PubMed:25286407 / 604-1121 JSONTXT

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    PubMed_Structured_Abstracts

    {"project":"PubMed_Structured_Abstracts","denotations":[{"id":"T2","span":{"begin":0,"end":517},"obj":"METHODS"}],"text":"For the organotypic culture model, rabbit IVDs were harvested and cultured for 3 or 7 days after intradiscal injection of local anesthetics (1% lidocaine or 0.5% bupivacaine). Nucleus pulposus (NP) cell death was measured using confocal microscopy. Histological and TUNEL assays were performed. For in vivo study, each local anesthetic was injected into rabbit lumbar IVDs under a fluoroscope. Six or 12 months after the injection, each IVD was prepared for magnetic resonance imaging (MRI) and histological analysis."}

    Goldhamster2_Cellosaurus

    {"project":"Goldhamster2_Cellosaurus","denotations":[{"id":"T7","span":{"begin":379,"end":380},"obj":"CVCL_6479|Finite_cell_line|Mus musculus"},{"id":"T8","span":{"begin":398,"end":403},"obj":"CVCL_S732|Cancer_cell_line|Homo sapiens"}],"text":"For the organotypic culture model, rabbit IVDs were harvested and cultured for 3 or 7 days after intradiscal injection of local anesthetics (1% lidocaine or 0.5% bupivacaine). Nucleus pulposus (NP) cell death was measured using confocal microscopy. Histological and TUNEL assays were performed. For in vivo study, each local anesthetic was injected into rabbit lumbar IVDs under a fluoroscope. Six or 12 months after the injection, each IVD was prepared for magnetic resonance imaging (MRI) and histological analysis."}

    GoldHamster

    {"project":"GoldHamster","denotations":[{"id":"T61","span":{"begin":35,"end":41},"obj":"813859"},{"id":"T60","span":{"begin":35,"end":41},"obj":"D011817"},{"id":"T62","span":{"begin":35,"end":41},"obj":"9986"},{"id":"T65","span":{"begin":122,"end":139},"obj":"CHEBI:36333"},{"id":"T66","span":{"begin":122,"end":139},"obj":"D000779"},{"id":"T67","span":{"begin":122,"end":139},"obj":"D000779"},{"id":"T71","span":{"begin":144,"end":153},"obj":"6387"},{"id":"T72","span":{"begin":144,"end":153},"obj":"D008012"},{"id":"T73","span":{"begin":144,"end":153},"obj":"CHEBI:6456"},{"id":"T74","span":{"begin":144,"end":153},"obj":"D008012"},{"id":"T76","span":{"begin":162,"end":173},"obj":"1815"},{"id":"T75","span":{"begin":162,"end":173},"obj":"D002045"},{"id":"T77","span":{"begin":162,"end":173},"obj":"CHEBI:3215"},{"id":"T78","span":{"begin":162,"end":173},"obj":"CHEBI:60790"},{"id":"T79","span":{"begin":162,"end":173},"obj":"CHEBI:6149"},{"id":"T80","span":{"begin":162,"end":173},"obj":"D002045"},{"id":"T83","span":{"begin":176,"end":183},"obj":"GO:0005634"},{"id":"T81","span":{"begin":176,"end":183},"obj":"CHEBI:33252"},{"id":"T84","span":{"begin":176,"end":192},"obj":"UBERON:0002242"},{"id":"T85","span":{"begin":198,"end":208},"obj":"GO:0008219"},{"id":"T87","span":{"begin":354,"end":360},"obj":"813859"},{"id":"T86","span":{"begin":354,"end":360},"obj":"D011817"},{"id":"T88","span":{"begin":354,"end":360},"obj":"9986"},{"id":"T89","span":{"begin":437,"end":440},"obj":"Q9FS87"},{"id":"T90","span":{"begin":437,"end":440},"obj":"Q9SWG0"},{"id":"T91","span":{"begin":437,"end":440},"obj":"P12007"},{"id":"T92","span":{"begin":437,"end":440},"obj":"P26440"},{"id":"T93","span":{"begin":437,"end":440},"obj":"Q3SZI8"},{"id":"T94","span":{"begin":437,"end":440},"obj":"PR:P12007"},{"id":"T95","span":{"begin":437,"end":440},"obj":"P34275"},{"id":"T96","span":{"begin":437,"end":440},"obj":"Q9JHI5"},{"id":"T97","span":{"begin":437,"end":440},"obj":"PR:Q9SWG0"},{"id":"T98","span":{"begin":437,"end":440},"obj":"Q75IM9"},{"id":"T99","span":{"begin":437,"end":440},"obj":"PR:P26440"},{"id":"T100","span":{"begin":437,"end":440},"obj":"Q5RBD5"},{"id":"T101","span":{"begin":437,"end":440},"obj":"PR:000009166"},{"id":"T102","span":{"begin":437,"end":440},"obj":"PR:Q9JHI5"},{"id":"T103","span":{"begin":486,"end":489},"obj":"PR:000010565"},{"id":"T104","span":{"begin":486,"end":489},"obj":"PR:Q6AYH4"},{"id":"T105","span":{"begin":486,"end":489},"obj":"PR:Q8BHZ5"},{"id":"T106","span":{"begin":486,"end":489},"obj":"PR:Q9BWK5"}],"text":"For the organotypic culture model, rabbit IVDs were harvested and cultured for 3 or 7 days after intradiscal injection of local anesthetics (1% lidocaine or 0.5% bupivacaine). Nucleus pulposus (NP) cell death was measured using confocal microscopy. Histological and TUNEL assays were performed. For in vivo study, each local anesthetic was injected into rabbit lumbar IVDs under a fluoroscope. Six or 12 months after the injection, each IVD was prepared for magnetic resonance imaging (MRI) and histological analysis."}