA NCBIGene:66222
13520 577-589 ChemicalEntity denotes methacholine MESH:D016210
13521 702-705 GeneOrGeneProduct denotes IgE NCBIGene:629822
13522 813-817 GeneOrGeneProduct denotes Arg1 NCBIGene:11846
13523 866-869 GeneOrGeneProduct denotes OVA NCBIGene:66222
13524 898-901 GeneOrGeneProduct denotes OVA NCBIGene:66222
13525 937-941 GeneOrGeneProduct denotes Arg2 NCBIGene:11847
13526 946-950 GeneOrGeneProduct denotes Nos2 NCBIGene:18126
13527 952-958 GeneOrGeneProduct denotes Slc7a1 NCBIGene:11987
13528 960-966 GeneOrGeneProduct denotes Slc7a2 NCBIGene:11988
13529 972-978 GeneOrGeneProduct denotes Slc7a7 NCBIGene:20540
13530 980-1001 GeneOrGeneProduct denotes arginine transporters NCBIGene:11987|NCBIGene:11988|NCBIGene:20540
13531 1004-1007 GeneOrGeneProduct denotes Il4 NCBIGene:16189
13532 1009-1012 GeneOrGeneProduct denotes Il5 NCBIGene:16191
13533 1017-1021 GeneOrGeneProduct denotes Il13 NCBIGene:16163
13534 1023-1041 GeneOrGeneProduct denotes TH2-type cytokines NCBIGene:16163|NCBIGene:16189|NCBIGene:16191
13535 1044-1048 GeneOrGeneProduct denotes Ccl2 NCBIGene:20296
13536 1053-1058 GeneOrGeneProduct denotes Ccl11 NCBIGene:20292
13537 1060-1070 GeneOrGeneProduct denotes chemokines NCBIGene:20292|NCBIGene:20296
13538 1073-1077 GeneOrGeneProduct denotes Ifng NCBIGene:15978
13539 1079-1096 GeneOrGeneProduct denotes TH1-type cytokine NCBIGene:15978
13540 1099-1104 GeneOrGeneProduct denotes Clca3 NCBIGene:23844
13541 1109-1115 GeneOrGeneProduct denotes Muc5ac NCBIGene:17833
13542 1143-1146 GeneOrGeneProduct denotes OVA NCBIGene:66222
13543 1156-1159 GeneOrGeneProduct denotes IgE NCBIGene:629822
13544 1171-1176 GeneOrGeneProduct denotes IL-10 NCBIGene:16153
13545 1208-1212 GeneOrGeneProduct denotes IL-4 NCBIGene:16189
13546 1214-1218 GeneOrGeneProduct denotes IL-5 NCBIGene:16191
13547 1220-1225 GeneOrGeneProduct denotes IL-13 NCBIGene:16163
13548 1227-1231 GeneOrGeneProduct denotes TNFα NCBIGene:21926
13549 1236-1240 GeneOrGeneProduct denotes IFNγ NCBIGene:15978
13550 1294-1298 GeneOrGeneProduct denotes Arg1 NCBIGene:11846
13551 1409-1421 DiseaseOrPhenotypicFeature denotes inflammatory MESH:D007249
13552 1436-1439 GeneOrGeneProduct denotes OVA NCBIGene:66222
13553 1440-1443 GeneOrGeneProduct denotes OVA NCBIGene:66222
13554 1459-1463 OrganismTaxon denotes mice NCBITaxon:10090
13555 1465-1468 GeneOrGeneProduct denotes OVA NCBIGene:66222
13556 1469-1472 GeneOrGeneProduct denotes OVA NCBIGene:66222
13557 1488-1492 OrganismTaxon denotes mice NCBITaxon:10090
13558 1510-1513 GeneOrGeneProduct denotes OVA NCBIGene:66222
13559 1514-1517 GeneOrGeneProduct denotes IgE NCBIGene:629822
13560 1585-1597 DiseaseOrPhenotypicFeature denotes inflammation MESH:D007249
13561 1609-1613 GeneOrGeneProduct denotes Arg1 NCBIGene:11846
13562 1624-1627 GeneOrGeneProduct denotes OVA NCBIGene:66222
13563 1628-1631 GeneOrGeneProduct denotes OVA NCBIGene:66222
13564 1788-1791 GeneOrGeneProduct denotes OVA NCBIGene:66222
13565 1801-1804 GeneOrGeneProduct denotes IgE NCBIGene:629822
13566 1896-1900 GeneOrGeneProduct denotes Arg1 NCBIGene:11846
13567 1994-2006 DiseaseOrPhenotypicFeature denotes inflammatory MESH:D007249
13568 2022-2034 ChemicalEntity denotes methacholine MESH:D016210
13569 2069-2081 DiseaseOrPhenotypicFeature denotes inflammatory MESH:D007249

