PubMed:21209915 / 0-327 JSONTXT

{"project":"sentences","denotations":[{"id":"TextSentencer_T1","span":{"begin":0,"end":124},"obj":"Sentence"},{"id":"TextSentencer_T2","span":{"begin":125,"end":136},"obj":"Sentence"},{"id":"TextSentencer_T3","span":{"begin":137,"end":299},"obj":"Sentence"},{"id":"T1","span":{"begin":0,"end":124},"obj":"Sentence"},{"id":"T2","span":{"begin":125,"end":136},"obj":"Sentence"},{"id":"T3","span":{"begin":137,"end":299},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Inactivation of the FLCN tumor suppressor gene induces TFE3 transcriptional activity by increasing its nuclear localization.\nBACKGROUND: Germline mutations in a tumor suppressor gene FLCN lead to development of fibrofolliculomas, lung cysts and renal cell carcinoma (RCC) in Birt-Hogg-Dubé syndrome. TFE3 is a member of the MiT"}

{"project":"PubmedHPO","denotations":[{"id":"T1","span":{"begin":161,"end":166},"obj":"HP_0002664"},{"id":"T2","span":{"begin":211,"end":228},"obj":"HP_0030436"},{"id":"T3","span":{"begin":245,"end":265},"obj":"HP_0005584"}],"text":"Inactivation of the FLCN tumor suppressor gene induces TFE3 transcriptional activity by increasing its nuclear localization.\nBACKGROUND: Germline mutations in a tumor suppressor gene FLCN lead to development of fibrofolliculomas, lung cysts and renal cell carcinoma (RCC) in Birt-Hogg-Dubé syndrome. TFE3 is a member of the MiT"}

{"project":"Allie","denotations":[{"id":"SS1_21209915_2_0","span":{"begin":245,"end":265},"obj":"expanded"},{"id":"SS2_21209915_2_0","span":{"begin":267,"end":270},"obj":"abbr"}],"relations":[{"id":"AE1_21209915_2_0","pred":"abbreviatedTo","subj":"SS1_21209915_2_0","obj":"SS2_21209915_2_0"}],"text":"Inactivation of the FLCN tumor suppressor gene induces TFE3 transcriptional activity by increasing its nuclear localization.\nBACKGROUND: Germline mutations in a tumor suppressor gene FLCN lead to development of fibrofolliculomas, lung cysts and renal cell carcinoma (RCC) in Birt-Hogg-Dubé syndrome. TFE3 is a member of the MiT"}

{"project":"DisGeNET5_gene_disease","denotations":[{"id":"21209915-1#46#50#gene201163","span":{"begin":183,"end":187},"obj":"gene201163"},{"id":"21209915-1#74#91#diseaseC0346011","span":{"begin":211,"end":228},"obj":"diseaseC0346011"},{"id":"21209915-1#108#128#diseaseC0007134","span":{"begin":245,"end":265},"obj":"diseaseC0007134"},{"id":"21209915-1#130#133#diseaseC0007134","span":{"begin":267,"end":270},"obj":"diseaseC0007134"},{"id":"21209915-1#138#161#diseaseC0346010","span":{"begin":275,"end":298},"obj":"diseaseC0346010"}],"relations":[{"id":"46#50#gene20116374#91#diseaseC0346011","pred":"associated_with","subj":"21209915-1#46#50#gene201163","obj":"21209915-1#74#91#diseaseC0346011"},{"id":"46#50#gene201163108#128#diseaseC0007134","pred":"associated_with","subj":"21209915-1#46#50#gene201163","obj":"21209915-1#108#128#diseaseC0007134"},{"id":"46#50#gene201163130#133#diseaseC0007134","pred":"associated_with","subj":"21209915-1#46#50#gene201163","obj":"21209915-1#130#133#diseaseC0007134"},{"id":"46#50#gene201163138#161#diseaseC0346010","pred":"associated_with","subj":"21209915-1#46#50#gene201163","obj":"21209915-1#138#161#diseaseC0346010"}],"text":"Inactivation of the FLCN tumor suppressor gene induces TFE3 transcriptional activity by increasing its nuclear localization.\nBACKGROUND: Germline mutations in a tumor suppressor gene FLCN lead to development of fibrofolliculomas, lung cysts and renal cell carcinoma (RCC) in Birt-Hogg-Dubé syndrome. TFE3 is a member of the MiT"}

{"project":"UBERON-AE","denotations":[{"id":"PD-UBERON-AE-B_T1","span":{"begin":230,"end":234},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"}],"text":"Inactivation of the FLCN tumor suppressor gene induces TFE3 transcriptional activity by increasing its nuclear localization.\nBACKGROUND: Germline mutations in a tumor suppressor gene FLCN lead to development of fibrofolliculomas, lung cysts and renal cell carcinoma (RCC) in Birt-Hogg-Dubé syndrome. TFE3 is a member of the MiT"}

{"project":"performance-test","denotations":[{"id":"PD-UBERON-AE-B_T1","span":{"begin":230,"end":234},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"}],"text":"Inactivation of the FLCN tumor suppressor gene induces TFE3 transcriptional activity by increasing its nuclear localization.\nBACKGROUND: Germline mutations in a tumor suppressor gene FLCN lead to development of fibrofolliculomas, lung cysts and renal cell carcinoma (RCC) in Birt-Hogg-Dubé syndrome. TFE3 is a member of the MiT"}