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PubMed:25156158 JSONTXT

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PubMed_ArguminSci

Id Subject Object Predicate Lexical cue
T1 107-122 DRI_Approach denotes The Frog Embryo
T2 151-222 DRI_Approach denotes (FETAX) was used to assess the teratogenic potential of two tocolytics.
T3 223-321 DRI_Background denotes Embryos of the South African clawed frog, Xenopus laevis, were exposed to ritodrine or nifedipine.
T4 322-385 DRI_Background denotes Exposure media were changed and monitored at 24-hour intervals.
T5 653-839 DRI_Outcome denotes Nifedipine was determined to be the more toxic and teratogenic than ritodrine, with a LC50 of 0.606 µg/L, an EC50 of 0.006 µg/L, and a teratogenicity Index (TI) value (LC50/EC50) of 101.
T6 840-897 DRI_Outcome denotes On the other hand, the LC50 of ritodrine was 28.571 mg/L.
T7 898-1073 DRI_Background denotes In addition; the LC50, EC50 and TI values for nifedipine in the 5 mg/L ritodrine + nifedipine combination group were determined as 1.050 µg/L, 0.868 µg/L and 1.5 respectively.
T8 1074-1167 DRI_Approach denotes For ritodrine, the NOAEC and LOAEC values were determined as 2 mg/L and 4 mg/L, respectively.
T9 1168-1309 DRI_Background denotes For the nifedipine and the ritodrine + nifedipine groups; while the LOAEC values of these groups were 0.0001 µg/L and 0.1 µg/L, respectively.
T10 1310-1345 DRI_Approach denotes NOAEC value couldn't be determined.
T11 1346-1469 DRI_Outcome denotes Our results demonstrated that nifedipine administration was associated with higher levels of teratogenic and toxic effects.
T12 1470-1598 DRI_Background denotes However, the ritodrine + nifedipine combination form reduced the toxic and teratogenic effects of nifedipine on Xenopus embryos.
T13 1599-1753 DRI_Approach denotes Further studies should be conducted in order to investigate the optimal combination concentrations of these substances for the treatment of preterm labor.

Goldhamster2_Cellosaurus

Id Subject Object Predicate Lexical cue
T1 64-65 CVCL_6479|Finite_cell_line|Mus musculus denotes a
T2 66-70 CVCL_0C97|Cancer_cell_line|Canis lupus familiaris denotes Frog
T3 111-115 CVCL_0C97|Cancer_cell_line|Canis lupus familiaris denotes Frog
T4 259-263 CVCL_0C97|Cancer_cell_line|Canis lupus familiaris denotes frog
T5 342-349 CVCL_0238|Cancer_cell_line|Homo sapiens denotes changed
T6 439-443 CVCL_IR37|Cancer_cell_line|Homo sapiens denotes EC50
T7 737-738 CVCL_6479|Finite_cell_line|Mus musculus denotes a
T8 759-761 CVCL_8754|Cancer_cell_line|Homo sapiens denotes an
T9 759-761 CVCL_H241|Cancer_cell_line|Homo sapiens denotes an
T10 762-766 CVCL_IR37|Cancer_cell_line|Homo sapiens denotes EC50
T11 786-787 CVCL_6479|Finite_cell_line|Mus musculus denotes a
T12 826-830 CVCL_IR37|Cancer_cell_line|Homo sapiens denotes EC50
T13 921-925 CVCL_IR37|Cancer_cell_line|Homo sapiens denotes EC50
T14 1132-1136 CVCL_XH98|Hybridoma|Mus musculus denotes as 2
T15 1142-1147 CVCL_K225|Induced_pluripotent_stem_cell|Homo sapiens denotes and 4

