PubMed:25978997
Annnotations
Glycan-Motif
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 50-56 | https://glytoucan.org/Structures/Glycans/G32254QI | denotes | SSEA-4 |
| T2 | 50-56 | https://glytoucan.org/Structures/Glycans/G84263XI | denotes | SSEA-4 |
| T3 | 171-177 | https://glytoucan.org/Structures/Glycans/G32254QI | denotes | SSEA-4 |
| T4 | 171-177 | https://glytoucan.org/Structures/Glycans/G84263XI | denotes | SSEA-4 |
| T5 | 334-340 | https://glytoucan.org/Structures/Glycans/G32254QI | denotes | SSEA-4 |
| T6 | 334-340 | https://glytoucan.org/Structures/Glycans/G84263XI | denotes | SSEA-4 |
| T7 | 368-374 | https://glytoucan.org/Structures/Glycans/G32254QI | denotes | SSEA-4 |
| T8 | 368-374 | https://glytoucan.org/Structures/Glycans/G84263XI | denotes | SSEA-4 |
| T9 | 422-428 | https://glytoucan.org/Structures/Glycans/G32254QI | denotes | SSEA-4 |
| T10 | 422-428 | https://glytoucan.org/Structures/Glycans/G84263XI | denotes | SSEA-4 |
| T11 | 574-580 | https://glytoucan.org/Structures/Glycans/G32254QI | denotes | SSEA-4 |
| T12 | 574-580 | https://glytoucan.org/Structures/Glycans/G84263XI | denotes | SSEA-4 |
| T13 | 679-685 | https://glytoucan.org/Structures/Glycans/G32254QI | denotes | SSEA-4 |
| T14 | 679-685 | https://glytoucan.org/Structures/Glycans/G84263XI | denotes | SSEA-4 |
| T15 | 767-773 | https://glytoucan.org/Structures/Glycans/G32254QI | denotes | SSEA-4 |
| T16 | 767-773 | https://glytoucan.org/Structures/Glycans/G84263XI | denotes | SSEA-4 |
| T17 | 959-965 | https://glytoucan.org/Structures/Glycans/G32254QI | denotes | SSEA-4 |
| T18 | 959-965 | https://glytoucan.org/Structures/Glycans/G84263XI | denotes | SSEA-4 |
| T19 | 1029-1035 | https://glytoucan.org/Structures/Glycans/G32254QI | denotes | SSEA-4 |
| T20 | 1029-1035 | https://glytoucan.org/Structures/Glycans/G84263XI | denotes | SSEA-4 |
| T21 | 1259-1265 | https://glytoucan.org/Structures/Glycans/G32254QI | denotes | SSEA-4 |
| T22 | 1259-1265 | https://glytoucan.org/Structures/Glycans/G84263XI | denotes | SSEA-4 |
| T23 | 1376-1382 | https://glytoucan.org/Structures/Glycans/G32254QI | denotes | SSEA-4 |
| T24 | 1376-1382 | https://glytoucan.org/Structures/Glycans/G84263XI | denotes | SSEA-4 |
| T25 | 1472-1478 | https://glytoucan.org/Structures/Glycans/G32254QI | denotes | SSEA-4 |
| T26 | 1472-1478 | https://glytoucan.org/Structures/Glycans/G84263XI | denotes | SSEA-4 |
| T27 | 1549-1555 | https://glytoucan.org/Structures/Glycans/G32254QI | denotes | SSEA-4 |
| T28 | 1549-1555 | https://glytoucan.org/Structures/Glycans/G84263XI | denotes | SSEA-4 |
| T29 | 1671-1677 | https://glytoucan.org/Structures/Glycans/G32254QI | denotes | SSEA-4 |
| T30 | 1671-1677 | https://glytoucan.org/Structures/Glycans/G84263XI | denotes | SSEA-4 |
| T31 | 1796-1802 | https://glytoucan.org/Structures/Glycans/G32254QI | denotes | SSEA-4 |
| T32 | 1796-1802 | https://glytoucan.org/Structures/Glycans/G84263XI | denotes | SSEA-4 |
| T33 | 1939-1945 | https://glytoucan.org/Structures/Glycans/G32254QI | denotes | SSEA-4 |
| T34 | 1939-1945 | https://glytoucan.org/Structures/Glycans/G84263XI | denotes | SSEA-4 |
GlyCosmos6-Glycan-Motif-Image
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 50-56 | Glycan_Motif | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G84263XI|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G32254QI |
| T3 | 50-54 | Glycan_Motif | denotes | SSEA | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G99053DY|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G85497PI |
| T5 | 171-177 | Glycan_Motif | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G84263XI|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G32254QI |
| T7 | 171-175 | Glycan_Motif | denotes | SSEA | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G99053DY|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G85497PI |
| T9 | 334-340 | Glycan_Motif | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G84263XI|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G32254QI |
| T11 | 334-338 | Glycan_Motif | denotes | SSEA | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G99053DY|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G85497PI |
| T13 | 368-374 | Glycan_Motif | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G84263XI|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G32254QI |
| T15 | 368-372 | Glycan_Motif | denotes | SSEA | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G99053DY|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G85497PI |
| T17 | 422-428 | Glycan_Motif | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G84263XI|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G32254QI |
| T19 | 422-426 | Glycan_Motif | denotes | SSEA | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G99053DY|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G85497PI |
| T21 | 574-580 | Glycan_Motif | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G84263XI|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G32254QI |
| T23 | 574-578 | Glycan_Motif | denotes | SSEA | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G99053DY|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G85497PI |
| T25 | 679-685 | Glycan_Motif | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G84263XI|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G32254QI |
| T27 | 679-683 | Glycan_Motif | denotes | SSEA | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G99053DY|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G85497PI |
| T29 | 767-773 | Glycan_Motif | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G84263XI|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G32254QI |
| T31 | 767-771 | Glycan_Motif | denotes | SSEA | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G99053DY|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G85497PI |
| T33 | 959-965 | Glycan_Motif | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G84263XI|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G32254QI |
| T35 | 959-963 | Glycan_Motif | denotes | SSEA | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G99053DY|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G85497PI |
| T37 | 1029-1035 | Glycan_Motif | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G84263XI|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G32254QI |
| T39 | 1029-1033 | Glycan_Motif | denotes | SSEA | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G99053DY|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G85497PI |
| T41 | 1259-1265 | Glycan_Motif | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G84263XI|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G32254QI |
| T43 | 1259-1263 | Glycan_Motif | denotes | SSEA | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G99053DY|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G85497PI |
| T45 | 1376-1382 | Glycan_Motif | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G84263XI|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G32254QI |
| T47 | 1376-1380 | Glycan_Motif | denotes | SSEA | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G99053DY|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G85497PI |
| T49 | 1472-1478 | Glycan_Motif | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G84263XI|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G32254QI |
| T51 | 1472-1476 | Glycan_Motif | denotes | SSEA | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G99053DY|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G85497PI |
| T53 | 1549-1555 | Glycan_Motif | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G84263XI|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G32254QI |
| T55 | 1549-1553 | Glycan_Motif | denotes | SSEA | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G99053DY|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G85497PI |
| T57 | 1671-1677 | Glycan_Motif | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G84263XI|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G32254QI |
