PubMed:2343592 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/2343592","sourcedb":"PubMed","sourceid":"2343592","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/2343592","text":"Seizure activity with imipenem therapy: incidence and risk factors.\nTwo elderly patients with a history of either cerebral vascular accident (CVA) or head trauma and no evidence of renal disease developed seizures while receiving maximum doses of imipenem/cilastatin. Neither patient had reported previous seizures or seizure-like activity nor was receiving anticonvulsant agents. All seizures were controlled with therapeutic doses of phenytoin. Both patients had received maximum doses of other beta-lactam antibiotics without evidence of seizure 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