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PubMed:22752006 JSONTXT

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Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 656-664 http://purl.obolibrary.org/obo/MAT_0000279 denotes placenta

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-95 Sentence denotes Galectin-1 confers immune privilege to human trophoblast: implications in recurrent fetal loss.
TextSentencer_T2 96-223 Sentence denotes Mechanisms accounting for the protection of the fetal semi-allograft from maternal immune cells remain incompletely understood.
TextSentencer_T3 224-415 Sentence denotes In previous studies, we showed that galectin-1 (Gal1), an immunoregulatory glycan-binding protein, hierarchically triggers a cascade of tolerogenic events at the mouse fetomaternal interface.
TextSentencer_T4 416-552 Sentence denotes Here, we show that Gal1 confers immune privilege to human trophoblast cells through the modulation of a number of regulatory mechanisms.
TextSentencer_T5 553-704 Sentence denotes Gal1 was mainly expressed in invasive extravillous trophoblast cells of human first trimester and term placenta in direct contact with maternal tissue.
TextSentencer_T6 705-1025 Sentence denotes Expression of Gal1 by the human trophoblast cell line JEG-3 was primarily controlled by progesterone and pro-inflammatory cytokines and impaired T-cell responses by limiting T cell viability, suppressing the secretion of Th1-type cytokines and favoring the expansion of CD4(+)CD25(+)FoxP3(+) regulatory T (T(reg)) cells.
TextSentencer_T7 1026-1233 Sentence denotes Targeted inhibition of Gal1 expression through antibody (Ab)-mediated blockade, addition of the specific disaccharide lactose or retroviral-mediated siRNA strategies prevented these immunoregulatory effects.
TextSentencer_T8 1234-1470 Sentence denotes Consistent with a homeostatic role of endogenous Gal1, patients with recurrent pregnancy loss showed considerably lower levels of circulating Gal1 and had higher frequency of anti-Gal1 auto-Abs in their sera compared with fertile women.
TextSentencer_T9 1471-1641 Sentence denotes Thus, endogenous Gal1 confers immune privilege to human trophoblast cells by triggering a broad tolerogenic program with potential implications in threatened pregnancies.
T1 0-95 Sentence denotes Galectin-1 confers immune privilege to human trophoblast: implications in recurrent fetal loss.
T2 96-223 Sentence denotes Mechanisms accounting for the protection of the fetal semi-allograft from maternal immune cells remain incompletely understood.
T3 224-415 Sentence denotes In previous studies, we showed that galectin-1 (Gal1), an immunoregulatory glycan-binding protein, hierarchically triggers a cascade of tolerogenic events at the mouse fetomaternal interface.
T4 416-552 Sentence denotes Here, we show that Gal1 confers immune privilege to human trophoblast cells through the modulation of a number of regulatory mechanisms.
T5 553-704 Sentence denotes Gal1 was mainly expressed in invasive extravillous trophoblast cells of human first trimester and term placenta in direct contact with maternal tissue.
T6 705-1025 Sentence denotes Expression of Gal1 by the human trophoblast cell line JEG-3 was primarily controlled by progesterone and pro-inflammatory cytokines and impaired T-cell responses by limiting T cell viability, suppressing the secretion of Th1-type cytokines and favoring the expansion of CD4(+)CD25(+)FoxP3(+) regulatory T (T(reg)) cells.
T7 1026-1233 Sentence denotes Targeted inhibition of Gal1 expression through antibody (Ab)-mediated blockade, addition of the specific disaccharide lactose or retroviral-mediated siRNA strategies prevented these immunoregulatory effects.
T8 1234-1470 Sentence denotes Consistent with a homeostatic role of endogenous Gal1, patients with recurrent pregnancy loss showed considerably lower levels of circulating Gal1 and had higher frequency of anti-Gal1 auto-Abs in their sera compared with fertile women.
T9 1471-1641 Sentence denotes Thus, endogenous Gal1 confers immune privilege to human trophoblast cells by triggering a broad tolerogenic program with potential implications in threatened pregnancies.
T1 0-95 Sentence denotes Galectin-1 confers immune privilege to human trophoblast: implications in recurrent fetal loss.
T2 96-223 Sentence denotes Mechanisms accounting for the protection of the fetal semi-allograft from maternal immune cells remain incompletely understood.
T3 224-415 Sentence denotes In previous studies, we showed that galectin-1 (Gal1), an immunoregulatory glycan-binding protein, hierarchically triggers a cascade of tolerogenic events at the mouse fetomaternal interface.
T4 416-552 Sentence denotes Here, we show that Gal1 confers immune privilege to human trophoblast cells through the modulation of a number of regulatory mechanisms.
T5 553-704 Sentence denotes Gal1 was mainly expressed in invasive extravillous trophoblast cells of human first trimester and term placenta in direct contact with maternal tissue.
T6 705-1025 Sentence denotes Expression of Gal1 by the human trophoblast cell line JEG-3 was primarily controlled by progesterone and pro-inflammatory cytokines and impaired T-cell responses by limiting T cell viability, suppressing the secretion of Th1-type cytokines and favoring the expansion of CD4(+)CD25(+)FoxP3(+) regulatory T (T(reg)) cells.
T7 1026-1233 Sentence denotes Targeted inhibition of Gal1 expression through antibody (Ab)-mediated blockade, addition of the specific disaccharide lactose or retroviral-mediated siRNA strategies prevented these immunoregulatory effects.
T8 1234-1470 Sentence denotes Consistent with a homeostatic role of endogenous Gal1, patients with recurrent pregnancy loss showed considerably lower levels of circulating Gal1 and had higher frequency of anti-Gal1 auto-Abs in their sera compared with fertile women.
T9 1471-1641 Sentence denotes Thus, endogenous Gal1 confers immune privilege to human trophoblast cells by triggering a broad tolerogenic program with potential implications in threatened pregnancies.

