PubMed:23208007
Annnotations
Glycan-Motif
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-15 | https://glytoucan.org/Structures/Glycans/G00065MO | denotes | Polysialic acid |
| T2 | 79-94 | https://glytoucan.org/Structures/Glycans/G00065MO | denotes | Polysialic acid |
| T3 | 96-103 | https://glytoucan.org/Structures/Glycans/G00065MO | denotes | polySia |
| T4 | 173-184 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | sialic acid |
| T5 | 609-616 | https://glytoucan.org/Structures/Glycans/G00065MO | denotes | polySia |
| T6 | 929-936 | https://glytoucan.org/Structures/Glycans/G00065MO | denotes | polySia |
| T7 | 1158-1165 | https://glytoucan.org/Structures/Glycans/G00065MO | denotes | polySia |
GlyCosmos6-Glycan-Motif-Image
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 0-15 | Glycan_Motif | denotes | Polysialic acid | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00065MO |
| T2 | 79-94 | Glycan_Motif | denotes | Polysialic acid | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00065MO |
| T3 | 96-103 | Glycan_Motif | denotes | polySia | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00065MO |
| T4 | 173-184 | Glycan_Motif | denotes | sialic acid | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY |
| T5 | 609-616 | Glycan_Motif | denotes | polySia | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00065MO |
| T6 | 929-936 | Glycan_Motif | denotes | polySia | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00065MO |
| T7 | 1158-1165 | Glycan_Motif | denotes | polySia | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00065MO |
Glycosmos6-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 227-241 | http://purl.obolibrary.org/obo/MAT_0000026 | denotes | nervous system |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TextSentencer_T1 | 0-78 | Sentence | denotes | Polysialic acid enhances the migration and invasion of human cytotrophoblasts. |
| TextSentencer_T2 | 79-194 | Sentence | denotes | Polysialic acid (polySia) is a large, cell-surface linear homopolymer composed of α2,8-linked sialic acid residues. |
| TextSentencer_T3 | 195-343 | Sentence | denotes | Most extensively studied in the nervous system, this unique glycan modulates development by enhancing cell migration and regulating differentiation. |
| TextSentencer_T4 | 344-441 | Sentence | denotes | PolySia also functions in developing and adult immune systems and is a signature of many cancers. |
| TextSentencer_T5 | 442-556 | Sentence | denotes | In this study, we demonstrated that human placental trophoblasts, an epithelial lineage, also display this glycan. |
| TextSentencer_T6 | 557-692 | Sentence | denotes | Cytotrophoblasts and syncytiotrophoblasts expressed polySia in the first trimester and downregulated it during the course of pregnancy. |
| TextSentencer_T7 | 693-784 | Sentence | denotes | PolySia promoted cytotrophoblast migration in an explant model of chorionic villous growth. |
| TextSentencer_T8 | 785-904 | Sentence | denotes | Removal of this glycan also reduced cytotrophoblast penetration of basement membranes in an in vitro model of invasion. |
| TextSentencer_T9 | 905-1088 | Sentence | denotes | Finally, we showed that polySia was overexpressed in biopsies from patients with gestational trophoblastic diseases, including benign molar pregnancies and malignant choriocarcinomas. |
| TextSentencer_T10 | 1089-1305 | Sentence | denotes | These results demonstrated, for the first time, functional roles for polySia during normal human placental development and implicated these unusual oligosaccharides in the unrestrained invasion of trophoblast tumors. |
| T1 | 0-78 | Sentence | denotes | Polysialic acid enhances the migration and invasion of human cytotrophoblasts. |
| T2 | 79-194 | Sentence | denotes | Polysialic acid (polySia) is a large, cell-surface linear homopolymer composed of α2,8-linked sialic acid residues. |