GoldHamster

Id Subject Object Predicate Lexical cue
T1 33-42 D012312 denotes Ritodrine
T2 33-42 D012312 denotes Ritodrine
T3 33-42 CHEBI:8872 denotes Ritodrine
T4 47-57 7417 denotes Nifedipine
T5 47-57 D009543 denotes Nifedipine
T6 47-57 CHEBI:7565 denotes Nifedipine
T7 47-57 D009543 denotes Nifedipine
T8 66-70 CVCL_0C97 denotes Frog
T9 71-77 UBERON:0000922 denotes Embryo
T10 78-91 D064793 denotes Teratogenesis
T11 78-91 D064793 denotes Teratogenesis
T12 111-115 CVCL_0C97 denotes Frog
T13 116-122 UBERON:0000922 denotes Embryo
T14 123-136 D064793 denotes Teratogenesis
T15 123-136 D064793 denotes Teratogenesis
T16 143-150 451443 denotes Xenopus
T17 143-150 451444 denotes Xenopus
T18 143-150 288623 denotes Xenopus
T19 143-150 1589957 denotes Xenopus
T20 143-150 8364 denotes Xenopus
T21 143-150 D014981 denotes Xenopus
T22 143-150 698687 denotes Xenopus
T23 143-150 224340 denotes Xenopus
T118 1483-1492 D012312 denotes ritodrine
T119 1483-1492 D012312 denotes ritodrine
T24 211-221 D015149 denotes tocolytics
T25 211-221 D015149 denotes tocolytics
T26 211-221 CHEBI:66993 denotes tocolytics
T27 244-263 8355 denotes African clawed frog
T30 252-279 8355 denotes clawed frog, Xenopus laevis
T31 259-263 CVCL_0C97 denotes frog
T42 297-306 D012312 denotes ritodrine
T43 297-306 D012312 denotes ritodrine
T44 297-306 CHEBI:8872 denotes ritodrine
T45 310-320 7417 denotes nifedipine
T46 310-320 D009543 denotes nifedipine
T47 310-320 CHEBI:7565 denotes nifedipine
T48 310-320 D009543 denotes nifedipine
T50 439-443 CVCL_IR37 denotes EC50
T51 647-651 CHEBI:23888 denotes drug
T52 653-663 7417 denotes Nifedipine
T53 653-663 D009543 denotes Nifedipine
T54 653-663 CHEBI:7565 denotes Nifedipine
T55 653-663 D009543 denotes Nifedipine
T56 721-730 D012312 denotes ritodrine
T57 721-730 D012312 denotes ritodrine
T58 721-730 CHEBI:8872 denotes ritodrine
T59 762-766 CVCL_IR37 denotes EC50
T60 826-830 CVCL_IR37 denotes EC50
T61 871-880 D012312 denotes ritodrine
T62 871-880 D012312 denotes ritodrine
T63 871-880 CHEBI:8872 denotes ritodrine
T64 921-925 CVCL_IR37 denotes EC50
T65 944-954 7417 denotes nifedipine
T66 944-954 D009543 denotes nifedipine
T67 944-954 CHEBI:7565 denotes nifedipine
T68 944-954 D009543 denotes nifedipine
T69 969-978 D012312 denotes ritodrine
T70 969-978 D012312 denotes ritodrine
T71 969-978 CHEBI:8872 denotes ritodrine
T72 981-991 7417 denotes nifedipine
T73 981-991 D009543 denotes nifedipine
T74 981-991 CHEBI:7565 denotes nifedipine
T75 981-991 D009543 denotes nifedipine
T90 1078-1087 D012312 denotes ritodrine
T91 1078-1087 D012312 denotes ritodrine
T92 1078-1087 CHEBI:8872 denotes ritodrine
T103 1176-1186 7417 denotes nifedipine
T104 1176-1186 D009543 denotes nifedipine
T105 1176-1186 CHEBI:7565 denotes nifedipine
T106 1176-1186 D009543 denotes nifedipine
T107 1195-1204 D012312 denotes ritodrine
T108 1195-1204 D012312 denotes ritodrine
T109 1195-1204 CHEBI:8872 denotes ritodrine
T110 1207-1217 7417 denotes nifedipine
T111 1207-1217 D009543 denotes nifedipine
T112 1207-1217 CHEBI:7565 denotes nifedipine
T113 1207-1217 D009543 denotes nifedipine
T114 1376-1386 7417 denotes nifedipine
T115 1376-1386 D009543 denotes nifedipine
T116 1376-1386 CHEBI:7565 denotes nifedipine
T117 1376-1386 D009543 denotes nifedipine
T120 1483-1492 CHEBI:8872 denotes ritodrine
T121 1495-1505 7417 denotes nifedipine
T122 1495-1505 D009543 denotes nifedipine
T123 1495-1505 CHEBI:7565 denotes nifedipine
T124 1495-1505 D009543 denotes nifedipine
T125 1568-1578 7417 denotes nifedipine
T126 1568-1578 D009543 denotes nifedipine
T127 1568-1578 CHEBI:7565 denotes nifedipine
T128 1568-1578 D009543 denotes nifedipine
T129 1582-1589 451443 denotes Xenopus
T130 1582-1589 451444 denotes Xenopus
T131 1582-1589 288623 denotes Xenopus
T132 1582-1589 1589957 denotes Xenopus
T133 1582-1589 8364 denotes Xenopus
T134 1582-1589 D014981 denotes Xenopus
T135 1582-1589 698687 denotes Xenopus
T136 1582-1589 224340 denotes Xenopus
T137 1739-1752 D007752 denotes preterm labor
T138 1739-1752 D007752 denotes preterm labor