GlycoBiology-FMA

Id Subject Object Predicate Lexical cue
_T1 45-56 FMAID:83029 denotes trophoblast
_T2 45-56 FMAID:197289 denotes trophoblast
_T3 186-191 FMAID:169002 denotes cells
_T4 186-191 FMAID:68646 denotes cells
_T5 314-321 FMAID:165447 denotes protein
_T6 314-321 FMAID:67257 denotes protein
_T7 474-485 FMAID:83029 denotes trophoblast
_T8 474-485 FMAID:197289 denotes trophoblast
_T9 474-491 FMAID:202194 denotes trophoblast cells
_T10 474-491 FMAID:83028 denotes trophoblast cells
_T11 474-491 FMAID:200947 denotes trophoblast cells
_T12 474-491 FMAID:197288 denotes trophoblast cells
_T13 486-491 FMAID:169002 denotes cells
_T14 486-491 FMAID:68646 denotes cells
_T15 604-615 FMAID:197289 denotes trophoblast
_T16 604-615 FMAID:83029 denotes trophoblast
_T17 604-621 FMAID:202194 denotes trophoblast cells
_T18 604-621 FMAID:83028 denotes trophoblast cells
_T19 604-621 FMAID:200947 denotes trophoblast cells
_T20 604-621 FMAID:197288 denotes trophoblast cells
_T21 616-621 FMAID:68646 denotes cells
_T22 616-621 FMAID:169002 denotes cells
_T23 656-664 FMAID:63934 denotes placenta
_T24 656-664 FMAID:162401 denotes placenta
_T25 697-703 FMAID:256050 denotes tissue
_T26 737-748 FMAID:197289 denotes trophoblast
_T27 737-748 FMAID:83029 denotes trophoblast
_T28 737-753 FMAID:200947 denotes trophoblast cell
_T29 737-753 FMAID:202194 denotes trophoblast cell
_T30 737-753 FMAID:83028 denotes trophoblast cell
_T31 737-753 FMAID:197288 denotes trophoblast cell
_T32 827-836 FMAID:197972 denotes cytokines
_T33 827-836 FMAID:84050 denotes cytokines
_T34 935-944 FMAID:197972 denotes cytokines
_T35 935-944 FMAID:84050 denotes cytokines
_T36 1019-1024 FMAID:68646 denotes cells
_T37 1019-1024 FMAID:169002 denotes cells
_T38 1073-1081 FMAID:167180 denotes antibody
_T39 1131-1143 FMAID:196733 denotes disaccharide
_T40 1131-1143 FMAID:82744 denotes disaccharide
_T41 1527-1538 FMAID:197289 denotes trophoblast
_T42 1527-1538 FMAID:83029 denotes trophoblast
_T43 1527-1544 FMAID:197288 denotes trophoblast cells
_T44 1527-1544 FMAID:200947 denotes trophoblast cells
_T45 1527-1544 FMAID:83028 denotes trophoblast cells
_T46 1527-1544 FMAID:202194 denotes trophoblast cells
_T47 1539-1544 FMAID:68646 denotes cells
_T48 1539-1544 FMAID:169002 denotes cells

uniprot-human

Id Subject Object Predicate Lexical cue
T1 0-10 http://www.uniprot.org/uniprot/P09382 denotes Galectin-1
T2 260-270 http://www.uniprot.org/uniprot/P09382 denotes galectin-1
T3 975-978 http://www.uniprot.org/uniprot/P01730 denotes CD4
T4 981-985 http://www.uniprot.org/uniprot/P01589 denotes CD25

uniprot-mouse

Id Subject Object Predicate Lexical cue
T1 0-10 http://www.uniprot.org/uniprot/P16045 denotes Galectin-1
T2 260-270 http://www.uniprot.org/uniprot/P16045 denotes galectin-1
T3 810-813 http://www.uniprot.org/uniprot/Q08761 denotes pro
T4 926-929 http://www.uniprot.org/uniprot/Q64279 denotes Th1
T5 926-929 http://www.uniprot.org/uniprot/Q922L6 denotes Th1
T6 975-978 http://www.uniprot.org/uniprot/P06332 denotes CD4
T7 981-985 http://www.uniprot.org/uniprot/P01590 denotes CD25

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 96-106 http://purl.bioontology.org/ontology/NCBITAXON/127244 denotes Mechanisms
T2 186-191 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T3 372-378 http://purl.bioontology.org/ontology/STY/T051 denotes events
T4 486-491 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T5 541-551 http://purl.bioontology.org/ontology/NCBITAXON/127244 denotes mechanisms
T6 616-621 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T7 651-655 http://purl.bioontology.org/ontology/NCBITAXON/62951 denotes term
T8 697-703 http://purl.bioontology.org/ontology/STY/T024 denotes tissue
T9 1019-1024 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T10 1539-1544 http://purl.bioontology.org/ontology/STY/T025 denotes cells