| T59 | 1671-1675 | Glycan_Motif | denotes | SSEA | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G99053DY|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G85497PI |
| T61 | 1796-1802 | Glycan_Motif | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G84263XI|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G32254QI |
| T63 | 1796-1800 | Glycan_Motif | denotes | SSEA | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G99053DY|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G85497PI |
| T65 | 1939-1945 | Glycan_Motif | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G84263XI|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G32254QI |
| T67 | 1939-1943 | Glycan_Motif | denotes | SSEA | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G99053DY|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G85497PI |
GlyCosmos6-Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 50-56 | https://glytoucan.org/Structures/Glycans/G32254QI | denotes | SSEA-4 |
| T2 | 50-56 | https://glytoucan.org/Structures/Glycans/G84263XI | denotes | SSEA-4 |
| T3 | 50-54 | https://glytoucan.org/Structures/Glycans/G85497PI | denotes | SSEA |
| T4 | 50-54 | https://glytoucan.org/Structures/Glycans/G99053DY | denotes | SSEA |
| T5 | 171-177 | https://glytoucan.org/Structures/Glycans/G32254QI | denotes | SSEA-4 |
| T6 | 171-177 | https://glytoucan.org/Structures/Glycans/G84263XI | denotes | SSEA-4 |
| T7 | 171-175 | https://glytoucan.org/Structures/Glycans/G85497PI | denotes | SSEA |
| T8 | 171-175 | https://glytoucan.org/Structures/Glycans/G99053DY | denotes | SSEA |
| T9 | 334-340 | https://glytoucan.org/Structures/Glycans/G32254QI | denotes | SSEA-4 |
| T10 | 334-340 | https://glytoucan.org/Structures/Glycans/G84263XI | denotes | SSEA-4 |
| T11 | 334-338 | https://glytoucan.org/Structures/Glycans/G85497PI | denotes | SSEA |
| T12 | 334-338 | https://glytoucan.org/Structures/Glycans/G99053DY | denotes | SSEA |
| T13 | 368-374 | https://glytoucan.org/Structures/Glycans/G32254QI | denotes | SSEA-4 |
| T14 | 368-374 | https://glytoucan.org/Structures/Glycans/G84263XI | denotes | SSEA-4 |
| T15 | 368-372 | https://glytoucan.org/Structures/Glycans/G85497PI | denotes | SSEA |
| T16 | 368-372 | https://glytoucan.org/Structures/Glycans/G99053DY | denotes | SSEA |
| T17 | 422-428 | https://glytoucan.org/Structures/Glycans/G32254QI | denotes | SSEA-4 |
| T18 | 422-428 | https://glytoucan.org/Structures/Glycans/G84263XI | denotes | SSEA-4 |
| T19 | 422-426 | https://glytoucan.org/Structures/Glycans/G85497PI | denotes | SSEA |
| T20 | 422-426 | https://glytoucan.org/Structures/Glycans/G99053DY | denotes | SSEA |
| T21 | 574-580 | https://glytoucan.org/Structures/Glycans/G32254QI | denotes | SSEA-4 |
| T22 | 574-580 | https://glytoucan.org/Structures/Glycans/G84263XI | denotes | SSEA-4 |
| T23 | 574-578 | https://glytoucan.org/Structures/Glycans/G85497PI | denotes | SSEA |
| T24 | 574-578 | https://glytoucan.org/Structures/Glycans/G99053DY | denotes | SSEA |
| T25 | 679-685 | https://glytoucan.org/Structures/Glycans/G32254QI | denotes | SSEA-4 |
| T26 | 679-685 | https://glytoucan.org/Structures/Glycans/G84263XI | denotes | SSEA-4 |
| T27 | 679-683 | https://glytoucan.org/Structures/Glycans/G85497PI | denotes | SSEA |
| T28 | 679-683 | https://glytoucan.org/Structures/Glycans/G99053DY | denotes | SSEA |
| T29 | 767-773 | https://glytoucan.org/Structures/Glycans/G32254QI | denotes | SSEA-4 |
| T30 | 767-773 | https://glytoucan.org/Structures/Glycans/G84263XI | denotes | SSEA-4 |
| T31 | 767-771 | https://glytoucan.org/Structures/Glycans/G85497PI | denotes | SSEA |
| T32 | 767-771 | https://glytoucan.org/Structures/Glycans/G99053DY | denotes | SSEA |
| T33 | 959-965 | https://glytoucan.org/Structures/Glycans/G32254QI | denotes | SSEA-4 |
| T34 | 959-965 | https://glytoucan.org/Structures/Glycans/G84263XI | denotes | SSEA-4 |
| T35 | 959-963 | https://glytoucan.org/Structures/Glycans/G85497PI | denotes | SSEA |
| T36 | 959-963 | https://glytoucan.org/Structures/Glycans/G99053DY | denotes | SSEA |
| T37 | 1029-1035 | https://glytoucan.org/Structures/Glycans/G32254QI | denotes | SSEA-4 |
| T38 | 1029-1035 | https://glytoucan.org/Structures/Glycans/G84263XI | denotes | SSEA-4 |
| T39 | 1029-1033 | https://glytoucan.org/Structures/Glycans/G85497PI | denotes | SSEA |
| T40 | 1029-1033 | https://glytoucan.org/Structures/Glycans/G99053DY | denotes | SSEA |
| T41 | 1259-1265 | https://glytoucan.org/Structures/Glycans/G32254QI | denotes | SSEA-4 |
| T42 | 1259-1265 | https://glytoucan.org/Structures/Glycans/G84263XI | denotes | SSEA-4 |
| T43 | 1259-1263 | https://glytoucan.org/Structures/Glycans/G85497PI | denotes | SSEA |
| T44 | 1259-1263 | https://glytoucan.org/Structures/Glycans/G99053DY | denotes | SSEA |
| T45 | 1376-1382 | https://glytoucan.org/Structures/Glycans/G32254QI | denotes | SSEA-4 |
| T46 | 1376-1382 | https://glytoucan.org/Structures/Glycans/G84263XI | denotes | SSEA-4 |
| T47 | 1376-1380 | https://glytoucan.org/Structures/Glycans/G85497PI | denotes | SSEA |
| T48 | 1376-1380 | https://glytoucan.org/Structures/Glycans/G99053DY | denotes | SSEA |
| T49 | 1472-1478 | https://glytoucan.org/Structures/Glycans/G32254QI | denotes | SSEA-4 |
| T50 | 1472-1478 | https://glytoucan.org/Structures/Glycans/G84263XI | denotes | SSEA-4 |
| T51 | 1472-1476 | https://glytoucan.org/Structures/Glycans/G85497PI | denotes | SSEA |
| T52 | 1472-1476 | https://glytoucan.org/Structures/Glycans/G99053DY | denotes | SSEA |
| T53 | 1549-1555 | https://glytoucan.org/Structures/Glycans/G32254QI | denotes | SSEA-4 |
| T54 | 1549-1555 | https://glytoucan.org/Structures/Glycans/G84263XI | denotes | SSEA-4 |
| T55 | 1549-1553 | https://glytoucan.org/Structures/Glycans/G85497PI | denotes | SSEA |
| T56 | 1549-1553 | https://glytoucan.org/Structures/Glycans/G99053DY | denotes | SSEA |
| T57 | 1671-1677 | https://glytoucan.org/Structures/Glycans/G32254QI | denotes | SSEA-4 |
| T58 | 1671-1677 | https://glytoucan.org/Structures/Glycans/G84263XI | denotes | SSEA-4 |
| T59 | 1671-1675 | https://glytoucan.org/Structures/Glycans/G85497PI | denotes | SSEA |
| T60 | 1671-1675 | https://glytoucan.org/Structures/Glycans/G99053DY | denotes | SSEA |
| T61 | 1796-1802 | https://glytoucan.org/Structures/Glycans/G32254QI | denotes | SSEA-4 |
| T62 | 1796-1802 | https://glytoucan.org/Structures/Glycans/G84263XI | denotes | SSEA-4 |
| T63 | 1796-1800 | https://glytoucan.org/Structures/Glycans/G85497PI | denotes | SSEA |
| T64 | 1796-1800 | https://glytoucan.org/Structures/Glycans/G99053DY | denotes | SSEA |
| T65 | 1939-1945 | https://glytoucan.org/Structures/Glycans/G32254QI | denotes | SSEA-4 |
| T66 | 1939-1945 | https://glytoucan.org/Structures/Glycans/G84263XI | denotes | SSEA-4 |
| T67 | 1939-1943 | https://glytoucan.org/Structures/Glycans/G85497PI | denotes | SSEA |
| T68 | 1939-1943 | https://glytoucan.org/Structures/Glycans/G99053DY | denotes | SSEA |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TextSentencer_T1 | 0-134 | Sentence | denotes | Expression of stage-specific embryonic antigen-4 (SSEA-4) defines spontaneous loss of epithelial phenotype in human solid tumor cells. |
| TextSentencer_T2 | 135-285 | Sentence | denotes | Stage-specific embryonic antigen-4 (SSEA-4) is a glycosphingolipid, which is overexpressed in some cancers and has been linked to disease progression. |
| TextSentencer_T3 | 286-398 | Sentence | denotes | However, little is known about the functions of SSEA-4 and the characteristics of SSEA-4 expressing tumor cells. |
| TextSentencer_T4 | 399-530 | Sentence | denotes | Our studies identified SSEA-4 expression on a subpopulation of cells in many solid tumor cell lines but not in leukemic cell lines. |
| TextSentencer_T5 | 531-739 | Sentence | denotes | Fluorescence-activated cell sorting-sorted SSEA-4(+) prostate cancer cells formed fibroblast-like colonies with limited cell-cell contacts, whereas SSEA-4(-) cells formed cobblestone-like epithelial colonies. |
