PubMed:20520283 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/20520283","sourcedb":"PubMed","sourceid":"20520283","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/20520283","text":"Efficacy and safety of asenapine in a placebo- and haloperidol-controlled trial in patients with acute exacerbation of schizophrenia.\nAsenapine is approved by the Food and Drugs Administration in adults for acute treatment of schizophrenia or of manic or mixed episodes associated with bipolar I disorder with or without psychotic features. In a double-blind 6-week trial, 458 patients with acute schizophrenia were randomly assigned to fixed-dose treatment with asenapine at 5 mg twice daily (BID), asenapine at 10 mg BID, placebo, or haloperidol at 4 mg BID (to verify assay sensitivity). With last observations carried forward (LOCF), mean Positive and Negative Syndrome Scale total score reductions from baseline to endpoint were significantly greater with asenapine at 5 mg BID (-16.2) and haloperidol (-15.4) than placebo (-10.7; both P \u003c 0.05); using mixed model for repeated measures (MMRM), changes at day 42 were significantly greater with asenapine at 5 and 10 mg BID (-21.3 and -19.4, respectively) and haloperidol (-20.0) than placebo (-14.6; all P \u003c 0.05). On the Positive and Negative Syndrome Scale positive subscale, all treatments were superior to placebo with LOCF and MMRM; asenapine at 5 mg BID was superior to placebo on the negative subscale with MMRM and on the general psychopathology subscale with LOCF and MMRM. Treatment-related adverse events (AEs) occurred in 44% and 52%, 57%, and 41% of the asenapine at 5 and 10 mg BID, haloperidol, and placebo groups, respectively. Extrapyramidal symptoms reported as AEs occurred in 15% and 18%, 34%, and 10% of the asenapine at 5 and 10 mg BID, haloperidol, and placebo groups, respectively. Across all groups, no more than 5% of patients had clinically significant weight change. Post hoc analyses indicated that efficacy was similar with asenapine and haloperidol; greater contrasts were seen in AEs, especially extrapyramidal symptoms.","tracks":[{"project":"TEST-DiseaseOrPhenotypicFeature","denotations":[{"id":"T1","span":{"begin":119,"end":132},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":226,"end":239},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":286,"end":304},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":397,"end":410},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T5","span":{"begin":1500,"end":1523},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T6","span":{"begin":1884,"end":1907},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A1","pred":"#label","subj":"T1","obj":"D012559"},{"id":"A2","pred":"#label","subj":"T2","obj":"D012559"},{"id":"A3","pred":"#label","subj":"T3","obj":"DISEASE"},{"id":"A4","pred":"#label","subj":"T4","obj":"D012559"},{"id":"A5","pred":"#label","subj":"T5","obj":"DISEASE"},{"id":"A6","pred":"#label