PubMed:26847345 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/26847345","sourcedb":"PubMed","sourceid":"26847345","text":"Transgelin increases metastatic potential of colorectal cancer cells in vivo and alters expression of genes involved in cell motility.\nBACKGROUND: Transgelin is an actin-binding protein that promotes motility in normal cells. Although the role of transgelin in cancer is controversial, a number of studies have shown that elevated levels correlate with aggressive tumor behavior, advanced stage, and poor prognosis. Here we sought to determine the role of transgelin more directly by determining whether experimental manipulation of transgelin levels in colorectal cancer (CRC) cells led to changes in metastatic potential in vivo.\nMETHODS: Isogenic CRC cell lines that differ in transgelin expression were characterized using in vitro assays of growth and invasiveness and a mouse tail vein assay of experimental metastasis. Downstream effects of transgelin overexpression were investigated by gene expression profiling and quantitative PCR.\nRESULTS: Stable overexpression of transgelin in RKO cells, which have low endogenous levels, led to increased invasiveness, growth at low density, and growth in soft agar. Overexpression also led to an increase in the number and size of lung metastases in the mouse tail vein injection model. Similarly, attenuation of transgelin expression in HCT116 cells, which have high endogenous levels, decreased metastases in the same model. Investigation of mRNA expression patterns showed that transgelin overexpression altered the levels of approximately 250 other transcripts, with over-representation of genes that affect function of actin or other cytoskeletal proteins. Changes included increases in HOOK1, SDCCAG8, ENAH/Mena, and TNS1 and decreases in EMB, BCL11B, and PTPRD.\nCONCLUSIONS: Increases or decreases in transgelin levels have reciprocal effects on tumor cell behavior, with higher expression promoting metastasis. Chronic overexpression influences steady-state levels of mRNAs for metastasis-related genes.","tracks":[{"project":"LitCoin-entities","denotations":[{"id":"11027","span":{"begin":0,"end":10},"obj":"GeneOrGeneProduct"},{"id":"11028","span":{"begin":45,"end":62},"obj":"DiseaseOrPhenotypicFeature"},{"id":"11029","span":{"begin":147,"end":157},"obj":"GeneOrGeneProduct"},{"id":"11030","span":{"begin":164,"end":185},"obj":"GeneOrGeneProduct"},{"id":"11031","span":{"begin":247,"end":257},"obj":"GeneOrGeneProduct"},{"id":"11032","span":{"begin":261,"end":267},"obj":"DiseaseOrPhenotypicFeature"},{"id":"11033","span":{"begin":364,"end":369},"obj":"DiseaseOrPhenotypicFeature"},{"id":"11034","span":{"begin":456,"end":466},"obj":"GeneOrGeneProduct"},{"id":"11035","span":{"begin":533,"end":543},"obj":"GeneOrGeneProduct"},{"id":"11036","span":{"begin":554,"end":571},"obj":"DiseaseOrPhenotypicFeature"},{"id":"11037","span":{"begin":573,"end":576},"obj":"DiseaseOrPhenotypicFeature"},{"id":"11038","span":{"begin":650,"end":653},"obj":"DiseaseOrPhenotypicFeature"},{"id":"11039","span":{"begin":680,"end":690},"obj":"GeneOrGeneProduct"},{"id":"11040","span":{"begin":776,"end":781},"obj":"OrganismTaxon"},{"id":"11041","span":{"begin":848,"end":858},"obj":"GeneOrGeneProduct"},{"id":"11042","span":{"begin":977,"end":987},"obj":"GeneOrGeneProduct"},{"id":"11043","span":{"begin":991,"end":994},"obj":"CellLine"},{"id":"11044","span":{"begin":1180,"end":1195},"obj":"DiseaseOrPhenotypicFeature"},{"id":"11045","span":{"begin":1203,"end":1208},"obj":"OrganismTaxon"},{"id":"11046","span":{"begin":1262,"end":1272},"obj":"GeneOrGeneProduct"},{"id":"11047","span":{"begin":1287,"end":1293},"obj":"CellLine"},{"id":"11048","span":{"begin":1346,"end":1356},"obj":"DiseaseOrPhenotypicFeature"},{"id":"11049","span":{"begin":1430,"end":1440},"obj":"GeneOrGeneProduct"},{"id":"11050","span":{"begin":1573,"end":1578},"obj":"GeneOrGeneProduct"},{"id":"11051","span":{"begin":1588,"end":1609},"obj":"GeneOrGeneProduct"},{"id":"11052","span":{"begin":1641,"end":1646},"obj":"GeneOrGeneProduct"},{"id":"11053","span":{"begin":1648,"end":1655},"obj":"GeneOrGeneProduct"},{"id":"11054","span":{"begin":1657,"end":1661},"obj":"GeneOrGeneProduct"},{"id":"11055","span":{"begin":1662,"end":1666},"obj":"GeneOrGeneProduct"},{"id":"11056","span":{"begin":1672,"end":1676},"obj":"GeneOrGeneProduct"},{"id":"11057","span":{"begin":1694,"end":1697},"obj":"GeneOrGeneProduct"},{"id":"11058","span":{"begin":1699,"end":1705},"obj":"GeneOrGeneProduct"},{"id":"11059","span":{"begin":1711,"end":1716},"obj":"GeneOrGeneProduct"},{"id":"11060","span":{"begin":1757,"end":1767},"obj":"GeneOrGeneProduct"},{"id":"11061","span":{"begin":1802,"end":1807},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A20","pred":"db_id","subj":"11045","obj":"NCBITaxon:10090"},{"id":"A10","pred":"db_id","subj":"11035","obj":"NCBIGene:6876"},{"id":"A12","pred":"db_id","subj":"11037","obj":"MESH:D015179"},{"id":"A39","pred":"db_id","subj":"11061","obj":"MESH:D009369"},{"id":"A6","pred":"db_id","subj":"11031","obj":"NCBIGene:6876"},{"id":"A13","pred":"db_id","subj":"11038","obj":"MESH:D015179"},{"id":"A38","pred":"db_id","subj":"11060","obj":"NCBIGene:6876"},{"id":"A2","pred":"db_id","subj":"11028","obj":"MESH:D015179"},{"id":"A30","pred":"db_id","subj":"11052","obj":"NCBIGene:51361"},{"id":"A15","pred":"db_id","subj":"11040","obj":"NCBITaxon:10090"},{"id":"A17","pred":"db_id","subj":"11042","obj":"NCBIGene:6876"},{"id":"A24","pred":"db_id","subj":"11049","obj":"NCBIGene:6876"},{"id":"A23","pred":"db_id","subj":"11048","obj":"MESH:D009362"},{"id":"A34","pred":"db_id","subj":"11056","obj":"NCBIGene:7145"},{"id":"A35","pred":"db_id","subj":"11057","obj":"NCBIGene:133418"},{"id":"A1","pred":"db_id","subj":"11027","obj":"NCBIGene:6876"},{"id":"A4","pred":"db_id","subj":"11030","obj":"NCBIGene:21345"},{"id":"A5","pred":"db_id","subj":"11030","obj":"NCBIGene:6876