| TextSentencer_T6 | 740-841 | Sentence | denotes | Only colonies derived from SSEA-4(+) cells were enriched for pluripotent embryonic stem cell markers. |
| TextSentencer_T7 | 842-1005 | Sentence | denotes | Moreover, major epithelial cell-associated markers Claudin-7, E-cadherin, ESRP1 and GRHL2 were down-regulated in the SSEA-4(+) fraction of DU145 and HCT-116 cells. |
| TextSentencer_T8 | 1006-1134 | Sentence | denotes | Similar to cell lines, SSEA-4(+) primary prostate tumor cells also showed down-regulation of epithelial cell-associated markers. |
| TextSentencer_T9 | 1135-1245 | Sentence | denotes | In addition, they showed up-regulation of epithelial-to-mesenchymal transition as well as mesenchymal markers. |
| TextSentencer_T10 | 1246-1462 | Sentence | denotes | Furthermore, SSEA-4(+) cells escape from adhesive colonies spontaneously and form invadopodia-like migratory structures, in which SSEA-4, cortactin as well as active pPI3K, pAkt and pSrc are enriched and colocalized. |
| TextSentencer_T11 | 1463-1642 | Sentence | denotes | Finally, SSEA-4(+) cells displayed strong tumorigenic ability and stable knockdown of SSEA-4 synthesis resulted in decreased cellular adhesion to different extracellular matrices. |
| TextSentencer_T12 | 1643-1762 | Sentence | denotes | In conclusion, we introduce SSEA-4 as a novel marker to identify heterogeneous, invasive subpopulations of tumor cells. |
| TextSentencer_T13 | 1763-2026 | Sentence | denotes | Moreover, increased cell-surface SSEA-4 expression is associated with the loss of cell-cell interactions and the gain of a migratory phenotype, suggesting an important role of SSEA-4 in cancer invasion by influencing cellular adhesion to the extracellular matrix. |
| T1 | 0-134 | Sentence | denotes | Expression of stage-specific embryonic antigen-4 (SSEA-4) defines spontaneous loss of epithelial phenotype in human solid tumor cells. |
| T2 | 135-285 | Sentence | denotes | Stage-specific embryonic antigen-4 (SSEA-4) is a glycosphingolipid, which is overexpressed in some cancers and has been linked to disease progression. |
| T3 | 286-398 | Sentence | denotes | However, little is known about the functions of SSEA-4 and the characteristics of SSEA-4 expressing tumor cells. |
| T4 | 399-530 | Sentence | denotes | Our studies identified SSEA-4 expression on a subpopulation of cells in many solid tumor cell lines but not in leukemic cell lines. |
| T5 | 531-739 | Sentence | denotes | Fluorescence-activated cell sorting-sorted SSEA-4(+) prostate cancer cells formed fibroblast-like colonies with limited cell-cell contacts, whereas SSEA-4(-) cells formed cobblestone-like epithelial colonies. |
| T6 | 740-841 | Sentence | denotes | Only colonies derived from SSEA-4(+) cells were enriched for pluripotent embryonic stem cell markers. |
| T7 | 842-1005 | Sentence | denotes | Moreover, major epithelial cell-associated markers Claudin-7, E-cadherin, ESRP1 and GRHL2 were down-regulated in the SSEA-4(+) fraction of DU145 and HCT-116 cells. |
| T8 | 1006-1134 | Sentence | denotes | Similar to cell lines, SSEA-4(+) primary prostate tumor cells also showed down-regulation of epithelial cell-associated markers. |
| T9 | 1135-1245 | Sentence | denotes | In addition, they showed up-regulation of epithelial-to-mesenchymal transition as well as mesenchymal markers. |
| T10 | 1246-1462 | Sentence | denotes | Furthermore, SSEA-4(+) cells escape from adhesive colonies spontaneously and form invadopodia-like migratory structures, in which SSEA-4, cortactin as well as active pPI3K, pAkt and pSrc are enriched and colocalized. |
| T11 | 1463-1642 | Sentence | denotes | Finally, SSEA-4(+) cells displayed strong tumorigenic ability and stable knockdown of SSEA-4 synthesis resulted in decreased cellular adhesion to different extracellular matrices. |
| T12 | 1643-1762 | Sentence | denotes | In conclusion, we introduce SSEA-4 as a novel marker to identify heterogeneous, invasive subpopulations of tumor cells. |
| T13 | 1763-2026 | Sentence | denotes | Moreover, increased cell-surface SSEA-4 expression is associated with the loss of cell-cell interactions and the gain of a migratory phenotype, suggesting an important role of SSEA-4 in cancer invasion by influencing cellular adhesion to the extracellular matrix. |
| T1 | 0-134 | Sentence | denotes | Expression of stage-specific embryonic antigen-4 (SSEA-4) defines spontaneous loss of epithelial phenotype in human solid tumor cells. |
| T2 | 135-285 | Sentence | denotes | Stage-specific embryonic antigen-4 (SSEA-4) is a glycosphingolipid, which is overexpressed in some cancers and has been linked to disease progression. |
| T3 | 286-398 | Sentence | denotes | However, little is known about the functions of SSEA-4 and the characteristics of SSEA-4 expressing tumor cells. |
| T4 | 399-530 | Sentence | denotes | Our studies identified SSEA-4 expression on a subpopulation of cells in many solid tumor cell lines but not in leukemic cell lines. |
| T5 | 531-739 | Sentence | denotes | Fluorescence-activated cell sorting-sorted SSEA-4(+) prostate cancer cells formed fibroblast-like colonies with limited cell-cell contacts, whereas SSEA-4(-) cells formed cobblestone-like epithelial colonies. |
| T6 | 740-841 | Sentence | denotes | Only colonies derived from SSEA-4(+) cells were enriched for pluripotent embryonic stem cell markers. |
| T7 | 842-1005 | Sentence | denotes | Moreover, major epithelial cell-associated markers Claudin-7, E-cadherin, ESRP1 and GRHL2 were down-regulated in the SSEA-4(+) fraction of DU145 and HCT-116 cells. |
| T8 | 1006-1134 | Sentence | denotes | Similar to cell lines, SSEA-4(+) primary prostate tumor cells also showed down-regulation of epithelial cell-associated markers. |
| T9 | 1135-1245 | Sentence | denotes | In addition, they showed up-regulation of epithelial-to-mesenchymal transition as well as mesenchymal markers. |
| T10 | 1246-1462 | Sentence | denotes | Furthermore, SSEA-4(+) cells escape from adhesive colonies spontaneously and form invadopodia-like migratory structures, in which SSEA-4, cortactin as well as active pPI3K, pAkt and pSrc are enriched and colocalized. |
| T11 | 1463-1642 | Sentence | denotes | Finally, SSEA-4(+) cells displayed strong tumorigenic ability and stable knockdown of SSEA-4 synthesis resulted in decreased cellular adhesion to different extracellular matrices. |
| T12 | 1643-1762 | Sentence | denotes | In conclusion, we introduce SSEA-4 as a novel marker to identify heterogeneous, invasive subpopulations of tumor cells. |
| T13 | 1763-2026 | Sentence | denotes | Moreover, increased cell-surface SSEA-4 expression is associated with the loss of cell-cell interactions and the gain of a migratory phenotype, suggesting an important role of SSEA-4 in cancer invasion by influencing cellular adhesion to the extracellular matrix. |
Glycosmos6-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 50-56 | http://www.glycoepitope.jp/epitopes/EP0044 | denotes | SSEA-4 |
| T2 | 171-177 | http://www.glycoepitope.jp/epitopes/EP0044 | denotes | SSEA-4 |
| T3 | 334-340 | http://www.glycoepitope.jp/epitopes/EP0044 | denotes | SSEA-4 |
| T4 | 368-374 | http://www.glycoepitope.jp/epitopes/EP0044 | denotes | SSEA-4 |
| T5 | 422-428 | http://www.glycoepitope.jp/epitopes/EP0044 | denotes | SSEA-4 |
| T6 | 574-580 | http://www.glycoepitope.jp/epitopes/EP0044 | denotes | SSEA-4 |
| T7 | 679-685 | http://www.glycoepitope.jp/epitopes/EP0044 | denotes | SSEA-4 |
| T8 | 767-773 | http://www.glycoepitope.jp/epitopes/EP0044 | denotes | SSEA-4 |
| T9 | 959-965 | http://www.glycoepitope.jp/epitopes/EP0044 | denotes | SSEA-4 |
| T10 | 1029-1035 | http://www.glycoepitope.jp/epitopes/EP0044 | denotes | SSEA-4 |
| T11 | 1259-1265 | http://www.glycoepitope.jp/epitopes/EP0044 | denotes | SSEA-4 |
| T12 | 1376-1382 | http://www.glycoepitope.jp/epitopes/EP0044 | denotes | SSEA-4 |
| T13 | 1472-1478 | http://www.glycoepitope.jp/epitopes/EP0044 | denotes | SSEA-4 |
