PubMed:24632946 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/24632946","sourcedb":"PubMed","sourceid":"24632946","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/24632946","text":"Disruption of the temporally regulated cloaca endodermal β-catenin signaling causes anorectal malformations.\nThe cloaca is temporally formed and eventually divided by the urorectal septum (URS) during urogenital and anorectal organ development. Although congenital malformations, such as anorectal malformations (ARMs), are frequently observed during this process, the underlying pathogenic mechanisms remain unclear. β-Catenin is a critical component of canonical Wnt signaling and is essential for the regulation of cell differentiation and morphogenesis during embryogenesis. The expression of β-catenin is observed in endodermal epithelia, including URS epithelia. We modulated the β-catenin gene conditionally in endodermal epithelia by utilizing tamoxifen-inducible Cre driver line (Shh(CreERT2)). Both β-catenin loss- and gain-of-function (LOF and GOF) mutants displayed abnormal clefts in the perineal region and hypoplastic elongation of the URS. The mutants also displayed reduced cell proliferation in the URS mesenchyme. In addition, the β-catenin GOF mutants displayed reduced apoptosis and subsequently increased apoptosis in the URS epithelium. This instability possibly resulted in reduced expression levels of differentiation markers, such as keratin 1 and filaggrin, in the perineal epithelia. The expression of bone morphogenetic protein (Bmp) genes, such as Bmp4 and Bmp7, was also ectopically induced in the epithelia of the URS in the β-catenin GOF mutants. The expression of the Msx2 gene and phosphorylated-Smad1/5/8, possible readouts of Bmp signaling, was also increased in the mutants. Moreover, we introduced an additional mutation for a Bmp receptor gene: BmprIA. The Shh(CreERT2/+); β-catenin(flox(ex3)/+); BmprIA(flox/-) mutants displayed partial restoration of URS elongation compared with the β-catenin GOF mutants. These results indicate that some ARM phenotypes in the β-catenin GOF mutants were caused by abnormal Bmp signaling. The current analysis revealed the close relation of endodermal β-catenin signaling to the ARM phenotypes. These results are considered to shed light on the pathogenic mechanisms of human ARMs.","tracks":[{"project":"sonoma2","denotations":[{"id":"T0","span":{"begin":0,"end":10},"obj":"VAR"},{"id":"T1","span":{"begin":57,"end":69},"obj":"GENE"},{"id":"T2","span":{"begin":77,"end":83},"obj":"REG"},{"id":"T3","span":{"begin":84,"end":107},"obj":"DISEASE"},{"id":"T4","span":{"begin":87,"end":110},"obj":"DISEASE"},{"id":"T5","span":{"begin":257,"end":281},"obj":"DISEASE"},{"id":"T6","span":{"begin":288,"end":311},"obj":"DISEASE"},{"id":"T7","span":{"begin":291,"end":314},"obj":"DISEASE"},{"id":"T8","span":{"begin":313,"end":317},"obj":"DISEASE"},{"id":"T9","span":{"begin":421,"end":433},"obj":"GENE"},{"id":"T10","span":{"begin":603,"end":615},"obj":"GENE"},{"id":"T11","span":{"begin":631,"end":651},"obj":"DISEASE"},{"id":"T12","span":{"begin":663,"end":676},"obj":"DISEASE"},{"id":"T13","span":{"begin":672,"end":681},"obj":"VAR"},{"id":"T14","span":{"begin":686,"end":695},"obj":"GENE"},{"id":"T15","span":{"begin":695,"end":707},"obj":"GENE"},{"id":"T16","span":{"begin":730,"end":750},"obj":"DISEASE"},{"id":"T17","span":{"begin":789,"end":800},"obj":"GENE"},{"id":"T18","span":{"begin":809,"end":818},"obj":"GENE"},{"id":"T19","span":{"begin":819,"end":824},"obj":"NEGREG"},{"id":"T20","span":{"begin":821,"end":833},"obj":"GENE"},{"id":"T21","span":{"begin":829,"end":845},"obj":"POSREG"},{"id":"T22","span":{"begin":855,"end":858},"obj":"POSREG"},{"id":"T23","span":{"begin":860,"end":867},"obj":"VAR"},{"id":"T24","span":{"begin":868,"end":877},"obj":"REG"},{"id":"T25","span":{"begin":887,"end":893},"obj":"CPA"},{"id":"T26","span":{"begin":921,"end":932},"obj":"NEGREG"},{"id":"T27","span":{"begin":933,"end":943},"obj":"CPA"},{"id":"T28","span":{"begin":936,"end":947},"obj":"DISEASE"},{"id":"T29","span":{"begin":960,"end":967},"obj":"VAR"},{"id":"T30","span":{"begin":983,"end":990},"obj":"NEGREG"},{"id":"T31","span":{"begin":991,"end":1009},"obj":"CPA"},{"id":"T32","span":{"begin":1050,"end":1059},"obj":"GENE"},{"id":"T33","span":{"begin":1060,"end":1071},"obj":"VAR"},{"id":"T34","span":{"begin":1065,"end":1077},"obj":"GENE"},{"id":"T35","span":{"begin":1082,"end":1089},"obj":"NEGREG"},{"id":"T36","span":{"begin":1090,"end":1099},"obj":"CPA"},{"id":"T37","span":{"begin":1117,"end":1126},"obj":"POSREG"},{"id":"T38","span":{"begin":1127,"end":1136},"obj":"CPA"},{"id":"T39","span":{"begin":1198,"end":1205},"obj":"NEGREG"},{"id":"T40","span":{"begin":1206,"end":1216},"obj":"MPA"},{"id":"T41","span":{"begin":1316,"end":1326},"obj":"MPA"},{"id":"T42","span":{"begin":1348,"end":1374},"obj":"GENE"},{"id":"T43","span":{"begin":1358,"end":1361},"obj":"GENE"},{"id":"T44","span":{"begin":1376,"end":1379},"obj":"GENE"},{"id":"T45","span":{"begin":1378,"end":1382},"obj":"GENE"},{"id":"T46","span":{"begin":1387,"end":1391},"obj":"GENE"},{"id":"T47","span":{"begin":1396,"end":1400},"obj":"GENE"},{"id":"T48","span":{"begin":1405,"end":1409},"obj":"GENE"},{"id":"T49","span":{"begin":1414,"end":1421},"obj":"POSREG"},{"id":"T50","span":{"begin":1457,"end":1466},"obj":"GENE"},{"id":"T51","span":{"begin":1467,"end":1478},"obj":"VAR"},{"id":"T52","span":{"begin":1475,"end":1487},"obj":"GENE"},{"id":"T53","span":{"begin":1484,"end":1494},"obj":"MPA"},{"id":"T54","span":{"begin":1502,"end":1506},"obj":"GENE"},{"id":"T55","span":{"begin":1516,"end":1540},"obj":"GENE"},{"id":"T56","span":{"begin":1523,"end":1527},"obj":"GENE"},{"id":"T57","span":{"begin":1584,"end":1587},"obj":"GENE"},{"id":"T58","span":{"begin":1587,"end":1596},"obj":"POSREG"},{"id":"T59","span":{"begin":1604,"end":1611},"obj":"VAR"},{"id":"T60","span":{"begin":1651,"end":1659},"obj":"VAR"},{"id":"T61","span":{"begin":1685,"end":1691},"obj":"GENE"},{"id":"T62","span":{"begin":1687,"end":1690},"obj":"GENE"},{"id":"T63","span":{"begin":1734,"end":1758},"obj":"GENE"},{"id":"T64","span":{"begin":1752,"end":1759},"obj":"VAR"},{"id":"T65","span":{"begin":1778,"end":1789},"obj":"NEGREG"},{"id":"T66","span":{"begin":1793,"end":1807},"obj":"MPA"},{"id":"T67","span":{"begin":1826,"end":1835},"obj":"GENE"},{"id":"T68","span":{"begin":1836,"end":1847},"obj":"VAR"},{"id":"T69","span":{"begin":1850,"end":1862},"obj":"GENE"},{"id":"T70","span":{"begin":1882,"end":1885},"obj":"DISEASE"},{"id":"T71","span":{"begin":1886,"end":1896},"obj":"CPA"},{"id":"T72","span":{"begin":1904,"end":1913},"obj":"GENE"},{"id":"T73","span":{"begin":1914,"end":1925},"obj":"VAR"},{"id":"T74","span":{"begin":1931,"end":1937},"obj":"REG"},{"id":"T75","span":{"begin":1931,"end":1943},"obj":"GENE"},{"id":"T76","span":{"begin":1980,"end":1983},"obj":"GENE"},{"id":"T77","span":{"begin":2058,"end":2070},"obj":"GENE"},{"id":"T78","span":{"begin":2152,"end":2156},"obj":"DISEASE"}],"relations":[{"id":"R0","pred":"CauseOf","subj":"T0","obj":"T2"},{"id":"R1","pred":"ThemeOf","subj":"T3","obj":"T2"},{"id":"R2","pred":"ThemeOf","subj":"T6","obj":"T8"},{"id":"R3","pred":"ThemeOf","subj":"T14","obj":"T13"},{"id":"R4","pred":"ThemeOf","subj":"T18","obj":"T23"},{"id":"R5","pred":"CauseOf","subj":"T19","obj":"T21"},{"id":"R6","pred":"CauseOf","subj":"T22","obj":"T19"},{"id":"R7","pred":"CauseOf","subj":"T19","obj":"T24"},{"id":"R8","pred":"CauseOf","subj":"T19","obj":"T26"},{"id":"R9","pred":"CauseOf","subj":"T22","obj":"T21"},{"id":"R10","pred":"CauseOf","subj":"T21","obj":"T24"},{"id":"R11","pred":"CauseOf","subj":"T21","obj":"T26"},{"id":"R12","pred":"CauseOf","subj":"T22","obj":"T24"},{"id":"R13","pred":"CauseOf","subj":"T22","obj":"T26"},{"id":"R14","pred":"CauseOf","subj":"T23","obj":"T19"},{"id":"R15","pred":"CauseOf","subj":"T23","obj":"T21"},{"id":"R16","pred":"CauseOf","subj":"T23","obj":"T22"},{"id":"R17","pred":"CauseOf","subj":"T23","obj":"T24"},{"id":"R18","pred":"CauseOf","subj":"T23","obj":"T26"},{"id":"R19","pred":"ThemeOf","subj":"T25","obj":"T24"},{"id":"R20","pred":"ThemeOf","subj":