PubMed:2343592 JSONTXT

{"project":"PubmedHPO","denotations":[{"id":"T1","span":{"begin":205,"end":213},"obj":"HP_0001250"},{"id":"T2","span":{"begin":306,"end":314},"obj":"HP_0001250"},{"id":"T3","span":{"begin":318,"end":325},"obj":"HP_0001250"},{"id":"T4","span":{"begin":385,"end":393},"obj":"HP_0001250"},{"id":"T5","span":{"begin":541,"end":548},"obj":"HP_0001250"}],"text":"Seizure activity with imipenem therapy: incidence and risk factors.\nTwo elderly patients with a history of either cerebral vascular accident (CVA) or head trauma and no evidence of renal disease developed seizures while receiving maximum doses of imipenem/cilastatin. Neither patient had reported previous seizures or seizure-like activity nor was receiving anticonvulsant agents. All seizures were controlled with therapeutic doses of phenytoin. Both patients had received maximum doses of other beta-lactam antibiotics without evidence of seizure activity."}

{"project":"PubCasesHPO","denotations":[{"id":"TI1","span":{"begin":0,"end":7},"obj":"HP:0001250"},{"id":"AB1","span":{"begin":205,"end":213},"obj":"HP:0001250"},{"id":"AB2","span":{"begin":306,"end":314},"obj":"HP:0001250"},{"id":"AB3","span":{"begin":318,"end":325},"obj":"HP:0001250"},{"id":"AB4","span":{"begin":385,"end":393},"obj":"HP:0001250"},{"id":"AB5","span":{"begin":541,"end":548},"obj":"HP:0001250"}],"text":"Seizure activity with imipenem therapy: incidence and risk factors.\nTwo elderly patients with a history of either cerebral vascular accident (CVA) or head trauma and no evidence of renal disease developed seizures while receiving maximum doses of imipenem/cilastatin. Neither patient had reported previous seizures or seizure-like activity nor was receiving anticonvulsant agents. All seizures were controlled with therapeutic doses of phenytoin. Both patients had received maximum doses of other beta-lactam antibiotics without evidence of seizure activity."}

{"project":"bc5cdr-valid-experiment","denotations":[{"id":"T1","span":{"begin":0,"end":7},"obj":"Disease"},{"id":"T2","span":{"begin":22,"end":30},"obj":"Chemical"},{"id":"T3","span":{"begin":114,"end":140},"obj":"Disease"},{"id":"T4","span":{"begin":142,"end":145},"obj":"Disease"},{"id":"T5","span":{"begin":150,"end":161},"obj":"Disease"},{"id":"T6","span":{"begin":181,"end":194},"obj":"Disease"},{"id":"T7","span":{"begin":205,"end":213},"obj":"Disease"},{"id":"T8","span":{"begin":247,"end":266},"obj":"Chemical"},{"id":"T9","span":{"begin":306,"end":314},"obj":"Disease"},{"id":"T10","span":{"begin":318,"end":325},"obj":"Disease"},{"id":"T11","span":{"begin":385,"end":393},"obj":"Disease"},{"id":"T12","span":{"begin":436,"end":445},"obj":"Chemical"},{"id":"T13","span":{"begin":497,"end":508},"obj":"Chemical"},{"id":"T14","span":{"begin":541,"end":548},"obj":"Disease"}],"text":"Seizure activity with imipenem therapy: incidence and risk factors.\nTwo elderly patients with a history of either cerebral vascular accident (CVA) or head trauma and no evidence of renal disease developed seizures while receiving maximum doses of imipenem/cilastatin. Neither patient had reported previous seizures or seizure-like activity nor was receiving anticonvulsant agents. All seizures were controlled with therapeutic doses of phenytoin. Both patients had received maximum doses of other beta-lactam antibiotics without evidence of seizure activity."}

{"project":"bc5cdr-valid-deepseek-nr-ng-experiment","denotations":[{"id":"T1","span":{"begin":22,"end":30},"obj":"Chemical"},{"id":"T2","span":{"begin":142,"end":145},"obj":"Disease"},{"id":"T3","span":{"begin":150,"end":161},"obj":"Disease"},{"id":"T4","span":{"begin":181,"end":194},"obj":"Disease"},{"id":"T5","span":{"begin":205,"end":213},"obj":"Disease"},{"id":"T6","span":{"begin":247,"end":266},"obj":"Chemical"},{"id":"T7","span":{"begin":318,"end":339},"obj":"Disease"},{"id":"T8","span":{"begin":385,"end":392},"obj":"Disease"},{"id":"T9","span":{"begin":436,"end":445},"obj":"Chemical"},{"id":"T10","span":{"begin":497,"end":520},"obj":"Chemical"}],"text":"Seizure activity with imipenem therapy: incidence and risk factors.\nTwo elderly patients with a history of either cerebral vascular accident (CVA) or head trauma and no evidence of renal disease developed seizures while receiving maximum doses of imipenem/cilastatin. Neither patient had reported previous seizures or seizure-like activity nor was receiving anticonvulsant agents. All seizures were controlled with therapeutic doses of phenytoin. Both patients had received maximum doses of other beta-lactam antibiotics without evidence of seizure activity."}