"},{"id":"A19","pred":"db_id","subj":"11044","obj":"MESH:D008175"},{"id":"A25","pred":"db_id","subj":"11050","obj":"NCBIGene:60"},{"id":"A33","pred":"db_id","subj":"11055","obj":"NCBIGene:55740"},{"id":"A22","pred":"db_id","subj":"11047","obj":"NCBITaxon:9606"},{"id":"A32","pred":"db_id","subj":"11054","obj":"NCBIGene:55740"},{"id":"A36","pred":"db_id","subj":"11058","obj":"NCBIGene:64919"},{"id":"A8","pred":"db_id","subj":"11033","obj":"MESH:D009369"},{"id":"A14","pred":"db_id","subj":"11039","obj":"NCBIGene:6876"},{"id":"A31","pred":"db_id","subj":"11053","obj":"NCBIGene:10806"},{"id":"A26","pred":"db_id","subj":"11051","obj":"NCBIGene:51361"},{"id":"A27","pred":"db_id","subj":"11051","obj":"NCBIGene:55740"},{"id":"A28","pred":"db_id","subj":"11051","obj":"NCBIGene:6876"},{"id":"A29","pred":"db_id","subj":"11051","obj":"NCBIGene:7145"},{"id":"A21","pred":"db_id","subj":"11046","obj":"NCBIGene:6876"},{"id":"A9","pred":"db_id","subj":"11034","obj":"NCBIGene:6876"},{"id":"A11","pred":"db_id","subj":"11036","obj":"MESH:D015179"},{"id":"A7","pred":"db_id","subj":"11032","obj":"MESH:D009369"},{"id":"A16","pred":"db_id","subj":"11041","obj":"NCBIGene:6876"},{"id":"A3","pred":"db_id","subj":"11029","obj":"NCBIGene:6876"},{"id":"A18","pred":"db_id","subj":"11043","obj":"NCBITaxon:9606"},{"id":"A37","pred":"db_id","subj":"11059","obj":"NCBIGene:5789"},{"subj":"11027","pred":"source","obj":"LitCoin-entities"},{"subj":"11028","pred":"source","obj":"LitCoin-entities"},{"subj":"11029","pred":"source","obj":"LitCoin-entities"},{"subj":"11030","pred":"source","obj":"LitCoin-entities"},{"subj":"11031","pred":"source","obj":"LitCoin-entities"},{"subj":"11032","pred":"source","obj":"LitCoin-entities"},{"subj":"11033","pred":"source","obj":"LitCoin-entities"},{"subj":"11034","pred":"source","obj":"LitCoin-entities"},{"subj":"11035","pred":"source","obj":"LitCoin-entities"},{"subj":"11036","pred":"source","obj":"LitCoin-entities"},{"subj":"11037","pred":"source","obj":"LitCoin-entities"},{"subj":"11038","pred":"source","obj":"LitCoin-entities"},{"subj":"11039","pred":"source","obj":"LitCoin-entities"},{"subj":"11040","pred":"source","obj":"LitCoin-entities"},{"subj":"11041","pred":"source","obj":"LitCoin-entities"},{"subj":"11042","pred":"source","obj":"LitCoin-entities"},{"subj":"11043","pred":"source","obj":"LitCoin-entities"},{"subj":"11044","pred":"source","obj":"LitCoin-entities"},{"subj":"11045","pred":"source","obj":"LitCoin-entities"},{"subj":"11046","pred":"source","obj":"LitCoin-entities"},{"subj":"11047","pred":"source","obj":"LitCoin-entities"},{"subj":"11048","pred":"source","obj":"LitCoin-entities"},{"subj":"11049","pred":"source","obj":"LitCoin-entities"},{"subj":"11050","pred":"source","obj":"LitCoin-entities"},{"subj":"11051","pred":"source","obj":"LitCoin-entities"},{"subj":"11052","pred":"source","obj":"LitCoin-entities"},{"subj":"11053","pred":"source","obj":"LitCoin-entities"},{"subj":"11054","pred":"source","obj":"LitCoin-entities"},{"subj":"11055","pred":"source","obj":"LitCoin-entities"},{"subj":"11056","pred":"source","obj":"LitCoin-entities"},{"subj":"11057","pred":"source","obj":"LitCoin-entities"},{"subj":"11058","pred":"source","obj":"LitCoin-entities"},{"subj":"11059","pred":"source","obj":"LitCoin-entities"},{"subj":"11060","pred":"source","obj":"LitCoin-entities"},{"subj":"11061","pred":"source","obj":"LitCoin-entities"}],"namespaces":[{"prefix":"_base","uri":"https://w3id.org/biolink/vocab/"},{"prefix":"MESH","uri":"http://id.nlm.nih.gov/mesh/"},{"prefix":"NCBITaxon","uri":"https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id="},{"prefix":"NCBIGene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"OMIM","uri":"https://www.omim.org/entry/"},{"prefix":"DBSNP","uri":"https://www.ncbi.nlm.nih.gov/snp/"}]},{"project":"LitCoin-sentences","denotations":[{"id":"T1","span":{"begin":0,"end":134},"obj":"Sentence"},{"id":"T2","span":{"begin":135,"end":146},"obj":"Sentence"},{"id":"T3","span":{"begin":147,"end":225},"obj":"Sentence"},{"id":"T4","span":{"begin":226,"end":415},"obj":"Sentence"},{"id":"T5","span":{"begin":416,"end":631},"obj":"Sentence"},{"id":"T6","span":{"begin":632,"end":640},"obj":"Sentence"},{"id":"T7","span":{"begin":641,"end":825},"obj":"Sentence"},{"id":"T8","span":{"begin":826,"end":942},"obj":"Sentence"},{"id":"T9","span":{"begin":943,"end":951},"obj":"Sentence"},{"id":"T10","span":{"begin":952,"end":1114},"obj":"Sentence"},{"id":"T11","span":{"begin":1115,"end":1235},"obj":"Sentence"},{"id":"T12","span":{"begin":1236,"end":1375},"obj":"Sentence"},{"id":"T13","span":{"begin":1376,"end":1610},"obj":"Sentence"},{"id":"T14","span":{"begin":1611,"end":1717},"obj":"Sentence"},{"id":"T15","span":{"begin":1718,"end":1730},"obj":"Sentence"},{"id":"T16","span":{"begin":1731,"end":1867},"obj":"Sentence"},{"id":"T17","span":{"begin":1868,"end":1960},"obj":"Sentence"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCoin-sentences"},{"subj":"T2","pred":"source","obj":"LitCoin-sentences"},{"subj":"T3","pred":"source","obj":"LitCoin-sentences"},{"subj":"T4","pred":"source","obj":"LitCoin-sentences"},{"subj":"T5","pred":"source","obj":"LitCoin-sentences"},{"subj":"T6","pred":"source","obj":"LitCoin-sentences"},{"subj":"T7","pred":"source","obj":"LitCoin-sentences"},{"subj":"T8","pred":"source","obj":"LitCoin-sentences"},{"subj":"T9","pred":"source","obj":"LitCoin-sentences"},{"subj":"T10","pred":"source","obj":"LitCoin-sentences"},{"subj":"T11","pred":"source","obj":"LitCoin-sentences"},{"subj":"T12","pred":"source","obj":"LitCoin-sentences"},{"subj":"T13","pred":"source","obj":"LitCoin-sentences"},{"subj":"T14","pred":"source","obj":"LitCoin-sentences"},{"subj":"T15","pred":"source","obj":"LitCoin-sentences"},{"subj":"T16","pred":"source","obj":"LitCoin-sentences"},{"subj":"T17","pred":"source","obj":"LitCoin-sentences"}]},{"project":"LitCoin-entities-OrganismTaxon-PD","denotations":[{"id":"T1","span