| T14 | 1549-1555 | http://www.glycoepitope.jp/epitopes/EP0044 | denotes | SSEA-4 |
| T15 | 1671-1677 | http://www.glycoepitope.jp/epitopes/EP0044 | denotes | SSEA-4 |
| T16 | 1796-1802 | http://www.glycoepitope.jp/epitopes/EP0044 | denotes | SSEA-4 |
| T17 | 1939-1945 | http://www.glycoepitope.jp/epitopes/EP0044 | denotes | SSEA-4 |
Glycosmos6-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 584-592 | http://purl.obolibrary.org/obo/MAT_0000078 | denotes | prostate |
| T2 | 823-832 | http://purl.obolibrary.org/obo/MAT_0000185 | denotes | stem cell |
| T3 | 823-827 | http://purl.obolibrary.org/obo/MAT_0000239 | denotes | stem |
| T4 | 1047-1055 | http://purl.obolibrary.org/obo/MAT_0000078 | denotes | prostate |
GlycoBiology-FMA
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| _T1 | 116-121 | FMAID:85813 | denotes | solid |
| _T2 | 128-133 | FMAID:169002 | denotes | cells |
| _T3 | 128-133 | FMAID:68646 | denotes | cells |
| _T4 | 184-201 | FMAID:82819 | denotes | glycosphingolipid |
| _T5 | 184-201 | FMAID:82815 | denotes | glycosphingolipid |
| _T6 | 184-201 | FMAID:82813 | denotes | glycosphingolipid |
| _T7 | 184-201 | FMAID:196813 | denotes | glycosphingolipid |
| _T8 | 184-201 | FMAID:196815 | denotes | glycosphingolipid |
| _T9 | 184-201 | FMAID:196810 | denotes | glycosphingolipid |
| _T10 | 184-201 | FMAID:82818 | denotes | glycosphingolipid |
| _T11 | 184-201 | FMAID:196814 | denotes | glycosphingolipid |
| _T12 | 184-201 | FMAID:82812 | denotes | glycosphingolipid |
| _T13 | 184-201 | FMAID:196807 | denotes | glycosphingolipid |
| _T14 | 184-201 | FMAID:82817 | denotes | glycosphingolipid |
| _T15 | 184-201 | FMAID:196812 | denotes | glycosphingolipid |
| _T16 | 184-201 | FMAID:196809 | denotes | glycosphingolipid |
| _T17 | 184-201 | FMAID:82814 | denotes | glycosphingolipid |
| _T18 | 184-201 | FMAID:196806 | denotes | glycosphingolipid |
| _T19 | 184-201 | FMAID:82811 | denotes | glycosphingolipid |
| _T20 | 184-201 | FMAID:196808 | denotes | glycosphingolipid |
| _T21 | 392-397 | FMAID:169002 | denotes | cells |
| _T22 | 392-397 | FMAID:68646 | denotes | cells |
| _T23 | 462-467 | FMAID:169002 | denotes | cells |
| _T24 | 462-467 | FMAID:68646 | denotes | cells |
| _T25 | 476-481 | FMAID:85813 | denotes | solid |
| _T26 | 584-592 | FMAID:9600 | denotes | prostate |
| _T27 | 584-592 | FMAID:97485 | denotes | prostate |
| _T28 | 600-605 | FMAID:68646 | denotes | cells |
| _T29 | 600-605 | FMAID:169002 | denotes | cells |
| _T30 | 613-623 | FMAID:162340 | denotes | fibroblast |
| _T31 | 613-623 | FMAID:63877 | denotes | fibroblast |
| _T32 | 689-694 | FMAID:68646 | denotes | cells |
| _T33 | 689-694 | FMAID:169002 | denotes | cells |
| _T34 | 777-782 | FMAID:169002 | denotes | cells |
| _T35 | 777-782 | FMAID:68646 | denotes | cells |
| _T36 | 801-832 | FMAID:171412 | denotes | pluripotent embryonic stem cell |
| _T37 | 801-832 | FMAID:70570 | denotes | pluripotent embryonic stem cell |
| _T38 | 813-832 | FMAID:196840 | denotes | embryonic stem cell |
| _T39 | 813-832 | FMAID:82841 | denotes | embryonic stem cell |
| _T40 | 823-832 | FMAID:63368 | denotes | stem cell |
| _T41 | 823-832 | FMAID:167693 | denotes | stem cell |
| _T42 | 858-873 | FMAID:83514 | denotes | epithelial cell |
| _T43 | 858-873 | FMAID:165731 | denotes | epithelial cell |
| _T44 | 858-873 | FMAID:67799 | denotes | epithelial cell |
| _T45 | 858-873 | FMAID:66768 | denotes | epithelial cell |
| _T46 | 858-873 | FMAID:197786 | denotes | epithelial cell |
| _T47 | 858-873 | FMAID:165528 | denotes | epithelial cell |
| _T48 | 858-873 | FMAID:67559 | denotes | epithelial cell |
| _T49 | 858-873 | FMAID:169653 | denotes | epithelial cell |
| _T50 | 858-873 | FMAID:164922 | denotes | epithelial cell |
| _T51 | 858-873 | FMAID:69075 | denotes | epithelial cell |
| _T52 | 858-873 | FMAID:169652 | denotes | epithelial cell |
| _T53 | 858-873 | FMAID:69074 | denotes | epithelial cell |
| _T54 | 904-914 | FMAID:165239 | denotes | E-cadherin |
| _T55 | 904-914 | FMAID:61792 | denotes | E-cadherin |
| _T56 | 904-914 | FMAID:165240 | denotes | E-cadherin |
| _T57 | 904-914 | FMAID:61793 | denotes | E-cadherin |
| _T58 | 904-914 | FMAID:61794 | denotes | E-cadherin |
| _T59 | 904-914 | FMAID:165241 | denotes | E-cadherin |
| _T60 | 906-914 | FMAID:61790 | denotes | cadherin |
| _T61 | 906-914 | FMAID:165235 | denotes | cadherin |
| _T62 | 999-1004 | FMAID:68646 | denotes | cells |
| _T63 | 999-1004 | FMAID:169002 | denotes | cells |
| _T64 | 1047-1055 | FMAID:9600 | denotes | prostate |
| _T65 | 1047-1055 | FMAID:97485 | denotes | prostate |
| _T66 | 1062-1067 | FMAID:68646 | denotes | cells |
| _T67 | 1062-1067 | FMAID:169002 | denotes | cells |
| _T68 | 1099-1114 | FMAID:165528 | denotes | epithelial cell |
| _T69 | 1099-1114 | FMAID:165731 | denotes | epithelial cell |
| _T70 | 1099-1114 | FMAID:67559 | denotes | epithelial cell |
| _T71 | 1099-1114 | FMAID:197786 | denotes | epithelial cell |
| _T72 | 1099-1114 | FMAID:67799 | denotes | epithelial cell |
| _T73 | 1099-1114 | FMAID:169652 | denotes | epithelial cell |
| _T74 | 1099-1114 | FMAID:169653 | denotes | epithelial cell |
| _T75 | 1099-1114 | FMAID:69075 | denotes | epithelial cell |
| _T76 | 1099-1114 | FMAID:164922 | denotes | epithelial cell |
| _T77 | 1099-1114 | FMAID:69074 | denotes | epithelial cell |
| _T78 | 1099-1114 | FMAID:66768 | denotes | epithelial cell |
| _T79 | 1099-1114 | FMAID:83514 | denotes | epithelial cell |
| _T80 | 1203-1213 | FMAID:171495 | denotes | transition |
| _T81 | 1203-1213 | FMAID:70637 | denotes | transition |
| _T82 | 1269-1274 | FMAID:68646 | denotes | cells |
| _T83 | 1269-1274 | FMAID:169002 | denotes | cells |
| _T84 | 1482-1487 | FMAID:68646 | denotes | cells |
| _T85 | 1482-1487 | FMAID:169002 | denotes | cells |
| _T86 | 1619-1641 | FMAID:265717 | denotes | extracellular matrices |
| _T87 | 1756-1761 | FMAID:169002 | denotes | cells |
| _T88 | 1756-1761 | FMAID:68646 | denotes | cells |
| _T89 | 1783-1795 | FMAID:212684 | denotes | cell-surface |
| _T90 | 1783-1795 | FMAID:200942 | denotes | cell-surface |
| _T91 | 1788-1795 | FMAID:50594 | denotes | surface |
| _T92 | 1788-1795 | FMAID:146300 | denotes | surface |
| _T93 | 1876-1880 | FMAID:216818 | denotes | gain |
| _T94 | 2005-2025 | FMAID:265717 | denotes | extracellular matrix |
| _T95 | 2005-2025 | FMAID:165194 | denotes | extracellular matrix |
uniprot-human
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 893-902 | http://www.uniprot.org/uniprot/O95471 | denotes | Claudin-7 |
| T2 | 904-914 | http://www.uniprot.org/uniprot/P12830 | denotes | E-cadherin |
| T3 | 916-921 | http://www.uniprot.org/uniprot/Q6NXG1 | denotes | ESRP1 |
| T4 | 926-931 | http://www.uniprot.org/uniprot/Q6ISB3 | denotes | GRHL2 |
uniprot-mouse
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 893-902 | http://www.uniprot.org/uniprot/Q9Z261 | denotes | Claudin-7 |
| T2 | 904-914 | http://www.uniprot.org/uniprot/P09803 | denotes | E-cadherin |
GlycoBiology-NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 128-133 | http://purl.bioontology.org/ontology/STY/T025 | denotes | cells |
| T2 | 234-241 | http://purl.bioontology.org/ontology/NCBITAXON/6754 | denotes | cancers |
| T3 | 392-397 | http://purl.bioontology.org/ontology/STY/T025 | denotes | cells |
| T4 | 462-467 | http://purl.bioontology.org/ontology/STY/T025 | denotes | cells |
| T5 | 471-475 | http://purl.bioontology.org/ontology/NCBITAXON/9973 | denotes | many |
| T6 | 593-599 | http://purl.bioontology.org/ontology/NCBITAXON/6754 | denotes | cancer |
| T7 | 600-605 | http://purl.bioontology.org/ontology/STY/T025 | denotes | cells |
| T8 | 689-694 | http://purl.bioontology.org/ontology/STY/T025 | denotes | cells |
| T9 | 777-782 | http://purl.bioontology.org/ontology/STY/T025 | denotes | cells |
| T10 | 999-1004 | http://purl.bioontology.org/ontology/STY/T025 | denotes | cells |
| T11 | 1062-1067 | http://purl.bioontology.org/ontology/STY/T025 | denotes | cells |
