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Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-114 Sentence denotes A transcriptional signature and common gene networks link cancer with lipid metabolism and diverse human diseases.
T2 115-266 Sentence denotes Transcriptional profiling of two isogenic models of transformation identifies a gene signature linking cancer with inflammatory and metabolic diseases.
T3 267-429 Sentence denotes In accord with this common transcriptional program, many drugs used for treatment of diabetes and cardiovascular diseases inhibit transformation and tumor growth.
T4 430-538 Sentence denotes Unexpectedly, lipid metabolism genes are important for transformation and are upregulated in cancer tissues.
T5 539-676 Sentence denotes As in atherosclerosis, oxidized LDL and its receptor OLR1 activate the inflammatory pathway through NF-kappaB, leading to transformation.
T6 677-869 Sentence denotes OLR1 is important for maintaining the transformed state in developmentally diverse cancer cell lines and for tumor growth, suggesting a molecular connection between cancer and atherosclerosis.
T7 870-1029 Sentence denotes We suggest that the interplay between this common transcriptional program and cell-type-specific factors gives rise to phenotypically disparate human diseases.
T1 0-114 Sentence denotes A transcriptional signature and common gene networks link cancer with lipid metabolism and diverse human diseases.
T2 115-266 Sentence denotes Transcriptional profiling of two isogenic models of transformation identifies a gene signature linking cancer with inflammatory and metabolic diseases.
T3 267-429 Sentence denotes In accord with this common transcriptional program, many drugs used for treatment of diabetes and cardiovascular diseases inhibit transformation and tumor growth.
T4 430-538 Sentence denotes Unexpectedly, lipid metabolism genes are important for transformation and are upregulated in cancer tissues.
T5 539-676 Sentence denotes As in atherosclerosis, oxidized LDL and its receptor OLR1 activate the inflammatory pathway through NF-kappaB, leading to transformation.
T6 677-869 Sentence denotes OLR1 is important for maintaining the transformed state in developmentally diverse cancer cell lines and for tumor growth, suggesting a molecular connection between cancer and atherosclerosis.
T7 870-1029 Sentence denotes We suggest that the interplay between this common transcriptional program and cell-type-specific factors gives rise to phenotypically disparate human diseases.

LitCoin-PubTator-for-Tuning

Id Subject Object Predicate Lexical cue tao:has_database_id
3 58-64 DiseaseOrPhenotypicFeature denotes cancer MESH:D009369
4 70-75 ChemicalEntity denotes lipid MESH:D008055
5 99-104 OrganismTaxon denotes human Tax:9606
21 218-224 DiseaseOrPhenotypicFeature denotes cancer MESH:D009369
22 247-265 DiseaseOrPhenotypicFeature denotes metabolic diseases MESH:D008659
23 352-360 DiseaseOrPhenotypicFeature denotes diabetes MESH:D003920
24 365-388 DiseaseOrPhenotypicFeature denotes cardiovascular diseases MESH:D002318
25 416-421 DiseaseOrPhenotypicFeature denotes tumor MESH:D009369
26 444-449 ChemicalEntity denotes lipid MESH:D008055
27 523-529 DiseaseOrPhenotypicFeature denotes cancer MESH:D009369
28 545-560 DiseaseOrPhenotypicFeature denotes atherosclerosis MESH:D050197
29 592-596 GeneOrGeneProduct denotes OLR1 Gene:4973
30 677-681 GeneOrGeneProduct denotes OLR1 Gene:4973
31 760-766 DiseaseOrPhenotypicFeature denotes cancer MESH:D009369
32 786-791 DiseaseOrPhenotypicFeature denotes tumor MESH:D009369
33 842-848 DiseaseOrPhenotypicFeature denotes cancer MESH:D009369
34 853-868 DiseaseOrPhenotypicFeature denotes atherosclerosis MESH:D050197
35 1014-1019 OrganismTaxon denotes human Tax:9606

