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PubMed:27781960 JSONTXT

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Parkinson

Id Subject Object Predicate Lexical cue
T1 131-136 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T2 352-357 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T3 509-514 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T4 804-809 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T5 927-932 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T6 402-409 http://purl.obolibrary.org/obo/UBERON_0012131 denotes central
T7 410-435 http://purl.obolibrary.org/obo/UBERON_0018229 denotes rennin angiotensin system

parkinson

Id Subject Object Predicate Lexical cue
T1 0-11 http://purl.obolibrary.org/obo/CHEBI_80127 denotes Angiotensin
T2 0-11 http://purl.obolibrary.org/obo/CHEBI_2720 denotes Angiotensin
T3 0-11 http://purl.obolibrary.org/obo/CHEBI_48433 denotes Angiotensin
T4 0-11 http://purl.obolibrary.org/obo/CHEBI_2718 denotes Angiotensin
T5 0-11 http://purl.obolibrary.org/obo/CHEBI_48432 denotes Angiotensin
T6 21-30 http://purl.obolibrary.org/obo/CHEBI_25741 denotes Oxidative
T7 31-37 http://togodb.biosciencedbc.jp/ontology/dgby_main_en%23stress denotes Stress
T8 42-57 http://purl.obolibrary.org/obo/CHEBI_63726 denotes Neuroprotective
T9 71-83 http://purl.obolibrary.org/obo/CHEBI_22586 denotes Antioxidants
T10 111-120 http://purl.obolibrary.org/obo/CHEBI_25741 denotes Oxidative
T11 121-127 http://togodb.biosciencedbc.jp/ontology/dgby_main_en%23stress denotes stress
T12 157-169 http://edamontology.org/topic_3304 denotes neurological
T13 157-169 http://edamontology.org/topic_3334 denotes neurological
T14 202-209 http://togodb.biosciencedbc.jp/ontology/kegg_medicus_disease%23entry denotes disease
T15 202-209 http://togodb.biosciencedbc.jp/ontology/kegg_medicus_disease_en%23entry denotes disease
T16 202-209 http://togodb.biosciencedbc.jp/ontology/hgold_main%23disease denotes disease
T17 219-228 http://purl.obolibrary.org/obo/NCBITaxon_58885 denotes Parkinson
T18 231-238 http://togodb.biosciencedbc.jp/ontology/kegg_medicus_disease_en%23entry denotes disease
T19 231-238 http://togodb.biosciencedbc.jp/ontology/kegg_medicus_disease%23entry denotes disease
T20 231-238 http://togodb.biosciencedbc.jp/ontology/hgold_main%23disease denotes disease
T21 259-270 http://purl.obolibrary.org/obo/CHEBI_2720 denotes Angiotensin
T22 259-270 http://purl.obolibrary.org/obo/CHEBI_48433 denotes Angiotensin
T23 259-273 http://purl.obolibrary.org/obo/CHEBI_80127 denotes Angiotensin-II
T24 259-273 http://purl.obolibrary.org/obo/CHEBI_48432 denotes Angiotensin-II
T25 259-273 http://purl.obolibrary.org/obo/CHEBI_2718 denotes Angiotensin-II
T26 285-293 http://purl.obolibrary.org/obo/CHEBI_35224 denotes effector
T27 345-351 http://togodb.biosciencedbc.jp/ontology/massbase_sample_main%23accession denotes access
T28 345-351 http://togodb.biosciencedbc.jp/ontology/rmg_nuclear_like_seq%23accession denotes access
T29 345-351 http://togodb.biosciencedbc.jp/ontology/knapsack_motorcycle_gene%23accession denotes access
T30 345-351 http://togodb.biosciencedbc.jp/ontology/massbank_main%23accession denotes access
T31 382-386 http://togodb.biosciencedbc.jp/ontology/riken_ssbc_crystallization_kit%23well denotes well
T32 382-386 http://togodb.biosciencedbc.jp/ontology/riken_ssbc_crystal%23well denotes well
T33 390-398 http://togodb.biosciencedbc.jp/ontology/jsnp_list%23location denotes location
T34 390-398 http://togodb.biosciencedbc.jp/ontology/eddass_soil%23google_map_link denotes location
T35 390-398 http://togodb.biosciencedbc.jp/ontology/germline_sb_transposon%23location denotes location
T36 390-398 http://togodb.biosciencedbc.jp/ontology/eddass_dgge%23google_map_link denotes location
T37 390-398 http://togodb.biosciencedbc.jp/ontology/sahg_protein%23location denotes location
T38 417-428 http://purl.obolibrary.org/obo/CHEBI_48433 denotes angiotensin
T39 417-428 http://purl.obolibrary.org/obo/CHEBI_2720 denotes angiotensin
T40 417-428 http://purl.obolibrary.org/obo/CHEBI_48432 denotes angiotensin
T41 417-428 http://purl.obolibrary.org/obo/CHEBI_2718 denotes angiotensin
T42 417-428 http://purl.obolibrary.org/obo/CHEBI_80127 denotes angiotensin
T43 477-485 http://purl.obolibrary.org/obo/CHEBI_35224 denotes effector
T44 489-498 http://purl.obolibrary.org/obo/CHEBI_25741 denotes oxidative
T45 499-505 http://togodb.biosciencedbc.jp/ontology/dgby_main_en%23stress denotes stress
T46 533-545 http://purl.obolibrary.org/obo/CHEBI_22586 denotes antioxidants
T47 565-574 http://purl.obolibrary.org/obo/CHEBI_25741 denotes oxidative
T48 575-581 http://togodb.biosciencedbc.jp/ontology/dgby_main_en%23stress denotes stress
T49 753-758 http://purl.obolibrary.org/obo/CHEBI_23888 denotes drugs
T50 753-758 http://togodb.biosciencedbc.jp/ontology/kegg_medicus_drug_en%23entry denotes drugs
T51 753-758 http://togodb.biosciencedbc.jp/ontology/kegg_medicus_disease_en%23drug_in_html denotes drugs
T52 753-758 http://togodb.biosciencedbc.jp/ontology/kegg_medicus_drug%23entry denotes drugs
T53 753-758 http://togodb.biosciencedbc.jp/ontology/kegg_medicus_disease_en%23drug denotes drugs
T54 769-780 http://purl.obolibrary.org/obo/CHEBI_9434 denotes telmisartan
T55 826-832 http://togodb.biosciencedbc.jp/ontology/kaiko_cdna_cluster%23other denotes others
T56 826-832 http://togodb.biosciencedbc.jp/ontology/riken_ssbc_crystallization_kit%23other denotes others
T57 842-848 http://togodb.biosciencedbc.jp/ontology/tp_atlas%23review_with_link denotes review
T58 842-848 http://togodb.biosciencedbc.jp/ontology/tp_atlas_en%23review_with_link denotes review
T59 842-848 http://togodb.biosciencedbc.jp/ontology/tp_atlas_en%23review denotes review
T60 842-848 http://togodb.biosciencedbc.jp/ontology/tp_atlas%23review denotes review
T61 884-896 http://purl.obolibrary.org/obo/CHEBI_22586 denotes antioxidants
T62 907-916 http://purl.obolibrary.org/obo/CHEBI_25741 denotes oxidative
T63 917-923 http://togodb.biosciencedbc.jp/ontology/dgby_main_en%23stress denotes stress
T64 957-965 http://togodb.biosciencedbc.jp/ontology/kaiko_cdna_interpro%23analysis denotes analysis
T65 957-965 http://edamontology.org/operation_2945 denotes analysis
T66 991-1000 http://togodb.biosciencedbc.jp/ontology/knapsack_worldcore%23purpose denotes purposing
T67 1025-1034 http://purl.obolibrary.org/obo/CHEBI_25741 denotes oxidative
T68 1035-1041 http://togodb.biosciencedbc.jp/ontology/dgby_main_en%23stress denotes stress

Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-110 Sentence denotes Angiotensin Mediated Oxidative Stress and Neuroprotective Potential of Antioxidants and AT1 Receptor Blockers.
T2 111-244 Sentence denotes Oxidative stress in brain underlies the major neurological disorders including Alzheimer's disease (AD) and Parkinson's disease (PD).
T3 245-310 Sentence denotes Peripherally, Angiotensin-II is a major effector of inflammation.
T4 311-515 Sentence denotes Identification of its capacity to access brain during hypertension, as well as location of central rennin angiotensin system have led to its recognition as the major effector of oxidative stress in brain.
T5 516-601 Sentence denotes Clinical uses of antioxidants to antagonize this oxidative stress have mostly failed.
T6 602-685 Sentence denotes In this scenario, AT1 blockers have been investigated to prevent neurodegeneration.
T7 686-833 Sentence denotes Although it has shown promise, clinical efficacy is limited to few drugs including telmisartan mainly due to the poor brain availability of others.
T8 834-933 Sentence denotes In this review we aim to analyse the potential of antioxidants to reduce oxidative stress in brain.
T9 934-1068 Sentence denotes We have given critical analysis of the approaches for re-purposing of AT1 blockers against oxidative stress induced neurodegeneration.
T1 0-110 Sentence denotes Angiotensin Mediated Oxidative Stress and Neuroprotective Potential of Antioxidants and AT1 Receptor Blockers.
T2 111-244 Sentence denotes Oxidative stress in brain underlies the major neurological disorders including Alzheimer's disease (AD) and Parkinson's disease (PD).
T3 245-310 Sentence denotes Peripherally, Angiotensin-II is a major effector of inflammation.
T4 311-515 Sentence denotes Identification of its capacity to access brain during hypertension, as well as location of central rennin angiotensin system have led to its recognition as the major effector of oxidative stress in brain.
T5 516-601 Sentence denotes Clinical uses of antioxidants to antagonize this oxidative stress have mostly failed.
T6 602-685 Sentence denotes In this scenario, AT1 blockers have been investigated to prevent neurodegeneration.
T7 686-833 Sentence denotes Although it has shown promise, clinical efficacy is limited to few drugs including telmisartan mainly due to the poor brain availability of others.
T8 834-933 Sentence denotes In this review we aim to analyse the potential of antioxidants to reduce oxidative stress in brain.
T9 934-1068 Sentence denotes We have given critical analysis of the approaches for re-purposing of AT1 blockers against oxidative stress induced neurodegeneration.