"T27","obj":"T24"},{"id":"R21","pred":"ThemeOf","subj":"T27","obj":"T26"},{"id":"R22","pred":"CauseOf","subj":"T29","obj":"T30"},{"id":"R23","pred":"ThemeOf","subj":"T31","obj":"T30"},{"id":"R24","pred":"ThemeOf","subj":"T32","obj":"T33"},{"id":"R25","pred":"CauseOf","subj":"T33","obj":"T35"},{"id":"R26","pred":"CauseOf","subj":"T33","obj":"T37"},{"id":"R27","pred":"ThemeOf","subj":"T36","obj":"T35"},{"id":"R28","pred":"ThemeOf","subj":"T38","obj":"T37"},{"id":"R29","pred":"ThemeOf","subj":"T40","obj":"T39"},{"id":"R30","pred":"ThemeOf","subj":"T41","obj":"T49"},{"id":"R31","pred":"ThemeOf","subj":"T43","obj":"T41"},{"id":"R32","pred":"ThemeOf","subj":"T45","obj":"T41"},{"id":"R33","pred":"ThemeOf","subj":"T46","obj":"T41"},{"id":"R34","pred":"ThemeOf","subj":"T50","obj":"T51"},{"id":"R35","pred":"CauseOf","subj":"T51","obj":"T49"},{"id":"R36","pred":"ThemeOf","subj":"T53","obj":"T58"},{"id":"R37","pred":"ThemeOf","subj":"T54","obj":"T53"},{"id":"R38","pred":"ThemeOf","subj":"T55","obj":"T53"},{"id":"R39","pred":"CauseOf","subj":"T59","obj":"T58"},{"id":"R40","pred":"CauseOf","subj":"T60","obj":"T65"},{"id":"R41","pred":"ThemeOf","subj":"T61","obj":"T60"},{"id":"R42","pred":"ThemeOf","subj":"T61","obj":"T64"},{"id":"R43","pred":"CauseOf","subj":"T64","obj":"T65"},{"id":"R44","pred":"ThemeOf","subj":"T66","obj":"T65"},{"id":"R45","pred":"ThemeOf","subj":"T67","obj":"T68"},{"id":"R46","pred":"CauseOf","subj":"T68","obj":"T65"},{"id":"R47","pred":"ThemeOf","subj":"T70","obj":"T71"},{"id":"R48","pred":"CauseOf","subj":"T73","obj":"T70"},{"id":"R49","pred":"ThemeOf","subj":"T70","obj":"T74"},{"id":"R50","pred":"CauseOf","subj":"T73","obj":"T71"},{"id":"R51","pred":"ThemeOf","subj":"T71","obj":"T74"},{"id":"R52","pred":"ThemeOf","subj":"T72","obj":"T71"},{"id":"R53","pred":"ThemeOf","subj":"T72","obj":"T73"},{"id":"R54","pred":"CauseOf","subj":"T73","obj":"T74"}],"attributes":[{"subj":"T0","pred":"source","obj":"sonoma2"},{"subj":"T1","pred":"source","obj":"sonoma2"},{"subj":"T2","pred":"source","obj":"sonoma2"},{"subj":"T3","pred":"source","obj":"sonoma2"},{"subj":"T4","pred":"source","obj":"sonoma2"},{"subj":"T5","pred":"source","obj":"sonoma2"},{"subj":"T6","pred":"source","obj":"sonoma2"},{"subj":"T7","pred":"source","obj":"sonoma2"},{"subj":"T8","pred":"source","obj":"sonoma2"},{"subj":"T9","pred":"source","obj":"sonoma2"},{"subj":"T10","pred":"source","obj":"sonoma2"},{"subj":"T11","pred":"source","obj":"sonoma2"},{"subj":"T12","pred":"source","obj":"sonoma2"},{"subj":"T13","pred":"source","obj":"sonoma2"},{"subj":"T14","pred":"source","obj":"sonoma2"},{"subj":"T15","pred":"source","obj":"sonoma2"},{"subj":"T16","pred":"source","obj":"sonoma2"},{"subj":"T17","pred":"source","obj":"sonoma2"},{"subj":"T18","pred":"source","obj":"sonoma2"},{"subj":"T19","pred":"source","obj":"sonoma2"},{"subj":"T20","pred":"source","obj":"sonoma2"},{"subj":"T21","pred":"source","obj":"sonoma2"},{"subj":"T22","pred":"source","obj":"sonoma2"},{"subj":"T23","pred":"source","obj":"sonoma2"},{"subj":"T24","pred":"source","obj":"sonoma2"},{"subj":"T25","pred":"source","obj":"sonoma2"},{"subj":"T26","pred":"source","obj":"sonoma2"},{"subj":"T27","pred":"source","obj":"sonoma2"},{"subj":"T28","pred":"source","obj":"sonoma2"},{"subj":"T29","pred":"source","obj":"sonoma2"},{"subj":"T30","pred":"source","obj":"sonoma2"},{"subj":"T31","pred":"source","obj":"sonoma2"},{"subj":"T32","pred":"source","obj":"sonoma2"},{"subj":"T33","pred":"source","obj":"sonoma2"},{"subj":"T34","pred":"source","obj":"sonoma2"},{"subj":"T35","pred":"source","obj":"sonoma2"},{"subj":"T36","pred":"source","obj":"sonoma2"},{"subj":"T37","pred":"source","obj":"sonoma2"},{"subj":"T38","pred":"source","obj":"sonoma2"},{"subj":"T39","pred":"source","obj":"sonoma2"},{"subj":"T40","pred":"source","obj":"sonoma2"},{"subj":"T41","pred":"source","obj":"sonoma2"},{"subj":"T42","pred":"source","obj":"sonoma2"},{"subj":"T43","pred":"source","obj":"sonoma2"},{"subj":"T44","pred":"source","obj":"sonoma2"},{"subj":"T45","pred":"source","obj":"sonoma2"},{"subj":"T46","pred":"source","obj":"sonoma2"},{"subj":"T47","pred":"source","obj":"sonoma2"},{"subj":"T48","pred":"source","obj":"sonoma2"},{"subj":"T49","pred":"source","obj":"sonoma2"},{"subj":"T50","pred":"source","obj":"sonoma2"},{"subj":"T51","pred":"source","obj":"sonoma2"},{"subj":"T52","pred":"source","obj":"sonoma2"},{"subj":"T53","pred":"source","obj":"sonoma2"},{"subj":"T54","pred":"source","obj":"sonoma2"},{"subj":"T55","pred":"source","obj":"sonoma2"},{"subj":"T56","pred":"source","obj":"sonoma2"},{"subj":"T57","pred":"source","obj":"sonoma2"},{"subj":"T58","pred":"source","obj":"sonoma2"},{"subj":"T59","pred":"source","obj":"sonoma2"},{"subj":"T60","pred":"source","obj":"sonoma2"},{"subj":"T61","pred":"source","obj":"sonoma2"},{"subj":"T62","pred":"source","obj":"sonoma2"},{"subj":"T63","pred":"source","obj":"sonoma2"},{"subj":"T64","pred":"source","obj":"sonoma2"},{"subj":"T65","pred":"source","obj":"sonoma2"},{"subj":"T66","pred":"source","obj":"sonoma2"},{"subj":"T67","pred":"source","obj":"sonoma2"},{"subj":"T68","pred":"source","obj":"sonoma2"},{"subj":"T69","pred":"source","obj":"sonoma2"},{"subj":"T70","pred":"source","obj":"sonoma2"},{"subj":"T71","pred":"source","obj":"sonoma2"},{"subj":"T72","pred":"source","obj":"sonoma2"},{"subj":"T73","pred":"source","obj":"sonoma2"},{"subj":"T74","pred":"source","obj":"sonoma2"},{"subj":"T75","pred":"source","obj":"sonoma2"},{"subj":"T76","pred":"source","obj":"sonoma2"},{"subj":"T77","pred":"source","obj":"sonoma2"},{"subj":"T78","pred":"source","obj":"sonoma2"}]},{"project":"LitCoin-entities","denotations":[{"id":"9784","span":{"begin":57,"end":66},"obj":"GeneOrGeneProduct"},{"id":"9785","span":{"begin":84,"end":107},"obj":"DiseaseOrPhenotypicFeature"},{"id":"9786","span":{"begin":254,"end":278},"obj":"DiseaseOrPhenotypicFeature"},{"id":"9787","span":{"begin":288,"end":311},"obj":"DiseaseOrPhenotypicFeature"},{"id":"9788","span":{"begin":313,"end":317},"obj":"DiseaseOrPhenotypicFeature"},{"id":"9789","span":{"begin":418,"end":427},"obj":"GeneOrGeneProduct"},{"id":"9790","span":{"begin":465,"end":468},"obj":"GeneOrGeneProduct"},{"id":"9791","span":{"begin":597,"end":606},"obj":"GeneOrGeneProduct"},{"id":"9792","span":{"begin":686,"end":695},"obj":"GeneOrGeneProduct"},{"id":"9793","span":{"begin":752,"end":761},"obj":"ChemicalEntity"},{"id":"9794","span":{"begin":789,"end":792},"obj":"GeneOrGeneProduct"},{"id":"9795","span":{"begin":809,"end":818},"obj":"GeneOrGeneProduct"},{"id":"9796","span":{"begin":921,"end":932},"obj":"DiseaseOrPhenotypicFeature"},{"id":"9797","span":{"begin":1050,"end":1059},"obj":"GeneOrGeneProduct"},{"id":"9798","span":{"begin":1260,"end":1269},"obj":"GeneOrGeneProduct"},{"id":"9799","span":{"begin":1274,"end":1283},"obj":"GeneOrGeneProduct"},{"id":"9800","span":{"begin":1330,"end":1356},"obj":"GeneOrGeneProduct"},{"id":"9801","span":{"begin":1358,"end":1361},"obj":"GeneOrGeneProduct"},{"id":"9802","span":{"begin":1378,"end":1382},"obj":"GeneOrGeneProduct"},{"id":"9803","span":{"begin":1387,"end":1391},"obj":"GeneOrGeneProduct"},{"id":"9804","span":{"begin":1457,"end":1466},"obj":"GeneOrGeneProduct"},{"id":"9805","span":{"begin":1502,"end":1506},"obj":"GeneOrGeneProduct"},{"id":"9806","span":{"begin":1531,"end":1540},"obj":"GeneOrGeneProduct"},{"id":"9807","span":{"begin":1563,"end":1566},"obj":"GeneOrGeneProduct"},{"id":"9808","span":{"begin":1666,"end":1678},"obj":"GeneOrGeneProduct"},{"id":"9809","span":{"begin":1685,"end":1691},"obj":"GeneOrGeneProduct"},{"id":"9810","span":{"begin":1697,"end":1700},"obj":"GeneOrGeneProduct"},{"id":"9811","span":{"begin":1713,"end":1722},"obj":"GeneOrGeneProduct"},{"id":"9812","span":{"begin":1737,"end":1743},"obj":"GeneOrGeneProduct"},{"id":"9813","span":{"begin":1826,"end":1835},"obj":"GeneOrGeneProduct"},{"id":"9814","span":{"begin":1882,"end":1885},"obj":"DiseaseOrPhenotypicFeature"},{"id":"9815","span":{"begin":1904,"end":1913},"obj":"GeneOrGeneProduct"},{"id":"9816","span":{"begin":1950,"end":1953},"obj":"GeneOrGeneProduct"},{"id":"9817","span":{"begin":2028,"end":2037},"obj":"GeneOrGeneProduct"},{"id":"9818","span":{"begin":2055,"end":2058},"obj":"DiseaseOrPhenotypicFeature"},{"id":"9819","span":{"begin":2146,"end":2151},"obj":"OrganismTaxon"},{"id":"9820","span":{"begin":2152,"end":2156},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A1","pred":"db_id","subj":"9784","obj":"NCBIGene:12387"},{"id":"A2","pred":"db_id","subj":"9785","obj":"MESH:D000071056"},{"id":"A3","pred":"db_id","subj":"9786","obj":"MESH:D000013"},{"id":"A4","pred":"db_id","subj":"9787","obj":"MESH:D000071056"},{"id":"A5","pred":"db_id","subj":"9788","obj":"MESH:D000071056"},{"id":"A6","pred":"db_id","subj":"9789","obj":"NCBIGene:12387"},{"id":"A7","pred":"db_id","subj":"9790","obj":"NCBIGene:22408"},{"id":"A8","pred":"db_id","subj":"9791","obj":"NCBIGene:12387"},{"id":"A9","pred":"db_id","subj":"9792","obj":"NCBIGene:12387"},{"id":"A10","pred":"db_id","subj":"9793","obj":"MESH:D013629"},{"id":"A11","pred":"db_id","subj":"9794","obj":"NCBIGene:20423"},{"id":"A12","pred":"db_id","subj":"9795","obj":"NCBIGene:12387"},{"id":"A13","pred":"db_id","subj":"9796","obj":"MESH:D029502"},{"id":"A14","pred":"db_id","subj":"9797","obj":"NCBIGene:12387"},{"id":"A15","pred":"db_id","subj":"9798","obj":"NCBIGene:16678"},{"id":"A16","pred":"db_id","subj":"9799","obj":"NCBIGene:14246"},{"id":"A17","pred":"db_id","subj":"9800","obj":"NCBIGene:12159"},{"id":"A18","pred":"db_id","subj":"9800","obj":"NCBIGene:12162"},{"id":"A19","pred":"db_id","subj":"9801","obj":"NCBIGene:12159"},{"id":"A20","pred":"db_id","subj":"9801","obj":"NCBIGene:12162"},{"id":"A21","pred":"db_id","subj":"9802","obj":"NCBIGene:12159"},{"id":"A22","pred":"db_id","subj":"9803","obj":"NCBIGene:12162"},{"id":"A23","pred":"db_id","subj":"9804","obj":"NCBIGene:12387"},{"id":"A24","pred":"db_id","subj":"9805","obj":"NCBIGene:17702"},{"id":"A25","pred":"db_id","subj":"9806","obj":"NCBIGene:17125"},{"id":"A26","pred":"db_id","subj":"9806","obj":"NCBIGene:17129"},{"id":"A27","pred":"db_id","subj":"9806","obj":"NCBIGene:55994"},{"id":"A28","pred":"db_id","subj":"9807","obj":"NCBIGene:12159"},{"id":"A29","pred":"db_id","subj":"9807","obj":"NCBIGene:12162"},{"id":"A30","pred":"db_id","subj":"9808","obj":"NCBIGene:12166"},{"id":"A31","pred":"db_id","subj":"9809","obj":"NCBIGene:12166"},{"id":"A32","pred":"db_id","subj":"9810","obj":"NCBIGene:20423"},{"id":"A33","pred":"db_id","subj":"9811","obj":"NCBIGene:12387"},{"id":"A34","pred":"db_id","subj":"9812","obj":"NCBIGene:12166"},{"id":"A35","pred":"db_id","subj":"9813","obj":"NCBIGene:12387"},{"id":"A36","pred":"db_id","subj":"9814","obj":"MESH:D000071056"},{"id":"A37","pred":"db_id","subj":"9815","obj":"NCBIGene:12387"},{"id":"A38","pred":"db_id","subj":"9816","obj":"NCBIGene:12159"},{"id":"A39","pred":"db_id","subj":"9816","obj":"NCBIGene:12162"},{"id":"A40","pred":"db_id","subj":"9817","obj":"NCBIGene:12387"},{"id":"A41","pred":"db_id","subj":"9818","obj":"MESH:D000071056"},{"id":"A42","pred":"db_id","subj":"9819","obj":"NCBITaxon:9606"},{"id":"A43","pred":"db_id","subj":"9820","obj":"MESH:D000071056"},{"subj":"9784","pred":"source","obj":"LitCoin-entities"},{"subj":"9785","pred":"source","obj":"LitCoin-entities"},{"subj":"9786","pred":"source","obj":"LitCoin-entities"},{"subj":"9787","pred":"source","obj":"LitCoin-entities"},{"subj":"9788","pred":"source","obj":"LitCoin-entities"},{"subj":"9789","pred":"source","obj":"LitCoin-entities"},{"subj":"9790","pred":"source","obj":"LitCoin-entities"},{"subj":"9791","pred":"source","obj":"LitCoin-entities"},{"subj":"9792","pred":"source","obj":"LitCoin-entities"},{"subj":"9793","pred":"source","obj":"LitCoin-entities"},{"subj":"9794","pred":"source","obj":"LitCoin-entities"},{"subj":"9795","pred":"source","obj":"LitCoin-entities"},{"subj":"9796","pred":"source","obj":"LitCoin-entities"},{"subj":"9797","pred":"source","obj":"LitCoin-entities"},{"subj":"9798","pred":"source","obj":"LitCoin-entities"},{"subj":"9799","pred":"source","obj":"LitCoin-entities"},{"subj":"9800","pred":"source","obj":"LitCoin-entities"},{"subj":"9801","pred":"source","obj":"LitCoin-entities"},{"subj":"9802","pred":"source","obj":"LitCoin-entities"},{"subj":"9803","pred":"source","obj":"LitCoin-entities"},{"subj":"9804","pred":"source","obj":"LitCoin-entities"},{"subj":"9805","pred":"source","obj":"LitCoin-entities"},{"subj":"9806","pred":"source","obj":"LitCoin-entities"},{"subj":"9807","pred":"source","obj":"LitCoin-entities"},{"subj":"9808","pred":"source","obj":"LitCoin-entities"},{"subj":"9809","pred":"source","obj":"LitCoin-entities"},{"subj":"9810","pred":"source","obj":"LitCoin-entities"},{"subj":"9811","pred":"source","obj":"LitCoin-entities"},{"subj":"9812","pred":"source","obj":"LitCoin-entities"},{"subj":"9813","pred":"source","obj":"LitCoin-entities"},{"subj":"9814","pred":"source","obj":"LitCoin-entities"},{"subj":"9815","pred":"source","obj":"LitCoin-entities"},{"subj":"9816","pred":"source","obj":"LitCoin-entities"},{"subj":"9817","pred":"source","obj":"LitCoin-entities"},{"subj":"9818","pred":"source","obj":"LitCoin-entities"},{"subj":"9819","pred":"source","obj":"LitCoin-entities"},{"subj":"9820","pred":"source","obj":"LitCoin-entities"}],"namespaces":[{"prefix":"_base","uri":"https://w3id.org/biolink/vocab/"},{"prefix":"MESH","uri":"http://id.nlm.nih.gov/mesh/"},{"prefix":"NCBITaxon","uri":"https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id="},{"prefix":"NCBIGene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"OMIM","uri":"https://www.omim.org/entry/"},{"prefix":"DBSNP","uri":"https://www.ncbi.nlm.nih.gov/snp/"}]},{"project":"LitCoin-entities-OrganismTaxon-PD","denotations":[{"id":"T1","span":{"begin":39,"end":45},"obj":"OrganismTaxon"},{"id":"T2","span":{"begin":113,"end":119},"obj":"OrganismTaxon"},{"id":"T3","span":{"begin":2146,"end":2151},"obj":"OrganismTaxon"}],"attributes":[{"id":"A1","pred":"db_id","subj":"T1","obj":"NCBItxid:547"},{"id":"A2","pred":"db_id","subj":"T2","obj":"NCBItxid:547"},{"id":"A3","pred":"db_id","subj":"T3","obj":"NCBItxid:9606"},{"subj":"T1","pred":"source","obj":"LitCoin-entities-OrganismTaxon-PD"},{"subj":"T2","pred":"source","obj":"LitCoin-entities-OrganismTaxon-PD"},{"subj":"T3","pred":"source","obj":"LitCoin-entities-OrganismTaxon-PD"}]},{"project":"LitCoin-sentences","denotations":[{"id":"T1","span":{"begin":0,"end":108},"obj":"Sentence"},{"id":"T2","span":{"begin":109,"end":244},"obj":"Sentence"},{"id":"T3","span":{"begin":245,"end":578},"obj":"Sentence"},{"id":"T4","span":{"begin":579,"end":668},"obj":"Sentence"},{"id":"T5","span":{"begin":669,"end":803},"obj":"Sentence"},{"id":"T6","span":{"begin":804,"end":955},"obj":"Sentence"},{"id":"T7","span":{"begin":956,"end":1032},"obj":"Sentence"},{"id":"T8","span":{"begin":1033,"end":1159},"obj":"Sentence"},{"id":"T9","span":{"begin":1160,"end":1311},"obj":"Sentence"},{"id":"T10","span":{"begin":1312,"end":1479},"obj":"Sentence"},{"id":"T11","span":{"begin":1480,"end":1612},"obj":"Sentence"},{"id":"T12","span":{"begin":1613,"end":1684},"obj":"Sentence"},{"id":"T13","span":{"begin":1685,"end":1692},"obj":"Sentence"},{"id":"T14","span":{"begin":1693,"end":1848},"obj":"Sentence"},{"id":"T15","span":{"begin":1849,"end":1964},"obj":"Sentence"},{"id":"T16","span":{"begin":1965,"end":2070},"obj":"Sentence"},{"id":"T17","span":{"begin":2071,"end":2157},"obj":"Sentence"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCoin-sentences"},{"subj":"T2","pred":"source","obj":"LitCoin-sentences"},{"subj":"T3","pred":"source","obj":"LitCoin-sentences"},{"subj":"T4","pred":"source","obj":"LitCoin-sentences"},{"subj":"T5","pred":"source","obj":"LitCoin-sentences"},{"subj":"T6","pred":"source","obj":"LitCoin-sentences"},{"subj":"T7","pred":"source","obj":"LitCoin-sentences"},{"subj":"T8","pred":"source","obj":"LitCoin-sentences"},{"subj":"T9","pred":"source","obj":"LitCoin-sentences"},{"subj":"T10","pred":"source","obj":"LitCoin-sentences"},{"subj":"T11","pred":"source","obj":"LitCoin-sentences"},{"subj":"T12","pred":"source","obj":"LitCoin-sentences"},{"subj":"T13","pred":"source","obj":"LitCoin-sentences"},{"subj":"T14","pred":"source","obj":"LitCoin-sentences"},{"subj":"T15","pred":"source","obj":