","subj":"T6","obj":"DISEASE"},{"subj":"T1","pred":"source","obj":"TEST-DiseaseOrPhenotypicFeature"},{"subj":"T2","pred":"source","obj":"TEST-DiseaseOrPhenotypicFeature"},{"subj":"T3","pred":"source","obj":"TEST-DiseaseOrPhenotypicFeature"},{"subj":"T4","pred":"source","obj":"TEST-DiseaseOrPhenotypicFeature"},{"subj":"T5","pred":"source","obj":"TEST-DiseaseOrPhenotypicFeature"},{"subj":"T6","pred":"source","obj":"TEST-DiseaseOrPhenotypicFeature"}]},{"project":"TEST-ChemicalEntity","denotations":[{"id":"T1","span":{"begin":23,"end":32},"obj":"ChemicalEntity"},{"id":"T3","span":{"begin":51,"end":62},"obj":"ChemicalEntity"},{"id":"T5","span":{"begin":134,"end":143},"obj":"ChemicalEntity"},{"id":"T7","span":{"begin":463,"end":472},"obj":"ChemicalEntity"},{"id":"T9","span":{"begin":500,"end":509},"obj":"ChemicalEntity"},{"id":"T11","span":{"begin":536,"end":547},"obj":"ChemicalEntity"},{"id":"T13","span":{"begin":761,"end":770},"obj":"ChemicalEntity"},{"id":"T15","span":{"begin":795,"end":806},"obj":"ChemicalEntity"},{"id":"T17","span":{"begin":950,"end":959},"obj":"ChemicalEntity"},{"id":"T19","span":{"begin":1015,"end":1026},"obj":"ChemicalEntity"},{"id":"T21","span":{"begin":1194,"end":1203},"obj":"ChemicalEntity"},{"id":"T23","span":{"begin":1423,"end":1432},"obj":"ChemicalEntity"},{"id":"T25","span":{"begin":1453,"end":1464},"obj":"ChemicalEntity"},{"id":"T27","span":{"begin":1585,"end":1594},"obj":"ChemicalEntity"},{"id":"T29","span":{"begin":1615,"end":1626},"obj":"ChemicalEntity"},{"id":"T31","span":{"begin":1810,"end":1819},"obj":"ChemicalEntity"},{"id":"T33","span":{"begin":1824,"end":1835},"obj":"ChemicalEntity"}],"attributes":[{"id":"A3","pred":"ID:","subj":"T3","obj":"D006220"},{"id":"A4","pred":"ID:","subj":"T3","obj":"http://purl.obolibrary.org/obo/CHEBI_5613"},{"id":"A27","pred":"ID:","subj":"T27","obj":"C522667"},{"id":"A28","pred":"ID:","subj":"T27","obj":"http://purl.obolibrary.org/obo/CHEBI_71253"},{"id":"A13","pred":"ID:","subj":"T13","obj":"C522667"},{"id":"A14","pred":"ID:","subj":"T13","obj":"http://purl.obolibrary.org/obo/CHEBI_71253"},{"id":"A25","pred":"ID:","subj":"T25","obj":"D006220"},{"id":"A26","pred":"ID:","subj":"T25","obj":"http://purl.obolibrary.org/obo/CHEBI_5613"},{"id":"A21","pred":"ID:","subj":"T21","obj":"C522667"},{"id":"A22","pred":"ID:","subj":"T21","obj":"http://purl.obolibrary.org/obo/CHEBI_71253"},{"id":"A33","pred":"ID:","subj":"T33","obj":"D006220"},{"id":"A34","pred":"ID:","subj":"T33","obj":"http://purl.obolibrary.org/obo/CHEBI_5613"},{"id":"A17","pred":"ID:","subj":"T17","obj":"C522667"},{"id":"A18","pred":"ID:","subj":"T17","obj":"http://purl.obolibrary.org/obo/CHEBI_71253"},{"id":"A7","pred":"ID:","subj":"T7","obj":"C522667"},{"id":"A8","pred":"ID:","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_71253"},{"id":"A1","pred":"ID:","subj":"T1","obj":"C522667"},{"id":"A2","pred":"ID:","subj":"T1","obj":"http://purl.obolibrary.org/obo/CHEBI_71253"},{"id":"A9","pred