PubMed:23630944 / 722-975 JSONTXT

{"project":"DisGeNET5_gene_disease","denotations":[{"id":"23630944-0#50#54#gene5524","span":{"begin":0,"end":253},"obj":"gene5524"}],"text":"Pp2a activity and the regulation of its holoenzyme composition, with the polyglutamine mutation within Atxn1 altering this function in the SCA1 mouse cerebellum before disease onset. We show that ataxin-1 enhances Pp2a-bβ expression and down-regulates A"}

{"project":"DisGeNET","denotations":[{"id":"T15","span":{"begin":139,"end":143},"obj":"disease:C0752120"},{"id":"T16","span":{"begin":0,"end":4},"obj":"gene:5524"},{"id":"T17","span":{"begin":139,"end":143},"obj":"disease:C0752120"},{"id":"T18","span":{"begin":103,"end":108},"obj":"gene:6310"},{"id":"T19","span":{"begin":139,"end":143},"obj":"disease:C0752120"}],"relations":[{"id":"R9","pred":"associated_with","subj":"T16","obj":"T17"},{"id":"R10","pred":"associated_with","subj":"T18","obj":"T19"}],"namespaces":[{"prefix":"gene","uri":"http://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"disease","uri":"http://purl.bioontology.org/ontology/MEDLINEPLUS/"}],"text":"Pp2a activity and the regulation of its holoenzyme composition, with the polyglutamine mutation within Atxn1 altering this function in the SCA1 mouse cerebellum before disease onset. We show that ataxin-1 enhances Pp2a-bβ expression and down-regulates A"}