| T12 | 1269-1274 | http://purl.bioontology.org/ontology/STY/T025 | denotes | cells |
| T13 | 1482-1487 | http://purl.bioontology.org/ontology/STY/T025 | denotes | cells |
| T14 | 1708-1721 | http://purl.bioontology.org/ontology/NCBITAXON/691256 | denotes | heterogeneous |
| T15 | 1708-1721 | http://purl.bioontology.org/ontology/NCBITAXON/1113441 | denotes | heterogeneous |
| T16 | 1756-1761 | http://purl.bioontology.org/ontology/STY/T025 | denotes | cells |
| T17 | 1949-1955 | http://purl.bioontology.org/ontology/NCBITAXON/6754 | denotes | cancer |
GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 544-558 | http://purl.obolibrary.org/obo/GO_0001775 | denotes | activated cell |
| T2 | 942-951 | http://purl.obolibrary.org/obo/GO_0065007 | denotes | regulated |
| T3 | 1085-1095 | http://purl.obolibrary.org/obo/GO_0065007 | denotes | regulation |
| T4 | 1163-1173 | http://purl.obolibrary.org/obo/GO_0065007 | denotes | regulation |
| T5 | 1163-1213 | http://purl.obolibrary.org/obo/GO_0010717 | denotes | regulation of epithelial-to-mesenchymal transition |
| T6 | 1163-1213 | http://purl.obolibrary.org/obo/GO_0010719 | denotes | regulation of epithelial-to-mesenchymal transition |
| T7 | 1163-1213 | http://purl.obolibrary.org/obo/GO_0010718 | denotes | regulation of epithelial-to-mesenchymal transition |
| T8 | 1163-1213 | http://purl.obolibrary.org/obo/GO_2000084 | denotes | regulation of epithelial-to-mesenchymal transition |
| T9 | 1177-1213 | http://purl.obolibrary.org/obo/GO_0060231 | denotes | epithelial-to-mesenchymal transition |
| T10 | 1177-1213 | http://purl.obolibrary.org/obo/GO_0001837 | denotes | epithelial-to-mesenchymal transition |
| T11 | 1177-1213 | http://purl.obolibrary.org/obo/GO_0061261 | denotes | epithelial-to-mesenchymal transition |
| T12 | 1177-1213 | http://purl.obolibrary.org/obo/GO_0003337 | denotes | epithelial-to-mesenchymal transition |
| T13 | 1177-1213 | http://purl.obolibrary.org/obo/GO_0060317 | denotes | epithelial-to-mesenchymal transition |
| T14 | 1556-1565 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | synthesis |
| T15 | 1588-1596 | http://purl.obolibrary.org/obo/GO_0007349 | denotes | cellular |
| T16 | 1980-1988 | http://purl.obolibrary.org/obo/GO_0007349 | denotes | cellular |
GO-CC
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 128-133 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T2 | 392-397 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T3 | 462-467 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T4 | 600-605 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T5 | 689-694 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T6 | 777-782 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T7 | 999-1004 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T8 | 1062-1067 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T9 | 1269-1274 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T10 | 1482-1487 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T11 | 488-492 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T12 | 519-523 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T13 | 554-558 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T14 | 651-655 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T15 | 656-660 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T16 | 828-832 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T17 | 869-873 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T18 | 1017-1021 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T19 | 1110-1114 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T20 | 1783-1787 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T21 | 1845-1849 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T22 | 1850-1854 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T23 | 869-884 | http://purl.obolibrary.org/obo/GO_0009986 | denotes | cell-associated |
| T24 | 1110-1125 | http://purl.obolibrary.org/obo/GO_0009986 | denotes | cell-associated |
| T25 | 1619-1632 | http://purl.obolibrary.org/obo/GO_0005576 | denotes | extracellular |
| T26 | 2005-2018 | http://purl.obolibrary.org/obo/GO_0005576 | denotes | extracellular |
| T27 | 1783-1795 | http://purl.obolibrary.org/obo/GO_0009986 | denotes | cell-surface |
| T28 | 2005-2025 | http://purl.obolibrary.org/obo/GO_0031012 | denotes | extracellular matrix |
UBERON-AE
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 1191-1202 | http://purl.obolibrary.org/obo/UBERON_0003104 | denotes | mesenchymal |
| T2 | 1225-1236 | http://purl.obolibrary.org/obo/UBERON_0003104 | denotes | mesenchymal |
GlycoBiology-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 584-592 | http://purl.obolibrary.org/obo/MAT_0000078 | denotes | prostate |
| T2 | 651-660 | http://purl.obolibrary.org/obo/MAT_0000083 | denotes | cell-cell |
| T3 | 823-827 | http://purl.obolibrary.org/obo/MAT_0000239 | denotes | stem |
| T4 | 823-832 | http://purl.obolibrary.org/obo/MAT_0000185 | denotes | stem cell |
| T5 | 1047-1055 | http://purl.obolibrary.org/obo/MAT_0000078 | denotes | prostate |
| T6 | 1845-1854 | http://purl.obolibrary.org/obo/MAT_0000083 | denotes | cell-cell |
GlycoBiology-Epitope
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-GlycoEpitope-B_T1 | 50-56 | http://www.glycoepitope.jp/epitopes/EP0044 | denotes | SSEA-4 |
| PD-GlycoEpitope-B_T2 | 171-177 | http://www.glycoepitope.jp/epitopes/EP0044 | denotes | SSEA-4 |
| PD-GlycoEpitope-B_T3 | 334-340 | http://www.glycoepitope.jp/epitopes/EP0044 | denotes | SSEA-4 |
| PD-GlycoEpitope-B_T4 | 368-374 | http://www.glycoepitope.jp/epitopes/EP0044 | denotes | SSEA-4 |
| PD-GlycoEpitope-B_T5 | 422-428 | http://www.glycoepitope.jp/epitopes/EP0044 | denotes | SSEA-4 |
| PD-GlycoEpitope-B_T6 | 574-580 | http://www.glycoepitope.jp/epitopes/EP0044 | denotes | SSEA-4 |
| PD-GlycoEpitope-B_T7 | 679-685 | http://www.glycoepitope.jp/epitopes/EP0044 | denotes | SSEA-4 |
| PD-GlycoEpitope-B_T8 | 767-773 | http://www.glycoepitope.jp/epitopes/EP0044 | denotes | SSEA-4 |
| PD-GlycoEpitope-B_T9 | 959-965 | http://www.glycoepitope.jp/epitopes/EP0044 | denotes | SSEA-4 |
| PD-GlycoEpitope-B_T10 | 1029-1035 | http://www.glycoepitope.jp/epitopes/EP0044 | denotes | SSEA-4 |
| PD-GlycoEpitope-B_T11 | 1259-1265 | http://www.glycoepitope.jp/epitopes/EP0044 | denotes | SSEA-4 |
| PD-GlycoEpitope-B_T12 | 1376-1382 | http://www.glycoepitope.jp/epitopes/EP0044 | denotes | SSEA-4 |
| PD-GlycoEpitope-B_T13 | 1472-1478 | http://www.glycoepitope.jp/epitopes/EP0044 | denotes | SSEA-4 |
| PD-GlycoEpitope-B_T14 | 1549-1555 | http://www.glycoepitope.jp/epitopes/EP0044 | denotes | SSEA-4 |
| PD-GlycoEpitope-B_T15 | 1671-1677 | http://www.glycoepitope.jp/epitopes/EP0044 | denotes | SSEA-4 |
| PD-GlycoEpitope-B_T16 | 1796-1802 | http://www.glycoepitope.jp/epitopes/EP0044 | denotes | SSEA-4 |
| PD-GlycoEpitope-B_T17 | 1939-1945 | http://www.glycoepitope.jp/epitopes/EP0044 | denotes | SSEA-4 |
performance-test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-UBERON-AE-B_T1 | 1191-1202 | http://purl.obolibrary.org/obo/UBERON_0003104 | denotes | mesenchymal |
| PD-UBERON-AE-B_T2 | 1225-1236 | http://purl.obolibrary.org/obo/UBERON_0003104 | denotes | mesenchymal |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 122-127 | Disease | denotes | tumor | http://purl.obolibrary.org/obo/MONDO_0005070 |
| T2 | 386-391 | Disease | denotes | tumor | http://purl.obolibrary.org/obo/MONDO_0005070 |
| T3 | 482-487 | Disease | denotes | tumor | http://purl.obolibrary.org/obo/MONDO_0005070 |
| T4 | 584-599 | Disease | denotes | prostate cancer | http://purl.obolibrary.org/obo/MONDO_0008315 |
| T5 | 1047-1061 | Disease | denotes | prostate tumor | http://purl.obolibrary.org/obo/MONDO_0021259 |
| T6 | 1750-1755 | Disease | denotes | tumor | http://purl.obolibrary.org/obo/MONDO_0005070 |
| T7 | 1949-1955 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
HP-phenotype
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 122-127 | Phenotype | denotes | tumor | HP:0002664 |