":"ID:","subj":"T9","obj":"C522667"},{"id":"A10","pred":"ID:","subj":"T9","obj":"http://purl.obolibrary.org/obo/CHEBI_71253"},{"id":"A31","pred":"ID:","subj":"T31","obj":"C522667"},{"id":"A32","pred":"ID:","subj":"T31","obj":"http://purl.obolibrary.org/obo/CHEBI_71253"},{"id":"A19","pred":"ID:","subj":"T19","obj":"D006220"},{"id":"A20","pred":"ID:","subj":"T19","obj":"http://purl.obolibrary.org/obo/CHEBI_5613"},{"id":"A11","pred":"ID:","subj":"T11","obj":"D006220"},{"id":"A12","pred":"ID:","subj":"T11","obj":"http://purl.obolibrary.org/obo/CHEBI_5613"},{"id":"A23","pred":"ID:","subj":"T23","obj":"C522667"},{"id":"A24","pred":"ID:","subj":"T23","obj":"http://purl.obolibrary.org/obo/CHEBI_71253"},{"id":"A5","pred":"ID:","subj":"T5","obj":"C522667"},{"id":"A6","pred":"ID:","subj":"T5","obj":"http://purl.obolibrary.org/obo/CHEBI_71253"},{"id":"A29","pred":"ID:","subj":"T29","obj":"D006220"},{"id":"A30","pred":"ID:","subj":"T29","obj":"http://purl.obolibrary.org/obo/CHEBI_5613"},{"id":"A15","pred":"ID:","subj":"T15","obj":"D006220"},{"id":"A16","pred":"ID:","subj":"T15","obj":"http://purl.obolibrary.org/obo/CHEBI_5613"},{"subj":"T1","pred":"source","obj":"TEST-ChemicalEntity"},{"subj":"T3","pred":"source","obj":"TEST-ChemicalEntity"},{"subj":"T5","pred":"source","obj":"TEST-ChemicalEntity"},{"subj":"T7","pred":"source","obj":"TEST-ChemicalEntity"},{"subj":"T9","pred":"source","obj":"TEST-ChemicalEntity"},{"subj":"T11","pred":"source","obj":"TEST-ChemicalEntity"},{"subj":"T13","pred":"source","obj":"TEST-ChemicalEntity"},{"subj":"T15","pred":"source","obj":"TEST-ChemicalEntity"},{"subj":"T17","pred":"source","obj":"TEST-ChemicalEntity"},{"subj":"T19","pred":"source","obj":"TEST-ChemicalEntity"},{"subj":"T21","pred":"source","obj":"TEST-ChemicalEntity"},{"subj":"T23","pred":"source","obj":"TEST-ChemicalEntity"},{"subj":"T25","pred":"source","obj":"TEST-ChemicalEntity"},{"subj":"T27","pred":"source","obj":"TEST-ChemicalEntity"},{"subj":"T29","pred":"source","obj":"TEST-ChemicalEntity"},{"subj":"T31","pred":"source","obj":"TEST-ChemicalEntity"},{"subj":"T33","pred":"source","obj":"TEST-ChemicalEntity"}]},{"project":"TEST-OrganismTaxon","denotations":[{"id":"T1","span":{"begin":83,"end":91},"obj":"OrganismTaxon"},{"id":"T2","span":{"begin":286,"end":295},"obj":"OrganismTaxon"},{"id":"T3","span":{"begin":377,"end":385},"obj":"OrganismTaxon"},{"id":"T4","span":{"begin":1700,"end":1708},"obj":"OrganismTaxon"}],"attributes":[{"subj":"T1","pred":"source","obj":"TEST-OrganismTaxon"},{"subj":"T2","pred":"source","obj":"TEST-OrganismTaxon"},{"subj":"T3","pred":"source","obj":"TEST-OrganismTaxon"},{"subj":"T4","pred":"source","obj":"TEST-OrganismTaxon"}]},{"project":"Test-merged","denotations":[{"id":"T6","span":{"begin":1884,"end":1907},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T5","span":{"begin":1500,"end":1523},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":397,"end":410},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