PubMed:2550128 JSONTXT

{"project":"sentences","denotations":[{"id":"TextSentencer_T1","span":{"begin":0,"end":138},"obj":"Sentence"},{"id":"TextSentencer_T2","span":{"begin":139,"end":458},"obj":"Sentence"},{"id":"TextSentencer_T3","span":{"begin":459,"end":686},"obj":"Sentence"},{"id":"T1","span":{"begin":0,"end":138},"obj":"Sentence"},{"id":"T2","span":{"begin":139,"end":458},"obj":"Sentence"},{"id":"T3","span":{"begin":459,"end":686},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"(1----3)-alpha-D-glucan from an alkaline extract of Agrocybe cylindracea, and antitumor activity of its O-(carboxymethyl)ated derivatives.\nThe structure of an alkali-soluble D-glucan (AG-AL) from the fruit body of Agrocybe cylindracea was investigated by a combination of chemical and spectroscopic methods indicating that it was a linear (1----3)-alpha-D-glucan (molecular weight, approximately 560,000), [alpha]20D +195 degrees (c 0.5, M sodium hydroxide). Both water-soluble and gelatinous products obtained by O-(carboxymethyl)ation of AG-AL showed potent antitumor activity against the solid form of Sarcoma 180 in mice, although the native D-glucan had little effect on the tumor."}

{"project":"PubmedHPO","denotations":[{"id":"T1","span":{"begin":605,"end":612},"obj":"HP_0100242"},{"id":"T2","span":{"begin":680,"end":685},"obj":"HP_0002664"}],"text":"(1----3)-alpha-D-glucan from an alkaline extract of Agrocybe cylindracea, and antitumor activity of its O-(carboxymethyl)ated derivatives.\nThe structure of an alkali-soluble D-glucan (AG-AL) from the fruit body of Agrocybe cylindracea was investigated by a combination of chemical and spectroscopic methods indicating that it was a linear (1----3)-alpha-D-glucan (molecular weight, approximately 560,000), [alpha]20D +195 degrees (c 0.5, M sodium hydroxide). Both water-soluble and gelatinous products obtained by O-(carboxymethyl)ation of AG-AL showed potent antitumor activity against the solid form of Sarcoma 180 in mice, although the native D-glucan had little effect on the tumor."}

{"project":"HP-phenotype","denotations":[{"id":"T1","span":{"begin":605,"end":612},"obj":"Phenotype"},{"id":"T2","span":{"begin":680,"end":685},"obj":"Phenotype"}],"attributes":[{"id":"A1","pred":"hp_id","subj":"T1","obj":"HP:0100242"},{"id":"A2","pred":"hp_id","subj":"T2","obj":"HP:0002664"}],"namespaces":[{"prefix":"HP","uri":"http://purl.obolibrary.org/obo/HP_"}],"text":"(1----3)-alpha-D-glucan from an alkaline extract of Agrocybe cylindracea, and antitumor activity of its O-(carboxymethyl)ated derivatives.\nThe structure of an alkali-soluble D-glucan (AG-AL) from the fruit body of Agrocybe cylindracea was investigated by a combination of chemical and spectroscopic methods indicating that it was a linear (1----3)-alpha-D-glucan (molecular weight, approximately 560,000), [alpha]20D +195 degrees (c 0.5, M sodium hydroxide). Both water-soluble and gelatinous products obtained by O-(carboxymethyl)ation of AG-AL showed potent antitumor activity against the solid form of Sarcoma 180 in mice, although the native D-glucan had little effect on the tumor."}

{"project":"mondo_disease","denotations":[{"id":"T1","span":{"begin":605,"end":612},"obj":"Disease"},{"id":"T2","span":{"begin":680,"end":685},"obj":"Disease"}],"attributes":[{"id":"A1","pred":"mondo_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/MONDO_0005089"},{"id":"A2","pred":"mondo_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/MONDO_0005070"}],"text":"(1----3)-alpha-D-glucan from an alkaline extract of Agrocybe cylindracea, and antitumor activity of its O-(carboxymethyl)ated derivatives.\nThe structure of an alkali-soluble D-glucan (AG-AL) from the fruit body of Agrocybe cylindracea was investigated by a combination of chemical and spectroscopic methods indicating that it was a linear (1----3)-alpha-D-glucan (molecular weight, approximately 560,000), [alpha]20D +195 degrees (c 0.5, M sodium hydroxide). Both water-soluble and gelatinous products obtained by O-(carboxymethyl)ation of AG-AL showed potent antitumor activity against the solid form of Sarcoma 180 in mice, although the native D-glucan had little effect on the tumor."}

{"project":"NCBITAXON","denotations":[{"id":"T1","span":{"begin":52,"end":72},"obj":"OrganismTaxon"},{"id":"T2","span":{"begin":214,"end":234},"obj":"OrganismTaxon"},{"id":"T3","span":{"begin":620,"end":624},"obj":"OrganismTaxon"}],"attributes":[{"id":"A1","pred":"db_id","subj":"T1","obj":"64608"},{"id":"A2","pred":"db_id","subj":"T2","obj":"64608"},{"id":"A3","pred":"db_id","subj":"T3","obj":"10088"}],"text":"(1----3)-alpha-D-glucan from an alkaline extract of Agrocybe cylindracea, and antitumor activity of its O-(carboxymethyl)ated derivatives.\nThe structure of an alkali-soluble D-glucan (AG-AL) from the fruit body of Agrocybe cylindracea was investigated by a combination of chemical and spectroscopic methods indicating that it was a linear (1----3)-alpha-D-glucan (molecular weight, approximately 560,000), [alpha]20D +195 degrees (c 0.5, M sodium hydroxide). Both water-soluble and gelatinous products obtained by O-(carboxymethyl)ation of AG-AL showed potent antitumor activity against the solid form of Sarcoma 180 in mice, although the native D-glucan had little effect on the tumor."}