":{"begin":776,"end":781},"obj":"OrganismTaxon"},{"id":"T3","span":{"begin":1203,"end":1208},"obj":"OrganismTaxon"}],"attributes":[{"id":"A1","pred":"db_id","subj":"T1","obj":"NCBItxid:10090"},{"id":"A2","pred":"db_id","subj":"T1","obj":"NCBItxid:10088"},{"id":"A3","pred":"db_id","subj":"T3","obj":"NCBItxid:10090"},{"id":"A4","pred":"db_id","subj":"T3","obj":"NCBItxid:10088"},{"subj":"T1","pred":"source","obj":"LitCoin-entities-OrganismTaxon-PD"},{"subj":"T3","pred":"source","obj":"LitCoin-entities-OrganismTaxon-PD"}]},{"project":"LitCoin_Mondo","denotations":[{"id":"T1","span":{"begin":45,"end":62},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":56,"end":62},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":261,"end":267},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":554,"end":571},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T5","span":{"begin":565,"end":571},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A1","pred":"mondo_id","subj":"T1","obj":"0005575"},{"id":"A2","pred":"mondo_id","subj":"T2","obj":"0004992"},{"id":"A3","pred":"mondo_id","subj":"T3","obj":"0004992"},{"id":"A4","pred":"mondo_id","subj":"T4","obj":"0005575"},{"id":"A5","pred":"mondo_id","subj":"T5","obj":"0004992"},{"subj":"T1","pred":"source","obj":"LitCoin_Mondo"},{"subj":"T2","pred":"source","obj":"LitCoin_Mondo"},{"subj":"T3","pred":"source","obj":"LitCoin_Mondo"},{"subj":"T4","pred":"source","obj":"LitCoin_Mondo"},{"subj":"T5","pred":"source","obj":"LitCoin_Mondo"}]},{"project":"LitCoin-GeneOrGeneProduct-v0","denotations":[{"id":"T1","span":{"begin":0,"end":10},"obj":"GeneOrGeneProduct"},{"id":"T2","span":{"begin":63,"end":68},"obj":"GeneOrGeneProduct"},{"id":"T3","span":{"begin":120,"end":124},"obj":"GeneOrGeneProduct"},{"id":"T4","span":{"begin":147,"end":157},"obj":"GeneOrGeneProduct"},{"id":"T5","span":{"begin":164,"end":185},"obj":"GeneOrGeneProduct"},{"id":"T6","span":{"begin":219,"end":224},"obj":"GeneOrGeneProduct"},{"id":"T7","span":{"begin":247,"end":257},"obj":"GeneOrGeneProduct"},{"id":"T8","span":{"begin":364,"end":369},"obj":"GeneOrGeneProduct"},{"id":"T9","span":{"begin":370,"end":378},"obj":"GeneOrGeneProduct"},{"id":"T10","span":{"begin":434,"end":443},"obj":"GeneOrGeneProduct"},{"id":"T11","span":{"begin":456,"end":466},"obj":"GeneOrGeneProduct"},{"id":"T12","span":{"begin":484,"end":495},"obj":"GeneOrGeneProduct"},{"id":"T13","span":{"begin":533,"end":543},"obj":"GeneOrGeneProduct"},{"id":"T14","span":{"begin":573,"end":576},"obj":"GeneOrGeneProduct"},{"id":"T15","span":{"begin":578,"end":583},"obj":"GeneOrGeneProduct"},{"id":"T16","span":{"begin":632,"end":639},"obj":"GeneOrGeneProduct"},{"id":"T17","span":{"begin":650,"end":653},"obj":"GeneOrGeneProduct"},{"id":"T18","span":{"begin":654,"end":658},"obj":"GeneOrGeneProduct"},{"id":"T19","span":{"begin":659,"end":664},"obj":"GeneOrGeneProduct"},{"id":"T20","span":{"begin":680,"end":690},"obj":"GeneOrGeneProduct"},{"id":"T21","span":{"begin":746,"end":752},"obj":"GeneOrGeneProduct"},{"id":"T22","span":{"begin":782,"end":786},"obj":"GeneOrGeneProduct"},{"id":"T23","span":{"begin":787,"end":791},"obj":"GeneOrGeneProduct"},{"id":"T24","span":{"begin":848,"end":858},"obj":"GeneOrGeneProduct"},{"id":"T25","span":{"begin":977,"end":987},"obj":"GeneOrGeneProduct"},{"id":"T26","span":{"begin":995,"end":1000},"obj":"GeneOrGeneProduct"},{"id":"T27","span":{"begin":1067,"end":1073},"obj":"GeneOrGeneProduct"},{"id":"T28","span":{"begin":1094,"end":1100},"obj":"GeneOrGeneProduct"},{"id":"T29","span":{"begin":1104,"end":1108},"obj":"GeneOrGeneProduct"},{"id":"T30","span":{"begin":1109,"end":1113},"obj":"GeneOrGeneProduct"},{"id":"T31","span":{"begin":1172,"end":1176},"obj":"GeneOrGeneProduct"},{"id":"T32","span":{"begin":1180,"end":1184},"obj":"GeneOrGeneProduct"},{"id":"T33","span":{"begin":1209,"end":1213},"obj":"GeneOrGeneProduct"},{"id":"T34","span":{"begin":1214,"end":1218},"obj":"GeneOrGeneProduct"},{"id":"T35","span":{"begin":1236,"end":1245},"obj":"GeneOrGeneProduct"},{"id":"T36","span":{"begin":1247,"end":1258},"obj":"GeneOrGeneProduct"},{"id":"T37","span":{"begin":1262,"end":1272},"obj":"GeneOrGeneProduct"},{"id":"T38","span":{"begin":1294,"end":1299},"obj":"GeneOrGeneProduct"},{"id":"T39","span":{"begin":1312,"end":1316},"obj":"GeneOrGeneProduct"},{"id":"T40","span":{"begin":1393,"end":1397},"obj":"GeneOrGeneProduct"},{"id":"T41","span":{"begin":1430,"end":1440},"obj":"GeneOrGeneProduct"},{"id":"T42","span":{"begin":1478,"end":1491},"obj":"GeneOrGeneProduct"},{"id":"T43","span":{"begin":1496,"end":1501},"obj":"GeneOrGeneProduct"},{"id":"T44","span":{"begin":1502,"end":1513},"obj":"GeneOrGeneProduct"},{"id":"T45","span":{"begin":1573,"end":1578},"obj":"GeneOrGeneProduct"},{"id":"T46","span":{"begin":1582,"end":1587},"obj":"GeneOrGeneProduct"},{"id":"T47","span":{"begin":1588,"end":1609},"obj":"GeneOrGeneProduct"},{"id":"T48","span":{"begin":1641,"end":1646},"obj":"GeneOrGeneProduct"},{"id":"T49","span":{"begin":1648,"end":1655},"obj":"GeneOrGeneProduct"},{"id":"T50","span":{"begin":1657,"end":1661},"obj":"GeneOrGeneProduct"},{"id":"T51","span":{"begin":1662,"end":1666},"obj":"GeneOrGeneProduct"},{"id":"T52","span":{"begin":1672,"end":1676},"obj":"GeneOrGeneProduct"},{"id":"T53","span":{"begin":1694,"end":1697},"obj":"GeneOrGeneProduct"},{"id":"T54","span":{"begin":1699,"end":1705},"obj":"GeneOrGeneProduct"},{"id":"T55","span":{"begin":1711,"end":1716},"obj":"GeneOrGeneProduct"},{"id":"T56","span":{"begin":1757,"end":1767},"obj":"GeneOrGeneProduct"},{"id":"T57","span":{"begin":1802,"end":1807},"obj":"GeneOrGeneProduct"},{"id":"T58","span":{"begin":1808,"end":1812},"obj":"GeneOrGeneProduct"},{"id":"T59","span":{"begin":1813,"end":1821},"obj":"GeneOrGeneProduct"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T2","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T3","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T4","