| T3 | 195-343 | Sentence | denotes | Most extensively studied in the nervous system, this unique glycan modulates development by enhancing cell migration and regulating differentiation. |
| T4 | 344-441 | Sentence | denotes | PolySia also functions in developing and adult immune systems and is a signature of many cancers. |
| T5 | 442-556 | Sentence | denotes | In this study, we demonstrated that human placental trophoblasts, an epithelial lineage, also display this glycan. |
| T6 | 557-692 | Sentence | denotes | Cytotrophoblasts and syncytiotrophoblasts expressed polySia in the first trimester and downregulated it during the course of pregnancy. |
| T7 | 693-784 | Sentence | denotes | PolySia promoted cytotrophoblast migration in an explant model of chorionic villous growth. |
| T8 | 785-904 | Sentence | denotes | Removal of this glycan also reduced cytotrophoblast penetration of basement membranes in an in vitro model of invasion. |
| T9 | 905-1088 | Sentence | denotes | Finally, we showed that polySia was overexpressed in biopsies from patients with gestational trophoblastic diseases, including benign molar pregnancies and malignant choriocarcinomas. |
| T10 | 1089-1305 | Sentence | denotes | These results demonstrated, for the first time, functional roles for polySia during normal human placental development and implicated these unusual oligosaccharides in the unrestrained invasion of trophoblast tumors. |
| T1 | 0-78 | Sentence | denotes | Polysialic acid enhances the migration and invasion of human cytotrophoblasts. |
| T2 | 79-194 | Sentence | denotes | Polysialic acid (polySia) is a large, cell-surface linear homopolymer composed of α2,8-linked sialic acid residues. |
| T3 | 195-343 | Sentence | denotes | Most extensively studied in the nervous system, this unique glycan modulates development by enhancing cell migration and regulating differentiation. |
| T4 | 344-441 | Sentence | denotes | PolySia also functions in developing and adult immune systems and is a signature of many cancers. |
| T5 | 442-556 | Sentence | denotes | In this study, we demonstrated that human placental trophoblasts, an epithelial lineage, also display this glycan. |
| T6 | 557-692 | Sentence | denotes | Cytotrophoblasts and syncytiotrophoblasts expressed polySia in the first trimester and downregulated it during the course of pregnancy. |
| T7 | 693-784 | Sentence | denotes | PolySia promoted cytotrophoblast migration in an explant model of chorionic villous growth. |
| T8 | 785-904 | Sentence | denotes | Removal of this glycan also reduced cytotrophoblast penetration of basement membranes in an in vitro model of invasion. |
| T9 | 905-1088 | Sentence | denotes | Finally, we showed that polySia was overexpressed in biopsies from patients with gestational trophoblastic diseases, including benign molar pregnancies and malignant choriocarcinomas. |
| T10 | 1089-1305 | Sentence | denotes | These results demonstrated, for the first time, functional roles for polySia during normal human placental development and implicated these unusual oligosaccharides in the unrestrained invasion of trophoblast tumors. |
GlyCosmos6-Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-15 | https://glytoucan.org/Structures/Glycans/G00065MO | denotes | Polysialic acid |
| T2 | 79-94 | https://glytoucan.org/Structures/Glycans/G00065MO | denotes | Polysialic acid |
| T3 | 173-184 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | sialic acid |
ICD10
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 227-234 | http://purl.bioontology.org/ontology/ICD10/R45.0 | denotes | nervous |
GlycoBiology-FMA
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| _T1 | 61-77 | FMAID:200947 | denotes | cytotrophoblasts |
| _T2 | 61-77 | FMAID:83039 | denotes | cytotrophoblasts |
| _T3 | 61-77 | FMAID:197301 | denotes | cytotrophoblasts |
| _T4 | 117-129 | FMAID:212684 | denotes | cell-surface |
| _T5 | 117-129 | FMAID:200942 | denotes | cell-surface |
| _T6 | 122-129 | FMAID:50594 | denotes | surface |
