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PubMed:23083294 JSONTXT

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Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-56 Sentence denotes Association of HLA locus variant in Parkinson's disease.
T2 57-295 Sentence denotes A variant (rs3129882) in the genome-wide association study (GWAS)-linked variant [in the human leukocyte antigen (HLA) gene region] has been reported to associate with an increased risk of Parkinson's disease (PD) in Caucasian population.
T3 296-330 Sentence denotes Studies among Chinese are limited.
T4 331-494 Sentence denotes To address this, we analysed rs3129882 in a total of 1312 subjects of Chinese ethnicity from independent Asian centers comprising of 675 controls and 637 PD cases.
T5 495-588 Sentence denotes The rs3129882 variant was associated with a decreased risk in our ethnic Chinese PD patients.
T6 589-822 Sentence denotes Logistic regression analysis taking into consideration variables of age, gender and race showed that allele A reduced the risk of PD via a dominant model [odds ratio (OR) = 0.77, 95% confidence interval (CI) = 0.62, 0.96, p = 0.018].
T7 823-1009 Sentence denotes As HLA is a highly polymorphic region, it is possible that ethnic-specific effect or environmental agents may modulate the effect of this GWAS-linked locus in influencing the risk of PD.
T1 0-56 Sentence denotes Association of HLA locus variant in Parkinson's disease.
T2 57-295 Sentence denotes A variant (rs3129882) in the genome-wide association study (GWAS)-linked variant [in the human leukocyte antigen (HLA) gene region] has been reported to associate with an increased risk of Parkinson's disease (PD) in Caucasian population.
T3 296-330 Sentence denotes Studies among Chinese are limited.
T4 331-494 Sentence denotes To address this, we analysed rs3129882 in a total of 1312 subjects of Chinese ethnicity from independent Asian centers comprising of 675 controls and 637 PD cases.
T5 495-588 Sentence denotes The rs3129882 variant was associated with a decreased risk in our ethnic Chinese PD patients.
T6 589-822 Sentence denotes Logistic regression analysis taking into consideration variables of age, gender and race showed that allele A reduced the risk of PD via a dominant model [odds ratio (OR) = 0.77, 95% confidence interval (CI) = 0.62, 0.96, p = 0.018].
T7 823-1009 Sentence denotes As HLA is a highly polymorphic region, it is possible that ethnic-specific effect or environmental agents may modulate the effect of this GWAS-linked locus in influencing the risk of PD.

Allie

Id Subject Object Predicate Lexical cue
SS1_23083294_1_0 86-115 expanded denotes genome-wide association study
SS2_23083294_1_0 117-121 abbr denotes GWAS
SS1_23083294_1_1 146-169 expanded denotes human leukocyte antigen
SS2_23083294_1_1 171-174 abbr denotes HLA
SS1_23083294_1_2 246-265 expanded denotes Parkinson's disease
SS2_23083294_1_2 267-269 abbr denotes PD
SS1_23083294_5_0 744-754 expanded denotes odds ratio
SS2_23083294_5_0 756-758 abbr denotes OR
SS1_23083294_5_1 772-791 expanded denotes confidence interval
SS2_23083294_5_1 793-795 abbr denotes CI
AE1_23083294_1_0 SS1_23083294_1_0 SS2_23083294_1_0 abbreviatedTo genome-wide association study,GWAS
AE1_23083294_1_1 SS1_23083294_1_1 SS2_23083294_1_1 abbreviatedTo human leukocyte antigen,HLA
AE1_23083294_1_2 SS1_23083294_1_2 SS2_23083294_1_2 abbreviatedTo Parkinson's disease,PD
AE1_23083294_5_0 SS1_23083294_5_0 SS2_23083294_5_0 abbreviatedTo odds ratio,OR
AE1_23083294_5_1 SS1_23083294_5_1 SS2_23083294_5_1 abbreviatedTo confidence interval,CI

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 246-255 HP_0001300 denotes Parkinson

DisGeNET5_variant_disease

Id Subject Object Predicate Lexical cue
23083294-1#11#20#geners3129882 68-77 geners3129882 denotes rs3129882
23083294-1#189#208#diseaseC0030567 246-265 diseaseC0030567 denotes Parkinson's disease
23083294-1#210#212#diseaseC0030567 267-269 diseaseC0030567 denotes PD
11#20#geners3129882189#208#diseaseC0030567 23083294-1#11#20#geners3129882 23083294-1#189#208#diseaseC0030567 associated_with rs3129882,Parkinson's disease
11#20#geners3129882210#212#diseaseC0030567 23083294-1#11#20#geners3129882 23083294-1#210#212#diseaseC0030567 associated_with rs3129882,PD

PubTator4TogoVar

Id Subject Object Predicate Lexical cue resolved_to
17 68-77 SNP denotes rs3129882 tmVar:rs3129882;VariantGroup:0;CorrespondingGene:3122;RS#:3129882;CorrespondingSpecies:9606
22 360-369 SNP denotes rs3129882 tmVar:rs3129882;VariantGroup:0;CorrespondingGene:3122;RS#:3129882;CorrespondingSpecies:9606
24 499-508 SNP denotes rs3129882 tmVar:rs3129882;VariantGroup:0;CorrespondingGene:3122;RS#:3129882;CorrespondingSpecies:9606

PubTatorOnTogoVar

Id Subject Object Predicate Lexical cue resolved_to
17 68-77 SNP denotes rs3129882 tmVar:rs3129882;VariantGroup:0;CorrespondingGene:3122;RS#:3129882;CorrespondingSpecies:9606
22 360-369 SNP denotes rs3129882 tmVar:rs3129882;VariantGroup:0;CorrespondingGene:3122;RS#:3129882;CorrespondingSpecies:9606
24 499-508 SNP denotes rs3129882 tmVar:rs3129882;VariantGroup:0;CorrespondingGene:3122;RS#:3129882;CorrespondingSpecies:9606
T1 68-77 SNP denotes rs3129882 tmVar:rs3129882;VariantGroup:0;CorrespondingGene:3122;RS#:3129882;CorrespondingSpecies:9606
T2 360-369 SNP denotes rs3129882 tmVar:rs3129882;VariantGroup:0;CorrespondingGene:3122;RS#:3129882;CorrespondingSpecies:9606
T3 499-508 SNP denotes rs3129882 tmVar:rs3129882;VariantGroup:0;CorrespondingGene:3122;RS#:3129882;CorrespondingSpecies:9606