| Id |
Subject |
Object |
Predicate |
Lexical cue |
| TextSentencer_T1 |
0-112 |
Sentence |
denotes |
Zebrafish Plzf transcription factors enhance early type I IFN response induced by two non-enveloped RNA viruses. |
| TextSentencer_T2 |
113-333 |
Sentence |
denotes |
The BTB-POZ transcription factor Promyelocytic Leukemia Zinc Finger (PLZF, or ZBTB16) has been recently identified as a major factor regulating the induction of a subset of Interferon stimulated genes in human and mouse. |
| TextSentencer_T3 |
334-453 |
Sentence |
denotes |
We show that the two co-orthologues of PLZF found in zebrafish show distinct expression patterns, especially in larvae. |
| TextSentencer_T4 |
454-701 |
Sentence |
denotes |
Although zbtb16a/plzfa and zbtb16b/plzfb are not modulated by IFN produced during viral infection, their over-expression increases the level of the early type I IFN response, at a critical phase in the race between the virus and the host response. |
| TextSentencer_T5 |
702-868 |
Sentence |
denotes |
The effect of Plzfb on IFN induction was also detectable after cell infection by different non-enveloped RNA viruses, but not after infection by the rhabdovirus SVCV. |
| TextSentencer_T6 |
869-1059 |
Sentence |
denotes |
Our findings indicate that plzf implication in the regulation of type I IFN responses is conserved across vertebrates, but at multiple levels of the pathway and through different mechanisms. |
| T1 |
0-112 |
Sentence |
denotes |
Zebrafish Plzf transcription factors enhance early type I IFN response induced by two non-enveloped RNA viruses. |
| T2 |
113-333 |
Sentence |
denotes |
The BTB-POZ transcription factor Promyelocytic Leukemia Zinc Finger (PLZF, or ZBTB16) has been recently identified as a major factor regulating the induction of a subset of Interferon stimulated genes in human and mouse. |
| T3 |
334-453 |
Sentence |
denotes |
We show that the two co-orthologues of PLZF found in zebrafish show distinct expression patterns, especially in larvae. |
| T4 |
454-701 |
Sentence |
denotes |
Although zbtb16a/plzfa and zbtb16b/plzfb are not modulated by IFN produced during viral infection, their over-expression increases the level of the early type I IFN response, at a critical phase in the race between the virus and the host response. |
| T5 |
702-868 |
Sentence |
denotes |
The effect of Plzfb on IFN induction was also detectable after cell infection by different non-enveloped RNA viruses, but not after infection by the rhabdovirus SVCV. |
| T6 |
869-1059 |
Sentence |
denotes |
Our findings indicate that plzf implication in the regulation of type I IFN responses is conserved across vertebrates, but at multiple levels of the pathway and through different mechanisms. |
