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PubMed:2193097 JSONTXT

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PubmedHPO

Id Subject Object Predicate Lexical cue
T1 173-189 HP_0002721 denotes immunodeficiency

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 167-250 DNA denotes human immunodeficiency virus type 1-long terminal repeat (HIV-1-LTR) CAT constructs
T2 268-303 cell_line denotes monocyte/macrophage-like cell lines
T3 314-325 cell_line denotes T cell line
T4 387-409 protein denotes nuclear factor kappa B
T5 411-421 protein denotes NF-kappa B
T6 537-547 protein denotes NF-kappa B
T7 551-555 cell_line denotes U937
T8 560-571 cell_line denotes THP-1 cells
T9 640-702 cell_line denotes chronically infected monocyte/macrophage-like cloned cell line
T10 704-706 cell_line denotes U1
T11 861-909 protein denotes granulocyte/macrophage colony-stimulating factor
T12 911-917 protein denotes GM-CSF
T13 1030-1039 RNA denotes HIV-1 RNA
T14 1062-1072 protein denotes NF-kappa B
T15 1129-1140 cell_line denotes T cell line

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-121 Sentence denotes Lipopolysaccharide is a potent monocyte/macrophage-specific stimulator of human immunodeficiency virus type 1 expression.
S2 122-326 Sentence denotes Lipopolysaccharide (LPS) potently stimulates human immunodeficiency virus type 1-long terminal repeat (HIV-1-LTR) CAT constructs transfected into monocyte/macrophage-like cell lines but not a T cell line.
S3 327-423 Sentence denotes This effect appears to be mediated through the induction of nuclear factor kappa B (NF-kappa B).
S4 424-572 Sentence denotes Electrophoretic mobility shift assays demonstrate that LPS induces a DNA binding activity indistinguishable from NF-kappa B in U937 and THP-1 cells.
S5 573-760 Sentence denotes LPS is also shown to dramatically increase HIV-1 production from a chronically infected monocyte/macrophage-like cloned cell line, U1, which produces very low levels of HIV-1 at baseline.
S6 761-945 Sentence denotes The stimulation of viral production from this cell line occurs only if these cells are treated with granulocyte/macrophage colony-stimulating factor (GM-CSF) before treatment with LPS.
S7 946-1073 Sentence denotes This stimulation of HIV-1 production is correlated with an increase in the level of HIV-1 RNA and and activation of NF-kappa B.
S8 1074-1141 Sentence denotes LPS is not able to induce HIV-1 production in a cloned T cell line.
S9 1142-1339 Sentence denotes The effect of LPS on HIV-1 replication occurs at picogram per milliliter concentrations and may be clinically significant in understanding the variability of the natural history of HIV-1 infection.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 0-18 NP denotes Lipopolysaccharide
C2 122-146 NP denotes Lipopolysaccharide (LPS)
C3 387-422 NP denotes nuclear factor kappa B (NF-kappa B)
C4 479-482 NP denotes LPS
C5 537-547 NP denotes NF-kappa B
C6 573-576 NP denotes LPS
C7 616-632 NP denotes HIV-1 production
C8 638-702 NP denotes a chronically infected monocyte/macrophage-like cloned cell line
C9 704-706 NP denotes U1
C10 708-713 NP denotes which
C11 761-796 NP denotes The stimulation of viral production
C12 802-816 NP denotes this cell line
C13 832-843 NP denotes these cells
C14 941-944 NP denotes LPS
C16 966-982 NP denotes HIV-1 production
C15 946-982 NP denotes This stimulation of HIV-1 production
C17 1062-1072 NP denotes NF-kappa B
C18 1074-1077 NP denotes LPS
C19 1100-1116 NP denotes HIV-1 production
C20 1156-1159 NP denotes LPS
R1 C2 C1 coref-ident Lipopolysaccharide (LPS),Lipopolysaccharide
R2 C4 C2 coref-ident LPS,Lipopolysaccharide (LPS)
R3 C5 C3 coref-ident NF-kappa B,nuclear factor kappa B (NF-kappa B)
R4 C6 C4 coref-ident LPS,LPS
R5 C9 C8 coref-appos U1,a chronically infected monocyte/macrophage-like cloned cell line
R6 C10 C9 coref-relat which,U1
R7 C12 C8 coref-ident this cell line,a chronically infected monocyte/macrophage-like cloned cell line
R8 C13 C12 coref-ident these cells,this cell line
R9 C14 C6 coref-ident LPS,LPS
R10 C16 C7 coref-ident HIV-1 production,HIV-1 production
R11 C15 C11 coref-ident This stimulation of HIV-1 production,The stimulation of viral production
R12 C17 C5 coref-ident NF-kappa B,NF-kappa B
R13 C18 C14 coref-ident LPS,LPS
R14 C19 C16 coref-ident HIV-1 production,HIV-1 production
R15 C20 C18 coref-ident LPS,LPS

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 0-18 lipid denotes Lipopolysaccharide
T2 31-70 other_name denotes monocyte/macrophage-specific stimulator
T3 74-102 virus denotes human immunodeficiency virus
T4 110-120 other_name denotes expression
T5 122-140 lipid denotes Lipopolysaccharide
T6 142-145 lipid denotes LPS
T7 167-195 virus denotes human immunodeficiency virus
T8 225-234 DNA_domain_or_region denotes HIV-1-LTR
T9 268-303 cell_line denotes monocyte/macrophage-like cell lines
T10 314-325 cell_line denotes T cell line
T11 387-409 protein_molecule denotes nuclear factor kappa B
T12 411-421 protein_molecule denotes NF-kappa B
T13 424-461 other_name denotes Electrophoretic mobility shift assays
T14 479-482 lipid denotes LPS
T15 493-513 other_name denotes DNA binding activity
T16 537-547 protein_molecule denotes NF-kappa B
T17 551-555 cell_line denotes U937
T18 560-571 cell_line denotes THP-1 cells
T19 573-576 lipid denotes LPS
T20 616-632 other_name denotes HIV-1 production
T21 640-702 cell_line denotes chronically infected monocyte/macrophage-like cloned cell line
T22 704-706 cell_line denotes U1
T23 742-747 virus denotes HIV-1
T24 780-796 other_name denotes viral production
T25 861-909 protein_molecule denotes granulocyte/macrophage colony-stimulating factor
T26 911-917 protein_molecule denotes GM-CSF
T27 941-944 lipid denotes LPS
T28 966-971 virus denotes HIV-1
T29 1030-1035 virus denotes HIV-1
T30 1062-1072 protein_molecule denotes NF-kappa B
T31 1074-1077 lipid denotes LPS
T32 1100-1105 virus denotes HIV-1
T33 1129-1140 cell_line denotes T cell line
T34 1156-1159 lipid denotes LPS
T35 1163-1168 virus denotes HIV-1
T36 1323-1328 virus denotes HIV-1