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LitCoin-sentences

Id Subject Object Predicate Lexical cue
T1 0-84 Sentence denotes IL-3 and CSF-1 interact to promote generation of CD11c+ IL-10-producing macrophages.
T2 85-194 Sentence denotes Unraveling the mechanisms of hematopoiesis regulated by multiple cytokines remains a challenge in hematology.
T3 195-334 Sentence denotes IL-3 is an allergic cytokine with the multilineage potential, while CSF-1 is produced in the steady state with restricted lineage coverage.
T4 335-414 Sentence denotes Here, we uncovered an instructive role of CSF-1 in IL-3-mediated hematopoiesis.
T5 415-550 Sentence denotes CSF-1 significantly promoted IL-3-driven CD11c+ cell expansion and dampened basophil and mast cell generation from C57BL/6 bone marrow.
T6 551-716 Sentence denotes Further studies indicated that the CSF-1/CSF-1R axis contributed significantly to IL-3-induced CD11c+ cell generation through enhancing c-Fos-associated monopoiesis.
T7 717-814 Sentence denotes CD11c+ cells induced by IL-3 or IL-3/CSF-1 were competent in cellular maturation and endocytosis.
T8 815-929 Sentence denotes Both IL-3 and IL-3/CSF-1 cells lacked classical dendritic cell appearance and resembled macrophages in morphology.
T9 930-1079 Sentence denotes Both populations produced a high level of IL-10, in addition to IL-1, IL-6 and TNFα, in response to LPS, and were relatively poor T cell stimulators.
T10 1080-1246 Sentence denotes Collectively, these findings reveal a role for CSF-1 in mediating the IL-3 hematopoietic pathway through monopoiesis, which regulates expansion of CD11c+ macrophages.

LitCoin-entities

Id Subject Object Predicate Lexical cue db_id
9894 0-4 GeneOrGeneProduct denotes IL-3 NCBIGene:16187
9895 9-14 GeneOrGeneProduct denotes CSF-1 NCBIGene:12977
9896 49-54 GeneOrGeneProduct denotes CD11c NCBIGene:16411
9897 56-61 GeneOrGeneProduct denotes IL-10 NCBIGene:16153
9898 195-199 GeneOrGeneProduct denotes IL-3 NCBIGene:16187
9899 263-268 GeneOrGeneProduct denotes CSF-1 NCBIGene:12977
9900 377-382 GeneOrGeneProduct denotes CSF-1 NCBIGene:12977
9901 386-390 GeneOrGeneProduct denotes IL-3 NCBIGene:16187
9902 415-420 GeneOrGeneProduct denotes CSF-1 NCBIGene:12977
9903 444-448 GeneOrGeneProduct denotes IL-3 NCBIGene:16187
9904 456-461 GeneOrGeneProduct denotes CD11c NCBIGene:16411
9905 530-537 CellLine denotes C57BL/6 NCBITaxon:10090
9906 586-591 GeneOrGeneProduct denotes CSF-1 NCBIGene:12977
9907 592-598 GeneOrGeneProduct denotes CSF-1R NCBIGene:12978
9908 633-637 GeneOrGeneProduct denotes IL-3 NCBIGene:16187
9909 646-651 GeneOrGeneProduct denotes CD11c NCBIGene:16411
9910 687-692 GeneOrGeneProduct denotes c-Fos NCBIGene:14281
9911 717-722 GeneOrGeneProduct denotes CD11c NCBIGene:16411
9912 741-745 GeneOrGeneProduct denotes IL-3 NCBIGene:16187
9913 749-753 GeneOrGeneProduct denotes IL-3 NCBIGene:16187
9914 754-759 GeneOrGeneProduct denotes CSF-1 NCBIGene:12977
9915 820-824 GeneOrGeneProduct denotes IL-3 NCBIGene:16187
9916 829-833 GeneOrGeneProduct denotes IL-3 NCBIGene:16187
9917 834-839 GeneOrGeneProduct denotes CSF-1 NCBIGene:12977
9918 972-977 GeneOrGeneProduct denotes IL-10 NCBIGene:16153
9919 994-998 GeneOrGeneProduct denotes IL-1 NCBIGene:111343
9920 1000-1004 GeneOrGeneProduct denotes IL-6 NCBIGene:16193
9921 1009-1013 GeneOrGeneProduct denotes TNFα NCBIGene:21926
9922 1030-1033 ChemicalEntity denotes LPS MESH:D008070
9923 1127-1132 GeneOrGeneProduct denotes CSF-1 NCBIGene:12977
9924 1150-1154 GeneOrGeneProduct denotes IL-3 NCBIGene:16187
9925 1227-1232 GeneOrGeneProduct denotes CD11c NCBIGene:16411