| _T7 | 122-129 | FMAID:146300 | denotes | surface |
| _T8 | 227-241 | FMAID:7157 | denotes | nervous system |
| _T9 | 227-241 | FMAID:93586 | denotes | nervous system |
| _T10 | 391-405 | FMAID:9825 | denotes | immune systems |
| _T11 | 391-405 | FMAID:97740 | denotes | immune systems |
| _T12 | 494-506 | FMAID:197289 | denotes | trophoblasts |
| _T13 | 494-506 | FMAID:83029 | denotes | trophoblasts |
| _T14 | 557-573 | FMAID:83039 | denotes | Cytotrophoblasts |
| _T15 | 557-573 | FMAID:197301 | denotes | Cytotrophoblasts |
| _T16 | 557-573 | FMAID:200947 | denotes | Cytotrophoblasts |
| _T17 | 578-598 | FMAID:83040 | denotes | syncytiotrophoblasts |
| _T18 | 578-598 | FMAID:83043 | denotes | syncytiotrophoblasts |
| _T19 | 578-598 | FMAID:197308 | denotes | syncytiotrophoblasts |
| _T20 | 578-598 | FMAID:197302 | denotes | syncytiotrophoblasts |
| _T21 | 578-598 | FMAID:197303 | denotes | syncytiotrophoblasts |
| _T22 | 578-598 | FMAID:201968 | denotes | syncytiotrophoblasts |
| _T23 | 710-725 | FMAID:200947 | denotes | cytotrophoblast |
| _T24 | 710-725 | FMAID:83039 | denotes | cytotrophoblast |
| _T25 | 710-725 | FMAID:197301 | denotes | cytotrophoblast |
| _T26 | 759-768 | FMAID:80224 | denotes | chorionic |
| _T27 | 759-768 | FMAID:188332 | denotes | chorionic |
| _T28 | 821-836 | FMAID:197301 | denotes | cytotrophoblast |
| _T29 | 821-836 | FMAID:83039 | denotes | cytotrophoblast |
| _T30 | 821-836 | FMAID:200947 | denotes | cytotrophoblast |
| _T31 | 852-870 | FMAID:167247 | denotes | basement membranes |
| _T32 | 852-870 | FMAID:63872 | denotes | basement membranes |
| _T33 | 861-870 | FMAID:30322 | denotes | membranes |
| _T34 | 861-870 | FMAID:93573 | denotes | membranes |
| _T35 | 861-870 | FMAID:7145 | denotes | membranes |
| _T36 | 861-870 | FMAID:167608 | denotes | membranes |
| _T37 | 998-1011 | FMAID:83029 | denotes | trophoblastic |
| _T38 | 998-1011 | FMAID:197289 | denotes | trophoblastic |
| _T39 | 1237-1253 | FMAID:82742 | denotes | oligosaccharides |
| _T40 | 1237-1253 | FMAID:196731 | denotes | oligosaccharides |
| _T41 | 1286-1297 | FMAID:83029 | denotes | trophoblast |
| _T42 | 1286-1297 | FMAID:197289 | denotes | trophoblast |
GlycoBiology-NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 428-432 | http://purl.bioontology.org/ontology/NCBITAXON/9973 | denotes | many |
| T2 | 433-440 | http://purl.bioontology.org/ontology/NCBITAXON/6754 | denotes | cancers |
| T3 | 759-768 | http://purl.bioontology.org/ontology/NCBITAXON/387016 | denotes | chorionic |
GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 272-283 | http://purl.obolibrary.org/obo/GO_0032502 | denotes | development |
| T2 | 370-380 | http://purl.obolibrary.org/obo/GO_0032502 | denotes | developing |
| T3 | 297-311 | http://purl.obolibrary.org/obo/GO_0016477 | denotes | cell migration |
| T4 | 297-326 | http://purl.obolibrary.org/obo/GO_0010762 | denotes | cell migration and regulating |
| T5 | 297-326 | http://purl.obolibrary.org/obo/GO_0030335 | denotes | cell migration and regulating |
| T6 | 297-326 | http://purl.obolibrary.org/obo/GO_0030336 | denotes | cell migration and regulating |
| T7 | 297-326 | http://purl.obolibrary.org/obo/GO_1903684 | denotes | cell migration and regulating |
| T8 | 297-326 | http://purl.obolibrary.org/obo/GO_2000274 | denotes | cell migration and regulating |
| T9 | 297-326 | http://purl.obolibrary.org/obo/GO_0002685 | denotes | cell migration and regulating |
| T10 | 297-326 | http://purl.obolibrary.org/obo/GO_0071675 | denotes | cell migration and regulating |
| T11 | 297-326 | http://purl.obolibrary.org/obo/GO_1903975 | denotes | cell migration and regulating |
| T12 | 316-326 | http://purl.obolibrary.org/obo/GO_0065007 | denotes | regulating |
| T13 | 484-493 | http://purl.obolibrary.org/obo/GO_0001890 | denotes | placental |
| T14 | 1186-1195 | http://purl.obolibrary.org/obo/GO_0001890 | denotes | placental |
| T15 | 777-783 | http://purl.obolibrary.org/obo/GO_0040007 | denotes | growth |
