PubMed:23952588
Annnotations
LitCoin-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T12 | 728-772 | Sentence | denotes | The median disease duration was 6 (7) years. |
T13 | 773-852 | Sentence | denotes | Dyskinesia was present in 44% (n = 42) with median levodopa therapy of 3 years. |
T14 | 853-932 | Sentence | denotes | There were 64.3% Chinese, 31% Malays, and 3.7% Indians and other ethnic groups. |
T15 | 933-1006 | Sentence | denotes | Eighty-one percent of patients with dyskinesia had clinical fluctuations. |
T16 | 1007-1277 | Sentence | denotes | Patients with dyskinesia had lower onset age ( p < 0.001), longer duration of levodopa therapy ( p < 0.001), longer disease duration ( p < 0.001), higher total daily levodopa dose ( p < 0.001), and higher total UPDRS scores ( p = 0.005) than patients without dyskinesia. |
T17 | 1278-1401 | Sentence | denotes | The three significant predictors of dyskinesia were duration of levodopa therapy, onset age, and total daily levodopa dose. |
T18 | 1402-1414 | Sentence | denotes | CONCLUSIONS: |
T4 | 253-370 | Sentence | denotes | We studied the prevalence and predictors of levodopa-induced dyskinesia among multiethnic Malaysian patients with PD. |
T5 | 371-379 | Sentence | denotes | METHODS: |
T6 | 380-498 | Sentence | denotes | This is a cross-sectional study involving 95 patients with PD on uninterrupted levodopa therapy for at least 6 months. |
T7 | 499-548 | Sentence | denotes | The instrument used was the UPDRS questionnaires. |
T8 | 549-642 | Sentence | denotes | The predictors of dyskinesia were determined using multivariate logistic regression analysis. |
T9 | 643-651 | Sentence | denotes | RESULTS: |
T10 | 652-686 | Sentence | denotes | The mean age was 65.6 ± 8.5 years. |
T11 | 687-727 | Sentence | denotes | The mean onset age was 58.5 ± 9.8 years. |
T1 | 0-113 | Sentence | denotes | Risk factors and predictors of levodopa-induced dyskinesia among multiethnic Malaysians with Parkinson's disease. |
T2 | 114-125 | Sentence | denotes | UNLABELLED: |
T3 | 126-252 | Sentence | denotes | Chronic pulsatile levodopa therapy for Parkinson's disease (PD) leads to the development of motor fluctuations and dyskinesia. |
T19 | 1415-1485 | Sentence | denotes | The prevalence of levodopa-induced dyskinesia in our patients was 44%. |
T20 | 1486-1594 | Sentence | denotes | The most significant predictors were duration of levodopa therapy, total daily levodopa dose, and onset age. |
LitCoin-entities
Id | Subject | Object | Predicate | Lexical cue | db_id |
---|---|---|---|---|---|
9323 | 31-39 | ChemicalEntity | denotes | levodopa | MESH:D007980 |
9324 | 48-58 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | MESH:D004409 |
9325 | 93-112 | DiseaseOrPhenotypicFeature | denotes | Parkinson's disease | MESH:D010300 |
9326 | 144-152 | ChemicalEntity | denotes | levodopa | MESH:D007980 |
9327 | 165-184 | DiseaseOrPhenotypicFeature | denotes | Parkinson's disease | MESH:D010300 |
9328 | 186-188 | DiseaseOrPhenotypicFeature | denotes | PD | MESH:D010300 |
9329 | 241-251 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | MESH:D004409 |
9330 | 297-305 | ChemicalEntity | denotes | levodopa | MESH:D007980 |
9331 | 314-324 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | MESH:D004409 |
9332 | 353-361 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
9333 | 367-369 | DiseaseOrPhenotypicFeature | denotes | PD | MESH:D010300 |
9334 | 425-433 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
9335 | 439-441 | DiseaseOrPhenotypicFeature | denotes | PD | MESH:D010300 |
9336 | 459-467 | ChemicalEntity | denotes | levodopa | MESH:D007980 |
9337 | 567-577 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | MESH:D004409 |
9338 | 773-783 | DiseaseOrPhenotypicFeature | denotes | Dyskinesia | MESH:D004409 |
9339 | 824-832 | ChemicalEntity | denotes | levodopa | MESH:D007980 |
9340 | 955-963 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
9341 | 969-979 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | MESH:D004409 |