LitCoin-GeneOrGeneProduct-v2

Id Subject Object Predicate Lexical cue
T1 0-4 GeneOrGeneProduct denotes IL-3
T2 9-14 GeneOrGeneProduct denotes CSF-1
T3 49-54 GeneOrGeneProduct denotes CD11c
T4 56-61 GeneOrGeneProduct denotes IL-10
T5 141-149 GeneOrGeneProduct denotes multiple
T6 195-199 GeneOrGeneProduct denotes IL-3
T7 263-268 GeneOrGeneProduct denotes CSF-1
T8 344-353 GeneOrGeneProduct denotes uncovered
T9 377-382 GeneOrGeneProduct denotes CSF-1
T10 386-390 GeneOrGeneProduct denotes IL-3
T11 415-420 GeneOrGeneProduct denotes CSF-1
T12 444-448 GeneOrGeneProduct denotes IL-3
T13 456-461 GeneOrGeneProduct denotes CD11c
T14 463-467 GeneOrGeneProduct denotes cell
T15 468-477 GeneOrGeneProduct denotes expansion
T16 482-490 GeneOrGeneProduct denotes dampened
T17 504-508 GeneOrGeneProduct denotes mast
T18 509-513 GeneOrGeneProduct denotes cell
T19 586-591 GeneOrGeneProduct denotes CSF-1
T20 592-598 GeneOrGeneProduct denotes CSF-1R
T21 599-603 GeneOrGeneProduct denotes axis
T22 633-637 GeneOrGeneProduct denotes IL-3
T23 646-651 GeneOrGeneProduct denotes CD11c
T24 653-657 GeneOrGeneProduct denotes cell
T25 687-692 GeneOrGeneProduct denotes c-Fos
T26 717-722 GeneOrGeneProduct denotes CD11c
T27 741-745 GeneOrGeneProduct denotes IL-3
T28 749-753 GeneOrGeneProduct denotes IL-3
T29 754-759 GeneOrGeneProduct denotes CSF-1
T30 787-797 GeneOrGeneProduct denotes maturation
T31 820-824 GeneOrGeneProduct denotes IL-3
T32 829-833 GeneOrGeneProduct denotes IL-3
T33 834-839 GeneOrGeneProduct denotes CSF-1
T34 873-877 GeneOrGeneProduct denotes cell
T35 958-962 GeneOrGeneProduct denotes high
T36 972-977 GeneOrGeneProduct denotes IL-10
T37 994-998 GeneOrGeneProduct denotes IL-1
T38 1000-1004 GeneOrGeneProduct denotes IL-6
T39 1062-1066 GeneOrGeneProduct denotes cell
T40 1127-1132 GeneOrGeneProduct denotes CSF-1
T41 1150-1154 GeneOrGeneProduct denotes IL-3
T42 1214-1223 GeneOrGeneProduct denotes expansion
T43 1227-1232 GeneOrGeneProduct denotes CD11c

