PubMed:25040827 JSONTXT

{"project":"silkwormbase","denotations":[{"id":"T1","span":{"begin":31,"end":39},"obj":"Chemical:-"},{"id":"T10","span":{"begin":519,"end":523},"obj":"Gene:692767"},{"id":"T11","span":{"begin":532,"end":547},"obj":"Disease:MESH:D018981"},{"id":"T12","span":{"begin":563,"end":579},"obj":"Species:562"},{"id":"T2","span":{"begin":63,"end":89},"obj":"Gene:692767"},{"id":"T3","span":{"begin":108,"end":119},"obj":"Species:7091"},{"id":"T4","span":{"begin":154,"end":162},"obj":"Chemical:-"},{"id":"T5","span":{"begin":170,"end":196},"obj":"Gene:692767"},{"id":"T6","span":{"begin":198,"end":202},"obj":"Gene:692767"},{"id":"T7","span":{"begin":388,"end":392},"obj":"Gene:692767"},{"id":"T8","span":{"begin":441,"end":442},"obj":"Chemical:MESH:D009584"},{"id":"T9","span":{"begin":456,"end":460},"obj":"Gene:692767"},{"id":"T16","span":{"begin":63,"end":89},"obj":"BMO_00114"},{"id":"T20","span":{"begin":170,"end":196},"obj":"BMO_00114"},{"id":"T21","span":{"begin":198,"end":202},"obj":"BMO_00114"},{"id":"T23","span":{"begin":388,"end":392},"obj":"BMO_00114"},{"id":"T24","span":{"begin":456,"end":460},"obj":"BMO_00114"},{"id":"T25","span":{"begin":519,"end":523},"obj":"BMO_00114"}],"text":"Structural determination of an N-glycan moiety attached to the prothoracicotropic hormone from the silkmoth Bombyx mori.\nThe predominant structure of the N-glycan on the prothoracicotropic hormone (PTTH) isolated from 1.8 million adult heads of silkmoths was determined to be Manα1-6Manβ1-4GlcNAcβ1-4(Fucα1-6)GlcNAc-OH, which is identical to that of the baculovirus-expressed recombinant PTTH. An ecdysis progression assay demonstrated that N-glycosylated PTTH exhibited a slightly higher activity than the recombinant PTTH without N-glycosylation produced by an Escherichia coli expression system."}

{"project":"silkworm_phenotype","denotations":[{"id":"T25","span":{"begin":519,"end":523},"obj":"BMO_00114"},{"id":"T24","span":{"begin":456,"end":460},"obj":"BMO_00114"},{"id":"T23","span":{"begin":388,"end":392},"obj":"BMO_00114"},{"id":"T21","span":{"begin":198,"end":202},"obj":"BMO_00114"},{"id":"T20","span":{"begin":170,"end":196},"obj":"BMO_00114"},{"id":"T16","span":{"begin":63,"end":89},"obj":"BMO_00114"},{"id":"T9","span":{"begin":456,"end":460},"obj":"Gene:692767"},{"id":"T8","span":{"begin":441,"end":442},"obj":"Chemical:MESH:D009584"},{"id":"T7","span":{"begin":388,"end":392},"obj":"Gene:692767"},{"id":"T6","span":{"begin":198,"end":202},"obj":"Gene:692767"},{"id":"T5","span":{"begin":170,"end":196},"obj":"Gene:692767"},{"id":"T4","span":{"begin":154,"end":162},"obj":"Chemical:-"},{"id":"T3","span":{"begin":108,"end":119},"obj":"Species:7091"},{"id":"T2","span":{"begin":63,"end":89},"obj":"Gene:692767"},{"id":"T12","span":{"begin":563,"end":579},"obj":"Species:562"},{"id":"T11","span":{"begin":532,"end":547},"obj":"Disease:MESH:D018981"},{"id":"T10","span":{"begin":519,"end":523},"obj":"Gene:692767"},{"id":"T1","span":{"begin":31,"end":39},"obj":"Chemical:-"}],"text":"Structural determination of an N-glycan moiety attached to the prothoracicotropic hormone from the silkmoth Bombyx mori.\nThe predominant structure of the N-glycan on the prothoracicotropic hormone (PTTH) isolated from 1.8 million adult heads of silkmoths was determined to be Manα1-6Manβ1-4GlcNAcβ1-4(Fucα1-6)GlcNAc-OH, which is identical to that of the baculovirus-expressed recombinant PTTH. An ecdysis progression assay demonstrated that N-glycosylated PTTH exhibited a slightly higher activity than the recombinant PTTH without N-glycosylation produced by an Escherichia coli expression system."}