"LitCoin-sentences"},{"subj":"T16","pred":"source","obj":"LitCoin-sentences"},{"subj":"T17","pred":"source","obj":"LitCoin-sentences"}]},{"project":"LitCoin_Mondo","denotations":[{"id":"T1","span":{"begin":84,"end":107},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":254,"end":264},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":288,"end":311},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A1","pred":"mondo_id","subj":"T1","obj":"0019938"},{"id":"A2","pred":"mondo_id","subj":"T2","obj":"0021140"},{"id":"A3","pred":"mondo_id","subj":"T3","obj":"0019938"},{"subj":"T1","pred":"source","obj":"LitCoin_Mondo"},{"subj":"T2","pred":"source","obj":"LitCoin_Mondo"},{"subj":"T3","pred":"source","obj":"LitCoin_Mondo"}]},{"project":"LitCoin-GeneOrGeneProduct-v0","denotations":[{"id":"T1","span":{"begin":0,"end":10},"obj":"GeneOrGeneProduct"},{"id":"T2","span":{"begin":29,"end":38},"obj":"GeneOrGeneProduct"},{"id":"T3","span":{"begin":59,"end":66},"obj":"GeneOrGeneProduct"},{"id":"T4","span":{"begin":94,"end":107},"obj":"GeneOrGeneProduct"},{"id":"T5","span":{"begin":201,"end":211},"obj":"GeneOrGeneProduct"},{"id":"T6","span":{"begin":265,"end":278},"obj":"GeneOrGeneProduct"},{"id":"T7","span":{"begin":298,"end":311},"obj":"GeneOrGeneProduct"},{"id":"T8","span":{"begin":313,"end":317},"obj":"GeneOrGeneProduct"},{"id":"T9","span":{"begin":356,"end":363},"obj":"GeneOrGeneProduct"},{"id":"T10","span":{"begin":409,"end":416},"obj":"GeneOrGeneProduct"},{"id":"T11","span":{"begin":420,"end":427},"obj":"GeneOrGeneProduct"},{"id":"T12","span":{"begin":504,"end":514},"obj":"GeneOrGeneProduct"},{"id":"T13","span":{"begin":518,"end":538},"obj":"GeneOrGeneProduct"},{"id":"T14","span":{"begin":599,"end":606},"obj":"GeneOrGeneProduct"},{"id":"T15","span":{"begin":688,"end":695},"obj":"GeneOrGeneProduct"},{"id":"T16","span":{"begin":762,"end":771},"obj":"GeneOrGeneProduct"},{"id":"T17","span":{"begin":783,"end":787},"obj":"GeneOrGeneProduct"},{"id":"T18","span":{"begin":811,"end":818},"obj":"GeneOrGeneProduct"},{"id":"T19","span":{"begin":860,"end":867},"obj":"GeneOrGeneProduct"},{"id":"T20","span":{"begin":887,"end":893},"obj":"GeneOrGeneProduct"},{"id":"T21","span":{"begin":933,"end":943},"obj":"GeneOrGeneProduct"},{"id":"T22","span":{"begin":960,"end":967},"obj":"GeneOrGeneProduct"},{"id":"T23","span":{"begin":983,"end":990},"obj":"GeneOrGeneProduct"},{"id":"T24","span":{"begin":991,"end":995},"obj":"GeneOrGeneProduct"},{"id":"T25","span":{"begin":1052,"end":1059},"obj":"GeneOrGeneProduct"},{"id":"T45","span":{"begin":1666,"end":1669},"obj":"GeneOrGeneProduct"},{"id":"T26","span":{"begin":1064,"end":1071},"obj":"GeneOrGeneProduct"},{"id":"T27","span":{"begin":1082,"end":1089},"obj":"GeneOrGeneProduct"},{"id":"T28","span":{"begin":1090,"end":1099},"obj":"GeneOrGeneProduct"},{"id":"T29","span":{"begin":1127,"end":1136},"obj":"GeneOrGeneProduct"},{"id":"T30","span":{"begin":1198,"end":1205},"obj":"GeneOrGeneProduct"},{"id":"T31","span":{"begin":1260,"end":1269},"obj":"GeneOrGeneProduct"},{"id":"T32","span":{"begin":1274,"end":1283},"obj":"GeneOrGeneProduct"},{"id":"T33","span":{"begin":1330,"end":1356},"obj":"GeneOrGeneProduct"},{"id":"T34","span":{"begin":1358,"end":1361},"obj":"GeneOrGeneProduct"},{"id":"T35","span":{"begin":1378,"end":1382},"obj":"GeneOrGeneProduct"},{"id":"T36","span":{"begin":1387,"end":1391},"obj":"GeneOrGeneProduct"},{"id":"T37","span":{"begin":1414,"end":1421},"obj":"GeneOrGeneProduct"},{"id":"T38","span":{"begin":1459,"end":1466},"obj":"GeneOrGeneProduct"},{"id":"T39","span":{"begin":1471,"end":1478},"obj":"GeneOrGeneProduct"},{"id":"T40","span":{"begin":1502,"end":1506},"obj":"GeneOrGeneProduct"},{"id":"T41","span":{"begin":1531,"end":1538},"obj":"GeneOrGeneProduct"},{"id":"T42","span":{"begin":1563,"end":1566},"obj":"GeneOrGeneProduct"},{"id":"T43","span":{"begin":1604,"end":1611},"obj":"GeneOrGeneProduct"},{"id":"T44","span":{"begin":1651,"end":1659},"obj":"GeneOrGeneProduct"},{"id":"T46","span":{"begin":1670,"end":1678},"obj":"GeneOrGeneProduct"},{"id":"T47","span":{"begin":1685,"end":1691},"obj":"GeneOrGeneProduct"},{"id":"T48","span":{"begin":1715,"end":1722},"obj":"GeneOrGeneProduct"},{"id":"T49","span":{"begin":1737,"end":1743},"obj":"GeneOrGeneProduct"},{"id":"T50","span":{"begin":1752,"end":1759},"obj":"GeneOrGeneProduct"},{"id":"T51","span":{"begin":1797,"end":1807},"obj":"GeneOrGeneProduct"},{"id":"T52","span":{"begin":1828,"end":1835},"obj":"GeneOrGeneProduct"},{"id":"T53","span":{"begin":1840,"end":1847},"obj":"GeneOrGeneProduct"},{"id":"T54","span":{"begin":1882,"end":1885},"obj":"GeneOrGeneProduct"},{"id":"T55","span":{"begin":1906,"end":1913},"obj":"GeneOrGeneProduct"},{"id":"T56","span":{"begin":1918,"end":1925},"obj":"GeneOrGeneProduct"},{"id":"T57","span":{"begin":1950,"end":1953},"obj":"GeneOrGeneProduct"},{"id":"T58","span":{"begin":2030,"end":2037},"obj":"GeneOrGeneProduct"},{"id":"T59","span":{"begin":2055,"end":2058},"obj":"GeneOrGeneProduct"},{"id":"T60","span":{"begin":2108,"end":2113},"obj":"GeneOrGeneProduct"},{"id":"T61","span":{"begin":2152,"end":2156},"obj":"GeneOrGeneProduct"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T2","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T3","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T4","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T5","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T6","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T7","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T8","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T9","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T10","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T11","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T12","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T13","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T14","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T15","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T16","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T17","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T18","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T19","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T20","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T21","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T22","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T23","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T24","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T25","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T45","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T26","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T27","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T28","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T29","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T30","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T31","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T32","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T33","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T34","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T35","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T36","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T37","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T38","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T39","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T40","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T41","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T42","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T43","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T44","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T46","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T47","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T48","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T49","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T50","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T51","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T52","