GO-BP

Id Subject Object Predicate Lexical cue
T1 913-922 http://purl.obolibrary.org/obo/GO_0046903 denotes secretion
T2 1437-1441 http://purl.obolibrary.org/obo/GO_0004617 denotes sera
T3 1456-1463 http://purl.obolibrary.org/obo/GO_0009566 denotes fertile

GO-MF

Id Subject Object Predicate Lexical cue
T1 306-313 http://purl.obolibrary.org/obo/GO_0070026 denotes binding
T2 306-313 http://purl.obolibrary.org/obo/GO_0003680 denotes binding
T3 306-313 http://purl.obolibrary.org/obo/GO_0017091 denotes binding
T4 306-313 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T5 306-321 http://purl.obolibrary.org/obo/GO_0005515 denotes binding protein
T6 1073-1081 http://purl.obolibrary.org/obo/GO_0003823 denotes antibody

GO-CC

Id Subject Object Predicate Lexical cue
T1 186-191 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T2 486-491 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T3 616-621 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T4 1019-1024 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T5 749-753 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T6 852-856 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T7 881-885 http://purl.obolibrary.org/obo/GO_0005623 denotes cell

UBERON-AE

Id Subject Object Predicate Lexical cue
T1 45-56 http://purl.obolibrary.org/obo/UBERON_0000088 denotes trophoblast
T2 474-485 http://purl.obolibrary.org/obo/UBERON_0000088 denotes trophoblast
T3 604-615 http://purl.obolibrary.org/obo/UBERON_0000088 denotes trophoblast
T4 737-748 http://purl.obolibrary.org/obo/UBERON_0000088 denotes trophoblast
T5 1527-1538 http://purl.obolibrary.org/obo/UBERON_0000088 denotes trophoblast
T6 591-615 http://purl.obolibrary.org/obo/UBERON_0000426 denotes extravillous trophoblast
T7 656-664 http://purl.obolibrary.org/obo/UBERON_0001987 denotes placenta
T8 697-703 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissue

Allie

Id Subject Object Predicate Lexical cue
SS1_22752006_2_0 260-270 expanded denotes galectin-1
SS2_22752006_2_0 272-276 abbr denotes Gal1
SS1_22752006_6_0 1073-1081 expanded denotes antibody
SS2_22752006_6_0 1083-1085 abbr denotes Ab
AE1_22752006_2_0 SS1_22752006_2_0 SS2_22752006_2_0 abbreviatedTo galectin-1,Gal1
AE1_22752006_6_0 SS1_22752006_6_0 SS2_22752006_6_0 abbreviatedTo antibody,Ab