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T5","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T6","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T7","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T8","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T9","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T10","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T11","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T12","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T13","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T14","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T15","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T16","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T17","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T18","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T19","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T20","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T21","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T22","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T23","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T24","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T25","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T26","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T27","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T28","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T29","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T30","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T31","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T32","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T33","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T34","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T35","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T36","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T37","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T38","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T39","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T40","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T41","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T42","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T43","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T44","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T45","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T46","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T47","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T48","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T49","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T50","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T51","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T52","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T53","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T54","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T55","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T56","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T57","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T58","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T59","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"}]},{"project":"LitCoin-GeneOrGeneProduct-v2","denotations":[{"id":"T1","span":{"begin":0,"end":10},"obj":"GeneOrGeneProduct"},{"id":"T2","span":{"begin":120,"end":124},"obj":"GeneOrGeneProduct"},{"id":"T3","span":{"begin":147,"end":157},"obj":"GeneOrGeneProduct"},{"id":"T4","span":{"begin":164,"end":185},"obj":"GeneOrGeneProduct"},{"id":"T5","span":{"begin":247,"end":257},"obj":"GeneOrGeneProduct"},{"id":"T6","span":{"begin":370,"end":378},"obj":"GeneOrGeneProduct"},{"id":"T7","span":{"begin":456,"end":466},"obj":"GeneOrGeneProduct"},{"id":"T8","span":{"begin":533,"end":543},"obj":"GeneOrGeneProduct"},{"id":"T9","span":{"begin":654,"end":658},"obj":"GeneOrGeneProduct"},{"id":"T10","span":{"begin":659,"end":664},"obj":"GeneOrGeneProduct"},{"id":"T11","span":{"begin":680,"end":690},"obj":"GeneOrGeneProduct"},{"id":"T12","span":{"begin":746,"end":752},"obj":"GeneOrGeneProduct"},{"id":"T13","span":{"begin":782,"end":786},"obj":"GeneOrGeneProduct"},{"id":"T14","span":{"begin":787,"end":791},"obj":"GeneOrGeneProduct"},{"id":"T15","span":{"begin":848,"end":858},"obj":"GeneOrGeneProduct"},{"id":"T16","span":{"begin":977,"end":987},"obj":"GeneOrGeneProduct"},{"id":"T17","span":{"begin":1067,"end":1073},"obj":"GeneOrGeneProduct"},{"id":"T18","span":{"begin":1094,"end":1100},"obj":"GeneOrGeneProduct"},{"id":"T19","span":{"begin":1104,"end":1108},"obj":"GeneOrGeneProduct"},{"id":"T20","span":{"begin":1209,"end":1213},"obj":"GeneOrGeneProduct"},{"id":"T21","span":{"begin":1214,"end":1218},"obj":"GeneOrGeneProduct"},{"id":"T22","span":{"begin":1262,"end":1272},"obj":"GeneOrGeneProduct"},{"id":"T23","span":{"begin":1312,"end":1316},"obj":"GeneOrGeneProduct"},{"id":"T24","span":{"begin":1393,"end":1397},"obj":"GeneOrGeneProduct"},{"id":"T25","span":{"begin":1430,"end":1440},"obj":"GeneOrGeneProduct"},{"id":"T26","span":{"begin":1496,"end":1501},"obj":"GeneOrGeneProduct"},{"id":"T27","span":{"begin":1573,"end":1578},"obj":"GeneOrGeneProduct"},{"id":"T28","span":{"begin":1582,"end":1587},"obj":"GeneOrGeneProduct"},{"id":"T29","span":{"begin":1588,"end":1609},"obj":"GeneOrGeneProduct"},{"id":"T30","span":{"begin":1641,"end":1646},"obj":"GeneOrGeneProduct"},{"id":"T31","span":{"begin":1648,"end":1655},"obj":"GeneOrGeneProduct"},{"id":"T32","span":{"begin":1657,"end":1661},"obj":"GeneOrGeneProduct"},{"id":"T33","span":{"begin":1662,"end":1666},"obj":"GeneOrGeneProduct"},{"id":"T34","span":{"begin":1672,"end":1676},"obj":"GeneOrGeneProduct"},{"id":"T35","span":{"begin":1699,"end":1705},"obj":"GeneOrGeneProduct"},{"id":"T36","span":{"begin":1711,"end":1716},"obj":"GeneOrGeneProduct"},{"id":"T37","span":{"begin":1757,"end":1767},"obj":"GeneOrGeneProduct"},{"id":"T38","span":{"begin":1808,"end":1812},"obj":"GeneOrGeneProduct"},{"id":"T39","span":{"begin":1813,"end":1821},"obj":"GeneOrGeneProduct"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T2","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T3","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T4","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T5","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T6","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T7","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T8","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T9","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T10","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T11","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T12","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T13","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T14","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T15","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T16","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T17","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T18","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T19","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T20","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T21","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T22","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T23","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T24","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T25","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T26","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T27","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T28","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T29","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T30","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T31","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T32","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T33","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T34","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T35","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T36","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T37","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T38","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T39","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"}]},{"project":"LitCoin-NCBITaxon-2","denotations":[{"id":"T1","span":{"begin":776,"end":781},"obj":"OrganismTaxon"},{"id":"T2","span":{"begin":1203,"end":1208},"obj":"OrganismTaxon"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCoin-NCBITaxon-2"},{"subj":"T2","pred":"source","obj":"LitCoin-NCBITaxon-2"}]},{"project":"LitCoin-Disease-MeSH","denotations":[{"id":"T1","span":{"begin":45,"end":62},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":261,"end":267},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":364,"end":369},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":554,"end":571},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T5","span":{"begin":573,"end":576},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T6","span":{"begin":650,"end":653},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T7","span":{"begin":814,"end":824},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T8","span":{"begin":1185,"end":1195},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T9","span":{"begin":1346,"end":1356},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T10","span":{"begin":1802,"end":1807},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T11","span":{"begin":1856,"end":1866},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T12","span":{"begin":1935,"end":1945},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A5","pred":"originalLabel","subj":"T5","obj":"D015179"},{"id":"A4","pred":"originalLabel","subj":"T4","obj":"D015179"},{"id":"A1","pred":"originalLabel","subj":"T1","obj":"D015179"},{"id":"A6","pred":"originalLabel","subj":"T6","obj":"D015179"},{"id":"A11","pred":"originalLabel","subj":"T11","obj":"D009362"},{"id":"A3","pred":"originalLabel","subj":"T3","obj":"D009369"},{"id":"A9","pred":"originalLabel","subj":"T9","obj":"D009362"},{"id":"A12","pred":"originalLabel","subj":"T12","obj":"D009362"},{"id":"A7","pred":"originalLabel","subj":"T7","obj":"D009362"},{"id":"A8","pred":"originalLabel","subj":"T8","obj":"D009362"},{"id":"A10","pred":"originalLabel","subj":"T10","obj":"D009369"},{"id":"A2","pred":"originalLabel","subj":"T2","obj":"D009369"},{"subj":"T1","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T2","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T3","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T4","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T5","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T6","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T7","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T8","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T9","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T10","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T11","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T12","pred":"source","obj":"LitCoin-Disease-MeSH"}]},{"project":"LitCoin-GeneOrGeneProduct-v3","denotations":[{"id":"T1","span":{"begin":0,"end":10},"obj":"GeneOrGeneProduct"},{"id":"T2","span":{"begin":147,"end":157},"obj":"GeneOrGeneProduct"},{"id":"T3","span":{"begin":164,"end":185},"obj":"GeneOrGeneProduct"},{"id":"T4","span":{"begin":247,"end":257},"obj":"GeneOrGeneProduct"},{"id":"T5","span":{"begin":456,"end":466},"obj":"GeneOrGeneProduct"},{"id":"T6","span":{"begin":533,"end":543},"obj":"GeneOrGeneProduct"},{"id":"T7","span":{"begin":680,"end":690},"obj":"GeneOrGeneProduct"},{"id":"T8","span":{"begin":848,"end":858},"obj":"GeneOrGeneProduct"},{"id":"T9","span":{"begin":977,