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T53","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T54","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T55","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T56","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T57","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T58","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T59","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T60","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T61","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"}]},{"project":"LitCoin-GeneOrGeneProduct-v2","denotations":[{"id":"T1","span":{"begin":59,"end":66},"obj":"GeneOrGeneProduct"},{"id":"T2","span":{"begin":201,"end":211},"obj":"GeneOrGeneProduct"},{"id":"T3","span":{"begin":409,"end":416},"obj":"GeneOrGeneProduct"},{"id":"T4","span":{"begin":420,"end":427},"obj":"GeneOrGeneProduct"},{"id":"T5","span":{"begin":518,"end":538},"obj":"GeneOrGeneProduct"},{"id":"T6","span":{"begin":599,"end":606},"obj":"GeneOrGeneProduct"},{"id":"T7","span":{"begin":688,"end":695},"obj":"GeneOrGeneProduct"},{"id":"T8","span":{"begin":762,"end":771},"obj":"GeneOrGeneProduct"},{"id":"T9","span":{"begin":811,"end":818},"obj":"GeneOrGeneProduct"},{"id":"T10","span":{"begin":983,"end":990},"obj":"GeneOrGeneProduct"},{"id":"T11","span":{"begin":991,"end":995},"obj":"GeneOrGeneProduct"},{"id":"T12","span":{"begin":1052,"end":1059},"obj":"GeneOrGeneProduct"},{"id":"T13","span":{"begin":1082,"end":1089},"obj":"GeneOrGeneProduct"},{"id":"T14","span":{"begin":1090,"end":1099},"obj":"GeneOrGeneProduct"},{"id":"T15","span":{"begin":1127,"end":1136},"obj":"GeneOrGeneProduct"},{"id":"T16","span":{"begin":1198,"end":1205},"obj":"GeneOrGeneProduct"},{"id":"T17","span":{"begin":1260,"end":1269},"obj":"GeneOrGeneProduct"},{"id":"T18","span":{"begin":1274,"end":1283},"obj":"GeneOrGeneProduct"},{"id":"T19","span":{"begin":1330,"end":1356},"obj":"GeneOrGeneProduct"},{"id":"T20","span":{"begin":1358,"end":1361},"obj":"GeneOrGeneProduct"},{"id":"T21","span":{"begin":1378,"end":1382},"obj":"GeneOrGeneProduct"},{"id":"T22","span":{"begin":1387,"end":1391},"obj":"GeneOrGeneProduct"},{"id":"T23","span":{"begin":1459,"end":1466},"obj":"GeneOrGeneProduct"},{"id":"T24","span":{"begin":1502,"end":1506},"obj":"GeneOrGeneProduct"},{"id":"T25","span":{"begin":1531,"end":1538},"obj":"GeneOrGeneProduct"},{"id":"T26","span":{"begin":1563,"end":1566},"obj":"GeneOrGeneProduct"},{"id":"T27","span":{"begin":1666,"end":1669},"obj":"GeneOrGeneProduct"},{"id":"T28","span":{"begin":1670,"end":1678},"obj":"GeneOrGeneProduct"},{"id":"T29","span":{"begin":1715,"end":1722},"obj":"GeneOrGeneProduct"},{"id":"T30","span":{"begin":1828,"end":1835},"obj":"GeneOrGeneProduct"},{"id":"T31","span":{"begin":1906,"end":1913},"obj":"GeneOrGeneProduct"},{"id":"T32","span":{"begin":1950,"end":1953},"obj":"GeneOrGeneProduct"},{"id":"T33","span":{"begin":2030,"end":2037},"obj":"GeneOrGeneProduct"},{"id":"T34","span":{"begin":2108,"end":2113},"obj":"GeneOrGeneProduct"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T2","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T3","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T4","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T5","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T6","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T7","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T8","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T9","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T10","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T11","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T12","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T13","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T14","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T15","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T16","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T17","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T18","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T19","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T20","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T21","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T22","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T23","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T24","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T25","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T26","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T27","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T28","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T29","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T30","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T31","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T32","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T33","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T34","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"}]},{"project":"LitCoin-Disease-MeSH","denotations":[{"id":"T1","span":{"begin":84,"end":107},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":288,"end":311},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":313,"end":317},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":2152,"end":2156},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A1","pred":"originalLabel","subj":"T1","obj":"D000071056"},{"id":"A2","pred":"originalLabel","subj":"T2","obj":"D000071056"},{"id":"A3","pred":"originalLabel","subj":"T3","obj":"D000071056"},{"id":"A4","pred":"originalLabel","subj":"T4","obj":"D000071056"},{"subj":"T1","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T2","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T3","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T4","pred":"source","obj":"LitCoin-Disease-MeSH"}]},{"project":"LitCoin-GeneOrGeneProduct-v3","denotations":[{"id":"T1","span":{"begin":59,"end":66},"obj":"GeneOrGeneProduct"},{"id":"T2","span":{"begin":201,"end":211},"obj":"GeneOrGeneProduct"},{"id":"T3","span":{"begin":420,"end":427},"obj":"GeneOrGeneProduct"},{"id":"T4","span":{"begin":599,"end":606},"obj":"GeneOrGeneProduct"},{"id":"T5","span":{"begin":688,"end":695},"obj":"GeneOrGeneProduct"},{"id":"T6","span":{"begin":811,"end":818},"obj":"GeneOrGeneProduct"},{"id":"T7","span":{"begin":1052,"end":1059},"obj":"GeneOrGeneProduct"},{"id":"T8","span":{"begin":1260,"end":1269},"obj":"GeneOrGeneProduct"},{"id":"T9","span":{"begin":1274,"end":1283},"obj":"GeneOrGeneProduct"},{"id":"T10","span":{"begin":1330,"end":1356},"obj":"GeneOrGeneProduct"},{"id":"T11","span":{"begin":1358,"end":1361},"obj":"GeneOrGeneProduct"},{"id":"T12","span":{"begin":1378,"end":1382},"obj":"GeneOrGeneProduct"},{"id":"T13","span":{"begin":1387,"end":1391},"obj":"GeneOrGeneProduct"},{"id":"T14","span":{"begin":1459,"end":1466},"obj":"GeneOrGeneProduct"},{"id":"T15","span":{"begin":1502,"end":1506},"obj":"GeneOrGeneProduct"},{"id":"T16","span":{"begin":1531,"end":1538},"obj":"GeneOrGeneProduct"},{"id":"T17","span":{"begin":1563,"end":1566},"obj":"GeneOrGeneProduct"},{"id":"T18","span":{"begin":1666,"end":1678},"obj":"GeneOrGeneProduct"},{"id":"T20","span":{"begin":1715,"end":1722},"obj":"GeneOrGeneProduct"},{"id":"T21","span":{"begin":1828,"end":1835},"obj":"GeneOrGeneProduct"},{"id":"T22","span":{"begin":1906,"end":1913},"obj":"GeneOrGeneProduct"},{"id":"T23","span":{"begin":1950,"end":1953},"obj":"GeneOrGeneProduct"},{"id":"T24","span":{"begin":2030,"end":2037},"obj":"GeneOrGeneProduct"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T2","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T3","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T4","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T5","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T6","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T7","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T8","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T9","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T10","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T11","