GlyTouCan-IUPAC

Id Subject Object Predicate Lexical cue
GlycanIUPAC_T1 269-276 "http://rdf.glycoinfo.org/glycan/G04340UO" denotes 1 (Gal1
GlycanIUPAC_T2 269-276 "http://rdf.glycoinfo.org/glycan/G79992SX" denotes 1 (Gal1
GlycanIUPAC_T3 269-276 "http://rdf.glycoinfo.org/glycan/G20773IW" denotes 1 (Gal1
GlycanIUPAC_T4 269-276 "http://rdf.glycoinfo.org/glycan/G61666PA" denotes 1 (Gal1
GlycanIUPAC_T5 269-276 "http://rdf.glycoinfo.org/glycan/G98350CS" denotes 1 (Gal1
GlycanIUPAC_T6 269-276 "http://rdf.glycoinfo.org/glycan/G26289JC" denotes 1 (Gal1
GlycanIUPAC_T7 269-276 "http://rdf.glycoinfo.org/glycan/G01753HF" denotes 1 (Gal1
GlycanIUPAC_T8 269-276 "http://rdf.glycoinfo.org/glycan/G25061NQ" denotes 1 (Gal1
GlycanIUPAC_T9 269-276 "http://rdf.glycoinfo.org/glycan/G91444NO" denotes 1 (Gal1
GlycanIUPAC_T10 272-276 "http://rdf.glycoinfo.org/glycan/G32871SU" denotes Gal1
GlycanIUPAC_T11 435-439 "http://rdf.glycoinfo.org/glycan/G32871SU" denotes Gal1
GlycanIUPAC_T12 553-557 "http://rdf.glycoinfo.org/glycan/G32871SU" denotes Gal1
GlycanIUPAC_T13 719-723 "http://rdf.glycoinfo.org/glycan/G32871SU" denotes Gal1
GlycanIUPAC_T14 1049-1053 "http://rdf.glycoinfo.org/glycan/G32871SU" denotes Gal1
GlycanIUPAC_T15 1283-1287 "http://rdf.glycoinfo.org/glycan/G32871SU" denotes Gal1
GlycanIUPAC_T16 1376-1380 "http://rdf.glycoinfo.org/glycan/G32871SU" denotes Gal1
GlycanIUPAC_T17 1414-1418 "http://rdf.glycoinfo.org/glycan/G32871SU" denotes Gal1
GlycanIUPAC_T18 1488-1492 "http://rdf.glycoinfo.org/glycan/G32871SU" denotes Gal1
GlycanIUPAC_T19 272-276 "http://rdf.glycoinfo.org/glycan/G07087RJ" denotes Gal1
GlycanIUPAC_T20 435-439 "http://rdf.glycoinfo.org/glycan/G07087RJ" denotes Gal1
GlycanIUPAC_T21 553-557 "http://rdf.glycoinfo.org/glycan/G07087RJ" denotes Gal1
GlycanIUPAC_T22 719-723 "http://rdf.glycoinfo.org/glycan/G07087RJ" denotes Gal1
GlycanIUPAC_T23 1049-1053 "http://rdf.glycoinfo.org/glycan/G07087RJ" denotes Gal1
GlycanIUPAC_T24 1283-1287 "http://rdf.glycoinfo.org/glycan/G07087RJ" denotes Gal1
GlycanIUPAC_T25 1376-1380 "http://rdf.glycoinfo.org/glycan/G07087RJ" denotes Gal1
GlycanIUPAC_T26 1414-1418 "http://rdf.glycoinfo.org/glycan/G07087RJ" denotes Gal1
GlycanIUPAC_T27 1488-1492 "http://rdf.glycoinfo.org/glycan/G07087RJ" denotes Gal1
GlycanIUPAC_T28 272-276 "http://rdf.glycoinfo.org/glycan/G40843KY" denotes Gal1
GlycanIUPAC_T29 435-439 "http://rdf.glycoinfo.org/glycan/G40843KY" denotes Gal1
GlycanIUPAC_T30 553-557 "http://rdf.glycoinfo.org/glycan/G40843KY" denotes Gal1
GlycanIUPAC_T31 719-723 "http://rdf.glycoinfo.org/glycan/G40843KY" denotes Gal1
GlycanIUPAC_T32 1049-1053 "http://rdf.glycoinfo.org/glycan/G40843KY" denotes Gal1
GlycanIUPAC_T33 1283-1287 "http://rdf.glycoinfo.org/glycan/G40843KY" denotes Gal1
GlycanIUPAC_T34 1376-1380 "http://rdf.glycoinfo.org/glycan/G40843KY" denotes Gal1
GlycanIUPAC_T35 1414-1418 "http://rdf.glycoinfo.org/glycan/G40843KY" denotes Gal1
GlycanIUPAC_T36 1488-1492 "http://rdf.glycoinfo.org/glycan/G40843KY" denotes Gal1
GlycanIUPAC_T37 272-276 "http://rdf.glycoinfo.org/glycan/G68158BT" denotes Gal1
GlycanIUPAC_T38 435-439 "http://rdf.glycoinfo.org/glycan/G68158BT" denotes Gal1
GlycanIUPAC_T39 553-557 "http://rdf.glycoinfo.org/glycan/G68158BT" denotes Gal1
GlycanIUPAC_T40 719-723 "http://rdf.glycoinfo.org/glycan/G68158BT" denotes Gal1
GlycanIUPAC_T41 1049-1053 "http://rdf.glycoinfo.org/glycan/G68158BT" denotes Gal1
GlycanIUPAC_T42 1283-1287 "http://rdf.glycoinfo.org/glycan/G68158BT" denotes Gal1
GlycanIUPAC_T43 1376-1380 "http://rdf.glycoinfo.org/glycan/G68158BT" denotes Gal1
GlycanIUPAC_T44 1414-1418 "http://rdf.glycoinfo.org/glycan/G68158BT" denotes Gal1
GlycanIUPAC_T45 1488-1492 "http://rdf.glycoinfo.org/glycan/G68158BT" denotes Gal1
GlycanIUPAC_T46 272-276 "http://rdf.glycoinfo.org/glycan/G75623HL" denotes Gal1
GlycanIUPAC_T47 435-439 "http://rdf.glycoinfo.org/glycan/G75623HL" denotes Gal1
GlycanIUPAC_T48 553-557 "http://rdf.glycoinfo.org/glycan/G75623HL" denotes Gal1
GlycanIUPAC_T49 719-723 "http://rdf.glycoinfo.org/glycan/G75623HL" denotes Gal1
GlycanIUPAC_T50 1049-1053 "http://rdf.glycoinfo.org/glycan/G75623HL" denotes Gal1
GlycanIUPAC_T51 1283-1287 "http://rdf.glycoinfo.org/glycan/G75623HL" denotes Gal1
GlycanIUPAC_T52 1376-1380 "http://rdf.glycoinfo.org/glycan/G75623HL" denotes Gal1
GlycanIUPAC_T53 1414-1418 "http://rdf.glycoinfo.org/glycan/G75623HL" denotes Gal1
GlycanIUPAC_T54 1488-1492 "http://rdf.glycoinfo.org/glycan/G75623HL" denotes Gal1