| T2 | 386-391 | Phenotype | denotes | tumor | HP:0002664 |
| T3 | 482-487 | Phenotype | denotes | tumor | HP:0002664 |
| T4 | 584-599 | Phenotype | denotes | prostate cancer | HP:0012125 |
| T5 | 1056-1061 | Phenotype | denotes | tumor | HP:0002664 |
| T6 | 1750-1755 | Phenotype | denotes | tumor | HP:0002664 |
| T7 | 1949-1955 | Phenotype | denotes | cancer | HP:0002664 |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 50-56 | Glycan | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84263XI |
| T2 | 171-177 | Glycan | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84263XI |
| T3 | 334-340 | Glycan | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84263XI |
| T4 | 368-374 | Glycan | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84263XI |
| T5 | 422-428 | Glycan | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84263XI |
| T6 | 574-580 | Glycan | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84263XI |
| T7 | 679-685 | Glycan | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84263XI |
| T8 | 767-773 | Glycan | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84263XI |
| T9 | 959-965 | Glycan | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84263XI |
| T10 | 1029-1035 | Glycan | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84263XI |
| T11 | 1259-1265 | Glycan | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84263XI |
| T12 | 1376-1382 | Glycan | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84263XI |
| T13 | 1472-1478 | Glycan | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84263XI |
| T14 | 1549-1555 | Glycan | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84263XI |
| T15 | 1671-1677 | Glycan | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84263XI |
| T16 | 1796-1802 | Glycan | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84263XI |
| T17 | 1939-1945 | Glycan | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84263XI |
GlyCosmos15-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 122-127 | Phenotype | denotes | tumor | HP:0002664 |
| T2 | 386-391 | Phenotype | denotes | tumor | HP:0002664 |
| T3 | 482-487 | Phenotype | denotes | tumor | HP:0002664 |
| T4 | 584-599 | Phenotype | denotes | prostate cancer | HP:0012125 |
| T5 | 1056-1061 | Phenotype | denotes | tumor | HP:0002664 |
| T6 | 1750-1755 | Phenotype | denotes | tumor | HP:0002664 |
| T7 | 1949-1955 | Phenotype | denotes | cancer | HP:0002664 |
GlyCosmos15-CL
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 122-133 | Cell | denotes | tumor cells | http://purl.obolibrary.org/obo/CL:0001063 |
| T2 | 386-397 | Cell | denotes | tumor cells | http://purl.obolibrary.org/obo/CL:0001063 |
| T3 | 482-492 | Cell | denotes | tumor cell | http://purl.obolibrary.org/obo/CL:0001063 |
| T4 | 593-605 | Cell | denotes | cancer cells | http://purl.obolibrary.org/obo/CL:0001064 |
| T5 | 613-623 | Cell | denotes | fibroblast | http://purl.obolibrary.org/obo/CL:0000057 |
| T6 | 813-832 | Cell | denotes | embryonic stem cell | http://purl.obolibrary.org/obo/CL:0002322 |
| T7 | 823-832 | Cell | denotes | stem cell | http://purl.obolibrary.org/obo/CL:0000034 |
| T8 | 858-873 | Cell | denotes | epithelial cell | http://purl.obolibrary.org/obo/CL:0000066 |
| T9 | 1056-1067 | Cell | denotes | tumor cells | http://purl.obolibrary.org/obo/CL:0001063 |
| T10 | 1099-1114 | Cell | denotes | epithelial cell | http://purl.obolibrary.org/obo/CL:0000066 |
| T11 | 1750-1761 | Cell | denotes | tumor cells | http://purl.obolibrary.org/obo/CL:0001063 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 584-592 | Body_part | denotes | prostate | http://purl.obolibrary.org/obo/UBERON_0002367 |
| T2 | 613-623 | Body_part | denotes | fibroblast | http://purl.obolibrary.org/obo/CL_0000057 |
| T3 | 823-832 | Body_part | denotes | stem cell | http://purl.obolibrary.org/obo/CL_0000034 |
| T4 | 858-873 | Body_part | denotes | epithelial cell | http://purl.obolibrary.org/obo/CL_0000066 |
| T5 | 1047-1055 | Body_part | denotes | prostate | http://purl.obolibrary.org/obo/UBERON_0002367 |
| T6 | 1099-1114 | Body_part | denotes | epithelial cell | http://purl.obolibrary.org/obo/CL_0000066 |
| T7 | 1619-1632 | Body_part | denotes | extracellular | http://purl.obolibrary.org/obo/GO_0005576 |
| T8 | 2005-2025 | Body_part | denotes | extracellular matrix | http://purl.obolibrary.org/obo/GO_0031012 |
GlyCosmos15-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 584-592 | Body_part | denotes | prostate | http://purl.obolibrary.org/obo/MAT_0000078 |
| T2 | 823-832 | Body_part | denotes | stem cell | http://purl.obolibrary.org/obo/MAT_0000185 |
| T3 | 1047-1055 | Body_part | denotes | prostate | http://purl.obolibrary.org/obo/MAT_0000078 |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TextSentencer_T1 | 0-134 | Sentence | denotes | Expression of stage-specific embryonic antigen-4 (SSEA-4) defines spontaneous loss of epithelial phenotype in human solid tumor cells. |
| TextSentencer_T2 | 135-285 | Sentence | denotes | Stage-specific embryonic antigen-4 (SSEA-4) is a glycosphingolipid, which is overexpressed in some cancers and has been linked to disease progression. |
| TextSentencer_T3 | 286-398 | Sentence | denotes | However, little is known about the functions of SSEA-4 and the characteristics of SSEA-4 expressing tumor cells. |
| TextSentencer_T4 | 399-530 | Sentence | denotes | Our studies identified SSEA-4 expression on a subpopulation of cells in many solid tumor cell lines but not in leukemic cell lines. |
| TextSentencer_T5 | 531-739 | Sentence | denotes | Fluorescence-activated cell sorting-sorted SSEA-4(+) prostate cancer cells formed fibroblast-like colonies with limited cell-cell contacts, whereas SSEA-4(-) cells formed cobblestone-like epithelial colonies. |
| TextSentencer_T6 | 740-841 | Sentence | denotes | Only colonies derived from SSEA-4(+) cells were enriched for pluripotent embryonic stem cell markers. |
| TextSentencer_T7 | 842-1005 | Sentence | denotes | Moreover, major epithelial cell-associated markers Claudin-7, E-cadherin, ESRP1 and GRHL2 were down-regulated in the SSEA-4(+) fraction of DU145 and HCT-116 cells. |
| TextSentencer_T8 | 1006-1134 | Sentence | denotes | Similar to cell lines, SSEA-4(+) primary prostate tumor cells also showed down-regulation of epithelial cell-associated markers. |
| TextSentencer_T9 | 1135-1245 | Sentence | denotes | In addition, they showed up-regulation of epithelial-to-mesenchymal transition as well as mesenchymal markers. |
| TextSentencer_T10 | 1246-1462 | Sentence | denotes | Furthermore, SSEA-4(+) cells escape from adhesive colonies spontaneously and form invadopodia-like migratory structures, in which SSEA-4, cortactin as well as active pPI3K, pAkt and pSrc are enriched and colocalized. |
| TextSentencer_T11 | 1463-1642 | Sentence | denotes | Finally, SSEA-4(+) cells displayed strong tumorigenic ability and stable knockdown of SSEA-4 synthesis resulted in decreased cellular adhesion to different extracellular matrices. |
| TextSentencer_T12 | 1643-1762 | Sentence | denotes | In conclusion, we introduce SSEA-4 as a novel marker to identify heterogeneous, invasive subpopulations of tumor cells. |
| TextSentencer_T13 | 1763-2026 | Sentence | denotes | Moreover, increased cell-surface SSEA-4 expression is associated with the loss of cell-cell interactions and the gain of a migratory phenotype, suggesting an important role of SSEA-4 in cancer invasion by influencing cellular adhesion to the extracellular matrix. |
| T1 | 0-134 | Sentence | denotes | Expression of stage-specific embryonic antigen-4 (SSEA-4) defines spontaneous loss of epithelial phenotype in human solid tumor cells. |
| T2 | 135-285 | Sentence | denotes | Stage-specific embryonic antigen-4 (SSEA-4) is a glycosphingolipid, which is overexpressed in some cancers and has been linked to disease progression. |
| T3 | 286-398 | Sentence | denotes | However, little is known about the functions of SSEA-4 and the characteristics of SSEA-4 expressing tumor cells. |
