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PubMed:2123468 JSONTXT

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jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 23-43 protein denotes transcription factor
T2 121-144 protein denotes T-cell antigen receptor
T3 161-174 cell_type denotes T lymphocytes
T4 189-205 protein denotes antigen receptor
T5 241-262 protein denotes transcription factors
T6 274-279 protein denotes NF-AT
T7 284-294 protein denotes NF-kappa B
T8 412-432 protein denotes transcription factor
T9 436-459 cell_type denotes individual viable cells
T10 549-567 protein denotes beta-galactosidase
T11 569-577 protein denotes beta-gal
T12 617-622 protein denotes NF-AT
T13 654-661 cell_type denotes T cells
T14 741-759 DNA denotes NF-AT-binding site
T15 789-798 DNA denotes lacZ gene
T16 829-869 cell_line denotes cloned stably transfected Jurkat T cells
T17 951-959 protein denotes beta-gal
T18 1113-1121 protein denotes beta-gal
T19 1150-1155 protein denotes NF-AT
T20 1209-1214 protein denotes NF-AT
T21 1315-1320 protein denotes NF-AT
T22 1357-1380 protein denotes transcription complexes
T23 1388-1396 DNA denotes promoter
T24 1431-1441 protein denotes NF-kappa B
T25 1456-1478 DNA denotes interleukin-2 enhancer
T26 1585-1606 protein denotes transcription factors
T27 1635-1650 DNA denotes inducible genes

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-145 Sentence denotes Single cell assay of a transcription factor reveals a threshold in transcription activated by signals emanating from the T-cell antigen receptor.
S2 146-371 Sentence denotes Stimulation of T lymphocytes through their antigen receptor leads to the appearance of several transcription factors, including NF-AT and NF-kappa B, which are involved in regulating genes required for immunologic activation.
S3 372-579 Sentence denotes To investigate the activity of a single transcription factor in individual viable cells, we have applied an assay that uses the fluorescence-activated cell sorter to quantitate beta-galactosidase (beta-gal).
S4 580-799 Sentence denotes We have analyzed the distribution of NF-AT transcriptional activity among T cells undergoing activation by using a construct in which three tandem copies of the NF-AT-binding site directs transcription of the lacZ gene.
S5 800-991 Sentence denotes Unexpectedly, stimulation of cloned stably transfected Jurkat T cells leads to a bimodal pattern of beta-gal expression in which some cells express no beta-gal and others express high levels.
S6 992-1086 Sentence denotes This expression pattern cannot be accounted for by cell-cycle position or heritable variation.
S7 1087-1279 Sentence denotes Further results, in which beta-gal activity is correlated with NF-AT-binding activity, indicate that the concentration of NF-AT must exceed a critical threshold before transcription initiates.
S8 1280-1397 Sentence denotes This threshold likely reflects the NF-AT concentration-dependent assembly of transcription complexes at the promoter.
S9 1398-1651 Sentence denotes Similar constructs controlled by NF-kappa B or the entire interleukin-2 enhancer show bimodal expression patterns during induction, suggesting that thresholds set by the concentration of transcription factors may be a common property of inducible genes.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 117-144 NP denotes the T-cell antigen receptor
C2 161-174 NP denotes T lymphocytes
C4 183-188 NP denotes their
C3 183-205 NP denotes their antigen receptor
C5 233-262 NP denotes several transcription factors
C6 284-294 NP denotes NF-kappa B
C7 296-301 NP denotes which
C8 477-485 NP denotes an assay
C9 486-490 NP denotes that
C10 549-578 NP denotes beta-galactosidase (beta-gal)
C11 693-704 NP denotes a construct
C12 708-713 NP denotes which
C14 879-919 NP denotes a bimodal pattern of beta-gal expression
C15 923-928 NP denotes which
C16 951-959 NP denotes beta-gal
C13 879-990 NP denotes a bimodal pattern of beta-gal expression in which some cells express no beta-gal and others express high levels
C17 992-1015 NP denotes This expression pattern
C18 1227-1247 NP denotes a critical threshold
C19 1280-1294 NP denotes This threshold
C20 1431-1441 NP denotes NF-kappa B
R1 C4 C2 coref-pron their,T lymphocytes
R2 C3 C1 coref-ident their antigen receptor,the T-cell antigen receptor
R3 C7 C5 coref-relat which,several transcription factors
R4 C9 C8 coref-relat that,an assay
R5 C12 C11 coref-relat which,a construct
R6 C15 C13 coref-relat which,a bimodal pattern of beta-gal expression in which some cells express no beta-gal and others express high levels
R7 C16 C10 coref-ident beta-gal,beta-galactosidase (beta-gal)
R8 C17 C14 coref-ident This expression pattern,a bimodal pattern of beta-gal expression
R9 C19 C18 coref-ident This threshold,a critical threshold
R10 C20 C6 coref-ident NF-kappa B,NF-kappa B

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 23-43 protein_family_or_group denotes transcription factor
T2 67-80 other_name denotes transcription
T3 121-144 protein_family_or_group denotes T-cell antigen receptor
T4 161-174 cell_type denotes T lymphocytes
T5 189-205 protein_family_or_group denotes antigen receptor
T6 241-262 protein_family_or_group denotes transcription factors
T7 274-279 protein_molecule denotes NF-AT
T8 284-294 protein_molecule denotes NF-kappa B
T9 412-432 protein_family_or_group denotes transcription factor
T10 436-459 cell_type denotes individual viable cells
T11 549-567 protein_molecule denotes beta-galactosidase
T12 569-577 protein_molecule denotes beta-gal
T13 617-622 protein_molecule denotes NF-AT
T14 654-661 cell_type denotes T cells
T15 741-746 protein_molecule denotes NF-AT
T16 768-781 other_name denotes transcription
T17 789-798 DNA_domain_or_region denotes lacZ gene
T18 829-861 cell_line denotes cloned stably transfected Jurkat
T19 862-869 cell_type denotes T cells
T20 951-959 protein_molecule denotes beta-gal
T21 1113-1121 protein_molecule denotes beta-gal
T22 1150-1155 protein_molecule denotes NF-AT
T23 1209-1214 protein_molecule denotes NF-AT
T24 1255-1268 other_name denotes transcription
T25 1315-1320 protein_molecule denotes NF-AT
T26 1357-1380 protein_complex denotes transcription complexes
T27 1388-1396 DNA_domain_or_region denotes promoter
T28 1431-1441 protein_molecule denotes NF-kappa B
T29 1456-1478 DNA_domain_or_region denotes interleukin-2 enhancer
T30 1484-1511 other_name denotes bimodal expression patterns
T31 1585-1606 protein_family_or_group denotes transcription factors
T32 1635-1650 DNA_family_or_group denotes inducible genes