LitCoin-GeneOrGeneProduct-v0

Id Subject Object Predicate Lexical cue
T1 0-4 GeneOrGeneProduct denotes IL-3
T2 9-14 GeneOrGeneProduct denotes CSF-1
T3 49-54 GeneOrGeneProduct denotes CD11c
T4 56-61 GeneOrGeneProduct denotes IL-10
T5 128-137 GeneOrGeneProduct denotes regulated
T6 141-149 GeneOrGeneProduct denotes multiple
T7 195-199 GeneOrGeneProduct denotes IL-3
T8 263-268 GeneOrGeneProduct denotes CSF-1
T9 344-353 GeneOrGeneProduct denotes uncovered
T10 377-382 GeneOrGeneProduct denotes CSF-1
T11 386-390 GeneOrGeneProduct denotes IL-3
T12 391-399 GeneOrGeneProduct denotes mediated
T13 415-420 GeneOrGeneProduct denotes CSF-1
T14 444-448 GeneOrGeneProduct denotes IL-3
T15 456-461 GeneOrGeneProduct denotes CD11c
T16 463-467 GeneOrGeneProduct denotes cell
T17 468-477 GeneOrGeneProduct denotes expansion
T18 482-490 GeneOrGeneProduct denotes dampened
T19 491-499 GeneOrGeneProduct denotes basophil
T20 504-508 GeneOrGeneProduct denotes mast
T21 509-513 GeneOrGeneProduct denotes cell
T22 538-542 GeneOrGeneProduct denotes bone
T23 586-591 GeneOrGeneProduct denotes CSF-1
T24 592-598 GeneOrGeneProduct denotes CSF-1R
T25 599-603 GeneOrGeneProduct denotes axis
T26 633-637 GeneOrGeneProduct denotes IL-3
T27 638-645 GeneOrGeneProduct denotes induced
T28 646-651 GeneOrGeneProduct denotes CD11c
T29 653-657 GeneOrGeneProduct denotes cell
T30 687-692 GeneOrGeneProduct denotes c-Fos
T31 717-722 GeneOrGeneProduct denotes CD11c
T32 724-729 GeneOrGeneProduct denotes cells
T33 730-737 GeneOrGeneProduct denotes induced
T34 741-745 GeneOrGeneProduct denotes IL-3
T35 749-753 GeneOrGeneProduct denotes IL-3
T36 754-759 GeneOrGeneProduct denotes CSF-1
T37 787-797 GeneOrGeneProduct denotes maturation
T38 820-824 GeneOrGeneProduct denotes IL-3
T39 829-833 GeneOrGeneProduct denotes IL-3
T40 834-839 GeneOrGeneProduct denotes CSF-1
T41 840-845 GeneOrGeneProduct denotes cells
T42 846-852 GeneOrGeneProduct denotes lacked
T43 873-877 GeneOrGeneProduct denotes cell
T44 958-962 GeneOrGeneProduct denotes high
T45 972-977 GeneOrGeneProduct denotes IL-10
T46 994-998 GeneOrGeneProduct denotes IL-1
T47 1000-1004 GeneOrGeneProduct denotes IL-6
T48 1062-1066 GeneOrGeneProduct denotes cell
T49 1100-1108 GeneOrGeneProduct denotes findings
T50 1127-1132 GeneOrGeneProduct denotes CSF-1
T51 1136-1145 GeneOrGeneProduct denotes mediating
T52 1150-1154 GeneOrGeneProduct denotes IL-3
T53 1204-1213 GeneOrGeneProduct denotes regulates
T54 1214-1223 GeneOrGeneProduct denotes expansion
T55 1227-1232 GeneOrGeneProduct denotes CD11c

LitCoin-GeneOrGeneProduct-v3

Id Subject Object Predicate Lexical cue
T1 0-4 GeneOrGeneProduct denotes IL-3
T2 9-14 GeneOrGeneProduct denotes CSF-1
T3 49-54 GeneOrGeneProduct denotes CD11c
T4 56-61 GeneOrGeneProduct denotes IL-10
T5 195-199 GeneOrGeneProduct denotes IL-3
T6 263-268 GeneOrGeneProduct denotes CSF-1
T7 344-353 GeneOrGeneProduct denotes uncovered
T8 377-382 GeneOrGeneProduct denotes CSF-1
T9 386-390 GeneOrGeneProduct denotes IL-3
T10 415-420 GeneOrGeneProduct denotes CSF-1
T11 444-448 GeneOrGeneProduct denotes IL-3
T12 456-461 GeneOrGeneProduct denotes CD11c
T13 468-477 GeneOrGeneProduct denotes expansion
T14 482-490 GeneOrGeneProduct denotes dampened
T15 504-508 GeneOrGeneProduct denotes mast
T16 586-591 GeneOrGeneProduct denotes CSF-1
T17 592-598 GeneOrGeneProduct denotes CSF-1R
T18 633-637 GeneOrGeneProduct denotes IL-3
T19 646-651 GeneOrGeneProduct denotes CD11c
T20 687-692 GeneOrGeneProduct denotes c-Fos
T21 717-722 GeneOrGeneProduct denotes CD11c
T22 741-745 GeneOrGeneProduct denotes IL-3
T23 749-753 GeneOrGeneProduct denotes IL-3
T24 754-759 GeneOrGeneProduct denotes CSF-1
T25 820-824 GeneOrGeneProduct denotes IL-3
T26 829-833 GeneOrGeneProduct denotes IL-3
T27 834-839 GeneOrGeneProduct denotes CSF-1
T28 972-977 GeneOrGeneProduct denotes IL-10
T29 994-998 GeneOrGeneProduct denotes IL-1
T30 1000-1004 GeneOrGeneProduct denotes IL-6
T31 1127-1132 GeneOrGeneProduct denotes CSF-1
T32 1150-1154 GeneOrGeneProduct denotes IL-3
T33 1214-1223 GeneOrGeneProduct denotes expansion
T34 1227-1232 GeneOrGeneProduct denotes CD11c