LitCoin_Mondo

Id Subject Object Predicate Lexical cue mondo_id
T1 74-89 DiseaseOrPhenotypicFeature denotes allergic asthma 0004784
T2 83-89 DiseaseOrPhenotypicFeature denotes asthma 0004979
T3 417-432 DiseaseOrPhenotypicFeature denotes allergic asthma 0004784
T4 426-432 DiseaseOrPhenotypicFeature denotes asthma 0004979
T5 1875-1883 DiseaseOrPhenotypicFeature denotes Complete 0700063

LitCoin-SeqVar

Id Subject Object Predicate Lexical cue
T1 499-506 SequenceVariant denotes Tie2Cre

LitCoin-GeneOrGeneProduct-v0

Id Subject Object Predicate Lexical cue
T1 0-10 GeneOrGeneProduct denotes Arginase 1
T2 31-36 GeneOrGeneProduct denotes cells
T3 99-103 GeneOrGeneProduct denotes lung
T4 125-129 GeneOrGeneProduct denotes mice
T5 164-172 GeneOrGeneProduct denotes arginase
T6 177-182 GeneOrGeneProduct denotes limit
T7 189-201 GeneOrGeneProduct denotes availability
T8 289-293 GeneOrGeneProduct denotes ARG1
T9 355-359 GeneOrGeneProduct denotes lung
T10 383-387 GeneOrGeneProduct denotes mice
T11 393-402 GeneOrGeneProduct denotes ovalbumin
T12 404-407 GeneOrGeneProduct denotes OVA
T13 409-416 GeneOrGeneProduct denotes induced
T14 434-441 GeneOrGeneProduct denotes METHODS
T15 443-447 GeneOrGeneProduct denotes Arg1
T16 467-471 GeneOrGeneProduct denotes lung
T17 484-488 GeneOrGeneProduct denotes Arg1
T18 489-494 GeneOrGeneProduct denotes fl/fl
T19 512-516 GeneOrGeneProduct denotes mice
T20 518-521 GeneOrGeneProduct denotes OVA
T21 594-604 GeneOrGeneProduct denotes determined
T22 661-670 GeneOrGeneProduct denotes chemokine
T23 684-693 GeneOrGeneProduct denotes secretion
T24 711-715 GeneOrGeneProduct denotes lung
T25 813-817 GeneOrGeneProduct denotes Arg1
T26 866-869 GeneOrGeneProduct denotes OVA
T27 870-877 GeneOrGeneProduct denotes induced
T28 887-897 GeneOrGeneProduct denotes attenuated
T29 898-901 GeneOrGeneProduct denotes OVA
T30 902-909 GeneOrGeneProduct denotes induced
T31 937-941 GeneOrGeneProduct denotes Arg2
T32 946-950 GeneOrGeneProduct denotes Nos2
T33 952-958 GeneOrGeneProduct denotes Slc7a1
T34 960-966 GeneOrGeneProduct denotes Slc7a2
T35 972-978 GeneOrGeneProduct denotes Slc7a7
T36 980-1001 GeneOrGeneProduct denotes arginine transporters
T37 1004-1007 GeneOrGeneProduct denotes Il4
T38 1009-1012 GeneOrGeneProduct denotes Il5
T39 1017-1021 GeneOrGeneProduct denotes Il13
T40 1044-1048 GeneOrGeneProduct denotes Ccl2
T41 1053-1058 GeneOrGeneProduct denotes Ccl11
T42 1060-1070 GeneOrGeneProduct denotes chemokines
T43 1073-1077 GeneOrGeneProduct denotes Ifng
T44 1079-1082 GeneOrGeneProduct denotes TH1
T45 1099-1104 GeneOrGeneProduct denotes Clca3
T46 1109-1115 GeneOrGeneProduct denotes Muc5ac
T47 1117-1123 GeneOrGeneProduct denotes goblet
T48 1124-1128 GeneOrGeneProduct denotes cell
T49 1143-1146 GeneOrGeneProduct denotes OVA
T50 1171-1176 GeneOrGeneProduct denotes IL-10
T51 1177-1184 GeneOrGeneProduct denotes protein
T52 1208-1212 GeneOrGeneProduct denotes IL-4
T53 1214-1218 GeneOrGeneProduct denotes IL-5
T54 1220-1225 GeneOrGeneProduct denotes IL-13
T55 1236-1239 GeneOrGeneProduct denotes IFN
T56 1254-1258 GeneOrGeneProduct denotes lung
T57 1294-1298 GeneOrGeneProduct denotes Arg1
T58 1391-1395 GeneOrGeneProduct denotes lung
T59 1436-1439 GeneOrGeneProduct denotes OVA
T60 1440-1443 GeneOrGeneProduct denotes OVA
T61 1459-1463 GeneOrGeneProduct denotes mice
T62 1465-1468 GeneOrGeneProduct denotes OVA
T63 1469-1472 GeneOrGeneProduct denotes OVA
T64 1488-1492 GeneOrGeneProduct denotes mice
T65 1510-1513 GeneOrGeneProduct denotes OVA
T66 1514-1526 GeneOrGeneProduct denotes IgE response
T67 1532-1537 GeneOrGeneProduct denotes males
T68 1567-1571 GeneOrGeneProduct denotes lung
T69 1609-1613 GeneOrGeneProduct denotes Arg1
T70 1624-1627 GeneOrGeneProduct denotes OVA
T71 1628-1631 GeneOrGeneProduct denotes OVA
T72 1662-1667 GeneOrGeneProduct denotes males
T73 1727-1739 GeneOrGeneProduct denotes transporting
T74 1780-1787 GeneOrGeneProduct denotes smaller
T75 1788-1791 GeneOrGeneProduct denotes OVA
T76 1801-1813 GeneOrGeneProduct denotes IgE response
T77 1848-1852 GeneOrGeneProduct denotes lung
T78 1896-1900 GeneOrGeneProduct denotes Arg1
T79 1908-1912 GeneOrGeneProduct denotes lung
T80 1921-1925 GeneOrGeneProduct denotes mRNA
T81 1939-1960 GeneOrGeneProduct denotes arginine-transporting
T82 1990-1993 GeneOrGeneProduct denotes pro
T83 2082-2087 GeneOrGeneProduct denotes cells

