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PubMed:27775984 JSONTXT

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PubMed_ArguminSci

Id Subject Object Predicate Lexical cue
T1 100-254 DRI_Background denotes Mafenide acetate is used in some burn wounds for its ability to penetrate eschar but requires frequent uncomfortable dressing changes for its application.
T2 255-502 DRI_Background denotes The authors hypothesize that hydrofiber dressings will hold mafenide acetate solution for an extended period of time and maintain antimicrobial activity longer than traditional gauze, thus possibly obviating the need for frequent dressing changes.
T3 503-830 DRI_Background denotes Four experimental arms included: 1) hydrofiber, stored on a dry well plate as control, 2) gauze saturated with 2.5% mafenide acetate, stored on nonsterile porcine skin, 3) hydrofiber saturated with mafenide acetate, stored on dry well plate, and 4) hydrofiber saturated with mafenide acetate, stored on nonsterile porcine skin.
T4 831-1074 DRI_Outcome denotes At 0, 24, 48, and 72 hours, a 1-cm disk was cut from the dressing sheet of each study arm, placed on agar plates seeded with Staphylococcus aureus and Pseudomonas aeruginosa, and incubated for 24 hours, and the zone of inhibition was measured.
T5 1075-1134 DRI_Background denotes A zone of 2 mm or greater was indicative of susceptibility.
T6 1135-1218 DRI_Approach denotes Each arm of the experiment was performed four times to demonstrate reproducibility.
T7 1219-1351 DRI_Approach denotes Plain hydrofiber (control) demonstrated no zone of inhibition at any time point, thereby possessing no antimicrobial activity alone.
T8 1352-1457 DRI_Outcome denotes Gauze saturated with mafenide acetate did not reliably demonstrate antimicrobial activity beyond 0 hours.
T9 1458-1714 DRI_Outcome denotes Hydrofiber saturated with mafenide acetate, whether stored on a dry well plate or nonsterile porcine skin, consistently possessed sustained antimicrobial activity as demonstrated by zones of inhibition greater than 2 mm to both S. aureus and P. aeruginosa.
T10 1715-1738 REPLACED denotes Mafenide acetate-soaked
T11 1750-1888 DRI_Background denotes dressings stay moist and maintain antimicrobial activity against S. aureus and P. aeruginosa for at least 72 hours without repeated soaks.

Goldhamster2_Cellosaurus

Id Subject Object Predicate Lexical cue
T1 90-98 CVCL_C410|Hybridoma|Mus musculus denotes Activity
T2 226-233 CVCL_0238|Cancer_cell_line|Homo sapiens denotes changes
T3 345-347 CVCL_8754|Cancer_cell_line|Homo sapiens denotes an
T4 345-347 CVCL_H241|Cancer_cell_line|Homo sapiens denotes an
T5 367-371 CVCL_0047|Telomerase_immortalized_cell_line|Homo sapiens denotes time
T6 399-407 CVCL_C410|Hybridoma|Mus musculus denotes activity
T7 494-501 CVCL_0238|Cancer_cell_line|Homo sapiens denotes changes
T8 561-562 CVCL_6479|Finite_cell_line|Mus musculus denotes a
T9 572-577 CVCL_B488|Transformed_cell_line|Homo sapiens denotes plate
T10 738-743 CVCL_B488|Transformed_cell_line|Homo sapiens denotes plate
T11 745-750 CVCL_K225|Induced_pluripotent_stem_cell|Homo sapiens denotes and 4
T12 841-843 CVCL_J728|Hybridoma|Mus musculus denotes 48
T13 859-862 CVCL_6G43|Cancer_cell_line|Homo sapiens denotes a 1
T14 859-862 CVCL_RG52|Induced_pluripotent_stem_cell|Homo sapiens denotes a 1
T15 859-862 CVCL_VA32|Cancer_cell_line|Homo sapiens denotes a 1
T16 859-860 CVCL_6479|Finite_cell_line|Mus musculus denotes a
T17 863-865 CVCL_H246|Cancer_cell_line|Homo sapiens denotes cm
T18 937-943 CVCL_B488|Transformed_cell_line|Homo sapiens denotes plates
T19 1075-1076 CVCL_6479|Finite_cell_line|Mus musculus denotes A
T20 1181-1186 CVCL_0047|Telomerase_immortalized_cell_line|Homo sapiens denotes times
T21 1288-1292 CVCL_0047|Telomerase_immortalized_cell_line|Homo sapiens denotes time
T22 1336-1344 CVCL_C410|Hybridoma|Mus musculus denotes activity
T23 1433-1441 CVCL_C410|Hybridoma|Mus musculus denotes activity
T24 1520-1521 CVCL_6479|Finite_cell_line|Mus musculus denotes a
T25 1531-1536 CVCL_B488|Transformed_cell_line|Homo sapiens denotes plate
T26 1612-1620 CVCL_C410|Hybridoma|Mus musculus denotes activity
T27 1798-1806 CVCL_C410|Hybridoma|Mus musculus denotes activity