":286,"end":304},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":226,"end":239},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T1","span":{"begin":119,"end":132},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T9704","span":{"begin":1700,"end":1708},"obj":"OrganismTaxon"},{"id":"T40754","span":{"begin":377,"end":385},"obj":"OrganismTaxon"},{"id":"T99368","span":{"begin":83,"end":91},"obj":"OrganismTaxon"},{"id":"T29189","span":{"begin":1056,"end":1061},"obj":"GeneOrGeneProduct"},{"id":"T33","span":{"begin":1824,"end":1835},"obj":"ChemicalEntity"},{"id":"T31","span":{"begin":1810,"end":1819},"obj":"ChemicalEntity"},{"id":"T29","span":{"begin":1615,"end":1626},"obj":"ChemicalEntity"},{"id":"T27","span":{"begin":1585,"end":1594},"obj":"ChemicalEntity"},{"id":"T25","span":{"begin":1453,"end":1464},"obj":"ChemicalEntity"},{"id":"T23","span":{"begin":1423,"end":1432},"obj":"ChemicalEntity"},{"id":"T21","span":{"begin":1194,"end":1203},"obj":"ChemicalEntity"},{"id":"T19","span":{"begin":1015,"end":1026},"obj":"ChemicalEntity"},{"id":"T17","span":{"begin":950,"end":959},"obj":"ChemicalEntity"},{"id":"T15","span":{"begin":795,"end":806},"obj":"ChemicalEntity"},{"id":"T13","span":{"begin":761,"end":770},"obj":"ChemicalEntity"},{"id":"T11","span":{"begin":536,"end":547},"obj":"ChemicalEntity"},{"id":"T9","span":{"begin":500,"end":509},"obj":"ChemicalEntity"},{"id":"T7","span":{"begin":463,"end":472},"obj":"ChemicalEntity"},{"id":"T3195","span":{"begin":134,"end":143},"obj":"ChemicalEntity"},{"id":"T27170","span":{"begin":51,"end":62},"obj":"ChemicalEntity"},{"id":"T96910","span":{"begin":23,"end":32},"obj":"ChemicalEntity"}],"attributes":[{"id":"A22","pred":"ID:","subj":"T21","obj":"http://purl.obolibrary.org/obo/CHEBI_71253"},{"id":"A21","pred":"ID:","subj":"T21","obj":"C522667"},{"id":"A2","pred":"#label","subj":"T2","obj":"D012559"},{"id":"A24","pred":"ID:","subj":"T23","obj":"http://purl.obolibrary.org/obo/CHEBI_71253"},{"id":"A23","pred":"ID:","subj":"T23","obj":"C522667"},{"id":"A6","pred":"#label","subj":"T6","obj":"DISEASE"},{"id":"A20","pred":"ID:","subj":"T19","obj":"http://purl.obolibrary.org/obo/CHEBI_5613"},{"id":"A19","pred":"ID:","subj":"T19","obj":"D006220"},{"id":"A3","pred":"#label","subj":"T3","obj":"DISEASE"},{"id":"A4","pred":"#label","subj":"T4","obj":"D012559"},{"id":"A18","pred":"ID:","subj":"T17","obj":"http://purl.obolibrary.org/obo/CHEBI_71253"},{"id":"A17","pred":"ID:","subj":"T17","obj":"C522667"},{"id":"A5","pred":"#label","subj":"T5","obj":"DISEASE"},{"id":"A32","pred":"ID:","subj":"T31","obj":"http://purl.obolibrary.org/obo/CHEBI_71253"},{"id":"A31","pred":"ID:","subj":"T31","obj":"C522667"},{"id":"A12","pred":"ID:","subj":"T11","obj":"http://purl.obolibrary.org/obo/CHEBI_5613"},{"id":"A11","pred":"ID:","subj":"T11","obj":"D006220"},{"id":"A14","pred":"ID:","subj":"T13","obj":"http://purl.obolibrary.org/obo/CHEBI_71253"},{"id":"A13","pred":"ID:","subj":"T13","