"end":987},"obj":"GeneOrGeneProduct"},{"id":"T10","span":{"begin":1262,"end":1272},"obj":"GeneOrGeneProduct"},{"id":"T11","span":{"begin":1430,"end":1440},"obj":"GeneOrGeneProduct"},{"id":"T12","span":{"begin":1573,"end":1578},"obj":"GeneOrGeneProduct"},{"id":"T13","span":{"begin":1588,"end":1609},"obj":"GeneOrGeneProduct"},{"id":"T14","span":{"begin":1641,"end":1646},"obj":"GeneOrGeneProduct"},{"id":"T15","span":{"begin":1648,"end":1655},"obj":"GeneOrGeneProduct"},{"id":"T16","span":{"begin":1657,"end":1661},"obj":"GeneOrGeneProduct"},{"id":"T17","span":{"begin":1662,"end":1666},"obj":"GeneOrGeneProduct"},{"id":"T18","span":{"begin":1672,"end":1676},"obj":"GeneOrGeneProduct"},{"id":"T19","span":{"begin":1699,"end":1705},"obj":"GeneOrGeneProduct"},{"id":"T20","span":{"begin":1711,"end":1716},"obj":"GeneOrGeneProduct"},{"id":"T21","span":{"begin":1757,"end":1767},"obj":"GeneOrGeneProduct"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T2","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T3","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T4","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T5","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T6","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T7","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T8","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T9","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T10","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T11","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T12","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T13","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T14","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T15","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T16","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T17","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T18","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T19","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T20","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T21","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"}]},{"project":"LitCoin_Mondo_095","denotations":[{"id":"T1","span":{"begin":45,"end":62},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":364,"end":369},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":554,"end":571},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T6","span":{"begin":573,"end":576},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T8","span":{"begin":650,"end":653},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T10","span":{"begin":1104,"end":1108},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T11","span":{"begin":1180,"end":1184},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T12","span":{"begin":1802,"end":1807},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A1","pred":"mondo_id","subj":"T1","obj":"0024331"},{"id":"A2","pred":"mondo_id","subj":"T1","obj":"0005575"},{"id":"A3","pred":"mondo_id","subj":"T3","obj":"0005070"},{"id":"A4","pred":"mondo_id","subj":"T4","obj":"0024331"},{"id":"A5","pred":"mondo_id","subj":"T4","obj":"0005575"},{"id":"A6","pred":"mondo_id","subj":"T6","obj":"0024331"},{"id":"A7","pred":"mondo_id","subj":"T6","obj":"0005575"},{"id":"A8","pred":"mondo_id","subj":"T8","obj":"0024331"},{"id":"A9","pred":"mondo_id","subj":"T8","obj":"0005575"},{"id":"A10","pred":"mondo_id","subj":"T10","obj":"0013894"},{"id":"A11","pred":"mondo_id","subj":"T11","obj":"0021117"},{"id":"A12","pred":"mondo_id","subj":"T12","obj":"0005070"},{"subj":"T1","pred":"source","obj":"LitCoin_Mondo_095"},{"subj":"T3","pred":"source","obj":"LitCoin_Mondo_095"},{"subj":"T4","pred":"source","obj":"LitCoin_Mondo_095"},{"subj":"T6","pred":"source","obj":"LitCoin_Mondo_095"},{"subj":"T8","pred":"source","obj":"LitCoin_Mondo_095"},{"subj":"T10","pred":"source","obj":"LitCoin_Mondo_095"},{"subj":"T11","pred":"source","obj":"LitCoin_Mondo_095"},{"subj":"T12","pred":"source","obj":"LitCoin_Mondo_095"}]},{"project":"LitCoin-MeSH-Disease-2","denotations":[{"id":"T1","span":{"begin":45,"end":62},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":261,"end":267},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":364,"end":369},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":554,"end":571},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T5","span":{"begin":573,"end":576},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T7","span":{"begin":650,"end":653},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T9","span":{"begin":814,"end":824},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T10","span":{"begin":1185,"end":1195},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T11","span":{"begin":1346,"end":1356},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T12","span":{"begin":1802,"end":1807},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T13","span":{"begin":1856,"end":1866},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T14","span":{"begin":1935,"end":1945},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A9","pred":"ID:","subj":"T9","obj":"D009362"},{"id":"A4","pred":"ID:","subj":"T4","obj":"D015179"},{"id":"A2","pred":"ID:","subj":"T2","obj":"D009369"},{"id":"A10","pred":"ID:","subj":"T10","obj":"D009362"},{"id":"A12","pred":"ID:","subj":"T12","obj":"D009369"},{"id":"A1","pred":"ID:","subj":"T1","obj":"D015179"},{"id":"A3","pred":"ID:","subj":"T3","obj":"D009369"},{"id":"A13","pred":"ID:","subj":"T13","obj":"D009362"},{"id":"A14","pred":"ID:","subj":"T14","obj":"D009362"},{"id":"A5","pred":"ID:","subj":"T5","obj":"DISEASE"},{"id":"A6","pred":"ID:","subj":"T5","obj":"D015179"},{"id":"A7","pred":"ID:","subj":"T7","obj":"DISEASE"},{"id":"A8","pred":"ID:","subj":"T7","obj":"D015179"},{"id":"A11","pred":"ID:","subj":"T11","obj":"D009362"},{"subj":"T1","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T2","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