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T12","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T13","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T14","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T15","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T16","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T17","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T18","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T20","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T21","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T22","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T23","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T24","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"}]},{"project":"LitCoin_Mondo_095","denotations":[{"id":"T1","span":{"begin":84,"end":107},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":288,"end":311},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":313,"end":317},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":2152,"end":2156},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A1","pred":"mondo_id","subj":"T1","obj":"0001046"},{"id":"A2","pred":"mondo_id","subj":"T2","obj":"0001046"},{"id":"A3","pred":"mondo_id","subj":"T3","obj":"0001046"},{"id":"A4","pred":"mondo_id","subj":"T4","obj":"0001046"},{"subj":"T1","pred":"source","obj":"LitCoin_Mondo_095"},{"subj":"T2","pred":"source","obj":"LitCoin_Mondo_095"},{"subj":"T3","pred":"source","obj":"LitCoin_Mondo_095"},{"subj":"T4","pred":"source","obj":"LitCoin_Mondo_095"}]},{"project":"LitCoin-MeSH-Disease-2","denotations":[{"id":"T1","span":{"begin":84,"end":107},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":254,"end":278},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":288,"end":311},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":313,"end":317},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T5","span":{"begin":921,"end":932},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T6","span":{"begin":1882,"end":1885},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T7","span":{"begin":2055,"end":2058},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T8","span":{"begin":2152,"end":2156},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A7","pred":"ID:","subj":"T7","obj":"DISEASE"},{"id":"A8","pred":"ID:","subj":"T8","obj":"D000071056"},{"id":"A2","pred":"ID:","subj":"T2","obj":"DISEASE"},{"id":"A5","pred":"ID:","subj":"T5","obj":"DISEASE"},{"id":"A3","pred":"ID:","subj":"T3","obj":"D000071056"},{"id":"A6","pred":"ID:","subj":"T6","obj":"DISEASE"},{"id":"A1","pred":"ID:","subj":"T1","obj":"D000071056"},{"id":"A4","pred":"ID:","subj":"T4","obj":"D000071056"},{"subj":"T1","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T2","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T3","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T4","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T5","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T6","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T7","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T8","pred":"source","obj":"LitCoin-MeSH-Disease-2"}]},{"project":"LitCoin-MONDO_bioort2019","denotations":[{"id":"T1","span":{"begin":84,"end":107},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":254,"end":278},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":288,"end":311},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":313,"end":317},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T5","span":{"begin":921,"end":932},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T6","span":{"begin":1882,"end":1885},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T7","span":{"begin":2055,"end":2058},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T8","span":{"begin":2152,"end":2156},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A4","pred":"#label","subj":"T4","obj":"D000071056"},{"id":"A3","pred":"#label","subj":"T3","obj":"D000071056"},{"id":"A1","pred":"#label","subj":"T1","obj":"D000071056"},{"id":"A7","pred":"#label","subj":"T7","obj":"DISEASE"},{"id":"A8","pred":"#label","subj":"T8","obj":"D000071056"},{"id":"A2","pred":"#label","subj":"T2","obj":"DISEASE"},{"id":"A6","pred":"#label","subj":"T6","obj":"DISEASE"},{"id":"A5","pred":"#label","subj":"T5","obj":"DISEASE"},{"subj":"T1","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T2","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T3","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T4","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T5","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T6","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T7","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T8","pred":"source","obj":"LitCoin-MONDO_bioort2019"}]},{"project":"LitCoin-Chemical-MeSH-CHEBI","denotations":[{"id":"T1","span":{"begin":752,"end":761},"obj":"ChemicalEntity"},{"id":"T3","span":{"begin":1227,"end":1250},"obj":"ChemicalEntity"}],"attributes":[{"id":"A1","pred":"ID:","subj":"T1","obj":"D013629"},{"id":"A2","pred":"ID:","subj":"T1","obj":"http://purl.obolibrary.org/obo/CHEBI_41774"},{"id":"A3","pred":"ID:","subj":"T3","obj":"D000943"},{"subj":"T1","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T3","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"}]},{"project":"LitCoin-NCBITaxon-2","denotations":[{"id":"T1","span":{"begin":39,"end":45},"obj":"OrganismTaxon"},{"id":"T2","span":{"begin":113,"end":119},"obj":"OrganismTaxon"},{"id":"T3","span":{"begin":2146,"end":2151},"obj":"OrganismTaxon"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCoin-NCBITaxon-2"},{"subj":"T2","pred":"source","obj":"LitCoin-NCBITaxon-2"},{"subj":"T3","pred":"source","obj":"LitCoin-NCBITaxon-2"}]},{"project":"LitCoin-training-merged","denotations":[{"id":"T3","span":{"begin":1227,"end":1250},"obj":"ChemicalEntity"},{"id":"T1","span":{"begin":752,"end":761},"obj":"ChemicalEntity"},{"id":"T24","span":{"begin":2030,"end":2037},"obj":"GeneOrGeneProduct"},{"id":"T23","span":{"begin":1950,"end":1953},"obj":"GeneOrGeneProduct"},{"id":"T22","span":{"begin":1906,"end":1913},"obj":"GeneOrGeneProduct"},{"id":"T21","span":{"begin":1828,"end":1835},"obj":"GeneOrGeneProduct"},{"id":"T20","span":{"begin":1715,"end":1722},"obj":"GeneOrGeneProduct"},{"id":"T18","span":{"begin":1666,"end":1678},"obj":"GeneOrGeneProduct"},{"id":"T17","span":{"begin":1563,"end":1566},"obj":"GeneOrGeneProduct"},{"id":"T16","span":{"begin":1531,"end":1538},"obj":"GeneOrGeneProduct"},{"id":"T15","span":{"begin":1502,"end":1506},"obj":"GeneOrGeneProduct"},{"id":"T14","span":{"begin":1459,"end":1466},"obj":"GeneOrGeneProduct"},{"id":"T13","span":{"begin":1387,"end":1391},"obj":"GeneOrGeneProduct"},{"id":"T12","span":{"begin":1378,"end":1382},"obj":"GeneOrGeneProduct"},{"id":"T11","span":{"begin":1358,"end":1361},"obj":"GeneOrGeneProduct"},{"id":"T10","span":{"begin":1330,"end":1356},"obj":"GeneOrGeneProduct"},{"id":"T9","span":{"begin":1274,"end":1283},"obj":"GeneOrGeneProduct"},{"id":"T8","span":{"begin":1260,"end":1269},"obj":"GeneOrGeneProduct"},{"id":"T7","span":{"begin":1052,"end":1059},"obj":"GeneOrGeneProduct"},{"id":"T6","span":{"begin":811,"end":818},"obj":"GeneOrGeneProduct"},{"id":"T5","span":{"begin":688,"end":695},"obj":"GeneOrGeneProduct"},{"id":"T4","span":{"begin":599,"end":606},"obj":"GeneOrGeneProduct"},{"id":"T79000","span":{"begin":420,"end":427},"obj":"GeneOrGeneProduct"},{"id":"T2","span":{"begin":201,"end":211},"obj":"GeneOrGeneProduct"},{"id":"T1674","span":{"begin":59,"end":66},"obj":"GeneOrGeneProduct"},{"id":"T99015","span":{"begin":2152,"end":2156},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T53676","span":{"begin":2055,"end":2058},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T35060","span":{"begin":1882,"end":1885},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T90754","span":{"begin":921,"end":932},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T78214","span":{"begin":313,"end":317},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T7978","span":{"begin":288,"end":311},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