obj":"C522667"},{"id":"A1","pred":"#label","subj":"T1","obj":"D012559"},{"id":"A32154","pred":"ID:","subj":"T3195","obj":"http://purl.obolibrary.org/obo/CHEBI_71253"},{"id":"A521","pred":"ID:","subj":"T3195","obj":"C522667"},{"id":"A10","pred":"ID:","subj":"T9","obj":"http://purl.obolibrary.org/obo/CHEBI_71253"},{"id":"A9","pred":"ID:","subj":"T9","obj":"C522667"},{"id":"A26","pred":"ID:","subj":"T25","obj":"http://purl.obolibrary.org/obo/CHEBI_5613"},{"id":"A25","pred":"ID:","subj":"T25","obj":"D006220"},{"id":"A8","pred":"ID:","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_71253"},{"id":"A7","pred":"ID:","subj":"T7","obj":"C522667"},{"id":"A86044","pred":"ID:","subj":"T27170","obj":"http://purl.obolibrary.org/obo/CHEBI_5613"},{"id":"A68993","pred":"ID:","subj":"T27170","obj":"D006220"},{"id":"A34","pred":"ID:","subj":"T33","obj":"http://purl.obolibrary.org/obo/CHEBI_5613"},{"id":"A33","pred":"ID:","subj":"T33","obj":"D006220"},{"id":"A6479","pred":"ID:","subj":"T96910","obj":"http://purl.obolibrary.org/obo/CHEBI_71253"},{"id":"A64972","pred":"ID:","subj":"T96910","obj":"C522667"},{"id":"A30","pred":"ID:","subj":"T29","obj":"http://purl.obolibrary.org/obo/CHEBI_5613"},{"id":"A29","pred":"ID:","subj":"T29","obj":"D006220"},{"id":"A28","pred":"ID:","subj":"T27","obj":"http://purl.obolibrary.org/obo/CHEBI_71253"},{"id":"A27","pred":"ID:","subj":"T27","obj":"C522667"},{"id":"A16","pred":"ID:","subj":"T15","obj":"http://purl.obolibrary.org/obo/CHEBI_5613"},{"id":"A15","pred":"ID:","subj":"T15","obj":"D006220"},{"subj":"T6","pred":"source","obj":"Test-merged"},{"subj":"T5","pred":"source","obj":"Test-merged"},{"subj":"T4","pred":"source","obj":"Test-merged"},{"subj":"T3","pred":"source","obj":"Test-merged"},{"subj":"T2","pred":"source","obj":"Test-merged"},{"subj":"T1","pred":"source","obj":"Test-merged"},{"subj":"T9704","pred":"source","obj":"Test-merged"},{"subj":"T40754","pred":"source","obj":"Test-merged"},{"subj":"T99368","pred":"source","obj":"Test-merged"},{"subj":"T29189","pred":"source","obj":"Test-merged"},{"subj":"T33","pred":"source","obj":"Test-merged"},{"subj":"T31","pred":"source","obj":"Test-merged"},{"subj":"T29","pred":"source","obj":"Test-merged"},{"subj":"T27","pred":"source","obj":"Test-merged"},{"subj":"T25","pred":"source","obj":"Test-merged"},{"subj":"T23","pred":"source","obj":"Test-merged"},{"subj":"T21","pred":"source","obj":"Test-merged"},{"subj":"T19","pred":"source","obj":"Test-merged"},{"subj":"T17","pred":"source","obj":"Test-merged"},{"subj":"T15","pred":"source","obj":"Test-merged"},{"subj":"T13","pred":"source","obj":"Test-merged"},{"subj":"T11","pred":"source","obj":"Test-merged"},{"subj":"T9","pred":"source","obj":"Test-merged"},{"subj":"T7","pred":"source","obj":"Test-merged"},{"subj":"T3195","pred":"source","obj":"Test-merged"},{"subj":"T27170","pred":"source","obj":"Test-merged"},{"subj":"T96910","pred":"source","obj":"Test-merged"}]},{"project":"Test-GeneOrGeneProduct","