| T4 | 399-530 | Sentence | denotes | Our studies identified SSEA-4 expression on a subpopulation of cells in many solid tumor cell lines but not in leukemic cell lines. |
| T5 | 531-739 | Sentence | denotes | Fluorescence-activated cell sorting-sorted SSEA-4(+) prostate cancer cells formed fibroblast-like colonies with limited cell-cell contacts, whereas SSEA-4(-) cells formed cobblestone-like epithelial colonies. |
| T6 | 740-841 | Sentence | denotes | Only colonies derived from SSEA-4(+) cells were enriched for pluripotent embryonic stem cell markers. |
| T7 | 842-1005 | Sentence | denotes | Moreover, major epithelial cell-associated markers Claudin-7, E-cadherin, ESRP1 and GRHL2 were down-regulated in the SSEA-4(+) fraction of DU145 and HCT-116 cells. |
| T8 | 1006-1134 | Sentence | denotes | Similar to cell lines, SSEA-4(+) primary prostate tumor cells also showed down-regulation of epithelial cell-associated markers. |
| T9 | 1135-1245 | Sentence | denotes | In addition, they showed up-regulation of epithelial-to-mesenchymal transition as well as mesenchymal markers. |
| T10 | 1246-1462 | Sentence | denotes | Furthermore, SSEA-4(+) cells escape from adhesive colonies spontaneously and form invadopodia-like migratory structures, in which SSEA-4, cortactin as well as active pPI3K, pAkt and pSrc are enriched and colocalized. |
| T11 | 1463-1642 | Sentence | denotes | Finally, SSEA-4(+) cells displayed strong tumorigenic ability and stable knockdown of SSEA-4 synthesis resulted in decreased cellular adhesion to different extracellular matrices. |
| T12 | 1643-1762 | Sentence | denotes | In conclusion, we introduce SSEA-4 as a novel marker to identify heterogeneous, invasive subpopulations of tumor cells. |
| T13 | 1763-2026 | Sentence | denotes | Moreover, increased cell-surface SSEA-4 expression is associated with the loss of cell-cell interactions and the gain of a migratory phenotype, suggesting an important role of SSEA-4 in cancer invasion by influencing cellular adhesion to the extracellular matrix. |
| T1 | 0-134 | Sentence | denotes | Expression of stage-specific embryonic antigen-4 (SSEA-4) defines spontaneous loss of epithelial phenotype in human solid tumor cells. |
| T2 | 135-285 | Sentence | denotes | Stage-specific embryonic antigen-4 (SSEA-4) is a glycosphingolipid, which is overexpressed in some cancers and has been linked to disease progression. |
| T3 | 286-398 | Sentence | denotes | However, little is known about the functions of SSEA-4 and the characteristics of SSEA-4 expressing tumor cells. |
| T4 | 399-530 | Sentence | denotes | Our studies identified SSEA-4 expression on a subpopulation of cells in many solid tumor cell lines but not in leukemic cell lines. |
| T5 | 531-739 | Sentence | denotes | Fluorescence-activated cell sorting-sorted SSEA-4(+) prostate cancer cells formed fibroblast-like colonies with limited cell-cell contacts, whereas SSEA-4(-) cells formed cobblestone-like epithelial colonies. |
| T6 | 740-841 | Sentence | denotes | Only colonies derived from SSEA-4(+) cells were enriched for pluripotent embryonic stem cell markers. |
| T7 | 842-1005 | Sentence | denotes | Moreover, major epithelial cell-associated markers Claudin-7, E-cadherin, ESRP1 and GRHL2 were down-regulated in the SSEA-4(+) fraction of DU145 and HCT-116 cells. |
| T8 | 1006-1134 | Sentence | denotes | Similar to cell lines, SSEA-4(+) primary prostate tumor cells also showed down-regulation of epithelial cell-associated markers. |
| T9 | 1135-1245 | Sentence | denotes | In addition, they showed up-regulation of epithelial-to-mesenchymal transition as well as mesenchymal markers. |
| T10 | 1246-1462 | Sentence | denotes | Furthermore, SSEA-4(+) cells escape from adhesive colonies spontaneously and form invadopodia-like migratory structures, in which SSEA-4, cortactin as well as active pPI3K, pAkt and pSrc are enriched and colocalized. |
| T11 | 1463-1642 | Sentence | denotes | Finally, SSEA-4(+) cells displayed strong tumorigenic ability and stable knockdown of SSEA-4 synthesis resulted in decreased cellular adhesion to different extracellular matrices. |
| T12 | 1643-1762 | Sentence | denotes | In conclusion, we introduce SSEA-4 as a novel marker to identify heterogeneous, invasive subpopulations of tumor cells. |
| T13 | 1763-2026 | Sentence | denotes | Moreover, increased cell-surface SSEA-4 expression is associated with the loss of cell-cell interactions and the gain of a migratory phenotype, suggesting an important role of SSEA-4 in cancer invasion by influencing cellular adhesion to the extracellular matrix. |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-134 | Sentence | denotes | Expression of stage-specific embryonic antigen-4 (SSEA-4) defines spontaneous loss of epithelial phenotype in human solid tumor cells. |
| T2 | 135-285 | Sentence | denotes | Stage-specific embryonic antigen-4 (SSEA-4) is a glycosphingolipid, which is overexpressed in some cancers and has been linked to disease progression. |
| T3 | 286-398 | Sentence | denotes | However, little is known about the functions of SSEA-4 and the characteristics of SSEA-4 expressing tumor cells. |
| T4 | 399-530 | Sentence | denotes | Our studies identified SSEA-4 expression on a subpopulation of cells in many solid tumor cell lines but not in leukemic cell lines. |
| T5 | 531-739 | Sentence | denotes | Fluorescence-activated cell sorting-sorted SSEA-4(+) prostate cancer cells formed fibroblast-like colonies with limited cell-cell contacts, whereas SSEA-4(-) cells formed cobblestone-like epithelial colonies. |
| T6 | 740-841 | Sentence | denotes | Only colonies derived from SSEA-4(+) cells were enriched for pluripotent embryonic stem cell markers. |
| T7 | 842-1005 | Sentence | denotes | Moreover, major epithelial cell-associated markers Claudin-7, E-cadherin, ESRP1 and GRHL2 were down-regulated in the SSEA-4(+) fraction of DU145 and HCT-116 cells. |
| T8 | 1006-1134 | Sentence | denotes | Similar to cell lines, SSEA-4(+) primary prostate tumor cells also showed down-regulation of epithelial cell-associated markers. |
| T9 | 1135-1245 | Sentence | denotes | In addition, they showed up-regulation of epithelial-to-mesenchymal transition as well as mesenchymal markers. |
| T10 | 1246-1462 | Sentence | denotes | Furthermore, SSEA-4(+) cells escape from adhesive colonies spontaneously and form invadopodia-like migratory structures, in which SSEA-4, cortactin as well as active pPI3K, pAkt and pSrc are enriched and colocalized. |
| T11 | 1463-1642 | Sentence | denotes | Finally, SSEA-4(+) cells displayed strong tumorigenic ability and stable knockdown of SSEA-4 synthesis resulted in decreased cellular adhesion to different extracellular matrices. |
| T12 | 1643-1762 | Sentence | denotes | In conclusion, we introduce SSEA-4 as a novel marker to identify heterogeneous, invasive subpopulations of tumor cells. |
| T13 | 1763-2026 | Sentence | denotes | Moreover, increased cell-surface SSEA-4 expression is associated with the loss of cell-cell interactions and the gain of a migratory phenotype, suggesting an important role of SSEA-4 in cancer invasion by influencing cellular adhesion to the extracellular matrix. |
GlyCosmos15-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 50-56 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-4 | http://www.glycoepitope.jp/epitopes/EP0044 |
| T2 | 171-177 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-4 | http://www.glycoepitope.jp/epitopes/EP0044 |
| T3 | 334-340 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-4 | http://www.glycoepitope.jp/epitopes/EP0044 |
| T4 | 368-374 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-4 | http://www.glycoepitope.jp/epitopes/EP0044 |
| T5 | 422-428 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-4 | http://www.glycoepitope.jp/epitopes/EP0044 |
| T6 | 574-580 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-4 | http://www.glycoepitope.jp/epitopes/EP0044 |