LitCoin-GeneOrGeneProduct-v2

Id Subject Object Predicate Lexical cue
T1 0-10 GeneOrGeneProduct denotes Arginase 1
T2 164-172 GeneOrGeneProduct denotes arginase
T3 289-293 GeneOrGeneProduct denotes ARG1
T4 393-402 GeneOrGeneProduct denotes ovalbumin
T5 404-407 GeneOrGeneProduct denotes OVA
T6 443-447 GeneOrGeneProduct denotes Arg1
T7 484-488 GeneOrGeneProduct denotes Arg1
T8 489-494 GeneOrGeneProduct denotes fl/fl
T9 518-521 GeneOrGeneProduct denotes OVA
T10 661-670 GeneOrGeneProduct denotes chemokine
T11 813-817 GeneOrGeneProduct denotes Arg1
T12 866-869 GeneOrGeneProduct denotes OVA
T13 887-897 GeneOrGeneProduct denotes attenuated
T14 898-901 GeneOrGeneProduct denotes OVA
T15 937-941 GeneOrGeneProduct denotes Arg2
T16 946-950 GeneOrGeneProduct denotes Nos2
T17 952-958 GeneOrGeneProduct denotes Slc7a1
T18 960-966 GeneOrGeneProduct denotes Slc7a2
T19 972-978 GeneOrGeneProduct denotes Slc7a7
T20 980-1001 GeneOrGeneProduct denotes arginine transporters
T21 1004-1007 GeneOrGeneProduct denotes Il4
T22 1009-1012 GeneOrGeneProduct denotes Il5
T23 1017-1021 GeneOrGeneProduct denotes Il13
T24 1044-1048 GeneOrGeneProduct denotes Ccl2
T25 1053-1058 GeneOrGeneProduct denotes Ccl11
T26 1060-1070 GeneOrGeneProduct denotes chemokines
T27 1073-1077 GeneOrGeneProduct denotes Ifng
T28 1079-1082 GeneOrGeneProduct denotes TH1
T29 1099-1104 GeneOrGeneProduct denotes Clca3
T30 1109-1115 GeneOrGeneProduct denotes Muc5ac
T31 1117-1123 GeneOrGeneProduct denotes goblet
T32 1124-1128 GeneOrGeneProduct denotes cell
T33 1143-1146 GeneOrGeneProduct denotes OVA
T34 1171-1176 GeneOrGeneProduct denotes IL-10
T35 1177-1184 GeneOrGeneProduct denotes protein
T36 1208-1212 GeneOrGeneProduct denotes IL-4
T37 1214-1218 GeneOrGeneProduct denotes IL-5
T38 1220-1225 GeneOrGeneProduct denotes IL-13
T39 1294-1298 GeneOrGeneProduct denotes Arg1
T40 1436-1439 GeneOrGeneProduct denotes OVA
T41 1440-1443 GeneOrGeneProduct denotes OVA
T42 1465-1468 GeneOrGeneProduct denotes OVA
T43 1469-1472 GeneOrGeneProduct denotes OVA
T44 1510-1513 GeneOrGeneProduct denotes OVA
T45 1609-1613 GeneOrGeneProduct denotes Arg1
T46 1624-1627 GeneOrGeneProduct denotes OVA
T47 1628-1631 GeneOrGeneProduct denotes OVA
T48 1780-1787 GeneOrGeneProduct denotes smaller
T49 1788-1791 GeneOrGeneProduct denotes OVA
T50 1896-1900 GeneOrGeneProduct denotes Arg1
T51 1921-1925 GeneOrGeneProduct denotes mRNA