LitCoin-Disease-Tuning-1

Id Subject Object Predicate Lexical cue ID:
T1 58-64 DiseaseOrPhenotypicFeature denotes cancer D009369
T2 105-113 DiseaseOrPhenotypicFeature denotes diseases D004194
T3 218-224 DiseaseOrPhenotypicFeature denotes cancer D009369
T4 230-242 DiseaseOrPhenotypicFeature denotes inflammatory DISEASE
T5 247-265 DiseaseOrPhenotypicFeature denotes metabolic diseases D008659
T6 352-360 DiseaseOrPhenotypicFeature denotes diabetes DISEASE
T7 365-388 DiseaseOrPhenotypicFeature denotes cardiovascular diseases D002318
T8 416-421 DiseaseOrPhenotypicFeature denotes tumor D009369
T9 523-529 DiseaseOrPhenotypicFeature denotes cancer D009369
T10 545-560 DiseaseOrPhenotypicFeature denotes atherosclerosis D050197
T11 610-622 DiseaseOrPhenotypicFeature denotes inflammatory DISEASE
T12 760-766 DiseaseOrPhenotypicFeature denotes cancer D009369
T13 786-791 DiseaseOrPhenotypicFeature denotes tumor D009369
T14 842-848 DiseaseOrPhenotypicFeature denotes cancer D009369
T15 853-868 DiseaseOrPhenotypicFeature denotes atherosclerosis D050197
T16 1020-1028 DiseaseOrPhenotypicFeature denotes diseases D004194

LitEisuke

Id Subject Object Predicate Lexical cue #label
T1 58-64 DiseaseOrPhenotypicFeature denotes cancer D009369
T2 218-224 DiseaseOrPhenotypicFeature denotes cancer D009369
T3 247-265 DiseaseOrPhenotypicFeature denotes metabolic diseases D008659
T4 352-360 DiseaseOrPhenotypicFeature denotes diabetes DISEASE
T5 365-388 DiseaseOrPhenotypicFeature denotes cardiovascular diseases D002318
T6 416-421 DiseaseOrPhenotypicFeature denotes tumor D009369
T7 523-529 DiseaseOrPhenotypicFeature denotes cancer D009369
T8 545-560 DiseaseOrPhenotypicFeature denotes atherosclerosis D050197
T9 760-766 DiseaseOrPhenotypicFeature denotes cancer D009369
T10 786-791 DiseaseOrPhenotypicFeature denotes tumor D009369
T11 842-848 DiseaseOrPhenotypicFeature denotes cancer D009369
T12 853-868 DiseaseOrPhenotypicFeature denotes atherosclerosis D050197

DisGeNET

Id Subject Object Predicate Lexical cue
T0 592-596 gene:4973 denotes OLR1
T1 545-560 disease:C0003850 denotes atherosclerosis
T2 592-596 gene:4973 denotes OLR1
T3 545-560 disease:C0004153 denotes atherosclerosis
T4 677-681 gene:4973 denotes OLR1
T5 842-848 disease:C0006826 denotes cancer
T6 677-681 gene:4973 denotes OLR1
T7 760-766 disease:C1306459 denotes cancer
T8 677-681 gene:4973 denotes OLR1
T9 760-766 disease:C0006826 denotes cancer
T10 677-681 gene:4973 denotes OLR1
T11 842-848 disease:C1306459 denotes cancer
T12 677-681 gene:4973 denotes OLR1
T13 853-868 disease:C0003850 denotes atherosclerosis
T14 677-681 gene:4973 denotes OLR1
T15 853-868 disease:C0004153 denotes atherosclerosis
R1 T0 T1 associated_with OLR1,atherosclerosis
R2 T2 T3 associated_with OLR1,atherosclerosis
R3 T4 T5 associated_with OLR1,cancer
R4 T6 T7 associated_with OLR1,cancer
R5 T8 T9 associated_with OLR1,cancer
R6 T10 T11 associated_with OLR1,cancer
R7 T12 T13 associated_with OLR1,atherosclerosis
R8 T14 T15 associated_with OLR1,atherosclerosis

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 218-224 HP_0002664 denotes cancer
T2 416-421 HP_0002664 denotes tumor
T3 523-529 HP_0002664 denotes cancer
T4 545-560 HP_0002621 denotes atherosclerosis
T5 760-766 HP_0002664 denotes cancer
T6 786-791 HP_0002664 denotes tumor
T7 842-848 HP_0002664 denotes cancer
T8 853-868 HP_0002621 denotes atherosclerosis

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
20385360-5#0#4#gene4973 677-681 gene4973 denotes OLR1
20385360-5#176#191#diseaseC0003850 853-868 diseaseC0003850 denotes atherosclerosis
20385360-5#176#191#diseaseC0004153 853-868 diseaseC0004153 denotes atherosclerosis
0#4#gene4973176#191#diseaseC0003850 20385360-5#0#4#gene4973 20385360-5#176#191#diseaseC0003850 associated_with OLR1,atherosclerosis
0#4#gene4973176#191#diseaseC0004153 20385360-5#0#4#gene4973 20385360-5#176#191#diseaseC0004153 associated_with OLR1,atherosclerosis