PubMed:24581344 / 739-1135 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/24581344","sourcedb":"PubMed","sourceid":"24581344","source_url":"https://www.ncbi.nlm.nih.gov/pubmed/24581344","text":"A \"top-down\" approach was used to characterize changes in VIC phenotype in response to collagen alterations in the native 3D environment. Collagen-deficient leaflets were created via enzymatic treatment and cultured statically for six days in vitro. After culture, leaflets were harvested for analysis of DNA, proliferation, apoptosis, ECM composition, calcification, and gene/protein expression.","tracks":[{"project":"PubMed_Structured_Abstracts","denotations":[{"id":"T2","span":{"begin":0,"end":396},"obj":"METHODS"}],"attributes":[{"subj":"T2","pred":"source","obj":"PubMed_Structured_Abstracts"}]},{"project":"Goldhamster2_Cellosaurus","denotations":[{"id":"T4","span":{"begin":0,"end":1},"obj":"CVCL_6479|Finite_cell_line|Mus musculus"},{"id":"T5","span":{"begin":47,"end":54},"obj":"CVCL_0238|Cancer_cell_line|Homo sapiens"}],"attributes":[{"subj":"T4","pred":"source","obj":"Goldhamster2_Cellosaurus"},{"subj":"T5","pred":"source","obj":"Goldhamster2_Cellosaurus"}]},{"project":"GoldHamster","denotations":[{"id":"T45","span":{"begin":58,"end":61},"obj":"PR:000006898"},{"id":"T46","span":{"begin":58,"end":61},"obj":"P23943"},{"id":"T47","span":{"begin":58,"end":61},"obj":"P22389"},{"id":"T49","span":{"begin":87,"end":95},"obj":"2714"},{"id":"T50","span":{"begin":87,"end":95},"obj":"D003094"},{"id":"T51","span":{"begin":87,"end":95},"obj":"CHEBI:3815"},{"id":"T48","span":{"begin":87,"end":95},"obj":"GO:0005202"},{"id":"T53","span":{"begin":138,"end":146},"obj":"2714"},{"id":"T54","span":{"begin":138,"end":146},"obj":"D003094"},{"id":"T55","span":{"begin":138,"end":146},"obj":"CHEBI:3815"},{"id":"T52","span":{"begin":138,"end":146},"obj":"GO:0005202"},{"id":"T56","span":{"begin":183,"end":192},"obj":"SO:0001185"},{"id":"T59","span":{"begin":305,"end":308},"obj":"SO:0000352"},{"id":"T57","span":{"begin":305,"end":308},"obj":"GO:0005574"},{"id":"T58","span":{"begin":305,"end":308},"obj":"CHEBI:16991"},{"id":"T60","span":{"begin":305,"end":308},"obj":"D004247"},{"id":"T61","span":{"begin":310,"end":323},"obj":"UBERON:2000098"},{"id":"T62","span":{"begin":325,"end":334},"obj":"GO:0097194"},{"id":"T63","span":{"begin":325,"end":334},"obj":"GO:0006915"},{"id":"T64","span":{"begin":336,"end":339},"obj":"PR:Q13201"},{"id":"T66","span":{"begin":336,"end":339},"obj":"PR:000010492"},{"id":"T65","span":{"begin":336,"end":339},"obj":"UBERON:4000022"},{"id":"T67","span":{"begin":372,"end":376},"obj":"SO:0000704"},{"id":"T72","span":{"begin":377,"end":384},"obj":"SO:0000104"},{"id":"T71","span":{"begin":377,"end":384},"obj":"PR:000000001"},{"id":"T68","span":{"begin":377,"end":384},"obj":"GO:0003675"},{"id":"T69","span":{"begin":377,"end":384},"obj":"CHEBI:36080"},{"id":"T70","span":{"begin":377,"end":384},"obj":"CHEBI:11122"}],"attributes":[{"subj":"T45","pred":"source","obj":"GoldHamster"},{"subj":"T46","pred":"source","obj":"GoldHamster"},{"subj":"T47","pred":"source","obj":"GoldHamster"},{"subj":"T49","pred":"source","obj":"GoldHamster"},{"subj":"T50","pred":"source","obj":"GoldHamster"},{"subj":"T51","pred":"source","obj":"GoldHamster"},{"subj":"T48","pred":"source","obj":"GoldHamster"},{"subj":"T53","pred":"source","obj":"GoldHamster"},{"subj":"T54","pred":"source","obj":"GoldHamster"},{"subj":"T55","pred":"source","obj":"GoldHamster"},{"subj":"T52","pred":"source","obj":"GoldHamster"},{"subj":"T56","pred":"source","obj":"GoldHamster"},{"subj":"T59","pred":"source","obj":"GoldHamster"},{"subj":"T57","pred":"source","obj":"GoldHamster"},{"subj":"T58","pred":"source","obj":"GoldHamster"},{"subj":"T60","pred":"source","obj":"GoldHamster"},{"subj":"T61","pred":"source","obj":"GoldHamster"},{"subj":"T62","pred":"source","obj":"GoldHamster"},{"subj":"T63","pred":"source","obj":"GoldHamster"},{"subj":"T64","pred":"source","obj":"GoldHamster"},{"subj":"T66","pred":"source","obj":"GoldHamster"},{"subj":"T65","pred":"source","obj":"GoldHamster"},{"subj":"T67","pred":"source","obj":"GoldHamster"},{"subj":"T72","pred":"source","obj":"GoldHamster"},{"subj":"T71","pred":"source","obj":"GoldHamster"},{"subj":"T68","pred":"source","obj":"GoldHamster"},{"subj":"T69","pred":"source","obj":"GoldHamster"},{"subj":"T70","pred":"source","obj":"GoldHamster"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"PubMed_Structured_Abstracts","color":"#93d9ec","default":true},{"id":"Goldhamster2_Cellosaurus","color":"#ece593"},{"id":"GoldHamster","color":"#cb93ec"}]}]}}