GlycanIUPAC_T55 272-276 "http://rdf.glycoinfo.org/glycan/G08908FU" denotes Gal1
GlycanIUPAC_T56 435-439 "http://rdf.glycoinfo.org/glycan/G08908FU" denotes Gal1
GlycanIUPAC_T57 553-557 "http://rdf.glycoinfo.org/glycan/G08908FU" denotes Gal1
GlycanIUPAC_T58 719-723 "http://rdf.glycoinfo.org/glycan/G08908FU" denotes Gal1
GlycanIUPAC_T59 1049-1053 "http://rdf.glycoinfo.org/glycan/G08908FU" denotes Gal1
GlycanIUPAC_T60 1283-1287 "http://rdf.glycoinfo.org/glycan/G08908FU" denotes Gal1
GlycanIUPAC_T61 1376-1380 "http://rdf.glycoinfo.org/glycan/G08908FU" denotes Gal1
GlycanIUPAC_T62 1414-1418 "http://rdf.glycoinfo.org/glycan/G08908FU" denotes Gal1
GlycanIUPAC_T63 1488-1492 "http://rdf.glycoinfo.org/glycan/G08908FU" denotes Gal1
GlycanIUPAC_T64 272-276 "http://rdf.glycoinfo.org/glycan/G38028NH" denotes Gal1
GlycanIUPAC_T65 435-439 "http://rdf.glycoinfo.org/glycan/G38028NH" denotes Gal1
GlycanIUPAC_T66 553-557 "http://rdf.glycoinfo.org/glycan/G38028NH" denotes Gal1
GlycanIUPAC_T67 719-723 "http://rdf.glycoinfo.org/glycan/G38028NH" denotes Gal1
GlycanIUPAC_T68 1049-1053 "http://rdf.glycoinfo.org/glycan/G38028NH" denotes Gal1
GlycanIUPAC_T69 1283-1287 "http://rdf.glycoinfo.org/glycan/G38028NH" denotes Gal1
GlycanIUPAC_T70 1376-1380 "http://rdf.glycoinfo.org/glycan/G38028NH" denotes Gal1
GlycanIUPAC_T71 1414-1418 "http://rdf.glycoinfo.org/glycan/G38028NH" denotes Gal1
GlycanIUPAC_T72 1488-1492 "http://rdf.glycoinfo.org/glycan/G38028NH" denotes Gal1
GlycanIUPAC_T73 272-276 "http://rdf.glycoinfo.org/glycan/G48426CT" denotes Gal1
GlycanIUPAC_T74 435-439 "http://rdf.glycoinfo.org/glycan/G48426CT" denotes Gal1
GlycanIUPAC_T75 553-557 "http://rdf.glycoinfo.org/glycan/G48426CT" denotes Gal1
GlycanIUPAC_T76 719-723 "http://rdf.glycoinfo.org/glycan/G48426CT" denotes Gal1
GlycanIUPAC_T77 1049-1053 "http://rdf.glycoinfo.org/glycan/G48426CT" denotes Gal1
GlycanIUPAC_T78 1283-1287 "http://rdf.glycoinfo.org/glycan/G48426CT" denotes Gal1
GlycanIUPAC_T79 1376-1380 "http://rdf.glycoinfo.org/glycan/G48426CT" denotes Gal1
GlycanIUPAC_T80 1414-1418 "http://rdf.glycoinfo.org/glycan/G48426CT" denotes Gal1
GlycanIUPAC_T81 1488-1492 "http://rdf.glycoinfo.org/glycan/G48426CT" denotes Gal1
GlycanIUPAC_T82 272-276 "http://rdf.glycoinfo.org/glycan/G34526ZS" denotes Gal1
GlycanIUPAC_T83 435-439 "http://rdf.glycoinfo.org/glycan/G34526ZS" denotes Gal1
GlycanIUPAC_T84 553-557 "http://rdf.glycoinfo.org/glycan/G34526ZS" denotes Gal1
GlycanIUPAC_T85 719-723 "http://rdf.glycoinfo.org/glycan/G34526ZS" denotes Gal1
GlycanIUPAC_T86 1049-1053 "http://rdf.glycoinfo.org/glycan/G34526ZS" denotes Gal1
GlycanIUPAC_T87 1283-1287 "http://rdf.glycoinfo.org/glycan/G34526ZS" denotes Gal1
GlycanIUPAC_T88 1376-1380 "http://rdf.glycoinfo.org/glycan/G34526ZS" denotes Gal1
GlycanIUPAC_T89 1414-1418 "http://rdf.glycoinfo.org/glycan/G34526ZS" denotes Gal1
GlycanIUPAC_T90 1488-1492 "http://rdf.glycoinfo.org/glycan/G34526ZS" denotes Gal1
GlycanIUPAC_T91 272-276 "http://rdf.glycoinfo.org/glycan/G25681JY" denotes Gal1
GlycanIUPAC_T92 435-439 "http://rdf.glycoinfo.org/glycan/G25681JY" denotes Gal1
GlycanIUPAC_T93 553-557 "http://rdf.glycoinfo.org/glycan/G25681JY" denotes Gal1
GlycanIUPAC_T94 719-723 "http://rdf.glycoinfo.org/glycan/G25681JY" denotes Gal1
GlycanIUPAC_T95 1049-1053 "http://rdf.glycoinfo.org/glycan/G25681JY" denotes Gal1
GlycanIUPAC_T96 1283-1287 "http://rdf.glycoinfo.org/glycan/G25681JY" denotes Gal1
GlycanIUPAC_T97 1376-1380 "http://rdf.glycoinfo.org/glycan/G25681JY" denotes Gal1
GlycanIUPAC_T98 1414-1418 "http://rdf.glycoinfo.org/glycan/G25681JY" denotes Gal1
GlycanIUPAC_T99 1488-1492 "http://rdf.glycoinfo.org/glycan/G25681JY" denotes Gal1
GlycanIUPAC_T100 272-276 "http://rdf.glycoinfo.org/glycan/G75236KD" denotes Gal1
GlycanIUPAC_T101 435-439 "http://rdf.glycoinfo.org/glycan/G75236KD" denotes Gal1
GlycanIUPAC_T102 553-557 "http://rdf.glycoinfo.org/glycan/G75236KD" denotes Gal1
GlycanIUPAC_T103 719-723 "http://rdf.glycoinfo.org/glycan/G75236KD" denotes Gal1
GlycanIUPAC_T104 1049-1053 "http://rdf.glycoinfo.org/glycan/G75236KD" denotes Gal1
GlycanIUPAC_T105 1283-1287 "http://rdf.glycoinfo.org/glycan/G75236KD" denotes Gal1
GlycanIUPAC_T106 1376-1380 "http://rdf.glycoinfo.org/glycan/G75236KD" denotes Gal1
GlycanIUPAC_T107 1414-1418 "http://rdf.glycoinfo.org/glycan/G75236KD" denotes Gal1
GlycanIUPAC_T108 1488-1492 "http://rdf.glycoinfo.org/glycan/G75236KD" denotes Gal1