| T7 | 679-685 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-4 | http://www.glycoepitope.jp/epitopes/EP0044 |
| T8 | 767-773 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-4 | http://www.glycoepitope.jp/epitopes/EP0044 |
| T9 | 959-965 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-4 | http://www.glycoepitope.jp/epitopes/EP0044 |
| T10 | 1029-1035 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-4 | http://www.glycoepitope.jp/epitopes/EP0044 |
| T11 | 1259-1265 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-4 | http://www.glycoepitope.jp/epitopes/EP0044 |
| T12 | 1376-1382 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-4 | http://www.glycoepitope.jp/epitopes/EP0044 |
| T13 | 1472-1478 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-4 | http://www.glycoepitope.jp/epitopes/EP0044 |
| T14 | 1549-1555 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-4 | http://www.glycoepitope.jp/epitopes/EP0044 |
| T15 | 1671-1677 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-4 | http://www.glycoepitope.jp/epitopes/EP0044 |
| T16 | 1796-1802 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-4 | http://www.glycoepitope.jp/epitopes/EP0044 |
| T17 | 1939-1945 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-4 | http://www.glycoepitope.jp/epitopes/EP0044 |
GlyCosmos15-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 122-127 | Disease | denotes | tumor | MONDO:0005070 |
| T2 | 386-391 | Disease | denotes | tumor | MONDO:0005070 |
| T3 | 482-487 | Disease | denotes | tumor | MONDO:0005070 |
| T4 | 584-599 | Disease | denotes | prostate cancer | MONDO:0005159|MONDO:0008315 |
| T6 | 1047-1061 | Disease | denotes | prostate tumor | MONDO:0021259 |
| T7 | 1750-1755 | Disease | denotes | tumor | MONDO:0005070 |
| T8 | 1949-1955 | Disease | denotes | cancer | MONDO:0004992 |
GlyCosmos15-NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 110-115 | OrganismTaxon | denotes | human | 9606 |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 50-56 | Glycan | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84263XI |
| T2 | 171-177 | Glycan | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84263XI |
| T3 | 334-340 | Glycan | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84263XI |
| T4 | 368-374 | Glycan | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84263XI |
| T5 | 422-428 | Glycan | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84263XI |
| T6 | 574-580 | Glycan | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84263XI |
| T7 | 679-685 | Glycan | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84263XI |
| T8 | 767-773 | Glycan | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84263XI |
| T9 | 959-965 | Glycan | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84263XI |
| T10 | 1029-1035 | Glycan | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84263XI |
| T11 | 1259-1265 | Glycan | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84263XI |
| T12 | 1376-1382 | Glycan | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84263XI |
| T13 | 1472-1478 | Glycan | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84263XI |
| T14 | 1549-1555 | Glycan | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84263XI |
| T15 | 1671-1677 | Glycan | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84263XI |
| T16 | 1796-1802 | Glycan | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84263XI |
| T17 | 1939-1945 | Glycan | denotes | SSEA-4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84263XI |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 110-115 | OrganismTaxon | denotes | human | 9606 |
GlyCosmos-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 50-56 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-4 | http://www.glycoepitope.jp/epitopes/EP0044 |
| T2 | 171-177 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-4 | http://www.glycoepitope.jp/epitopes/EP0044 |
| T3 | 334-340 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-4 | http://www.glycoepitope.jp/epitopes/EP0044 |
| T4 | 368-374 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-4 | http://www.glycoepitope.jp/epitopes/EP0044 |
| T5 | 422-428 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-4 | http://www.glycoepitope.jp/epitopes/EP0044 |
| T6 | 574-580 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-4 | http://www.glycoepitope.jp/epitopes/EP0044 |
| T7 | 679-685 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-4 | http://www.glycoepitope.jp/epitopes/EP0044 |
| T8 | 767-773 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-4 | http://www.glycoepitope.jp/epitopes/EP0044 |
| T9 | 959-965 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-4 | http://www.glycoepitope.jp/epitopes/EP0044 |
| T10 | 1029-1035 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-4 | http://www.glycoepitope.jp/epitopes/EP0044 |
| T11 | 1259-1265 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-4 | http://www.glycoepitope.jp/epitopes/EP0044 |
| T12 | 1376-1382 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-4 | http://www.glycoepitope.jp/epitopes/EP0044 |
| T13 | 1472-1478 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-4 | http://www.glycoepitope.jp/epitopes/EP0044 |
| T14 | 1549-1555 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-4 | http://www.glycoepitope.jp/epitopes/EP0044 |
| T15 | 1671-1677 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-4 | http://www.glycoepitope.jp/epitopes/EP0044 |
| T16 | 1796-1802 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-4 | http://www.glycoepitope.jp/epitopes/EP0044 |
| T17 | 1939-1945 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | SSEA-4 | http://www.glycoepitope.jp/epitopes/EP0044 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 584-592 | Body_part | denotes | prostate | http://purl.obolibrary.org/obo/UBERON_0002367 |
| T2 | 613-623 | Body_part | denotes | fibroblast | http://purl.obolibrary.org/obo/CL_0000057 |
| T3 | 823-832 | Body_part | denotes | stem cell | http://purl.obolibrary.org/obo/CL_0000034 |
| T4 | 858-873 | Body_part | denotes | epithelial cell | http://purl.obolibrary.org/obo/CL_0000066 |
| T5 | 1047-1055 | Body_part | denotes | prostate | http://purl.obolibrary.org/obo/UBERON_0002367 |
| T6 | 1099-1114 | Body_part | denotes | epithelial cell | http://purl.obolibrary.org/obo/CL_0000066 |
| T7 | 1619-1632 | Body_part | denotes | extracellular | http://purl.obolibrary.org/obo/GO_0005576 |
| T8 | 2005-2025 | Body_part | denotes | extracellular matrix | http://purl.obolibrary.org/obo/GO_0031012 |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 584-592 | Body_part | denotes | prostate | http://purl.obolibrary.org/obo/MAT_0000078 |
| T2 | 823-832 | Body_part | denotes | stem cell | http://purl.obolibrary.org/obo/MAT_0000185 |
| T3 | 1047-1055 | Body_part | denotes | prostate | http://purl.obolibrary.org/obo/MAT_0000078 |
CL-cell
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 122-133 | Cell | denotes | tumor cells | http://purl.obolibrary.org/obo/CL:0001063 |
| T2 | 386-397 | Cell | denotes | tumor cells | http://purl.obolibrary.org/obo/CL:0001063 |
| T3 | 482-492 | Cell | denotes | tumor cell | http://purl.obolibrary.org/obo/CL:0001063 |
| T4 | 593-605 | Cell | denotes | cancer cells | http://purl.obolibrary.org/obo/CL:0001064 |
| T5 | 613-623 | Cell | denotes | fibroblast | http://purl.obolibrary.org/obo/CL:0000057 |
| T6 | 813-832 | Cell | denotes | embryonic stem cell | http://purl.obolibrary.org/obo/CL:0002322 |
| T7 | 823-832 | Cell | denotes | stem cell | http://purl.obolibrary.org/obo/CL:0000034 |
| T8 | 858-873 | Cell | denotes | epithelial cell | http://purl.obolibrary.org/obo/CL:0000066 |
| T9 | 1056-1067 | Cell | denotes | tumor cells | http://purl.obolibrary.org/obo/CL:0001063 |
| T10 | 1099-1114 | Cell | denotes | epithelial cell | http://purl.obolibrary.org/obo/CL:0000066 |
| T11 | 1750-1761 | Cell | denotes | tumor cells | http://purl.obolibrary.org/obo/CL:0001063 |