PubMed:29026098
Annnotations
CL-cell
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 54-76 | Cell | denotes | Pluripotent Stem Cells | http://purl.obolibrary.org/obo/CL:0002248 |
| T2 | 160-181 | Cell | denotes | pluripotent stem cell | http://purl.obolibrary.org/obo/CL:0002248 |
| T3 | 172-181 | Cell | denotes | stem cell | http://purl.obolibrary.org/obo/CL:0000034 |
| T4 | 183-187 | Cell | denotes | hPSC | http://purl.obolibrary.org/obo/CL:0002195 |
| T5 | 322-341 | Cell | denotes | embryonic stem cell | http://purl.obolibrary.org/obo/CL:0002322 |
| T6 | 332-341 | Cell | denotes | stem cell | http://purl.obolibrary.org/obo/CL:0000034 |
| T7 | 373-394 | Cell | denotes | pluripotent stem cell | http://purl.obolibrary.org/obo/CL:0002248 |
| T8 | 385-394 | Cell | denotes | stem cell | http://purl.obolibrary.org/obo/CL:0000034 |
| T9 | 413-423 | Cell | denotes | hepatocyte | http://purl.obolibrary.org/obo/CL:0000182 |
| T10 | 429-442 | Cell | denotes | cardiomyocyte | http://purl.obolibrary.org/obo/CL:0000746 |
| T11 | 525-529 | Cell | denotes | hPSC | http://purl.obolibrary.org/obo/CL:0002195 |
| T12 | 568-578 | Cell | denotes | hepatocyte | http://purl.obolibrary.org/obo/CL:0000182 |
| T13 | 630-643 | Cell | denotes | cardiomyocyte | http://purl.obolibrary.org/obo/CL:0000746 |
| T14 | 894-898 | Cell | denotes | hPSC | http://purl.obolibrary.org/obo/CL:0002195 |
| T15 | 1070-1074 | Cell | denotes | hPSC | http://purl.obolibrary.org/obo/CL:0002195 |
| T16 | 1245-1249 | Cell | denotes | hPSC | http://purl.obolibrary.org/obo/CL:0002195 |
| T17 | 1318-1322 | Cell | denotes | hPSC | http://purl.obolibrary.org/obo/CL:0002195 |
| T18 | 1490-1499 | Cell | denotes | stem cell | http://purl.obolibrary.org/obo/CL:0000034 |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 14-19 | Body_part | denotes | Blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
| T3 | 66-76 | Body_part | denotes | Stem Cells | http://purl.obolibrary.org/obo/MAT_0000185 |
| T4 | 172-181 | Body_part | denotes | stem cell | http://purl.obolibrary.org/obo/MAT_0000185 |
| T5 | 332-341 | Body_part | denotes | stem cell | http://purl.obolibrary.org/obo/MAT_0000185 |
| T6 | 385-394 | Body_part | denotes | stem cell | http://purl.obolibrary.org/obo/MAT_0000185 |
| T7 | 774-779 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
| T9 | 906-911 | Body_part | denotes | Blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
| T11 | 1087-1092 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
| T13 | 1490-1499 | Body_part | denotes | stem cell | http://purl.obolibrary.org/obo/MAT_0000185 |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 808-814 | Glycan | denotes | SSEA-3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G25129BT |
| T2 | 815-821 | Glycan | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84263XI |
GlyCosmos-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 808-814 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-3 | http://www.glycoepitope.jp/epitopes/EP0039 |
| T2 | 815-821 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-4 | http://www.glycoepitope.jp/epitopes/EP0044 |
GlyCosmos15-NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 48-53 | OrganismTaxon | denotes | Human | 9606 |
| T2 | 154-159 | OrganismTaxon | denotes | human | 9606 |
| T3 | 316-321 | OrganismTaxon | denotes | human | 9606 |
| T4 | 367-372 | OrganismTaxon | denotes | human | 9606 |
GlyCosmos15-CL
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 54-76 | Cell | denotes | Pluripotent Stem Cells | http://purl.obolibrary.org/obo/CL:0002248 |
| T2 | 160-181 | Cell | denotes | pluripotent stem cell | http://purl.obolibrary.org/obo/CL:0002248 |
| T3 | 172-181 | Cell | denotes | stem cell | http://purl.obolibrary.org/obo/CL:0000034 |
| T4 | 183-187 | Cell | denotes | hPSC | http://purl.obolibrary.org/obo/CL:0002195 |
| T5 | 322-341 | Cell | denotes | embryonic stem cell | http://purl.obolibrary.org/obo/CL:0002322 |