GlycoBiology-MAT

Id Subject Object Predicate Lexical cue
T1 656-664 http://purl.obolibrary.org/obo/MAT_0000279 denotes placenta

Lectin

Id Subject Object Predicate Lexical cue
Lectin_T1 0-8 https://acgg.asia/db/lfdb/LfDB0272 denotes Galectin
Lectin_T2 0-10 https://acgg.asia/db/lfdb/LfDB0270 denotes Galectin-1
Lectin_T3 260-270 https://acgg.asia/db/lfdb/LfDB0270 denotes galectin-1
Lectin_T4 0-8 https://acgg.asia/db/lfdb/LfDB0274 denotes Galectin
Lectin_T5 0-10 https://acgg.asia/db/lfdb/LfDB0057 denotes Galectin-1
Lectin_T6 260-270 https://acgg.asia/db/lfdb/LfDB0057 denotes galectin-1

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 697-703 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissue
PD-UBERON-AE-B_T2 656-664 http://purl.obolibrary.org/obo/UBERON_0001987 denotes placenta
PD-UBERON-AE-B_T3 45-56 http://purl.obolibrary.org/obo/UBERON_0000088 denotes trophoblast
PD-UBERON-AE-B_T4 474-485 http://purl.obolibrary.org/obo/UBERON_0000088 denotes trophoblast
PD-UBERON-AE-B_T5 604-615 http://purl.obolibrary.org/obo/UBERON_0000088 denotes trophoblast
PD-UBERON-AE-B_T6 737-748 http://purl.obolibrary.org/obo/UBERON_0000088 denotes trophoblast
PD-UBERON-AE-B_T7 1527-1538 http://purl.obolibrary.org/obo/UBERON_0000088 denotes trophoblast
PD-UBERON-AE-B_T8 591-615 http://purl.obolibrary.org/obo/UBERON_0000426 denotes extravillous trophoblast

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 1144-1151 Glycan denotes lactose https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE

GlyCosmos15-NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 39-44 OrganismTaxon denotes human 9606
T2 386-391 OrganismTaxon denotes mouse 10088|10090
T4 468-473 OrganismTaxon denotes human 9606
T5 625-630 OrganismTaxon denotes human 9606
T6 731-736 OrganismTaxon denotes human 9606
T7 1521-1526 OrganismTaxon denotes human 9606

GlyCosmos15-CL

Id Subject Object Predicate Lexical cue cl_id
T1 179-191 Cell denotes immune cells http://purl.obolibrary.org/obo/CL:0000738
T2 474-491 Cell denotes trophoblast cells http://purl.obolibrary.org/obo/CL:0000351
T3 591-615 Cell denotes extravillous trophoblast http://purl.obolibrary.org/obo/CL:0008036
T4 737-753 Cell denotes trophoblast cell http://purl.obolibrary.org/obo/CL:0000351
T5 850-856 Cell denotes T-cell http://purl.obolibrary.org/obo/CL:0000084
T6 879-885 Cell denotes T cell http://purl.obolibrary.org/obo/CL:0000084
T7 1011-1017 Cell denotes T(reg) http://purl.obolibrary.org/obo/CL:0000792|http://purl.obolibrary.org/obo/CL:0000815
T9 1527-1544 Cell denotes trophoblast cells http://purl.obolibrary.org/obo/CL:0000351

GlyCosmos15-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 45-56 Body_part denotes trophoblast http://purl.obolibrary.org/obo/UBERON_0000088
T2 179-191 Body_part denotes immune cells http://purl.obolibrary.org/obo/CL_0000738
T3 474-491 Body_part denotes trophoblast cells http://purl.obolibrary.org/obo/CL_0000351
T4 591-615 Body_part denotes extravillous trophoblast http://purl.obolibrary.org/obo/UBERON_0000426
T5 656-664 Body_part denotes placenta http://purl.obolibrary.org/obo/UBERON_0001987
T6 697-703 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T7 737-753 Body_part denotes trophoblast cell http://purl.obolibrary.org/obo/CL_0000351
T8 850-856 Body_part denotes T-cell http://purl.obolibrary.org/obo/CL_0000084
T9 879-885 Body_part denotes T cell http://purl.obolibrary.org/obo/CL_0000084
T10 1527-1544 Body_part denotes trophoblast cells http://purl.obolibrary.org/obo/CL_0000351

