PubMed:26684240 / 1168-1482 JSONTXT

{"project":"LitCoin-entities","denotations":[{"id":"11013","span":{"begin":9,"end":13},"obj":"GeneOrGeneProduct"},{"id":"11014","span":{"begin":14,"end":19},"obj":"SequenceVariant"},{"id":"11015","span":{"begin":24,"end":27},"obj":"DiseaseOrPhenotypicFeature"},{"id":"11016","span":{"begin":51,"end":55},"obj":"DiseaseOrPhenotypicFeature"},{"id":"11017","span":{"begin":72,"end":76},"obj":"GeneOrGeneProduct"},{"id":"11018","span":{"begin":77,"end":82},"obj":"SequenceVariant"},{"id":"11019","span":{"begin":87,"end":90},"obj":"DiseaseOrPhenotypicFeature"},{"id":"11020","span":{"begin":163,"end":171},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A43","pred":"db_id","subj":"11013","obj":"NCBIGene:673"},{"id":"A44","pred":"db_id","subj":"11014","obj":"DBSNP:rs113488022"},{"id":"A45","pred":"db_id","subj":"11015","obj":"MESH:D018358"},{"id":"A46","pred":"db_id","subj":"11016","obj":"MESH:D018358"},{"id":"A47","pred":"db_id","subj":"11017","obj":"NCBIGene:673"},{"id":"A48","pred":"db_id","subj":"11018","obj":"p.G593S"},{"id":"A49","pred":"db_id","subj":"11019","obj":"MESH:D018358"},{"id":"A50","pred":"db_id","subj":"11020","obj":"MESH:C535650"}],"namespaces":[{"prefix":"_base","uri":"https://w3id.org/biolink/vocab/"},{"prefix":"MESH","uri":"http://id.nlm.nih.gov/mesh/"},{"prefix":"NCBITaxon","uri":"https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id="},{"prefix":"NCBIGene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"OMIM","uri":"https://www.omim.org/entry/"},{"prefix":"DBSNP","uri":"https://www.ncbi.nlm.nih.gov/snp/"}],"text":"We found BRAF V600E (G1 NET from rectum and two G3 NETs from colon) and BRAF G593S (G2 NET from pancreas) missense mutations (9.1%) in an independent cohort of 44 GEP-NETs from the rectum (n = 26), colon (n = 7), pancreas (n = 4), small intestine (n = 3), stomach (n = 3) and appendix (n = 1) by Sanger sequencing."}

{"project":"LitCoin-sentences","denotations":[{"id":"T8","span":{"begin":0,"end":314},"obj":"Sentence"}],"text":"We found BRAF V600E (G1 NET from rectum and two G3 NETs from colon) and BRAF G593S (G2 NET from pancreas) missense mutations (9.1%) in an independent cohort of 44 GEP-NETs from the rectum (n = 26), colon (n = 7), pancreas (n = 4), small intestine (n = 3), stomach (n = 3) and appendix (n = 1) by Sanger sequencing."}

{"project":"LitCoin-SeqVar","denotations":[{"id":"T3","span":{"begin":14,"end":19},"obj":"SequenceVariant"},{"id":"T4","span":{"begin":77,"end":82},"obj":"SequenceVariant"}],"text":"We found BRAF V600E (G1 NET from rectum and two G3 NETs from colon) and BRAF G593S (G2 NET from pancreas) missense mutations (9.1%) in an independent cohort of 44 GEP-NETs from the rectum (n = 26), colon (n = 7), pancreas (n = 4), small intestine (n = 3), stomach (n = 3) and appendix (n = 1) by Sanger sequencing."}

{"project":"LitCoin-GeneOrGeneProduct-v2","denotations":[{"id":"T29","span":{"begin":9,"end":13},"obj":"GeneOrGeneProduct"},{"id":"T30","span":{"begin":24,"end":27},"obj":"GeneOrGeneProduct"},{"id":"T31","span":{"begin":72,"end":76},"obj":"GeneOrGeneProduct"},{"id":"T32","span":{"begin":87,"end":90},"obj":"GeneOrGeneProduct"},{"id":"T33","span":{"begin":231,"end":236},"obj":"GeneOrGeneProduct"}],"text":"We found BRAF V600E (G1 NET from rectum and two G3 NETs from colon) and BRAF G593S (G2 NET from pancreas) missense mutations (9.1%) in an independent cohort of 44 GEP-NETs from the rectum (n = 26), colon (n = 7), pancreas (n = 4), small intestine (n = 3), stomach (n = 3) and appendix (n = 1) by Sanger sequencing."}

{"project":"LitCoin-GeneOrGeneProduct-v0","denotations":[{"id":"T54","span":{"begin":9,"end":13},"obj":"GeneOrGeneProduct"},{"id":"T55","span":{"begin":24,"end":27},"obj":"GeneOrGeneProduct"},{"id":"T56","span":{"begin":48,"end":50},"obj":"GeneOrGeneProduct"},{"id":"T57","span":{"begin":51,"end":55},"obj":"GeneOrGeneProduct"},{"id":"T58","span":{"begin":72,"end":76},"obj":"GeneOrGeneProduct"},{"id":"T59","span":{"begin":87,"end":90},"obj":"GeneOrGeneProduct"},{"id":"T60","span":{"begin":106,"end":114},"obj":"GeneOrGeneProduct"},{"id":"T61","span":{"begin":115,"end":124},"obj":"GeneOrGeneProduct"},{"id":"T62","span":{"begin":167,"end":171},"obj":"GeneOrGeneProduct"},{"id":"T63","span":{"begin":189,"end":195},"obj":"GeneOrGeneProduct"},{"id":"T64","span":{"begin":231,"end":236},"obj":"GeneOrGeneProduct"},{"id":"T65","span":{"begin":237,"end":246},"obj":"GeneOrGeneProduct"}],"text":"We found BRAF V600E (G1 NET from rectum and two G3 NETs from colon) and BRAF G593S (G2 NET from pancreas) missense mutations (9.1%) in an independent cohort of 44 GEP-NETs from the rectum (n = 26), colon (n = 7), pancreas (n = 4), small intestine (n = 3), stomach (n = 3) and appendix (n = 1) by Sanger sequencing."}