T3","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T4","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T5","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T7","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T9","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T10","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T11","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T12","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T13","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T14","pred":"source","obj":"LitCoin-MeSH-Disease-2"}]},{"project":"LitCoin_CellLine","denotations":[{"id":"T1","span":{"begin":991,"end":994},"obj":"CellLine"},{"id":"T2","span":{"begin":1287,"end":1293},"obj":"CellLine"}],"attributes":[{"id":"A1","pred":"cellosaurus_accession_id","subj":"T1","obj":"CVCL_0504"},{"id":"A2","pred":"cellosaurus_accession_id","subj":"T2","obj":"CVCL_0291"},{"subj":"T1","pred":"source","obj":"LitCoin_CellLine"},{"subj":"T2","pred":"source","obj":"LitCoin_CellLine"}]},{"project":"LitCoin-MONDO_bioort2019","denotations":[{"id":"T1","span":{"begin":45,"end":62},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":261,"end":267},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":364,"end":369},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":554,"end":571},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T5","span":{"begin":573,"end":576},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T7","span":{"begin":650,"end":653},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T9","span":{"begin":1185,"end":1195},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T10","span":{"begin":1346,"end":1356},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T11","span":{"begin":1802,"end":1807},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A4","pred":"#label","subj":"T4","obj":"D015179"},{"id":"A9","pred":"#label","subj":"T9","obj":"D009362"},{"id":"A11","pred":"#label","subj":"T11","obj":"D009369"},{"id":"A7","pred":"#label","subj":"T7","obj":"DISEASE"},{"id":"A8","pred":"#label","subj":"T7","obj":"D015179"},{"id":"A5","pred":"#label","subj":"T5","obj":"DISEASE"},{"id":"A6","pred":"#label","subj":"T5","obj":"D015179"},{"id":"A3","pred":"#label","subj":"T3","obj":"D009369"},{"id":"A10","pred":"#label","subj":"T10","obj":"D009362"},{"id":"A2","pred":"#label","subj":"T2","obj":"D009369"},{"id":"A1","pred":"#label","subj":"T1","obj":"D015179"},{"subj":"T1","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T2","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T3","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T4","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T5","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T7","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T9","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T10","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T11","pred":"source","obj":"LitCoin-MONDO_bioort2019"}]},{"project":"LitCoin-Chemical-MeSH-CHEBI","denotations":[{"id":"T1","span":{"begin":1109,"end":1113},"obj":"ChemicalEntity"},{"id":"T3","span":{"begin":1694,"end":1697},"obj":"ChemicalEntity"}],"attributes":[{"id":"A1","pred":"ID:","subj":"T1","obj":"D000362"},{"id":"A2","pred":"ID:","subj":"T1","obj":"http://purl.obolibrary.org/obo/CHEBI_2509"},{"id":"A3","pred":"ID:","subj":"T3","obj":"http://purl.obolibrary.org/obo/CHEBI_4877"},{"subj":"T1","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T3","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"}]},{"project":"LitCoin-training-merged","denotations":[{"id":"T2","span":{"begin":1287,"end":1293},"obj":"CellLine"},{"id":"T1","span":{"begin":991,"end":994},"obj":"CellLine"},{"id":"T3","span":{"begin":1694,"end":1697},"obj":"ChemicalEntity"},{"id":"T83924","span":{"begin":1109,"end":1113},"obj":"ChemicalEntity"},{"id":"T21","span":{"begin":1757,"end":1767},"obj":"GeneOrGeneProduct"},{"id":"T20","span":{"begin":1711,"end":1716},"obj":"GeneOrGeneProduct"},{"id":"T19","span":{"begin":1699,"end":1705},"obj":"GeneOrGeneProduct"},{"id":"T18","span":{"begin":1672,"end":1676},"obj":"GeneOrGeneProduct"},{"id":"T17","span":{"begin":1662,"end":1666},"obj":"GeneOrGeneProduct"},{"id":"T16","span":{"begin":1657,"end":1661},"obj":"GeneOrGeneProduct"},{"id":"T15","span":{"begin":1648,"end":1655},"obj":"GeneOrGeneProduct"},{"id":"T14","span":{"begin":1641,"end":1646},"obj":"GeneOrGeneProduct"},{"id":"T13","span":{"begin":1588,"end":1609},"obj":"GeneOrGeneProduct"},{"id":"T12","span":{"begin":1573,"end":1578},"obj":"GeneOrGeneProduct"},{"id":"T11","span":{"begin":1430,"end":1440},"obj":"GeneOrGeneProduct"},{"id":"T10","span":{"begin":1262,"end":1272},"obj":"GeneOrGeneProduct"},{"id":"T9","span":{"begin":977,"end":987},"obj":"GeneOrGeneProduct"},{"id":"T8","span":{"begin":848,"end":858},"obj":"GeneOrGeneProduct"},{"id":"T7","span":{"begin":680,"end":690},"obj":"GeneOrGeneProduct"},{"id":"T6","span":{"begin":533,"end":543},"obj":"GeneOrGeneProduct"},{"id":"T5","span":{"begin":456,"end":466},"obj":"GeneOrGeneProduct"},{"id":"T4","span":{"begin":247,"end":257},"obj":"GeneOrGeneProduct"},{"id":"T85099","span":{"begin":164,"end":185},"obj":"GeneOrGeneProduct"},{"id":"T40233","span":{"begin":147,"end":157},"obj":"GeneOrGeneProduct"},{"id":"T7432","span":{"begin":0,"end":10},"obj":"GeneOrGeneProduct"},{"id":"T22124","span":{"begin":1802,"end":1807},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T35580","span":{"begin":1346,"end":1356},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T89019","span":{"begin":1185,"end":1195},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T10693","span":{"begin":650,"end":653},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T31075","span":{"begin":573,"end":576},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T99040","span":{"begin":554,"end":571},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T72603