LitCoin-Disease-MeSH

Id Subject Object Predicate Lexical cue originalLabel
T1 49-61 DiseaseOrPhenotypicFeature denotes inflammatory DISEASE
T2 83-89 DiseaseOrPhenotypicFeature denotes asthma D001249
T3 318-344 DiseaseOrPhenotypicFeature denotes airway hyperresponsiveness D012130
T4 346-349 DiseaseOrPhenotypicFeature denotes AHR D012130
T5 355-372 DiseaseOrPhenotypicFeature denotes lung inflammation D011014
T6 426-432 DiseaseOrPhenotypicFeature denotes asthma D001249
T7 570-573 DiseaseOrPhenotypicFeature denotes AHR D012130
T8 878-881 DiseaseOrPhenotypicFeature denotes AHR D012130
T9 1409-1421 DiseaseOrPhenotypicFeature denotes inflammatory DISEASE
T10 1585-1597 DiseaseOrPhenotypicFeature denotes inflammation D007249
T11 1609-1623 DiseaseOrPhenotypicFeature denotes Arg1-deficient D020162
T12 1994-2006 DiseaseOrPhenotypicFeature denotes inflammatory DISEASE
T13 2069-2081 DiseaseOrPhenotypicFeature denotes inflammatory DISEASE

LitCoin-GeneOrGeneProduct-v3

Id Subject Object Predicate Lexical cue
T1 0-10 GeneOrGeneProduct denotes Arginase 1
T2 164-172 GeneOrGeneProduct denotes arginase
T3 289-293 GeneOrGeneProduct denotes ARG1
T4 393-402 GeneOrGeneProduct denotes ovalbumin
T5 404-407 GeneOrGeneProduct denotes OVA
T6 443-447 GeneOrGeneProduct denotes Arg1
T7 484-488 GeneOrGeneProduct denotes Arg1
T8 489-494 GeneOrGeneProduct denotes fl/fl
T9 518-521 GeneOrGeneProduct denotes OVA
T10 661-670 GeneOrGeneProduct denotes chemokine
T11 813-817 GeneOrGeneProduct denotes Arg1
T12 866-869 GeneOrGeneProduct denotes OVA
T13 898-901 GeneOrGeneProduct denotes OVA
T14 937-941 GeneOrGeneProduct denotes Arg2
T15 946-950 GeneOrGeneProduct denotes Nos2
T16 952-958 GeneOrGeneProduct denotes Slc7a1
T17 960-966 GeneOrGeneProduct denotes Slc7a2
T18 972-978 GeneOrGeneProduct denotes Slc7a7
T19 980-1001 GeneOrGeneProduct denotes arginine transporters
T20 1004-1007 GeneOrGeneProduct denotes Il4
T21 1009-1012 GeneOrGeneProduct denotes Il5
T22 1017-1021 GeneOrGeneProduct denotes Il13
T23 1044-1048 GeneOrGeneProduct denotes Ccl2
T24 1053-1058 GeneOrGeneProduct denotes Ccl11
T25 1060-1070 GeneOrGeneProduct denotes chemokines
T26 1073-1077 GeneOrGeneProduct denotes Ifng
T27 1079-1082 GeneOrGeneProduct denotes TH1
T28 1099-1104 GeneOrGeneProduct denotes Clca3
T29 1109-1115 GeneOrGeneProduct denotes Muc5ac
T30 1117-1123 GeneOrGeneProduct denotes goblet
T31 1143-1146 GeneOrGeneProduct denotes OVA