T44392","span":{"begin":254,"end":278},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T66265","span":{"begin":84,"end":107},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T64018","span":{"begin":2146,"end":2151},"obj":"OrganismTaxon"},{"id":"T40876","span":{"begin":113,"end":119},"obj":"OrganismTaxon"},{"id":"T75708","span":{"begin":39,"end":45},"obj":"OrganismTaxon"}],"attributes":[{"id":"A32284","pred":"#label","subj":"T66265","obj":"D000071056"},{"id":"A8","pred":"#label","subj":"T99015","obj":"D000071056"},{"id":"A2","pred":"ID:","subj":"T1","obj":"http://purl.obolibrary.org/obo/CHEBI_41774"},{"id":"A1","pred":"ID:","subj":"T1","obj":"D013629"},{"id":"A7","pred":"#label","subj":"T53676","obj":"DISEASE"},{"id":"A5","pred":"#label","subj":"T90754","obj":"DISEASE"},{"id":"A6","pred":"#label","subj":"T35060","obj":"DISEASE"},{"id":"A83457","pred":"#label","subj":"T7978","obj":"D000071056"},{"id":"A31701","pred":"#label","subj":"T44392","obj":"DISEASE"},{"id":"A3","pred":"ID:","subj":"T3","obj":"D000943"},{"id":"A4","pred":"#label","subj":"T78214","obj":"D000071056"},{"subj":"T3","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T1","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T24","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T23","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T22","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T21","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T20","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T18","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T17","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T16","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T15","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T14","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T13","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T12","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T11","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T10","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T9","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T8","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T7","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T6","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T5","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T4","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T79000","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T2","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T1674","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T99015","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T53676","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T35060","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T90754","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T78214","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T7978","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T44392","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T66265","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T64018","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T40876","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T75708","pred":"source","obj":"LitCoin-training-merged"}]},{"project":"PubmedHPO","denotations":[{"id":"T1","span":{"begin":288,"end":311},"obj":"HP_0012732"}],"attributes":[{"subj":"T1","pred":"source","obj":"PubmedHPO"}]},{"project":"Allie","denotations":[{"id":"SS1_24632946_1_0","span":{"begin":171,"end":187},"obj":"expanded"},{"id":"SS2_24632946_1_0","span":{"begin":189,"end":192},"obj":"abbr"},{"id":"SS1_24632946_2_0","span":{"begin":288,"end":311},"obj":"expanded"},{"id":"SS2_24632946_2_0","span":{"begin":313,"end":317},"obj":"abbr"},{"id":"SS1_24632946_5_0","span":{"begin":819,"end":845},"obj":"expanded"},{"id":"SS2_24632946_5_0","span":{"begin":847,"end":858},"obj":"abbr"},{"id":"SS1_24632946_9_0","span":{"begin":1330,"end":1356},"obj":"expanded"},{"id":"SS2_24632946_9_0","span":{"begin":1358,"end":1361},"obj":"abbr"}],"relations":[{"id":"AE1_24632946_1_0","pred":"abbreviatedTo","subj":"SS1_24632946_1_0","obj":"SS2_24632946_1_0"},{"id":"AE1_24632946_2_0","pred":"abbreviatedTo","subj":"SS1_24632946_2_0","obj":"SS2_24632946_2_0"},{"id":"AE1_24632946_5_0","pred":"abbreviatedTo","subj":"SS1_24632946_5_0","obj":"SS2_24632946_5_0"},{"id":"AE1_24632946_9_0","pred":"abbreviatedTo","subj":"SS1_24632946_9_0","obj":"SS2_24632946_9_0"}],"attributes":[{"subj":"SS1_24632946_1_0","pred":"source","obj":"Allie"},{"subj":"SS2_24632946_1_0","pred":"source","obj":"Allie"},{"subj":"SS1_24632946_2_0","pred":"source","obj":"Allie"},{"subj":"SS2_24632946_2_0","pred":"source","obj":"Allie"},{"subj":"SS1_24632946_5_0","pred":"source","obj":"Allie"},{"subj":"SS2_24632946_5_0","pred":"source","obj":"Allie"},{"subj":"SS1_24632946_9_0","pred":"source","obj":"Allie"},{"subj":"SS2_24632946_9_0","pred":"source","obj":"Allie"}]},{"project":"kaiyin_test","denotations":[{"id":"T4","span":{"begin":809,"end":818},"obj":"Protein"},{"id":"T34","span":{"begin":819,"end":823},"obj":"NegReg"},{"id":"T33","span":{"begin":829,"end":845},"obj":"PosReg"},{"id":"T3","span":{"begin":860,"end":867},"obj":"Var"},{"id":"T1","span":{"begin":887,"end":916},"obj":"CPA"},{"id":"T2","span":{"begin":921,"end":954},"obj":"CPA"},{"id":"T7","span":{"begin":960,"end":967},"obj":"Var"},{"id":"T5","span":{"begin":983,"end":990},"obj":"NegReg"},{"id":"T6","span":{"begin":991,"end":1031},"obj":"CPA"},{"id":"T10","span":{"begin":1050,"end":1059},"obj":"Protein"},{"id":"T11","span":{"begin":1064,"end":1071},"obj":"Var"},{"id":"T14","span":{"begin":1198,"end":1205},"obj":"NegReg"},{"id":"T15","span":{"begin":1206,"end":1223},"obj":"MPA"},{"id":"T35","span":{"begin":1260,"end":1269},"obj":"Protein"},{"id":"T36","span":{"begin":1274,"end":1283},"obj":"Protein"},{"id":"T16","span":{"begin":1316,"end":1326},"obj":"MPA"},{"id":"T18","span":{"begin":1330,"end":1368},"obj":"Gene"},{"id":"T37","span":{"begin":1378,"end":1382},"obj":"Gene"},{"id":"T38","span":{"begin":1387,"end":1391},"obj":"Gene"},{"id":"T19","span":{"begin":1414,"end":1421},"obj":"PosReg"},{"id":"T20","span":{"begin":1457,"end":1466},"obj":"Protein"},{"id":"T21","span":{"begin":1471,"end":1478},"obj":"Var"},{"id":"T22","span":{"begin":1484,"end":1494},"obj":"MPA"},{"id":"T23","span":{"begin":1502,"end":1511},"obj":"Gene"},{"id":"T26","span":{"begin":1551,"end":1576},"obj":"MPA"},{"id":"T25","span":{"begin":1587,"end":1596},"obj":"PosReg"},{"id":"T31","span":{"begin":1604,"end":1611},"obj":"Var"},{"id":"T39","span":{"begin":1882,"end":1885},"obj":"Disease"},{"id":"T40","span":{"begin":1904,"end":1913},"obj":"Protein"},{"id":"T41","span":{"begin":1914,"end":1917},"obj":"PosReg"},{"id":"T42","span":{"begin":1918,"end":1925},"obj":"Var"},{"id":"T43","span":{"begin":1931,"end":1940},"obj":"Reg"},{"id":"T29","span":{"begin":1950,"end":1963},"obj":"MPA"}],"relations":[{"id":"R1","pred":"ThemeOf","subj":"T4","obj":"T3"},{"id":"R12","pred":"ThemeOf","subj":"T15","obj":"T14"},{"id":"R15","pred":"CauseOf","subj":"T16","obj":"T19"},{"id":"R16","pred":"ThemeOf","subj":"T20","obj":"T21"},{"id":"R17","pred":"ThemeOf","subj":"T21","obj":"T19"},{"id":"R18","pred":"ThemeOf","subj":"T23","obj":"T22"},{"id":"R20","pred":"ThemeOf","subj":"T22","obj":"T25"},{"id":"R21","pred":"ThemeOf","subj":"T26","obj":"T25"},{"id":"R22","pred":"CauseOf","subj":"T31","obj":"T25"},{"id":"R25","pred":"CauseOf","subj":"T3","obj":"T33"},{"id":"R26","pred":"CauseOf","subj":"T3","obj":"T34"},{"id":"R27","pred":"ThemeOf","subj":"T1","obj":"T34"},{"id":"R28","pred":"ThemeOf","subj":"T2","obj":"T33"},{"id":"R29","pred":"CauseOf","subj":"T2","obj":"T34"},{"id":"R30","pred":"CauseOf","subj":"T1","obj":"T33"},{"id":"R31","pred":"ThemeOf","subj":"T35","obj":"T15"},{"id":"R32","pred":"ThemeOf","subj":"T36","obj":"T15"},{"id":"R33","pred":"CauseOf","subj":"T11","obj":"T14"},{"id":"R34","pred":"ThemeOf","subj":"T18","obj":"T16"},{"id":"R35","pred":"ThemeOf","subj":"T37","obj":"T18"},{"id":"R36","pred":"ThemeOf","subj":"T38","obj":"T18"},{"id":"R37","pred":"ThemeOf","subj":"T39","obj":"T41"},{"id