9342 | 1007-1015 | OrganismTaxon | denotes | Patients | NCBITaxon:9606 |
9343 | 1021-1031 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | MESH:D004409 |
9344 | 1085-1093 | ChemicalEntity | denotes | levodopa | MESH:D007980 |
9345 | 1173-1181 | ChemicalEntity | denotes | levodopa | MESH:D007980 |
9346 | 1249-1257 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
9347 | 1266-1276 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | MESH:D004409 |
9348 | 1314-1324 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | MESH:D004409 |
9349 | 1342-1350 | ChemicalEntity | denotes | levodopa | MESH:D007980 |
9350 | 1387-1395 | ChemicalEntity | denotes | levodopa | MESH:D007980 |
9351 | 1433-1441 | ChemicalEntity | denotes | levodopa | MESH:D007980 |
9352 | 1450-1460 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | MESH:D004409 |
9353 | 1468-1476 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
9354 | 1535-1543 | ChemicalEntity | denotes | levodopa | MESH:D007980 |
9355 | 1565-1573 | ChemicalEntity | denotes | levodopa | MESH:D007980 |
LitCoin_Mondo
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T1 | 93-112 | DiseaseOrPhenotypicFeature | denotes | Parkinson's disease | 0005180 |
T2 | 165-184 | DiseaseOrPhenotypicFeature | denotes | Parkinson's disease | 0005180 |
LitCoin-GeneOrGeneProduct-v0
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 5-12 | GeneOrGeneProduct | denotes | factors |
T2 | 40-47 | GeneOrGeneProduct | denotes | induced |
T3 | 218-223 | GeneOrGeneProduct | denotes | motor |
T4 | 306-313 | GeneOrGeneProduct | denotes | induced |
T5 | 371-378 | GeneOrGeneProduct | denotes | METHODS |
T6 | 583-593 | GeneOrGeneProduct | denotes | determined |
T7 | 680-685 | GeneOrGeneProduct | denotes | years |
T8 | 721-726 | GeneOrGeneProduct | denotes | years |
T9 | 766-771 | GeneOrGeneProduct | denotes | years |
T10 | 846-851 | GeneOrGeneProduct | denotes | years |
T11 | 912-917 | GeneOrGeneProduct | denotes | other |
T12 | 1161-1166 | GeneOrGeneProduct | denotes | total |
T13 | 1212-1217 | GeneOrGeneProduct | denotes | total |
T14 | 1375-1380 | GeneOrGeneProduct | denotes | total |
T15 | 1442-1449 | GeneOrGeneProduct | denotes | induced |
T16 | 1553-1558 | GeneOrGeneProduct | denotes | total |
LitCoin-GeneOrGeneProduct-v2
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 218-223 | GeneOrGeneProduct | denotes | motor |
T2 | 912-917 | GeneOrGeneProduct | denotes | other |
LitCoin-Disease-MeSH
Id | Subject | Object | Predicate | Lexical cue | originalLabel |
---|---|---|---|---|---|
T1 | 48-58 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | D020820 |
T2 | 93-112 | DiseaseOrPhenotypicFeature | denotes | Parkinson's disease | D010300 |
T3 | 165-184 | DiseaseOrPhenotypicFeature | denotes | Parkinson's disease | D010300 |
T4 | 186-188 | DiseaseOrPhenotypicFeature | denotes | PD | D010300 |
T5 | 241-251 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | D020820 |
T6 | 314-324 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | D020820 |
T7 | 367-369 | DiseaseOrPhenotypicFeature | denotes | PD | D010300 |
T8 | 439-441 | DiseaseOrPhenotypicFeature | denotes | PD | D010300 |
T9 | 567-577 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | D020820 |
T10 | 739-746 | DiseaseOrPhenotypicFeature | denotes | disease | D004194 |
T11 | 773-783 | DiseaseOrPhenotypicFeature | denotes | Dyskinesia | D020820 |
T12 | 969-979 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | D020820 |
T13 | 1021-1031 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | D020820 |
T14 | 1123-1130 | DiseaseOrPhenotypicFeature | denotes | disease | D004194 |
T15 | 1266-1276 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | D020820 |
T16 | 1314-1324 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | D020820 |
T17 | 1450-1460 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | D020820 |
LitCoin_Mondo_095
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T1 | 93-112 | DiseaseOrPhenotypicFeature | denotes | Parkinson's disease | 0005180 |