T32 1171-1176 GeneOrGeneProduct denotes IL-10
T33 1177-1192 GeneOrGeneProduct denotes protein content
T34 1208-1212 GeneOrGeneProduct denotes IL-4
T35 1214-1218 GeneOrGeneProduct denotes IL-5
T36 1220-1225 GeneOrGeneProduct denotes IL-13
T37 1236-1240 GeneOrGeneProduct denotes IFNγ
T38 1294-1298 GeneOrGeneProduct denotes Arg1
T39 1436-1439 GeneOrGeneProduct denotes OVA
T40 1440-1443 GeneOrGeneProduct denotes OVA
T41 1465-1468 GeneOrGeneProduct denotes OVA
T42 1469-1472 GeneOrGeneProduct denotes OVA
T43 1510-1513 GeneOrGeneProduct denotes OVA
T44 1609-1613 GeneOrGeneProduct denotes Arg1
T45 1624-1627 GeneOrGeneProduct denotes OVA
T46 1628-1631 GeneOrGeneProduct denotes OVA
T47 1788-1791 GeneOrGeneProduct denotes OVA
T48 1896-1900 GeneOrGeneProduct denotes Arg1

LitCoin_Mondo_095

Id Subject Object Predicate Lexical cue mondo_id
T1 74-89 DiseaseOrPhenotypicFeature denotes allergic asthma 0004784
T2 99-103 DiseaseOrPhenotypicFeature denotes lung 0021117
T3 355-359 DiseaseOrPhenotypicFeature denotes lung 0021117
T4 417-432 DiseaseOrPhenotypicFeature denotes allergic asthma 0004784
T5 467-471 DiseaseOrPhenotypicFeature denotes lung 0021117
T6 711-715 DiseaseOrPhenotypicFeature denotes lung 0021117
T7 1254-1258 DiseaseOrPhenotypicFeature denotes lung 0021117
T8 1391-1395 DiseaseOrPhenotypicFeature denotes lung 0021117
T9 1567-1571 DiseaseOrPhenotypicFeature denotes lung 0021117
T10 1848-1852 DiseaseOrPhenotypicFeature denotes lung 0021117
T11 1908-1912 DiseaseOrPhenotypicFeature denotes lung 0021117

LitCoin-MeSH-Disease-2

Id Subject Object Predicate Lexical cue ID:
T1 49-61 DiseaseOrPhenotypicFeature denotes inflammatory DISEASE
T2 83-89 DiseaseOrPhenotypicFeature denotes asthma D001249
T3 318-344 DiseaseOrPhenotypicFeature denotes airway hyperresponsiveness D012130
T4 346-349 DiseaseOrPhenotypicFeature denotes AHR D012130
T5 355-372 DiseaseOrPhenotypicFeature denotes lung inflammation D011014
T6 426-432 DiseaseOrPhenotypicFeature denotes asthma D001249
T7 570-573 DiseaseOrPhenotypicFeature denotes AHR D012130
T8 878-881 DiseaseOrPhenotypicFeature denotes AHR D012130
T9 1409-1421 DiseaseOrPhenotypicFeature denotes inflammatory DISEASE
T10 1585-1597 DiseaseOrPhenotypicFeature denotes inflammation DISEASE|D007249
T12 1994-2006 DiseaseOrPhenotypicFeature denotes inflammatory DISEASE
T13 2069-2081 DiseaseOrPhenotypicFeature denotes inflammatory DISEASE