GoldHamster

Id Subject Object Predicate Lexical cue
T5 35-51 6573 denotes Mafenide Acetate
T6 35-51 D008272 denotes Mafenide Acetate
T7 35-51 CHEBI:31792 denotes Mafenide Acetate
T8 35-51 CHEBI:6633 denotes Mafenide Acetate
T9 35-51 D008272 denotes Mafenide Acetate
T13 76-89 CHEBI:33281 denotes Antimicrobial
T15 109-116 164 denotes acetate
T14 109-116 CHEBI:47622 denotes acetate
T16 109-116 CHEBI:30089 denotes acetate
T21 315-331 6573 denotes mafenide acetate
T22 315-331 D008272 denotes mafenide acetate
T23 315-331 CHEBI:31792 denotes mafenide acetate
T24 315-331 CHEBI:6633 denotes mafenide acetate
T25 315-331 D008272 denotes mafenide acetate
T29 332-340 CHEBI:75958 denotes solution
T30 385-398 CHEBI:33281 denotes antimicrobial
T31 521-525 PR:Q7T163 denotes arms
T32 563-566 PR:Q24498 denotes dry
T33 572-577 UBERON:6004475 denotes plate
T34 572-577 UBERON:0003148 denotes plate
T39 619-635 6573 denotes mafenide acetate
T40 619-635 D008272 denotes mafenide acetate
T41 619-635 CHEBI:31792 denotes mafenide acetate
T42 619-635 CHEBI:6633 denotes mafenide acetate
T43 619-635 D008272 denotes mafenide acetate
T47 666-670 UBERON:0002199 denotes skin
T48 666-670 UBERON:0000014 denotes skin
T49 666-670 UBERON:0001003 denotes skin
T50 666-670 UBERON:0002097 denotes skin
T55 701-717 6573 denotes mafenide acetate
T56 701-717 D008272 denotes mafenide acetate
T57 701-717 CHEBI:31792 denotes mafenide acetate
T58 701-717 CHEBI:6633 denotes mafenide acetate
T59 701-717 D008272 denotes mafenide acetate
T63 729-732 PR:Q24498 denotes dry
T64 738-743 UBERON:6004475 denotes plate
T65 738-743 UBERON:0003148 denotes plate
T71 778-794 6573 denotes mafenide acetate
T72 778-794 D008272 denotes mafenide acetate
T73 778-794 CHEBI:31792 denotes mafenide acetate
T74 778-794 CHEBI:6633 denotes mafenide acetate
T75 778-794 D008272 denotes mafenide acetate
T79 825-829 UBERON:0002199 denotes skin
T80 825-829 UBERON:0000014 denotes skin
T81 825-829 UBERON:0001003 denotes skin
T82 825-829 UBERON:0002097 denotes skin
T83 917-920 PR:P18824 denotes arm
T84 917-920 PR:Q9XZT1 denotes arm
T85 917-920 UBERON:0003822 denotes arm
T86 917-920 UBERON:0001460 denotes arm
T89 932-936 PR:000032943 denotes agar
T92 932-936 PR:P0ACK2 denotes agar
T90 932-936 397 denotes agar
T87 932-936 D000362 denotes agar
T88 932-936 D000362 denotes agar
T91 932-936 CHEBI:2509 denotes agar
T94 956-977 D013211 denotes Staphylococcus aureus
T95 956-977 1280 denotes Staphylococcus aureus
T97 982-1004 287 denotes Pseudomonas aeruginosa
T98 982-1004 D011550 denotes Pseudomonas aeruginosa
T100 1119-1133 D004198 denotes susceptibility
T101 1119-1133 D004198 denotes susceptibility
T102 1140-1143 PR:P18824 denotes arm
T103 1140-1143 PR:Q9XZT1 denotes arm
T104 1140-1143 UBERON:0003822 denotes arm
T105 1140-1143 UBERON:0001460 denotes arm
T106 1322-1335 CHEBI:33281 denotes antimicrobial
T111 1373-1389 6573 denotes mafenide acetate
T112 1373-1389 D008272 denotes mafenide acetate
T113 1373-1389 CHEBI:31792 denotes mafenide acetate
T114 1373-1389 CHEBI:6633 denotes mafenide acetate
T115 1373-1389 D008272 denotes mafenide acetate
T119 1419-1432 CHEBI:33281 denotes antimicrobial
T124 1484-1500 6573 denotes mafenide acetate
T125 1484-1500 D008272 denotes mafenide acetate
T126 1484-1500 CHEBI:31792 denotes mafenide acetate
T127 1484-1500 CHEBI:6633 denotes mafenide acetate
T128 1484-1500 D008272 denotes mafenide acetate
T132 1522-1525 PR:Q24498 denotes dry
T133 1531-1536 UBERON:6004475 denotes plate
T134 1531-1536 UBERON:0003148 denotes plate
T135 1559-1563 UBERON:0002199 denotes skin
T136 1559-1563 UBERON:0000014 denotes skin
T137 1559-1563 UBERON:0001003 denotes skin
T138 1559-1563 UBERON:0002097 denotes skin
T139 1598-1611 CHEBI:33281 denotes antimicrobial
T144 1715-1731 6573 denotes Mafenide acetate
T145 1715-1731 D008272 denotes Mafenide acetate
T146 1715-1731 CHEBI:31792 denotes Mafenide acetate
T147 1715-1731 CHEBI:6633 denotes Mafenide acetate
T148 1715-1731 D008272 denotes Mafenide acetate
T152 1784-1797 CHEBI:33281 denotes antimicrobial