T2 | 165-184 | DiseaseOrPhenotypicFeature | denotes | Parkinson's disease | 0005180 |
T3 | 186-188 | DiseaseOrPhenotypicFeature | denotes | PD | 0015873|0008199|0005180 |
T6 | 367-369 | DiseaseOrPhenotypicFeature | denotes | PD | 0015873|0008199|0005180 |
T9 | 439-441 | DiseaseOrPhenotypicFeature | denotes | PD | 0015873|0008199|0005180 |
LitCoin-MeSH-Disease-2
Id | Subject | Object | Predicate | Lexical cue | ID: |
---|---|---|---|---|---|
T1 | 48-58 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | D020820 |
T2 | 93-112 | DiseaseOrPhenotypicFeature | denotes | Parkinson's disease | D010300 |
T3 | 165-184 | DiseaseOrPhenotypicFeature | denotes | Parkinson's disease | D010300 |
T4 | 186-188 | DiseaseOrPhenotypicFeature | denotes | PD | D010300 |
T5 | 241-251 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | D020820 |
T6 | 314-324 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | D020820 |
T7 | 367-369 | DiseaseOrPhenotypicFeature | denotes | PD | D010300 |
T8 | 439-441 | DiseaseOrPhenotypicFeature | denotes | PD | D010300 |
T9 | 567-577 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | D020820 |
T10 | 739-746 | DiseaseOrPhenotypicFeature | denotes | disease | D004194 |
T11 | 773-783 | DiseaseOrPhenotypicFeature | denotes | Dyskinesia | D020820 |
T12 | 969-979 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | D020820 |
T13 | 1021-1031 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | D020820 |
T14 | 1123-1130 | DiseaseOrPhenotypicFeature | denotes | disease | D004194 |
T15 | 1266-1276 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | D020820 |
T16 | 1314-1324 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | D020820 |
T17 | 1450-1460 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | D020820 |
LitCoin-MONDO_bioort2019
Id | Subject | Object | Predicate | Lexical cue | #label |
---|---|---|---|---|---|
T1 | 48-58 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | D020820 |
T2 | 93-112 | DiseaseOrPhenotypicFeature | denotes | Parkinson's disease | D010300 |
T3 | 165-184 | DiseaseOrPhenotypicFeature | denotes | Parkinson's disease | D010300 |
T4 | 186-188 | DiseaseOrPhenotypicFeature | denotes | PD | D010300 |
T5 | 241-251 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | D020820 |
T6 | 314-324 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | D020820 |
T7 | 367-369 | DiseaseOrPhenotypicFeature | denotes | PD | D010300 |
T8 | 439-441 | DiseaseOrPhenotypicFeature | denotes | PD | D010300 |
T9 | 567-577 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | D020820 |
T10 | 773-783 | DiseaseOrPhenotypicFeature | denotes | Dyskinesia | D020820 |
T11 | 969-979 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | D020820 |
T12 | 1021-1031 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | D020820 |
T13 | 1266-1276 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | D020820 |
T14 | 1314-1324 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | D020820 |
T15 | 1450-1460 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | D020820 |
LitCoin-Chemical-MeSH-CHEBI
Id | Subject | Object | Predicate | Lexical cue | ID: |
---|---|---|---|---|---|
T1 | 31-39 | ChemicalEntity | denotes | levodopa | http://purl.obolibrary.org/obo/CHEBI_15765 |
T2 | 144-152 | ChemicalEntity | denotes | levodopa | http://purl.obolibrary.org/obo/CHEBI_15765 |
T3 | 297-305 | ChemicalEntity | denotes | levodopa | http://purl.obolibrary.org/obo/CHEBI_15765 |
T4 | 459-467 | ChemicalEntity | denotes | levodopa | http://purl.obolibrary.org/obo/CHEBI_15765 |
T5 | 824-832 | ChemicalEntity | denotes | levodopa | http://purl.obolibrary.org/obo/CHEBI_15765 |
T6 | 1085-1093 | ChemicalEntity | denotes | levodopa | http://purl.obolibrary.org/obo/CHEBI_15765 |
T7 | 1173-1181 | ChemicalEntity | denotes | levodopa | http://purl.obolibrary.org/obo/CHEBI_15765 |
T8 | 1342-1350 | ChemicalEntity | denotes | levodopa | http://purl.obolibrary.org/obo/CHEBI_15765 |
T9 | 1387-1395 | ChemicalEntity | denotes | levodopa | http://purl.obolibrary.org/obo/CHEBI_15765 |