denotations":[{"id":"T1","span":{"begin":1056,"end":1061},"obj":"GeneOrGeneProduct"}],"attributes":[{"subj":"T1","pred":"source","obj":"Test-GeneOrGeneProduct"}]},{"project":"Test-merged-2","denotations":[{"id":"T96910","span":{"begin":23,"end":32},"obj":"ChemicalEntity"},{"id":"T27170","span":{"begin":51,"end":62},"obj":"ChemicalEntity"},{"id":"T3195","span":{"begin":134,"end":143},"obj":"ChemicalEntity"},{"id":"T7","span":{"begin":463,"end":472},"obj":"ChemicalEntity"},{"id":"T9","span":{"begin":500,"end":509},"obj":"ChemicalEntity"},{"id":"T11","span":{"begin":536,"end":547},"obj":"ChemicalEntity"},{"id":"T13","span":{"begin":761,"end":770},"obj":"ChemicalEntity"},{"id":"T15","span":{"begin":795,"end":806},"obj":"ChemicalEntity"},{"id":"T17","span":{"begin":950,"end":959},"obj":"ChemicalEntity"},{"id":"T19","span":{"begin":1015,"end":1026},"obj":"ChemicalEntity"},{"id":"T21","span":{"begin":1194,"end":1203},"obj":"ChemicalEntity"},{"id":"T23","span":{"begin":1423,"end":1432},"obj":"ChemicalEntity"},{"id":"T25","span":{"begin":1453,"end":1464},"obj":"ChemicalEntity"},{"id":"T27","span":{"begin":1585,"end":1594},"obj":"ChemicalEntity"},{"id":"T29","span":{"begin":1615,"end":1626},"obj":"ChemicalEntity"},{"id":"T31","span":{"begin":1810,"end":1819},"obj":"ChemicalEntity"},{"id":"T33","span":{"begin":1824,"end":1835},"obj":"ChemicalEntity"},{"id":"T29189","span":{"begin":1056,"end":1061},"obj":"GeneOrGeneProduct"},{"id":"T99368","span":{"begin":83,"end":91},"obj":"OrganismTaxon"},{"id":"T82371","span":{"begin":286,"end":295},"obj":"OrganismTaxon"},{"id":"T40754","span":{"begin":377,"end":385},"obj":"OrganismTaxon"},{"id":"T9704","span":{"begin":1700,"end":1708},"obj":"OrganismTaxon"},{"id":"T1","span":{"begin":119,"end":132},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":226,"end":239},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":286,"end":304},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":397,"end":410},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T5","span":{"begin":1500,"end":1523},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T6","span":{"begin":1884,"end":1907},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A29","pred":"ID:","subj":"T29","obj":"D006220"},{"id":"A30","pred":"ID:","subj":"T29","obj":"http://purl.obolibrary.org/obo/CHEBI_5613"},{"id":"A11","pred":"ID:","subj":"T11","obj":"D006220"},{"id":"A12","pred":"ID:","subj":"T11","obj":"http://purl.obolibrary.org/obo/CHEBI_5613"},{"id":"A23","pred":"ID:","subj":"T23","obj":"C522667"},{"id":"A24","pred":"ID:","subj":"T23","obj":"http://purl.obolibrary.org/obo/CHEBI_71253"},{"id":"A13","pred":"ID:","subj":"T13","obj":"C522667"},{"id":"A14","pred":"ID:","subj":"T13","obj":"http://purl.obolibrary.org/obo/CHEBI_71253"},{"id":"A19","pred":"ID:","subj":"T19","obj":"D006220"},{"id":"A20","pred":"ID:","subj":"T19","obj":"http://purl.obolibrary.org/obo/CHEBI_5613"},{"id":"A31","pred":"ID:","subj":"T31","obj":"C522667"