","span":{"begin":364,"end":369},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T89036","span":{"begin":261,"end":267},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T20198","span":{"begin":45,"end":62},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T52620","span":{"begin":1203,"end":1208},"obj":"OrganismTaxon"},{"id":"T22853","span":{"begin":776,"end":781},"obj":"OrganismTaxon"}],"attributes":[{"id":"A1","pred":"cellosaurus_accession_id","subj":"T1","obj":"CVCL_0504"},{"id":"A88582","pred":"ID:","subj":"T83924","obj":"D000362"},{"id":"A3","pred":"ID:","subj":"T3","obj":"http://purl.obolibrary.org/obo/CHEBI_4877"},{"id":"A8","pred":"#label","subj":"T10693","obj":"D015179"},{"id":"A7","pred":"#label","subj":"T10693","obj":"DISEASE"},{"id":"A9","pred":"#label","subj":"T89019","obj":"D009362"},{"id":"A4","pred":"#label","subj":"T99040","obj":"D015179"},{"id":"A24518","pred":"#label","subj":"T72603","obj":"D009369"},{"id":"A11","pred":"#label","subj":"T22124","obj":"D009369"},{"id":"A6","pred":"#label","subj":"T31075","obj":"D015179"},{"id":"A5","pred":"#label","subj":"T31075","obj":"DISEASE"},{"id":"A78389","pred":"#label","subj":"T20198","obj":"D015179"},{"id":"A71065","pred":"#label","subj":"T89036","obj":"D009369"},{"id":"A10","pred":"#label","subj":"T35580","obj":"D009362"},{"id":"A2","pred":"cellosaurus_accession_id","subj":"T2","obj":"CVCL_0291"},{"id":"A85135","pred":"ID:","subj":"T83924","obj":"http://purl.obolibrary.org/obo/CHEBI_2509"},{"subj":"T2","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T1","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T3","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T83924","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T21","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T20","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T19","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T18","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T17","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T16","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T15","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T14","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T13","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T12","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T11","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T10","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T9","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T8","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T7","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T6","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T5","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T4","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T85099","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T40233","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T7432","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T22124","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T35580","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T89019","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T10693","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T31075","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T99040","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T72603","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T89036","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T20198","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T52620","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T22853","pred":"source","obj":"LitCoin-training-merged"}]},{"project":"DisGeNET5_gene_disease","denotations":[{"id":"26847345-0#0#10#gene6876","span":{"begin":147,"end":157},"obj":"gene6876"},{"id":"26847345-0#45#62#diseaseC0009402","span":{"begin":554,"end":571},"obj":"diseaseC0009402"},{"id":"26847345-0#45#62#diseaseC1527249","span":{"begin":554,"end":571},"obj":"diseaseC1527249"},{"id":"26847345-11#26#36#gene6876","span":{"begin":1757,"end":1767},"obj":"gene6876"},{"id":"26847345-11#125#135#diseaseC0027627","span":{"begin":1856,"end":1866},"obj":"diseaseC0027627"}],"relations":[{"id":"0#10#gene687645#62#diseaseC0009402","pred":"associated_with","subj":"26847345-0#0#10#gene6876","obj":"26847345-0#45#62#diseaseC0009402"},{"id":"0#10#gene687645#62#diseaseC1527249","pred":"associated_with","subj":"26847345-0#0#10#gene6876","obj":"26847345-0#45#62#diseaseC1527249"},{"id":"26#36#gene6876125#135#diseaseC0027627","pred":"associated_with","subj":"26847345-11#26#36#gene6876","obj":"26847345-11#125#135#diseaseC0027627"}],"attributes":[{"subj":"26847345-0#0#10#gene6876","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"26847345-0#45#62#diseaseC0009402","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"26847345-0#45#62#diseaseC1527249","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"26847345-11#26#36#gene6876","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"26847345-11#125#135#diseaseC0027627","pred":"source","obj":"DisGeNET5_gene_disease"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCoin-entities","color":"#c993ec","default":true},{"id":"LitCoin-sentences","color":"#93ecaf"},{"id":"LitCoin-entities-OrganismTaxon-PD","color":"#ec9593"},{"id":"LitCoin_Mondo","color":"#93aaec"},{"id":"LitCoin-GeneOrGeneProduct-v0","color":"#c4ec93"},{"id":"LitCoin-GeneOrGeneProduct-v2","color":"#ec93de"},{"id":"LitCoin-NCBITaxon-2","color":"#93ecdf"},{"id":"LitCoin-Disease-MeSH","color":"#ecc593"},{"id":"LitCoin-GeneOrGeneProduct-v3","color":"#ab93ec"},{"id":"LitCoin_Mondo_095","color":"#94ec93"},{"id":"LitCoin-MeSH-Disease-2","color":"#ec93ae"},{"id":"LitCoin_CellLine","color":"#93c8ec"},{"id":"LitCoin-MONDO_bioort2019","color":"#e2ec93"},{"id":"LitCoin-Chemical-MeSH-CHEBI","color":"#dc93ec"},{"id":"LitCoin-training-merged","color":"#93ecc2"},{"id":"DisGeNET5_gene_disease","color":"#eca893"}]}]}}