{"project":"bc5cdr-valid-deepseek-nr-g-experiment","denotations":[{"id":"T1","span":{"begin":0,"end":7},"obj":"Disease"},{"id":"T2","span":{"begin":8,"end":16},"obj":"Disease"},{"id":"T3","span":{"begin":22,"end":30},"obj":"Chemical"},{"id":"T4","span":{"begin":80,"end":88},"obj":"Disease"},{"id":"T5","span":{"begin":114,"end":140},"obj":"Disease"},{"id":"T6","span":{"begin":142,"end":145},"obj":"Disease"},{"id":"T7","span":{"begin":150,"end":161},"obj":"Disease"},{"id":"T8","span":{"begin":181,"end":194},"obj":"Disease"},{"id":"T9","span":{"begin":205,"end":213},"obj":"Disease"},{"id":"T10","span":{"begin":247,"end":255},"obj":"Chemical"},{"id":"T11","span":{"begin":256,"end":266},"obj":"Chemical"},{"id":"T12","span":{"begin":306,"end":314},"obj":"Disease"},{"id":"T13","span":{"begin":318,"end":339},"obj":"Disease"},{"id":"T14","span":{"begin":358,"end":372},"obj":"Chemical"},{"id":"T15","span":{"begin":385,"end":393},"obj":"Disease"},{"id":"T16","span":{"begin":436,"end":445},"obj":"Chemical"},{"id":"T17","span":{"begin":549,"end":557},"obj":"Disease"}],"text":"Seizure activity with imipenem therapy: incidence and risk factors.\nTwo elderly patients with a history of either cerebral vascular accident (CVA) or head trauma and no evidence of renal disease developed seizures while receiving maximum doses of imipenem/cilastatin. Neither patient had reported previous seizures or seizure-like activity nor was receiving anticonvulsant agents. All seizures were controlled with therapeutic doses of phenytoin. Both patients had received maximum doses of other beta-lactam antibiotics without evidence of seizure activity."}

{"project":"bc5cdr-valid-gpt-r-ng-experiment","denotations":[{"id":"T1","span":{"begin":0,"end":16},"obj":"Disease"},{"id":"T2","span":{"begin":22,"end":30},"obj":"Chemical"},{"id":"T3","span":{"begin":114,"end":146},"obj":"Disease"},{"id":"T4","span":{"begin":150,"end":161},"obj":"Disease"},{"id":"T5","span":{"begin":181,"end":194},"obj":"Disease"},{"id":"T6","span":{"begin":205,"end":213},"obj":"Disease"},{"id":"T7","span":{"begin":247,"end":266},"obj":"Chemical"},{"id":"T8","span":{"begin":306,"end":314},"obj":"Disease"},{"id":"T9","span":{"begin":318,"end":339},"obj":"Disease"},{"id":"T10","span":{"begin":358,"end":379},"obj":"Chemical"},{"id":"T11","span":{"begin":385,"end":393},"obj":"Disease"},{"id":"T12","span":{"begin":436,"end":445},"obj":"Chemical"},{"id":"T13","span":{"begin":497,"end":520},"obj":"Chemical"},{"id":"T14","span":{"begin":541,"end":557},"obj":"Disease"}],"text":"Seizure activity with imipenem therapy: incidence and risk factors.\nTwo elderly patients with a history of either cerebral vascular accident (CVA) or head trauma and no evidence of renal disease developed seizures while receiving maximum doses of imipenem/cilastatin. Neither patient had reported previous seizures or seizure-like activity nor was receiving anticonvulsant agents. All seizures were controlled with therapeutic doses of phenytoin. Both patients had received maximum doses of other beta-lactam antibiotics without evidence of seizure activity."}