| T16 | 986-997 | http://purl.obolibrary.org/obo/GO_0007565 | denotes | gestational |
| T17 | 1186-1207 | http://purl.obolibrary.org/obo/GO_0001890 | denotes | placental development |
GO-CC
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 117-121 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T2 | 297-301 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T3 | 117-129 | http://purl.obolibrary.org/obo/GO_0009986 | denotes | cell-surface |
| T4 | 852-870 | http://purl.obolibrary.org/obo/GO_0005604 | denotes | basement membranes |
| T5 | 861-870 | http://purl.obolibrary.org/obo/GO_0016020 | denotes | membranes |
UBERON-AE
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 61-77 | http://purl.obolibrary.org/obo/UBERON_0000319 | denotes | cytotrophoblasts |
| T2 | 710-725 | http://purl.obolibrary.org/obo/UBERON_0000319 | denotes | cytotrophoblast |
| T3 | 821-836 | http://purl.obolibrary.org/obo/UBERON_0000319 | denotes | cytotrophoblast |
| T4 | 200-211 | http://purl.obolibrary.org/obo/UBERON_2000106 | denotes | extensively |
| T5 | 227-241 | http://purl.obolibrary.org/obo/UBERON_0001016 | denotes | nervous system |
| T6 | 391-405 | http://purl.obolibrary.org/obo/UBERON_0002405 | denotes | immune systems |
| T7 | 494-506 | http://purl.obolibrary.org/obo/UBERON_0000088 | denotes | trophoblasts |
| T8 | 998-1011 | http://purl.obolibrary.org/obo/UBERON_0000088 | denotes | trophoblastic |
| T9 | 1286-1297 | http://purl.obolibrary.org/obo/UBERON_0000088 | denotes | trophoblast |
| T10 | 578-598 | http://purl.obolibrary.org/obo/UBERON_0000371 | denotes | syncytiotrophoblasts |
| T11 | 759-768 | http://purl.obolibrary.org/obo/UBERON_0003124 | denotes | chorionic |
EDAM-topics
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 55-60 | http://edamontology.org/topic_2815 | denotes | human |
| T2 | 212-219 | http://edamontology.org/topic_3678 | denotes | studied |
| T3 | 433-440 | http://edamontology.org/topic_2640 | denotes | cancers |
| T4 | 450-455 | http://edamontology.org/topic_3678 | denotes | study |
| T5 | 478-483 | http://edamontology.org/topic_2815 | denotes | human |
| T6 | 701-709 | http://edamontology.org/topic_1312 | denotes | promoted |
| T7 | 701-709 | http://edamontology.org/topic_0111 | denotes | promoted |
| T8 | 701-709 | http://edamontology.org/topic_0749 | denotes | promoted |
| T9 | 1012-1020 | http://edamontology.org/topic_0634 | denotes | diseases |
| T10 | 1180-1185 | http://edamontology.org/topic_2815 | denotes | human |
EDAM-DFO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 185-193 | http://edamontology.org/data_1756 | denotes | residues |
| T2 | 357-366 | http://edamontology.org/operation_0004 | denotes | functions |
| T3 | 460-472 | http://edamontology.org/operation_2246 | denotes | demonstrated |
| T4 | 1103-1115 | http://edamontology.org/operation_2246 | denotes | demonstrated |
| T5 | 1173-1179 | http://edamontology.org/operation_3435 | denotes | normal |
Allie
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| SS1_23208007_1_0 | 79-94 | expanded | denotes | Polysialic acid |
| SS2_23208007_1_0 | 96-103 | abbr | denotes | polySia |
| AE1_23208007_1_0 | SS1_23208007_1_0 | SS2_23208007_1_0 | abbreviatedTo | Polysialic acid,polySia |
PubmedHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 433-440 | HP_0002664 | denotes | cancers |
| T2 | 1071-1087 | HP_0100768 | denotes | choriocarcinomas |
| T3 | 1298-1304 | HP_0002664 | denotes | tumors |
GlycoBiology-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 227-241 | http://purl.obolibrary.org/obo/MAT_0000026 | denotes | nervous system |
performance-test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-UBERON-AE-B_T1 | 484-493 | http://purl.obolibrary.org/obo/UBERON_0001987 | denotes | placental |
| PD-UBERON-AE-B_T2 | 1186-1195 | http://purl.obolibrary.org/obo/UBERON_0001987 | denotes | placental |
| PD-UBERON-AE-B_T3 | 227-241 | http://purl.obolibrary.org/obo/UBERON_0001016 | denotes | nervous system |