LitCoin-MONDO_bioort2019

Id Subject Object Predicate Lexical cue #label
T1 83-89 DiseaseOrPhenotypicFeature denotes asthma D001249
T2 355-372 DiseaseOrPhenotypicFeature denotes lung inflammation D011014
T3 426-432 DiseaseOrPhenotypicFeature denotes asthma D001249
T4 1585-1597 DiseaseOrPhenotypicFeature denotes inflammation D007249
T5 1990-2006 DiseaseOrPhenotypicFeature denotes pro-inflammatory DISEASE

LitCoin-NCBITaxon-2

Id Subject Object Predicate Lexical cue
T1 125-129 OrganismTaxon denotes mice
T2 383-387 OrganismTaxon denotes mice
T3 512-516 OrganismTaxon denotes mice
T4 1459-1463 OrganismTaxon denotes mice
T5 1488-1492 OrganismTaxon denotes mice

LitCoin-Chemical-MeSH-CHEBI

Id Subject Object Predicate Lexical cue ID:
T1 0-8 ChemicalEntity denotes Arginase D001119
T2 164-172 ChemicalEntity denotes arginase D001119
T3 205-213 ChemicalEntity denotes arginine http://purl.obolibrary.org/obo/CHEBI_32696|http://purl.obolibrary.org/obo/CHEBI_29016|http://purl.obolibrary.org/obo/CHEBI_16467
T6 218-230 ChemicalEntity denotes nitric oxide D009569|http://purl.obolibrary.org/obo/CHEBI_16480
T8 577-589 ChemicalEntity denotes methacholine D016210|http://purl.obolibrary.org/obo/CHEBI_6804
T10 980-988 ChemicalEntity denotes arginine http://purl.obolibrary.org/obo/CHEBI_32696|http://purl.obolibrary.org/obo/CHEBI_29016|http://purl.obolibrary.org/obo/CHEBI_16467
T13 1700-1708 ChemicalEntity denotes arginine http://purl.obolibrary.org/obo/CHEBI_32696|http://purl.obolibrary.org/obo/CHEBI_29016|http://purl.obolibrary.org/obo/CHEBI_16467
T16 1761-1769 ChemicalEntity denotes arginine http://purl.obolibrary.org/obo/CHEBI_32696|http://purl.obolibrary.org/obo/CHEBI_29016|http://purl.obolibrary.org/obo/CHEBI_16467
T19 1939-1947 ChemicalEntity denotes arginine http://purl.obolibrary.org/obo/CHEBI_32696|http://purl.obolibrary.org/obo/CHEBI_29016|http://purl.obolibrary.org/obo/CHEBI_16467
T22 2022-2034 ChemicalEntity denotes methacholine D016210|http://purl.obolibrary.org/obo/CHEBI_6804