T10 | 1433-1441 | ChemicalEntity | denotes | levodopa | http://purl.obolibrary.org/obo/CHEBI_15765 |
T11 | 1535-1543 | ChemicalEntity | denotes | levodopa | http://purl.obolibrary.org/obo/CHEBI_15765 |
T12 | 1565-1573 | ChemicalEntity | denotes | levodopa | http://purl.obolibrary.org/obo/CHEBI_15765 |
LitCoin-NCBITaxon-2
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 353-361 | OrganismTaxon | denotes | patients |
T2 | 425-433 | OrganismTaxon | denotes | patients |
T3 | 955-963 | OrganismTaxon | denotes | patients |
T4 | 1249-1257 | OrganismTaxon | denotes | patients |
T5 | 1468-1476 | OrganismTaxon | denotes | patients |
LitCoin-training-merged
Id | Subject | Object | Predicate | Lexical cue | #label | ID: |
---|---|---|---|---|---|---|
T12 | 1565-1573 | ChemicalEntity | denotes | levodopa | http://purl.obolibrary.org/obo/CHEBI_15765 | |
T11 | 1535-1543 | ChemicalEntity | denotes | levodopa | http://purl.obolibrary.org/obo/CHEBI_15765 | |
T10 | 1433-1441 | ChemicalEntity | denotes | levodopa | http://purl.obolibrary.org/obo/CHEBI_15765 | |
T9 | 1387-1395 | ChemicalEntity | denotes | levodopa | http://purl.obolibrary.org/obo/CHEBI_15765 | |
T8 | 1342-1350 | ChemicalEntity | denotes | levodopa | http://purl.obolibrary.org/obo/CHEBI_15765 | |
T7 | 1173-1181 | ChemicalEntity | denotes | levodopa | http://purl.obolibrary.org/obo/CHEBI_15765 | |
T6 | 1085-1093 | ChemicalEntity | denotes | levodopa | http://purl.obolibrary.org/obo/CHEBI_15765 | |
T5 | 824-832 | ChemicalEntity | denotes | levodopa | http://purl.obolibrary.org/obo/CHEBI_15765 | |
T4 | 459-467 | ChemicalEntity | denotes | levodopa | http://purl.obolibrary.org/obo/CHEBI_15765 | |
T3 | 297-305 | ChemicalEntity | denotes | levodopa | http://purl.obolibrary.org/obo/CHEBI_15765 | |
T2 | 144-152 | ChemicalEntity | denotes | levodopa | http://purl.obolibrary.org/obo/CHEBI_15765 | |
T1 | 31-39 | ChemicalEntity | denotes | levodopa | http://purl.obolibrary.org/obo/CHEBI_15765 | |
T15 | 1450-1460 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | D020820 | |
T14 | 1314-1324 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | D020820 | |
T13 | 1266-1276 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | D020820 | |
T74208 | 1021-1031 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | D020820 | |
T35478 | 969-979 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | D020820 | |
T5569 | 773-783 | DiseaseOrPhenotypicFeature | denotes | Dyskinesia | D020820 | |
T52246 | 567-577 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | D020820 | |
T37935 | 439-441 | DiseaseOrPhenotypicFeature | denotes | PD | D010300 | |
T68808 | 367-369 | DiseaseOrPhenotypicFeature | denotes | PD | D010300 | |
T66222 | 314-324 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | D020820 | |
T97672 | 241-251 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | D020820 | |
T32839 | 186-188 | DiseaseOrPhenotypicFeature | denotes | PD | D010300 | |
T55506 | 165-184 | DiseaseOrPhenotypicFeature | denotes | Parkinson's disease | D010300 | |
T50074 | 93-112 | DiseaseOrPhenotypicFeature | denotes | Parkinson's disease | D010300 | |
T27873 | 48-58 | DiseaseOrPhenotypicFeature | denotes | dyskinesia | D020820 | |
T17364 | 1468-1476 | OrganismTaxon | denotes | patients | ||
T62467 | 1249-1257 | OrganismTaxon | denotes | patients | ||
T68721 | 955-963 | OrganismTaxon | denotes | patients | ||
T28904 | 425-433 | OrganismTaxon | denotes | patients | ||
T49537 | 353-361 | OrganismTaxon | denotes | patients |
Allie
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
SS1_23952588_2_0 | 165-184 | expanded | denotes | Parkinson's disease |
SS2_23952588_2_0 | 186-188 | abbr | denotes | PD |
AE1_23952588_2_0 | SS1_23952588_2_0 | SS2_23952588_2_0 | abbreviatedTo | Parkinson's disease,PD |
PubmedHPO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 165-174 | HP_0001300 | denotes | Parkinson |
T2 | 241-251 | HP_0100660 | denotes | dyskinesia |
T3 | 314-324 | HP_0100660 | denotes | dyskinesia |