},{"id":"A32","pred":"ID:","subj":"T31","obj":"http://purl.obolibrary.org/obo/CHEBI_71253"},{"id":"A64972","pred":"ID:","subj":"T96910","obj":"C522667"},{"id":"A6479","pred":"ID:","subj":"T96910","obj":"http://purl.obolibrary.org/obo/CHEBI_71253"},{"id":"A21","pred":"ID:","subj":"T21","obj":"C522667"},{"id":"A22","pred":"ID:","subj":"T21","obj":"http://purl.obolibrary.org/obo/CHEBI_71253"},{"id":"A15","pred":"ID:","subj":"T15","obj":"D006220"},{"id":"A16","pred":"ID:","subj":"T15","obj":"http://purl.obolibrary.org/obo/CHEBI_5613"},{"id":"A33","pred":"ID:","subj":"T33","obj":"D006220"},{"id":"A34","pred":"ID:","subj":"T33","obj":"http://purl.obolibrary.org/obo/CHEBI_5613"},{"id":"A4","pred":"#label","subj":"T4","obj":"D012559"},{"id":"A6","pred":"#label","subj":"T6","obj":"DISEASE"},{"id":"A1","pred":"#label","subj":"T1","obj":"D012559"},{"id":"A25","pred":"ID:","subj":"T25","obj":"D006220"},{"id":"A26","pred":"ID:","subj":"T25","obj":"http://purl.obolibrary.org/obo/CHEBI_5613"},{"id":"A27","pred":"ID:","subj":"T27","obj":"C522667"},{"id":"A28","pred":"ID:","subj":"T27","obj":"http://purl.obolibrary.org/obo/CHEBI_71253"},{"id":"A2","pred":"#label","subj":"T2","obj":"D012559"},{"id":"A521","pred":"ID:","subj":"T3195","obj":"C522667"},{"id":"A32154","pred":"ID:","subj":"T3195","obj":"http://purl.obolibrary.org/obo/CHEBI_71253"},{"id":"A3","pred":"#label","subj":"T3","obj":"DISEASE"},{"id":"A68993","pred":"ID:","subj":"T27170","obj":"D006220"},{"id":"A86044","pred":"ID:","subj":"T27170","obj":"http://purl.obolibrary.org/obo/CHEBI_5613"},{"id":"A9","pred":"ID:","subj":"T9","obj":"C522667"},{"id":"A10","pred":"ID:","subj":"T9","obj":"http://purl.obolibrary.org/obo/CHEBI_71253"},{"id":"A17","pred":"ID:","subj":"T17","obj":"C522667"},{"id":"A18","pred":"ID:","subj":"T17","obj":"http://purl.obolibrary.org/obo/CHEBI_71253"},{"id":"A5","pred":"#label","subj":"T5","obj":"DISEASE"},{"id":"A7","pred":"ID:","subj":"T7","obj":"C522667"},{"id":"A8","pred":"ID:","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_71253"},{"subj":"T96910","pred":"source","obj":"Test-merged-2"},{"subj":"T27170","pred":"source","obj":"Test-merged-2"},{"subj":"T3195","pred":"source","obj":"Test-merged-2"},{"subj":"T7","pred":"source","obj":"Test-merged-2"},{"subj":"T9","pred":"source","obj":"Test-merged-2"},{"subj":"T11","pred":"source","obj":"Test-merged-2"},{"subj":"T13","pred":"source","obj":"Test-merged-2"},{"subj":"T15","pred":"source","obj":"Test-merged-2"},{"subj":"T17","pred":"source","obj":"Test-merged-2"},{"subj":"T19","pred":"source","obj":"Test-merged-2"},{"subj":"T21","pred":"source","obj":"Test-merged-2"},{"subj":"T23","pred":"source","obj":"Test-merged-2"},{"subj":"T25","pred":"source","obj":"Test-merged-2"},{"subj":"T27","pred":"source","obj":"Test-merged-2"},{"subj":"T29","pred":"source","obj":"Test-merged-2"},{"subj":"T31","pred":"source","obj":"Test-merged-2"},{"subj":"T33","pred":"source","obj":"Test-merged-2"},{"subj":"T29189","