LitCoin-training-merged

Id Subject Object Predicate Lexical cue #label ID:
T22 2022-2034 ChemicalEntity denotes methacholine http://purl.obolibrary.org/obo/CHEBI_6804|D016210
T19 1939-1947 ChemicalEntity denotes arginine http://purl.obolibrary.org/obo/CHEBI_16467|http://purl.obolibrary.org/obo/CHEBI_29016|http://purl.obolibrary.org/obo/CHEBI_32696
T16 1761-1769 ChemicalEntity denotes arginine http://purl.obolibrary.org/obo/CHEBI_16467|http://purl.obolibrary.org/obo/CHEBI_29016|http://purl.obolibrary.org/obo/CHEBI_32696
T13 1700-1708 ChemicalEntity denotes arginine http://purl.obolibrary.org/obo/CHEBI_16467|http://purl.obolibrary.org/obo/CHEBI_29016|http://purl.obolibrary.org/obo/CHEBI_32696
T10 980-988 ChemicalEntity denotes arginine http://purl.obolibrary.org/obo/CHEBI_16467|http://purl.obolibrary.org/obo/CHEBI_29016|http://purl.obolibrary.org/obo/CHEBI_32696
T8 577-589 ChemicalEntity denotes methacholine http://purl.obolibrary.org/obo/CHEBI_6804|D016210
T6 218-230 ChemicalEntity denotes nitric oxide http://purl.obolibrary.org/obo/CHEBI_16480|D009569
T3 205-213 ChemicalEntity denotes arginine http://purl.obolibrary.org/obo/CHEBI_16467|http://purl.obolibrary.org/obo/CHEBI_29016|http://purl.obolibrary.org/obo/CHEBI_32696
T2 164-172 ChemicalEntity denotes arginase D001119
T1 0-8 ChemicalEntity denotes Arginase D001119
T48 1896-1900 GeneOrGeneProduct denotes Arg1
T47 1788-1791 GeneOrGeneProduct denotes OVA
T46 1628-1631 GeneOrGeneProduct denotes OVA
T45 1624-1627 GeneOrGeneProduct denotes OVA
T44 1609-1613 GeneOrGeneProduct denotes Arg1
T43 1510-1513 GeneOrGeneProduct denotes OVA
T42 1469-1472 GeneOrGeneProduct denotes OVA
T41 1465-1468 GeneOrGeneProduct denotes OVA
T40 1440-1443 GeneOrGeneProduct denotes OVA
T39 1436-1439 GeneOrGeneProduct denotes OVA
T38 1294-1298 GeneOrGeneProduct denotes Arg1
T37 1236-1240 GeneOrGeneProduct denotes IFNγ
T36 1220-1225 GeneOrGeneProduct denotes IL-13
T35 1214-1218 GeneOrGeneProduct denotes IL-5
T34 1208-1212 GeneOrGeneProduct denotes IL-4
T33 1177-1192 GeneOrGeneProduct denotes protein content
T32 1171-1176 GeneOrGeneProduct denotes IL-10
T31 1143-1146 GeneOrGeneProduct denotes OVA
T30 1117-1123 GeneOrGeneProduct denotes goblet
T29 1109-1115 GeneOrGeneProduct denotes Muc5ac
T28 1099-1104 GeneOrGeneProduct denotes Clca3
T27 1079-1082 GeneOrGeneProduct denotes TH1
T26 1073-1077 GeneOrGeneProduct denotes Ifng
T25 1060-1070 GeneOrGeneProduct denotes chemokines
T24 1053-1058 GeneOrGeneProduct denotes Ccl11
T23 1044-1048 GeneOrGeneProduct denotes Ccl2
T93345 1017-1021 GeneOrGeneProduct denotes Il13
T21 1009-1012 GeneOrGeneProduct denotes Il5
T20 1004-1007 GeneOrGeneProduct denotes Il4
T33431 980-1001 GeneOrGeneProduct denotes arginine transporters
T18 972-978 GeneOrGeneProduct denotes Slc7a7
T17 960-966 GeneOrGeneProduct denotes Slc7a2
T77907 952-958 GeneOrGeneProduct denotes Slc7a1
T15 946-950 GeneOrGeneProduct denotes Nos2
T14 937-941 GeneOrGeneProduct denotes Arg2
T51270 898-901 GeneOrGeneProduct denotes OVA
T12 866-869 GeneOrGeneProduct denotes OVA
T11 813-817 GeneOrGeneProduct denotes Arg1
T85745 661-670 GeneOrGeneProduct denotes chemokine
T9 518-521 GeneOrGeneProduct denotes OVA
T73621 489-494 GeneOrGeneProduct denotes fl/fl
T7 484-488 GeneOrGeneProduct denotes Arg1
T84146 443-447 GeneOrGeneProduct denotes Arg1
T5 404-407 GeneOrGeneProduct denotes OVA
T4 393-402 GeneOrGeneProduct denotes ovalbumin
T79761 289-293 GeneOrGeneProduct denotes ARG1
T48297 164-172 GeneOrGeneProduct denotes arginase
T59003 0-10 GeneOrGeneProduct denotes Arginase 1
T42346 1990-2006 DiseaseOrPhenotypicFeature denotes pro-inflammatory DISEASE
T26663 1585-1597 DiseaseOrPhenotypicFeature denotes inflammation D007249
T36153 426-432 DiseaseOrPhenotypicFeature denotes asthma D001249
T26153 355-372 DiseaseOrPhenotypicFeature denotes lung inflammation D011014
T35474 83-89 DiseaseOrPhenotypicFeature denotes asthma D001249
T64557 1488-1492 OrganismTaxon denotes mice
T7255 1459-1463 OrganismTaxon denotes mice
T33190 512-516 OrganismTaxon denotes mice
T73347 383-387 OrganismTaxon denotes mice
T78604 125-129 OrganismTaxon denotes mice
T45361 499-506 SequenceVariant denotes Tie2Cre