| T6 | 332-341 | Cell | denotes | stem cell | http://purl.obolibrary.org/obo/CL:0000034 |
| T7 | 373-394 | Cell | denotes | pluripotent stem cell | http://purl.obolibrary.org/obo/CL:0002248 |
| T8 | 385-394 | Cell | denotes | stem cell | http://purl.obolibrary.org/obo/CL:0000034 |
| T9 | 413-423 | Cell | denotes | hepatocyte | http://purl.obolibrary.org/obo/CL:0000182 |
| T10 | 429-442 | Cell | denotes | cardiomyocyte | http://purl.obolibrary.org/obo/CL:0000746 |
| T11 | 525-529 | Cell | denotes | hPSC | http://purl.obolibrary.org/obo/CL:0002195 |
| T12 | 568-578 | Cell | denotes | hepatocyte | http://purl.obolibrary.org/obo/CL:0000182 |
| T13 | 630-643 | Cell | denotes | cardiomyocyte | http://purl.obolibrary.org/obo/CL:0000746 |
| T14 | 894-898 | Cell | denotes | hPSC | http://purl.obolibrary.org/obo/CL:0002195 |
| T15 | 1070-1074 | Cell | denotes | hPSC | http://purl.obolibrary.org/obo/CL:0002195 |
| T16 | 1245-1249 | Cell | denotes | hPSC | http://purl.obolibrary.org/obo/CL:0002195 |
| T17 | 1318-1322 | Cell | denotes | hPSC | http://purl.obolibrary.org/obo/CL:0002195 |
| T18 | 1490-1499 | Cell | denotes | stem cell | http://purl.obolibrary.org/obo/CL:0000034 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 14-19 | Body_part | denotes | Blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T2 | 54-76 | Body_part | denotes | Pluripotent Stem Cells | http://purl.obolibrary.org/obo/CL_0002248 |
| T3 | 160-181 | Body_part | denotes | pluripotent stem cell | http://purl.obolibrary.org/obo/CL_0002248 |
| T4 | 251-257 | Body_part | denotes | tissue | http://purl.obolibrary.org/obo/UBERON_0000479 |
| T5 | 332-341 | Body_part | denotes | stem cell | http://purl.obolibrary.org/obo/CL_0000034 |
| T6 | 373-394 | Body_part | denotes | pluripotent stem cell | http://purl.obolibrary.org/obo/CL_0002248 |
| T7 | 413-423 | Body_part | denotes | hepatocyte | http://purl.obolibrary.org/obo/CL_0000182 |
| T8 | 429-442 | Body_part | denotes | cardiomyocyte | http://purl.obolibrary.org/obo/CL_0000746 |
| T9 | 568-578 | Body_part | denotes | hepatocyte | http://purl.obolibrary.org/obo/CL_0000182 |
| T10 | 630-643 | Body_part | denotes | cardiomyocyte | http://purl.obolibrary.org/obo/CL_0000746 |
| T11 | 774-779 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T12 | 906-911 | Body_part | denotes | Blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T13 | 1087-1092 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T14 | 1263-1269 | Body_part | denotes | tissue | http://purl.obolibrary.org/obo/UBERON_0000479 |
| T15 | 1424-1430 | Body_part | denotes | tissue | http://purl.obolibrary.org/obo/UBERON_0000479 |
| T16 | 1490-1499 | Body_part | denotes | stem cell | http://purl.obolibrary.org/obo/CL_0000034 |
GlyCosmos15-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 14-19 | Body_part | denotes | Blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
| T3 | 66-76 | Body_part | denotes | Stem Cells | http://purl.obolibrary.org/obo/MAT_0000185 |
| T4 | 172-181 | Body_part | denotes | stem cell | http://purl.obolibrary.org/obo/MAT_0000185 |
| T5 | 332-341 | Body_part | denotes | stem cell | http://purl.obolibrary.org/obo/MAT_0000185 |
| T6 | 385-394 | Body_part | denotes | stem cell | http://purl.obolibrary.org/obo/MAT_0000185 |
| T7 | 774-779 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
| T9 | 906-911 | Body_part | denotes | Blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
| T11 | 1087-1092 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
| T13 | 1490-1499 | Body_part | denotes | stem cell | http://purl.obolibrary.org/obo/MAT_0000185 |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-99 | Sentence | denotes | HLA and Histo-Blood Group Antigen Expression in Human Pluripotent Stem Cells and their Derivatives. |
| T2 | 100-272 | Sentence | denotes | One prerequisite for a successful clinical outcome of human pluripotent stem cell (hPSC) based therapies is immune compatibility between grafted cells/tissue and recipient. |