{"project":"silkworm","denotations":[{"id":"T1","span":{"begin":31,"end":39},"obj":"Chemical:-"},{"id":"T2","span":{"begin":63,"end":89},"obj":"Gene:692767"},{"id":"T3","span":{"begin":108,"end":119},"obj":"Species:7091"},{"id":"T4","span":{"begin":154,"end":162},"obj":"Chemical:-"},{"id":"T5","span":{"begin":170,"end":196},"obj":"Gene:692767"},{"id":"T6","span":{"begin":198,"end":202},"obj":"Gene:692767"},{"id":"T7","span":{"begin":388,"end":392},"obj":"Gene:692767"},{"id":"T8","span":{"begin":441,"end":442},"obj":"Chemical:MESH:D009584"},{"id":"T9","span":{"begin":456,"end":460},"obj":"Gene:692767"},{"id":"T10","span":{"begin":519,"end":523},"obj":"Gene:692767"},{"id":"T11","span":{"begin":532,"end":547},"obj":"Disease:MESH:D018981"},{"id":"T12","span":{"begin":563,"end":579},"obj":"Species:562"}],"text":"Structural determination of an N-glycan moiety attached to the prothoracicotropic hormone from the silkmoth Bombyx mori.\nThe predominant structure of the N-glycan on the prothoracicotropic hormone (PTTH) isolated from 1.8 million adult heads of silkmoths was determined to be Manα1-6Manβ1-4GlcNAcβ1-4(Fucα1-6)GlcNAc-OH, which is identical to that of the baculovirus-expressed recombinant PTTH. An ecdysis progression assay demonstrated that N-glycosylated PTTH exhibited a slightly higher activity than the recombinant PTTH without N-glycosylation produced by an Escherichia coli expression system."}

{"project":"Allie","denotations":[{"id":"SS1_25040827_1_0","span":{"begin":170,"end":196},"obj":"expanded"},{"id":"SS2_25040827_1_0","span":{"begin":198,"end":202},"obj":"abbr"}],"relations":[{"id":"AE1_25040827_1_0","pred":"abbreviatedTo","subj":"SS1_25040827_1_0","obj":"SS2_25040827_1_0"}],"text":"Structural determination of an N-glycan moiety attached to the prothoracicotropic hormone from the silkmoth Bombyx mori.\nThe predominant structure of the N-glycan on the prothoracicotropic hormone (PTTH) isolated from 1.8 million adult heads of silkmoths was determined to be Manα1-6Manβ1-4GlcNAcβ1-4(Fucα1-6)GlcNAc-OH, which is identical to that of the baculovirus-expressed recombinant PTTH. An ecdysis progression assay demonstrated that N-glycosylated PTTH exhibited a slightly higher activity than the recombinant PTTH without N-glycosylation produced by an Escherichia coli expression system."}

{"project":"NGLY1-deficiency","denotations":[{"id":"PD-NGLY1-deficiency-B_T1","span":{"begin":309,"end":315},"obj":"chem:24139"}],"namespaces":[{"prefix":"hgnc","uri":"https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:"},{"prefix":"omim","uri":"https://www.omim.org/entry/"},{"prefix":"chem","uri":"https://pubchem.ncbi.nlm.nih.gov/compound/"}],"text":"Structural determination of an N-glycan moiety attached to the prothoracicotropic hormone from the silkmoth Bombyx mori.\nThe predominant structure of the N-glycan on the prothoracicotropic hormone (PTTH) isolated from 1.8 million adult heads of silkmoths was determined to be Manα1-6Manβ1-4GlcNAcβ1-4(Fucα1-6)GlcNAc-OH, which is identical to that of the baculovirus-expressed recombinant PTTH. An ecdysis progression assay demonstrated that N-glycosylated PTTH exhibited a slightly higher activity than the recombinant PTTH without N-glycosylation produced by an Escherichia coli expression system."}