PubMed:24486742
Annnotations
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TextSentencer_T1 | 0-108 | Sentence | denotes | miRNA423-5p regulates cell proliferation and invasion by targeting trefoil factor 1 in gastric cancer cells. |
| TextSentencer_T2 | 109-298 | Sentence | denotes | TFF1 is a small, secreted protein in the TFF family that has a pivotal role as a motogenic factor in epithelial restitution and cell motility, and as a tumor suppressor gene in the stomach. |
| TextSentencer_T3 | 299-567 | Sentence | denotes | In this study, we identified TFF1 as a novel target gene of miRNA-423-5p. miRNA-423-5p negatively regulated the expression of TFF1 by binding to its 3'UTR and participated in proliferation/invasion-related processes via a TFF1-dependent manner in gastric cancer cells. |
| TextSentencer_T4 | 568-713 | Sentence | denotes | Our findings suggested that miR-423-5p may be a novel target for the future development of specific therapeutic interventions for gastric cancer. |
| T1 | 0-108 | Sentence | denotes | miRNA423-5p regulates cell proliferation and invasion by targeting trefoil factor 1 in gastric cancer cells. |
| T2 | 109-298 | Sentence | denotes | TFF1 is a small, secreted protein in the TFF family that has a pivotal role as a motogenic factor in epithelial restitution and cell motility, and as a tumor suppressor gene in the stomach. |
| T3 | 299-567 | Sentence | denotes | In this study, we identified TFF1 as a novel target gene of miRNA-423-5p. miRNA-423-5p negatively regulated the expression of TFF1 by binding to its 3'UTR and participated in proliferation/invasion-related processes via a TFF1-dependent manner in gastric cancer cells. |
| T4 | 568-713 | Sentence | denotes | Our findings suggested that miR-423-5p may be a novel target for the future development of specific therapeutic interventions for gastric cancer. |
DisGeNET
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T0 | 67-83 | gene:7031 | denotes | trefoil factor 1 |
| T1 | 87-101 | disease:C0699791 | denotes | gastric cancer |
| T2 | 67-83 | gene:7031 | denotes | trefoil factor 1 |
| T3 | 87-101 | disease:C0024623 | denotes | gastric cancer |
| T4 | 425-429 | gene:7031 | denotes | TFF1 |
| T5 | 546-560 | disease:C0024623 | denotes | gastric cancer |
| T6 | 425-429 | gene:7031 | denotes | TFF1 |
| T7 | 546-560 | disease:C0699791 | denotes | gastric cancer |
| T8 | 596-603 | gene:494335 | denotes | miR-423 |
| T9 | 698-712 | disease:C0699791 | denotes | gastric cancer |
| T10 | 596-603 | gene:494335 | denotes | miR-423 |
| T11 | 698-712 | disease:C0024623 | denotes | gastric cancer |
| R1 | T0 | T1 | associated_with | trefoil factor 1,gastric cancer |
| R2 | T2 | T3 | associated_with | trefoil factor 1,gastric cancer |
| R3 | T4 | T5 | associated_with | TFF1,gastric cancer |
| R4 | T6 | T7 | associated_with | TFF1,gastric cancer |
| R5 | T8 | T9 | associated_with | miR-423,gastric cancer |
| R6 | T10 | T11 | associated_with | miR-423,gastric cancer |
PubmedHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 261-266 | HP_0002664 | denotes | tumor |
| T2 | 546-560 | HP_0012126 | denotes | gastric cancer |
| T3 | 554-560 | HP_0002664 | denotes | cancer |
| T4 | 698-712 | HP_0012126 | denotes | gastric cancer |
| T5 | 706-712 | HP_0002664 | denotes | cancer |
DisGeNET5_gene_disease
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 24486742-0#67#83#gene7031 | 67-83 | gene7031 | denotes | trefoil factor 1 |
| 24486742-0#87#101#diseaseC0024623 | 87-101 | diseaseC0024623 | denotes | gastric cancer |
| 24486742-0#87#101#diseaseC0699791 | 87-101 | diseaseC0699791 | denotes | gastric cancer |
| 24486742-3#28#35#gene494335 | 596-603 | gene494335 | denotes | miR-423 |
| 24486742-3#130#144#diseaseC0024623 | 698-712 | diseaseC0024623 | denotes | gastric cancer |
| 24486742-3#130#144#diseaseC0699791 | 698-712 | diseaseC0699791 | denotes | gastric cancer |
| 67#83#gene703187#101#diseaseC0024623 | 24486742-0#67#83#gene7031 | 24486742-0#87#101#diseaseC0024623 | associated_with | trefoil factor 1,gastric cancer |
| 67#83#gene703187#101#diseaseC0699791 | 24486742-0#67#83#gene7031 | 24486742-0#87#101#diseaseC0699791 | associated_with | trefoil factor 1,gastric cancer |
| 28#35#gene494335130#144#diseaseC0024623 | 24486742-3#28#35#gene494335 | 24486742-3#130#144#diseaseC0024623 | associated_with | miR-423,gastric cancer |
| 28#35#gene494335130#144#diseaseC0699791 | 24486742-3#28#35#gene494335 | 24486742-3#130#144#diseaseC0699791 | associated_with | miR-423,gastric cancer |
DisGeNet-2017-sample
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T2116 | 596-603 | gene:494335 | denotes | miR-423 |
| T2117 | 698-712 | disease:C0024623 | denotes | gastric cancer |
| R1 | T2116 | T2117 | associated_with | miR-423,gastric cancer |
| R2 | T2116 | T2117 | associated_with | miR-423,gastric cancer |
UBERON-AE
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-UBERON-AE-B_T1 | 290-297 | http://purl.obolibrary.org/obo/UBERON_0000945 | denotes | stomach |
performance-test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-UBERON-AE-B_T1 | 290-297 | http://purl.obolibrary.org/obo/UBERON_0000945 | denotes | stomach |