| T3 | 273-479 | Sentence | denotes | This study explores immune determinants of human embryonic stem cell lines (hESC) and induced human pluripotent stem cell (hiPSC) lines and hepatocyte- and cardiomyocyte-like cells derived from these cells. |
| T4 | 480-687 | Sentence | denotes | HLA class I was expressed on all pluripotent hPSC lines which upon differentiation into hepatocyte-like cells was considerably reduced in contrast to cardiomyocyte-like cells which retained class I antigens. |
| T5 | 688-767 | Sentence | denotes | No HLA class II antigens were found in the pluripotent or differentiated cells. |
| T6 | 768-905 | Sentence | denotes | Histo-blood group carbohydrate antigens SSEA-3/SSEA-4/SSEA-5, Globo H, A, Lex/Ley and sialyl-lactotetra were expressed on all hPSC lines. |
| T7 | 906-980 | Sentence | denotes | Blood group AB(O)H antigen expression was in accordance with ABO genotype. |
| T8 | 981-1212 | Sentence | denotes | Interestingly, only a subpopulation of A1O1 cells expressed A. During differentiation of hPSC, some histo-blood group antigens showed congruent alteration patterns while expression of other antigens differed between the cell lines. |
| T9 | 1213-1302 | Sentence | denotes | No systematic difference in the hPSC cell surface tissue antigen expression was detected. |
| T10 | 1303-1410 | Sentence | denotes | In conclusion, hPSC and their derivatives express cell surface antigens that may cause an immune rejection. |
| T11 | 1411-1535 | Sentence | denotes | Furthermore, tissue antigen expression must be established for each individual stem cell line prior to clinical application. |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 808-814 | Glycan | denotes | SSEA-3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G25129BT |
| T2 | 815-821 | Glycan | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84263XI |
GlyCosmos15-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 808-814 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-3 | http://www.glycoepitope.jp/epitopes/EP0039 |
| T2 | 815-821 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-4 | http://www.glycoepitope.jp/epitopes/EP0044 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 48-53 | OrganismTaxon | denotes | Human | 9606 |
| T2 | 154-159 | OrganismTaxon | denotes | human | 9606 |
| T3 | 316-321 | OrganismTaxon | denotes | human | 9606 |
| T4 | 367-372 | OrganismTaxon | denotes | human | 9606 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 14-19 | Body_part | denotes | Blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T2 | 54-76 | Body_part | denotes | Pluripotent Stem Cells | http://purl.obolibrary.org/obo/CL_0002248 |
| T3 | 160-181 | Body_part | denotes | pluripotent stem cell | http://purl.obolibrary.org/obo/CL_0002248 |
| T4 | 251-257 | Body_part | denotes | tissue | http://purl.obolibrary.org/obo/UBERON_0000479 |
| T5 | 332-341 | Body_part | denotes | stem cell | http://purl.obolibrary.org/obo/CL_0000034 |
| T6 | 373-394 | Body_part | denotes | pluripotent stem cell | http://purl.obolibrary.org/obo/CL_0002248 |
| T7 | 413-423 | Body_part | denotes | hepatocyte | http://purl.obolibrary.org/obo/CL_0000182 |
| T8 | 429-442 | Body_part | denotes | cardiomyocyte | http://purl.obolibrary.org/obo/CL_0000746 |
| T9 | 568-578 | Body_part | denotes | hepatocyte | http://purl.obolibrary.org/obo/CL_0000182 |
| T10 | 630-643 | Body_part | denotes | cardiomyocyte | http://purl.obolibrary.org/obo/CL_0000746 |
| T11 | 774-779 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T12 | 906-911 | Body_part | denotes | Blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T13 | 1087-1092 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T14 | 1263-1269 | Body_part | denotes | tissue | http://purl.obolibrary.org/obo/UBERON_0000479 |
| T15 | 1424-1430 | Body_part | denotes | tissue | http://purl.obolibrary.org/obo/UBERON_0000479 |
| T16 | 1490-1499 | Body_part | denotes | stem cell | http://purl.obolibrary.org/obo/CL_0000034 |