GlyCosmos15-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 656-664 Body_part denotes placenta http://purl.obolibrary.org/obo/MAT_0000279

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-95 Sentence denotes Galectin-1 confers immune privilege to human trophoblast: implications in recurrent fetal loss.
TextSentencer_T2 96-223 Sentence denotes Mechanisms accounting for the protection of the fetal semi-allograft from maternal immune cells remain incompletely understood.
TextSentencer_T3 224-415 Sentence denotes In previous studies, we showed that galectin-1 (Gal1), an immunoregulatory glycan-binding protein, hierarchically triggers a cascade of tolerogenic events at the mouse fetomaternal interface.
TextSentencer_T4 416-552 Sentence denotes Here, we show that Gal1 confers immune privilege to human trophoblast cells through the modulation of a number of regulatory mechanisms.
TextSentencer_T5 553-704 Sentence denotes Gal1 was mainly expressed in invasive extravillous trophoblast cells of human first trimester and term placenta in direct contact with maternal tissue.
TextSentencer_T6 705-1025 Sentence denotes Expression of Gal1 by the human trophoblast cell line JEG-3 was primarily controlled by progesterone and pro-inflammatory cytokines and impaired T-cell responses by limiting T cell viability, suppressing the secretion of Th1-type cytokines and favoring the expansion of CD4(+)CD25(+)FoxP3(+) regulatory T (T(reg)) cells.
TextSentencer_T7 1026-1233 Sentence denotes Targeted inhibition of Gal1 expression through antibody (Ab)-mediated blockade, addition of the specific disaccharide lactose or retroviral-mediated siRNA strategies prevented these immunoregulatory effects.
TextSentencer_T8 1234-1470 Sentence denotes Consistent with a homeostatic role of endogenous Gal1, patients with recurrent pregnancy loss showed considerably lower levels of circulating Gal1 and had higher frequency of anti-Gal1 auto-Abs in their sera compared with fertile women.
TextSentencer_T9 1471-1641 Sentence denotes Thus, endogenous Gal1 confers immune privilege to human trophoblast cells by triggering a broad tolerogenic program with potential implications in threatened pregnancies.
T1 0-95 Sentence denotes Galectin-1 confers immune privilege to human trophoblast: implications in recurrent fetal loss.
T2 96-223 Sentence denotes Mechanisms accounting for the protection of the fetal semi-allograft from maternal immune cells remain incompletely understood.
T3 224-415 Sentence denotes In previous studies, we showed that galectin-1 (Gal1), an immunoregulatory glycan-binding protein, hierarchically triggers a cascade of tolerogenic events at the mouse fetomaternal interface.
T4 416-552 Sentence denotes Here, we show that Gal1 confers immune privilege to human trophoblast cells through the modulation of a number of regulatory mechanisms.
T5 553-704 Sentence denotes Gal1 was mainly expressed in invasive extravillous trophoblast cells of human first trimester and term placenta in direct contact with maternal tissue.
T6 705-1025 Sentence denotes Expression of Gal1 by the human trophoblast cell line JEG-3 was primarily controlled by progesterone and pro-inflammatory cytokines and impaired T-cell responses by limiting T cell viability, suppressing the secretion of Th1-type cytokines and favoring the expansion of CD4(+)CD25(+)FoxP3(+) regulatory T (T(reg)) cells.
T7 1026-1233 Sentence denotes Targeted inhibition of Gal1 expression through antibody (Ab)-mediated blockade, addition of the specific disaccharide lactose or retroviral-mediated siRNA strategies prevented these immunoregulatory effects.
T8 1234-1470 Sentence denotes Consistent with a homeostatic role of endogenous Gal1, patients with recurrent pregnancy loss showed considerably lower levels of circulating Gal1 and had higher frequency of anti-Gal1 auto-Abs in their sera compared with fertile women.
T9 1471-1641 Sentence denotes Thus, endogenous Gal1 confers immune privilege to human trophoblast cells by triggering a broad tolerogenic program with potential implications in threatened pregnancies.
T1 0-95 Sentence denotes Galectin-1 confers immune privilege to human trophoblast: implications in recurrent fetal loss.
T2 96-223 Sentence denotes Mechanisms accounting for the protection of the fetal semi-allograft from maternal immune cells remain incompletely understood.
T3 224-415 Sentence denotes In previous studies, we showed that galectin-1 (Gal1), an immunoregulatory glycan-binding protein, hierarchically triggers a cascade of tolerogenic events at the mouse fetomaternal interface.
T4 416-552 Sentence denotes Here, we show that Gal1 confers immune privilege to human trophoblast cells through the modulation of a number of regulatory mechanisms.
T5 553-704 Sentence denotes Gal1 was mainly expressed in invasive extravillous trophoblast cells of human first trimester and term placenta in direct contact with maternal tissue.
T6 705-1025 Sentence denotes Expression of Gal1 by the human trophoblast cell line JEG-3 was primarily controlled by progesterone and pro-inflammatory cytokines and impaired T-cell responses by limiting T cell viability, suppressing the secretion of Th1-type cytokines and favoring the expansion of CD4(+)CD25(+)FoxP3(+) regulatory T (T(reg)) cells.
T7 1026-1233 Sentence denotes Targeted inhibition of Gal1 expression through antibody (Ab)-mediated blockade, addition of the specific disaccharide lactose or retroviral-mediated siRNA strategies prevented these immunoregulatory effects.
T8 1234-1470 Sentence denotes Consistent with a homeostatic role of endogenous Gal1, patients with recurrent pregnancy loss showed considerably lower levels of circulating Gal1 and had higher frequency of anti-Gal1 auto-Abs in their sera compared with fertile women.
T9 1471-1641 Sentence denotes Thus, endogenous Gal1 confers immune privilege to human trophoblast cells by triggering a broad tolerogenic program with potential implications in threatened pregnancies.