| PD-UBERON-AE-B_T4 | 759-768 | http://purl.obolibrary.org/obo/UBERON_0003124 | denotes | chorionic |
| PD-UBERON-AE-B_T5 | 61-77 | http://purl.obolibrary.org/obo/UBERON_0000319 | denotes | cytotrophoblasts |
| PD-UBERON-AE-B_T6 | 557-573 | http://purl.obolibrary.org/obo/UBERON_0000319 | denotes | Cytotrophoblasts |
| PD-UBERON-AE-B_T7 | 710-725 | http://purl.obolibrary.org/obo/UBERON_0000319 | denotes | cytotrophoblast |
| PD-UBERON-AE-B_T8 | 821-836 | http://purl.obolibrary.org/obo/UBERON_0000319 | denotes | cytotrophoblast |
| PD-UBERON-AE-B_T9 | 200-211 | http://purl.obolibrary.org/obo/UBERON_2000106 | denotes | extensively |
| PD-UBERON-AE-B_T10 | 391-405 | http://purl.obolibrary.org/obo/UBERON_0002405 | denotes | immune systems |
| PD-UBERON-AE-B_T11 | 494-506 | http://purl.obolibrary.org/obo/UBERON_0000088 | denotes | trophoblasts |
| PD-UBERON-AE-B_T12 | 998-1011 | http://purl.obolibrary.org/obo/UBERON_0000088 | denotes | trophoblastic |
| PD-UBERON-AE-B_T13 | 1286-1297 | http://purl.obolibrary.org/obo/UBERON_0000088 | denotes | trophoblast |
| PD-UBERON-AE-B_T14 | 578-598 | http://purl.obolibrary.org/obo/UBERON_0000371 | denotes | syncytiotrophoblasts |
CHEMDNER-training-test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 173-184 | TRIVIAL | denotes | sialic acid |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 227-241 | Body_part | denotes | nervous system | http://purl.obolibrary.org/obo/MAT_0000026 |
HP-phenotype
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 1071-1087 | Phenotype | denotes | choriocarcinomas | HP:0100768 |
| T2 | 1286-1304 | Phenotype | denotes | trophoblast tumors | HP:0031502 |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 986-1020 | Disease | denotes | gestational trophoblastic diseases | http://purl.obolibrary.org/obo/MONDO_0009273|http://purl.obolibrary.org/obo/MONDO_0016784|http://purl.obolibrary.org/obo/MONDO_0018944 |
| T4 | 1039-1056 | Disease | denotes | molar pregnancies | http://purl.obolibrary.org/obo/MONDO_0006248|http://purl.obolibrary.org/obo/MONDO_0018944 |
| T6 | 1071-1087 | Disease | denotes | choriocarcinomas | http://purl.obolibrary.org/obo/MONDO_0005207 |
| T7 | 1286-1304 | Disease | denotes | trophoblast tumors | http://purl.obolibrary.org/obo/MONDO_0002872 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 55-60 | OrganismTaxon | denotes | human | 9606 |
| T2 | 478-483 | OrganismTaxon | denotes | human | 9606 |
| T3 | 1180-1185 | OrganismTaxon | denotes | human | 9606 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T3 | 391-405 | Body_part | denotes | immune systems | http://purl.obolibrary.org/obo/UBERON_0002405 |
| T4 | 494-506 | Body_part | denotes | trophoblasts | http://purl.obolibrary.org/obo/UBERON_0000088 |
| T5 | 557-573 | Body_part | denotes | Cytotrophoblasts | http://purl.obolibrary.org/obo/UBERON_0000319 |
| T6 | 578-598 | Body_part | denotes | syncytiotrophoblasts | http://purl.obolibrary.org/obo/UBERON_0000371 |
| T7 | 710-725 | Body_part | denotes | cytotrophoblast | http://purl.obolibrary.org/obo/UBERON_0000319 |
| T8 | 759-776 | Body_part | denotes | chorionic villous | http://purl.obolibrary.org/obo/UBERON_0007106 |
| T9 | 821-836 | Body_part | denotes | cytotrophoblast | http://purl.obolibrary.org/obo/UBERON_0000319 |
| T10 | 852-870 | Body_part | denotes | basement membranes | http://purl.obolibrary.org/obo/GO_0005604|http://purl.obolibrary.org/obo/UBERON_0005769 |
| T12 | 998-1011 | Body_part | denotes | trophoblastic | http://purl.obolibrary.org/obo/UBERON_0000088 |
| T13 | 1039-1044 | Body_part | denotes | molar | http://purl.obolibrary.org/obo/UBERON_0003655 |
| T14 | 1286-1297 | Body_part | denotes | trophoblast | http://purl.obolibrary.org/obo/UBERON_0000088 |
| T1 | 61-77 | Body_part | denotes | cytotrophoblasts | http://purl.obolibrary.org/obo/UBERON_0000319 |
| T2 | 227-241 | Body_part | denotes | nervous system | http://purl.obolibrary.org/obo/UBERON_0001016 |