LitCoin_Mondo_095

Id Subject Object Predicate Lexical cue mondo_id
T1 206-214 DiseaseOrPhenotypicFeature denotes allergic 0004980
T2 1030-1033 DiseaseOrPhenotypicFeature denotes LPS 0019508

LitCoin_CellLine

Id Subject Object Predicate Lexical cue cellosaurus_accession_id
T1 530-537 CellLine denotes C57BL/6 AddedByYayamamo

LitCoin-Chemical-MeSH-CHEBI

Id Subject Object Predicate Lexical cue ID:
T1 1030-1033 ChemicalEntity denotes LPS http://purl.obolibrary.org/obo/CHEBI_89981|http://purl.obolibrary.org/obo/CHEBI_52603|http://purl.obolibrary.org/obo/CHEBI_16412

LitCoin-training-merged

Id Subject Object Predicate Lexical cue ID: cellosaurus_accession_id
T1 530-537 CellLine denotes C57BL/6 AddedByYayamamo
T11851 1030-1033 ChemicalEntity denotes LPS http://purl.obolibrary.org/obo/CHEBI_16412|http://purl.obolibrary.org/obo/CHEBI_52603|http://purl.obolibrary.org/obo/CHEBI_89981
T34 1227-1232 GeneOrGeneProduct denotes CD11c
T33 1214-1223 GeneOrGeneProduct denotes expansion
T32 1150-1154 GeneOrGeneProduct denotes IL-3
T31 1127-1132 GeneOrGeneProduct denotes CSF-1
T30 1000-1004 GeneOrGeneProduct denotes IL-6
T29 994-998 GeneOrGeneProduct denotes IL-1
T28 972-977 GeneOrGeneProduct denotes IL-10
T27 834-839 GeneOrGeneProduct denotes CSF-1
T26 829-833 GeneOrGeneProduct denotes IL-3
T25 820-824 GeneOrGeneProduct denotes IL-3
T24 754-759 GeneOrGeneProduct denotes CSF-1
T23 749-753 GeneOrGeneProduct denotes IL-3
T22 741-745 GeneOrGeneProduct denotes IL-3
T21 717-722 GeneOrGeneProduct denotes CD11c
T20 687-692 GeneOrGeneProduct denotes c-Fos
T19 646-651 GeneOrGeneProduct denotes CD11c
T18 633-637 GeneOrGeneProduct denotes IL-3
T17 592-598 GeneOrGeneProduct denotes CSF-1R
T16 586-591 GeneOrGeneProduct denotes CSF-1
T15 504-508 GeneOrGeneProduct denotes mast
T14 482-490 GeneOrGeneProduct denotes dampened
T13 468-477 GeneOrGeneProduct denotes expansion
T12 456-461 GeneOrGeneProduct denotes CD11c
T11 444-448 GeneOrGeneProduct denotes IL-3
T10 415-420 GeneOrGeneProduct denotes CSF-1
T9 386-390 GeneOrGeneProduct denotes IL-3
T8 377-382 GeneOrGeneProduct denotes CSF-1
T7 344-353 GeneOrGeneProduct denotes uncovered
T6 263-268 GeneOrGeneProduct denotes CSF-1
T5 195-199 GeneOrGeneProduct denotes IL-3
T4 56-61 GeneOrGeneProduct denotes IL-10
T3 49-54 GeneOrGeneProduct denotes CD11c
T2 9-14 GeneOrGeneProduct denotes CSF-1
T72364 0-4 GeneOrGeneProduct denotes IL-3