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-95 Sentence denotes Galectin-1 confers immune privilege to human trophoblast: implications in recurrent fetal loss.
T2 96-223 Sentence denotes Mechanisms accounting for the protection of the fetal semi-allograft from maternal immune cells remain incompletely understood.
T3 224-415 Sentence denotes In previous studies, we showed that galectin-1 (Gal1), an immunoregulatory glycan-binding protein, hierarchically triggers a cascade of tolerogenic events at the mouse fetomaternal interface.
T4 416-552 Sentence denotes Here, we show that Gal1 confers immune privilege to human trophoblast cells through the modulation of a number of regulatory mechanisms.
T5 553-704 Sentence denotes Gal1 was mainly expressed in invasive extravillous trophoblast cells of human first trimester and term placenta in direct contact with maternal tissue.
T6 705-1025 Sentence denotes Expression of Gal1 by the human trophoblast cell line JEG-3 was primarily controlled by progesterone and pro-inflammatory cytokines and impaired T-cell responses by limiting T cell viability, suppressing the secretion of Th1-type cytokines and favoring the expansion of CD4(+)CD25(+)FoxP3(+) regulatory T (T(reg)) cells.
T7 1026-1233 Sentence denotes Targeted inhibition of Gal1 expression through antibody (Ab)-mediated blockade, addition of the specific disaccharide lactose or retroviral-mediated siRNA strategies prevented these immunoregulatory effects.
T8 1234-1470 Sentence denotes Consistent with a homeostatic role of endogenous Gal1, patients with recurrent pregnancy loss showed considerably lower levels of circulating Gal1 and had higher frequency of anti-Gal1 auto-Abs in their sera compared with fertile women.
T9 1471-1641 Sentence denotes Thus, endogenous Gal1 confers immune privilege to human trophoblast cells by triggering a broad tolerogenic program with potential implications in threatened pregnancies.

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 1144-1151 Glycan denotes lactose https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE

GlyCosmos15-Lectin-Jamboree

Id Subject Object Predicate Lexical cue glycosmos_id
T1 0-10 Lectin denotes Galectin-1 GL_001885

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 39-44 OrganismTaxon denotes human 9606
T2 386-391 OrganismTaxon denotes mouse 10088|10090
T4 468-473 OrganismTaxon denotes human 9606
T5 625-630 OrganismTaxon denotes human 9606
T6 731-736 OrganismTaxon denotes human 9606
T7 1521-1526 OrganismTaxon denotes human 9606

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 45-56 Body_part denotes trophoblast http://purl.obolibrary.org/obo/UBERON_0000088
T2 179-191 Body_part denotes immune cells http://purl.obolibrary.org/obo/CL_0000738
T3 474-491 Body_part denotes trophoblast cells http://purl.obolibrary.org/obo/CL_0000351
T4 591-615 Body_part denotes extravillous trophoblast http://purl.obolibrary.org/obo/UBERON_0000426
T5 656-664 Body_part denotes placenta http://purl.obolibrary.org/obo/UBERON_0001987
T6 697-703 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T7 737-753 Body_part denotes trophoblast cell http://purl.obolibrary.org/obo/CL_0000351
T8 850-856 Body_part denotes T-cell http://purl.obolibrary.org/obo/CL_0000084
T9 879-885 Body_part denotes T cell http://purl.obolibrary.org/obo/CL_0000084
T10 1527-1544 Body_part denotes trophoblast cells http://purl.obolibrary.org/obo/CL_0000351

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 656-664 Body_part denotes placenta http://purl.obolibrary.org/obo/MAT_0000279

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 179-191 Cell denotes immune cells http://purl.obolibrary.org/obo/CL:0000738
T2 474-491 Cell denotes trophoblast cells http://purl.obolibrary.org/obo/CL:0000351
T3 591-615 Cell denotes extravillous trophoblast http://purl.obolibrary.org/obo/CL:0008036
T4 737-753 Cell denotes trophoblast cell http://purl.obolibrary.org/obo/CL:0000351
T5 850-856 Cell denotes T-cell http://purl.obolibrary.org/obo/CL:0000084
T6 879-885 Cell denotes T cell http://purl.obolibrary.org/obo/CL:0000084
T7 1011-1017 Cell denotes T(reg) http://purl.obolibrary.org/obo/CL:0000792|http://purl.obolibrary.org/obo/CL:0000815
T9 1527-1544 Cell denotes trophoblast cells http://purl.obolibrary.org/obo/CL:0000351