":"R38","pred":"CauseOf","subj":"T42","obj":"T43"},{"id":"R39","pred":"ThemeOf","subj":"T29","obj":"T43"},{"id":"R4","pred":"CauseOf","subj":"T7","obj":"T5"},{"id":"R40","pred":"ThemeOf","subj":"T40","obj":"T42"},{"id":"R41","pred":"CauseOf","subj":"T43","obj":"T41"},{"id":"R5","pred":"ThemeOf","subj":"T6","obj":"T5"},{"id":"R6","pred":"ThemeOf","subj":"T10","obj":"T11"}],"attributes":[{"subj":"T4","pred":"source","obj":"kaiyin_test"},{"subj":"T34","pred":"source","obj":"kaiyin_test"},{"subj":"T33","pred":"source","obj":"kaiyin_test"},{"subj":"T3","pred":"source","obj":"kaiyin_test"},{"subj":"T1","pred":"source","obj":"kaiyin_test"},{"subj":"T2","pred":"source","obj":"kaiyin_test"},{"subj":"T7","pred":"source","obj":"kaiyin_test"},{"subj":"T5","pred":"source","obj":"kaiyin_test"},{"subj":"T6","pred":"source","obj":"kaiyin_test"},{"subj":"T10","pred":"source","obj":"kaiyin_test"},{"subj":"T11","pred":"source","obj":"kaiyin_test"},{"subj":"T14","pred":"source","obj":"kaiyin_test"},{"subj":"T15","pred":"source","obj":"kaiyin_test"},{"subj":"T35","pred":"source","obj":"kaiyin_test"},{"subj":"T36","pred":"source","obj":"kaiyin_test"},{"subj":"T16","pred":"source","obj":"kaiyin_test"},{"subj":"T18","pred":"source","obj":"kaiyin_test"},{"subj":"T37","pred":"source","obj":"kaiyin_test"},{"subj":"T38","pred":"source","obj":"kaiyin_test"},{"subj":"T19","pred":"source","obj":"kaiyin_test"},{"subj":"T20","pred":"source","obj":"kaiyin_test"},{"subj":"T21","pred":"source","obj":"kaiyin_test"},{"subj":"T22","pred":"source","obj":"kaiyin_test"},{"subj":"T23","pred":"source","obj":"kaiyin_test"},{"subj":"T26","pred":"source","obj":"kaiyin_test"},{"subj":"T25","pred":"source","obj":"kaiyin_test"},{"subj":"T31","pred":"source","obj":"kaiyin_test"},{"subj":"T39","pred":"source","obj":"kaiyin_test"},{"subj":"T40","pred":"source","obj":"kaiyin_test"},{"subj":"T41","pred":"source","obj":"kaiyin_test"},{"subj":"T42","pred":"source","obj":"kaiyin_test"},{"subj":"T43","pred":"source","obj":"kaiyin_test"},{"subj":"T29","pred":"source","obj":"kaiyin_test"}]},{"project":"name_no","denotations":[{"id":"T4","span":{"begin":809,"end":818},"obj":"Protein"},{"id":"T34","span":{"begin":819,"end":823},"obj":"NegReg"},{"id":"T33","span":{"begin":829,"end":845},"obj":"PosReg"},{"id":"T3","span":{"begin":860,"end":867},"obj":"Var"},{"id":"T1","span":{"begin":887,"end":916},"obj":"CPA"},{"id":"T2","span":{"begin":921,"end":954},"obj":"CPA"},{"id":"T7","span":{"begin":960,"end":967},"obj":"Var"},{"id":"T5","span":{"begin":983,"end":990},"obj":"NegReg"},{"id":"T6","span":{"begin":991,"end":1031},"obj":"CPA"},{"id":"T10","span":{"begin":1050,"end":1059},"obj":"Protein"},{"id":"T11","span":{"begin":1064,"end":1071},"obj":"Var"},{"id":"T14","span":{"begin":1198,"end":1205},"obj":"NegReg"},{"id":"T15","span":{"begin":1206,"end":1223},"obj":"MPA"},{"id":"T35","span":{"begin":1260,"end":1269},"obj":"Protein"},{"id":"T36","span":{"begin":1274,"end":1283},"obj":"Protein"},{"id":"T16","span":{"begin":1316,"end":1326},"obj":"MPA"},{"id":"T18","span":{"begin":1330,"end":1368},"obj":"Gene"},{"id":"T37","span":{"begin":1378,"end":1382},"obj":"Gene"},{"id":"T38","span":{"begin":1387,"end":1391},"obj":"Gene"},{"id":"T19","span":{"begin":1414,"end":1421},"obj":"PosReg"},{"id":"T20","span":{"begin":1457,"end":1466},"obj":"Protein"},{"id":"T21","span":{"begin":1471,"end":1478},"obj":"Var"},{"id":"T22","span":{"begin":1484,"end":1494},"obj":"MPA"},{"id":"T23","span":{"begin":1502,"end":1511},"obj":"Gene"},{"id":"T26","span":{"begin":1551,"end":1576},"obj":"MPA"},{"id":"T25","span":{"begin":1587,"end":1596},"obj":"PosReg"},{"id":"T31","span":{"begin":1604,"end":1611},"obj":"Var"},{"id":"T39","span":{"begin":1882,"end":1885},"obj":"Disease"},{"id":"T40","span":{"begin":1904,"end":1913},"obj":"Protein"},{"id":"T41","span":{"begin":1914,"end":1917},"obj":"PosReg"},{"id":"T42","span":{"begin":1918,"end":1925},"obj":"Var"},{"id":"T43","span":{"begin":1931,"end":1940},"obj":"Reg"},{"id":"T29","span":{"begin":1950,"end":1963},"obj":"MPA"}],"relations":[{"id":"R1","pred":"ThemeOf","subj":"T4","obj":"T3"},{"id":"R12","pred":"ThemeOf","subj":"T15","obj":"T14"},{"id":"R15","pred":"CauseOf","subj":"T16","obj":"T19"},{"id":"R16","pred":"ThemeOf","subj":"T20","obj":"T21"},{"id":"R17","pred":"ThemeOf","subj":"T21","obj":"T19"},{"id":"R18","pred":"ThemeOf","subj":"T23","obj":"T22"},{"id":"R20","pred":"ThemeOf","subj":"T22","obj":"T25"},{"id":"R21","pred":"ThemeOf","subj":"T26","obj":"T25"},{"id":"R22","pred":"CauseOf","subj":"T31","obj":"T25"},{"id":"R25","pred":"CauseOf","subj":"T3","obj":"T33"},{"id":"R26","pred":"CauseOf","subj":"T3","obj":"T34"},{"id":"R27","pred":"ThemeOf","subj":"T1","obj":"T34"},{"id":"R28","pred":"ThemeOf","subj":"T2","obj":"T33"},{"id":"R29","pred":"CauseOf","subj":"T2","obj":"T34"},{"id":"R30","pred":"CauseOf","subj":"T1","obj":"T33"},{"id":"R31","pred":"ThemeOf","subj":"T35","obj":"T15"},{"id":"R32","pred":"ThemeOf","subj":"T36","obj":"T15"},{"id":"R33","pred":"CauseOf","subj":"T11","obj":"T14"},{"id":"R34","pred":"ThemeOf","subj":"T18","obj":"T16"},{"id":"R35","pred":"ThemeOf","subj":"T37","obj":"T18"},{"id":"R36","pred":"ThemeOf","subj":"T38","obj":"T18"},{"id":"R37","pred":"ThemeOf","subj":"T39","obj":"T41"},{"id":"R38","pred":"CauseOf","subj":"T42","obj":"T43"},{"id":"R39","pred":"ThemeOf","subj":"T29","obj":"T43"},{"id":"R4","pred":"CauseOf","subj":"T7","obj":"T5"},{"id":"R40","pred":"ThemeOf","subj":"T40","obj":"T42"},{"id":"R41","pred":"CauseOf","subj":"T43","obj":"T41"},{"id":"R5","pred":"ThemeOf","subj":"T6","obj":"T5"},{"id":"R6","pred":"ThemeOf","subj":"T10","obj":"T11"}],"attributes":[{"subj":"T4","pred":"source","obj":"name_no"},{"subj":"T34","pred":"source","obj":"name_no"},{"subj":"T33","pred":"source","obj":"name_no"},{"subj":"T3","pred":"source","obj":"name_no"},{"subj":"T1","pred":"source","obj":"name_no"},{"subj":"T2","pred":"source","obj":"name_no"},{"subj":"T7","pred":"source","obj":"name_no"},{"subj":"T5","pred":"source","obj":"name_no"},{"subj":"T6","pred":"source","obj":"name_no"},{"subj":"T10","pred":"source","obj":"name_no"},{"subj":"T11","pred":"source","obj":"name_no"},{"subj":"T14","pred":"source","obj":"name_no"},{"subj":"T15","pred":"source","obj":"name_no"},{"subj":"T35","pred":"source","obj":"name_no"},{"subj":"T36","pred":"source","obj":"name_no"},{"subj":"T16","pred":"source","obj":"name_no"},{"subj":"T18","pred":"source","obj":"name_no"},{"subj":"T37","pred":"source","obj":"name_no"},{"subj":"T38","pred":"source","obj":"name_no"},{"subj":"T19","pred":"source","obj":"name_no"},{"subj":"T20","pred":"source","obj":"name_no"},{"subj":"T21","pred":"source","obj":"name_no"},{"subj":"T22","pred":"source","obj":"name_no"},{"subj":"T23","pred":"source","obj":"name_no"},{"subj":"T26","pred":"source","obj":"name_no"},{"subj":"T25","pred":"source","obj":"name_no"},{"subj":"T31","pred":"source","obj":"name_no"},{"subj":"T39","pred":"source","obj":"name_no"},{"subj":"T40","pred":"source","obj":"name_no"},{"subj":"T41","pred":"source","obj":"name_no"},{"subj":"T42","pred":"source","obj":"name_no"},{"subj":"T43","pred":"source","obj":"name_no"},{"subj":"T29","pred":"source","obj":"name_no"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"sonoma2","color":"#93ecdf","default":true},{"id":"LitCoin-entities","color":"#ecc593"},{"id":"LitCoin-entities-OrganismTaxon-PD","color":"#ab93ec"},{"id":"LitCoin-sentences","color":"#95ec93"},{"id":"LitCoin_Mondo","color":"#ec93af"},{"id":"LitCoin-GeneOrGeneProduct-v0","color":"#93c9ec"},{"id":"LitCoin-GeneOrGeneProduct-v2","color":"#e3ec93"},{"id":"LitCoin-Disease-MeSH","color":"#db93ec"},{"id":"LitCoin-GeneOrGeneProduct-v3","color":"#93ecc1"},{"id":"LitCoin_Mondo_095","color":"#eca793"},{"id":"LitCoin-MeSH-Disease-2","color":"#9398ec"},{"id":"LitCoin-MONDO_bioort2019","color":"#b2ec93"},{"id":"LitCoin-Chemical-MeSH-CHEBI","color":"#ec93cc"},{"id":"LitCoin-NCBITaxon-2","color":"#93e6ec"},{"id":"LitCoin-training-merged","color":"#ecd793"},{"id":"PubmedHPO","color":"#bd93ec"},{"id":"Allie","color":"#93eca3"},{"id":"kaiyin_test","color":"#ec939c"},{"id":"name_no","color":"#93b6ec"}]}]}}