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PubMed:26269592 JSONTXT

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Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-81 Sentence denotes Signal Transduction and Intracellular Trafficking by the Interleukin 36 Receptor.
T2 82-237 Sentence denotes Improper signaling of the IL-36 receptor (IL-36R), a member of the IL-1 receptor family, has been associated with various inflammation-associated diseases.
T3 238-323 Sentence denotes However, the requirements for IL-36R signal transduction remain poorly characterized.
T4 324-418 Sentence denotes This work seeks to define the requirements for IL-36R signaling and intracellular trafficking.
T5 419-514 Sentence denotes In the absence of cognate agonists, IL-36R was endocytosed and recycled to the plasma membrane.
T6 515-591 Sentence denotes In the presence of IL-36, IL-36R increased accumulation in LAMP1+ lysosomes.
T7 592-746 Sentence denotes Endocytosis predominantly used a clathrin-mediated pathway, and the accumulation of the IL-36R in lysosomes did not result in increased receptor turnover.
T8 747-878 Sentence denotes The ubiquitin-binding Tollip protein contributed to IL-36R signaling and increased the accumulation of both subunits of the IL-36R.
T1 0-81 Sentence denotes Signal Transduction and Intracellular Trafficking by the Interleukin 36 Receptor.
T2 82-237 Sentence denotes Improper signaling of the IL-36 receptor (IL-36R), a member of the IL-1 receptor family, has been associated with various inflammation-associated diseases.
T3 238-323 Sentence denotes However, the requirements for IL-36R signal transduction remain poorly characterized.
T4 324-418 Sentence denotes This work seeks to define the requirements for IL-36R signaling and intracellular trafficking.
T5 419-514 Sentence denotes In the absence of cognate agonists, IL-36R was endocytosed and recycled to the plasma membrane.
T6 515-591 Sentence denotes In the presence of IL-36, IL-36R increased accumulation in LAMP1+ lysosomes.
T7 592-746 Sentence denotes Endocytosis predominantly used a clathrin-mediated pathway, and the accumulation of the IL-36R in lysosomes did not result in increased receptor turnover.
T8 747-878 Sentence denotes The ubiquitin-binding Tollip protein contributed to IL-36R signaling and increased the accumulation of both subunits of the IL-36R.

sentences

Id Subject Object Predicate Lexical cue
T1 0-81 Sentence denotes Signal Transduction and Intracellular Trafficking by the Interleukin 36 Receptor.
T2 82-237 Sentence denotes Improper signaling of the IL-36 receptor (IL-36R), a member of the IL-1 receptor family, has been associated with various inflammation-associated diseases.
T3 238-323 Sentence denotes However, the requirements for IL-36R signal transduction remain poorly characterized.
T4 324-418 Sentence denotes This work seeks to define the requirements for IL-36R signaling and intracellular trafficking.
T5 419-514 Sentence denotes In the absence of cognate agonists, IL-36R was endocytosed and recycled to the plasma membrane.
T6 515-591 Sentence denotes In the presence of IL-36, IL-36R increased accumulation in LAMP1+ lysosomes.
T7 592-746 Sentence denotes Endocytosis predominantly used a clathrin-mediated pathway, and the accumulation of the IL-36R in lysosomes did not result in increased receptor turnover.
T8 747-878 Sentence denotes The ubiquitin-binding Tollip protein contributed to IL-36R signaling and increased the accumulation of both subunits of the IL-36R.

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 204-216 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 24-37 Body_part denotes Intracellular http://purl.obolibrary.org/obo/GO_0005622
T2 392-405 Body_part denotes intracellular http://purl.obolibrary.org/obo/GO_0005622
T3 498-513 Body_part denotes plasma membrane http://purl.obolibrary.org/obo/GO_0005886
T4 581-590 Body_part denotes lysosomes http://purl.obolibrary.org/obo/GO_0005764
T5 690-699 Body_part denotes lysosomes http://purl.obolibrary.org/obo/GO_0005764