{"project":"LitCoin-GeneOrGeneProduct-v3","denotations":[{"id":"T26","span":{"begin":9,"end":13},"obj":"GeneOrGeneProduct"},{"id":"T27","span":{"begin":24,"end":27},"obj":"GeneOrGeneProduct"},{"id":"T28","span":{"begin":72,"end":76},"obj":"GeneOrGeneProduct"},{"id":"T29","span":{"begin":87,"end":90},"obj":"GeneOrGeneProduct"}],"text":"We found BRAF V600E (G1 NET from rectum and two G3 NETs from colon) and BRAF G593S (G2 NET from pancreas) missense mutations (9.1%) in an independent cohort of 44 GEP-NETs from the rectum (n = 26), colon (n = 7), pancreas (n = 4), small intestine (n = 3), stomach (n = 3) and appendix (n = 1) by Sanger sequencing."}

{"project":"LitCoin_Mondo_095","denotations":[{"id":"T9","span":{"begin":96,"end":104},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T10","span":{"begin":213,"end":221},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A9","pred":"mondo_id","subj":"T9","obj":"0021040"},{"id":"A10","pred":"mondo_id","subj":"T10","obj":"0021040"}],"text":"We found BRAF V600E (G1 NET from rectum and two G3 NETs from colon) and BRAF G593S (G2 NET from pancreas) missense mutations (9.1%) in an independent cohort of 44 GEP-NETs from the rectum (n = 26), colon (n = 7), pancreas (n = 4), small intestine (n = 3), stomach (n = 3) and appendix (n = 1) by Sanger sequencing."}

{"project":"LitCoin-MeSH-Disease-2","denotations":[{"id":"T10","span":{"begin":24,"end":27},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T11","span":{"begin":51,"end":55},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T12","span":{"begin":87,"end":90},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T13","span":{"begin":163,"end":171},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A10","pred":"ID:","subj":"T10","obj":"DISEASE"},{"id":"A11","pred":"ID:","subj":"T11","obj":"DISEASE"},{"id":"A12","pred":"ID:","subj":"T12","obj":"DISEASE"},{"id":"A13","pred":"ID:","subj":"T13","obj":"DISEASE"}],"text":"We found BRAF V600E (G1 NET from rectum and two G3 NETs from colon) and BRAF G593S (G2 NET from pancreas) missense mutations (9.1%) in an independent cohort of 44 GEP-NETs from the rectum (n = 26), colon (n = 7), pancreas (n = 4), small intestine (n = 3), stomach (n = 3) and appendix (n = 1) by Sanger sequencing."}

{"project":"LitCoin-MONDO_bioort2019","denotations":[{"id":"T10","span":{"begin":24,"end":27},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T11","span":{"begin":51,"end":55},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T12","span":{"begin":87,"end":90},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T13","span":{"begin":163,"end":171},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A10","pred":"#label","subj":"T10","obj":"DISEASE"},{"id":"A11","pred":"#label","subj":"T11","obj":"DISEASE"},{"id":"A12","pred":"#label","subj":"T12","obj":"DISEASE"},{"id":"A13","pred":"#label","subj":"T13","obj":"DISEASE"}],"text":"We found BRAF V600E (G1 NET from rectum and two G3 NETs from colon) and BRAF G593S (G2 NET from pancreas) missense mutations (9.1%) in an independent cohort of 44 GEP-NETs from the rectum (n = 26), colon (n = 7), pancreas (n = 4), small intestine (n = 3), stomach (n = 3) and appendix (n = 1) by Sanger sequencing."}

{"project":"LitCoin-training-merged","denotations":[{"id":"T29","span":{"begin":87,"end":90},"obj":"GeneOrGeneProduct"},{"id":"T28","span":{"begin":72,"end":76},"obj":"GeneOrGeneProduct"},{"id":"T27","span":{"begin":24,"end":27},"obj":"GeneOrGeneProduct"},{"id":"T26","span":{"begin":9,"end":13},"obj":"GeneOrGeneProduct"},{"id":"T51763","span":{"begin":163,"end":171},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T89093","span":{"begin":87,"end":90},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T17041","span":{"begin":51,"end":55},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T54477","span":{"begin":24,"end":27},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T54782","span":{"begin":77,"end":82},"obj":"SequenceVariant"},{"id":"T91746","span":{"begin":14,"end":19},"obj":"SequenceVariant"}],"attributes":[{"id":"A13","pred":"#label","subj":"T51763","obj":"DISEASE"},{"id":"A12","pred":"#label","subj":"T89093","obj":"DISEASE"},{"id":"A11","pred":"#label","subj":"T17041","obj":"DISEASE"},{"id":"A10","pred":"#label","subj":"T54477","obj":"DISEASE"}],"text":"We found BRAF V600E (G1 NET from rectum and two G3 NETs from colon) and BRAF G593S (G2 NET from pancreas) missense mutations (9.1%) in an independent cohort of 44 GEP-NETs from the rectum (n = 26), colon (n = 7), pancreas (n = 4), small intestine (n = 3), stomach (n = 3) and appendix (n = 1) by Sanger sequencing."}