{"project":"bc5cdr-valid-gpt-r-g-experiment","denotations":[{"id":"T1","span":{"begin":0,"end":7},"obj":"Disease"},{"id":"T2","span":{"begin":22,"end":30},"obj":"Chemical"},{"id":"T3","span":{"begin":114,"end":140},"obj":"Disease"},{"id":"T4","span":{"begin":142,"end":145},"obj":"Disease"},{"id":"T5","span":{"begin":150,"end":161},"obj":"Disease"},{"id":"T6","span":{"begin":181,"end":194},"obj":"Disease"},{"id":"T7","span":{"begin":205,"end":213},"obj":"Disease"},{"id":"T8","span":{"begin":247,"end":266},"obj":"Chemical"},{"id":"T9","span":{"begin":306,"end":314},"obj":"Disease"},{"id":"T10","span":{"begin":385,"end":393},"obj":"Disease"},{"id":"T11","span":{"begin":436,"end":445},"obj":"Chemical"},{"id":"T12","span":{"begin":497,"end":520},"obj":"Chemical"},{"id":"T13","span":{"begin":541,"end":548},"obj":"Disease"}],"text":"Seizure activity with imipenem therapy: incidence and risk factors.\nTwo elderly patients with a history of either cerebral vascular accident (CVA) or head trauma and no evidence of renal disease developed seizures while receiving maximum doses of imipenem/cilastatin. Neither patient had reported previous seizures or seizure-like activity nor was receiving anticonvulsant agents. All seizures were controlled with therapeutic doses of phenytoin. Both patients had received maximum doses of other beta-lactam antibiotics without evidence of seizure activity."}

{"project":"bc5cdr-valid-gpt-r-m30","denotations":[{"id":"T1","span":{"begin":0,"end":7},"obj":"Disease"},{"id":"T2","span":{"begin":22,"end":30},"obj":"Chemical"},{"id":"T3","span":{"begin":114,"end":140},"obj":"Disease"},{"id":"T4","span":{"begin":142,"end":145},"obj":"Disease"},{"id":"T5","span":{"begin":150,"end":161},"obj":"Disease"},{"id":"T6","span":{"begin":181,"end":194},"obj":"Disease"},{"id":"T7","span":{"begin":205,"end":213},"obj":"Disease"},{"id":"T8","span":{"begin":247,"end":266},"obj":"Chemical"},{"id":"T9","span":{"begin":306,"end":314},"obj":"Disease"},{"id":"T10","span":{"begin":385,"end":393},"obj":"Disease"},{"id":"T11","span":{"begin":436,"end":445},"obj":"Chemical"},{"id":"T12","span":{"begin":497,"end":508},"obj":"Chemical"},{"id":"T13","span":{"begin":541,"end":548},"obj":"Disease"}],"text":"Seizure activity with imipenem therapy: incidence and risk factors.\nTwo elderly patients with a history of either cerebral vascular accident (CVA) or head trauma and no evidence of renal disease developed seizures while receiving maximum doses of imipenem/cilastatin. Neither patient had reported previous seizures or seizure-like activity nor was receiving anticonvulsant agents. All seizures were controlled with therapeutic doses of phenytoin. Both patients had received maximum doses of other beta-lactam antibiotics without evidence of seizure activity."}

{"project":"bc5cdr-valid-gpt-r-m20","denotations":[{"id":"T1","span":{"begin":0,"end":7},"obj":"Disease"},{"id":"T2","span":{"begin":22,"end":30},"obj":"Chemical"},{"id":"T3","span":{"begin":114,"end":140},"obj":"Disease"},{"id":"T4","span":{"begin":142,"end":145},"obj":"Disease"},{"id":"T5","span":{"begin":150,"end":161},"obj":"Disease"},{"id":"T6","span":{"begin":181,"end":194},"obj":"Disease"},{"id":"T7","span":{"begin":205,"end":213},"obj":"Disease"},{"id":"T8","span":{"begin":247,"end":266},"obj":"Chemical"},{"id":"T9","span":{"begin":306,"end":314},"obj":"Disease"},{"id":"T10","span":{"begin":385,"end":393},"obj":"Disease"},{"id":"T11","span":{"begin":436,"end":445},"obj":"Chemical"},{"id":"T12","span":{"begin":497,"end":508},"obj":"Chemical"},{"id":"T13","span":{"begin":541,"end":548},"obj":"Disease"}],"text":"Seizure activity with imipenem therapy: incidence and risk factors.\nTwo elderly patients with a history of either cerebral vascular accident (CVA) or head trauma and no evidence of renal disease developed seizures while receiving maximum doses of imipenem/cilastatin. Neither patient had reported previous seizures or seizure-like activity nor was receiving anticonvulsant agents. All seizures were controlled with therapeutic doses of phenytoin. Both patients had received maximum doses of other beta-lactam antibiotics without evidence of seizure activity."}