pred":"source","obj":"Test-merged-2"},{"subj":"T99368","pred":"source","obj":"Test-merged-2"},{"subj":"T82371","pred":"source","obj":"Test-merged-2"},{"subj":"T40754","pred":"source","obj":"Test-merged-2"},{"subj":"T9704","pred":"source","obj":"Test-merged-2"},{"subj":"T1","pred":"source","obj":"Test-merged-2"},{"subj":"T2","pred":"source","obj":"Test-merged-2"},{"subj":"T3","pred":"source","obj":"Test-merged-2"},{"subj":"T4","pred":"source","obj":"Test-merged-2"},{"subj":"T5","pred":"source","obj":"Test-merged-2"},{"subj":"T6","pred":"source","obj":"Test-merged-2"}]},{"project":"PubmedHPO","denotations":[{"id":"T1","span":{"begin":226,"end":239},"obj":"HP_0100753"},{"id":"T2","span":{"begin":246,"end":251},"obj":"HP_0100754"},{"id":"T3","span":{"begin":286,"end":304},"obj":"HP_0007302"},{"id":"T4","span":{"begin":353,"end":358},"obj":"HP_0000618"},{"id":"T5","span":{"begin":397,"end":410},"obj":"HP_0100753"},{"id":"T6","span":{"begin":1500,"end":1523},"obj":"HP_0002071"},{"id":"T7","span":{"begin":1884,"end":1907},"obj":"HP_0002071"}],"attributes":[{"subj":"T1","pred":"source","obj":"PubmedHPO"},{"subj":"T2","pred":"source","obj":"PubmedHPO"},{"subj":"T3","pred":"source","obj":"PubmedHPO"},{"subj":"T4","pred":"source","obj":"PubmedHPO"},{"subj":"T5","pred":"source","obj":"PubmedHPO"},{"subj":"T6","pred":"source","obj":"PubmedHPO"},{"subj":"T7","pred":"source","obj":"PubmedHPO"}]},{"project":"Allie","denotations":[{"id":"SS1_20520283_3_0","span":{"begin":596,"end":629},"obj":"expanded"},{"id":"SS2_20520283_3_0","span":{"begin":631,"end":635},"obj":"abbr"},{"id":"SS1_20520283_3_1","span":{"begin":858,"end":891},"obj":"expanded"},{"id":"SS2_20520283_3_1","span":{"begin":893,"end":897},"obj":"abbr"},{"id":"SS1_20520283_5_0","span":{"begin":1357,"end":1371},"obj":"expanded"},{"id":"SS2_20520283_5_0","span":{"begin":1373,"end":1376},"obj":"abbr"}],"relations":[{"id":"AE1_20520283_3_0","pred":"abbreviatedTo","subj":"SS1_20520283_3_0","obj":"SS2_20520283_3_0"},{"id":"AE1_20520283_3_1","pred":"abbreviatedTo","subj":"SS1_20520283_3_1","obj":"SS2_20520283_3_1"},{"id":"AE1_20520283_5_0","pred":"abbreviatedTo","subj":"SS1_20520283_5_0","obj":"SS2_20520283_5_0"}],"attributes":[{"subj":"SS1_20520283_3_0","pred":"source","obj":"Allie"},{"subj":"SS2_20520283_3_0","pred":"source","obj":"Allie"},{"subj":"SS1_20520283_3_1","pred":"source","obj":"Allie"},{"subj":"SS2_20520283_3_1","pred":"source","obj":"Allie"},{"subj":"SS1_20520283_5_0","pred":"source","obj":"Allie"},{"subj":"SS2_20520283_5_0","pred":"source","obj":"Allie"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"TEST-DiseaseOrPhenotypicFeature","color":"#9a93ec","default":true},{"id":"TEST-ChemicalEntity","color":"#a5ec93"},{"id":"TEST-OrganismTaxon","color":"#ec93c0"},{"id":"Test-merged","color":"#93daec"},{"id":"Test-GeneOrGeneProduct","color":"#ece493"},{"id":"Test-merged-2","color":"#ca93ec"},{"id":"PubmedHPO","color":"#93ecb0"},{"id":"Allie","color":"#ec9693"}]}]}}