PubMed:20172938 / 0-522 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/20172938","sourcedb":"PubMed","sourceid":"20172938","text":"Sevoflurane preserves the endothelial glycocalyx against ischaemia-reperfusion injury.\nBACKGROUND: Healthy vascular endothelium is coated by the glycocalyx, important in multiple endothelial functions, but destroyed by ischaemia-reperfusion. The impact of volatile anaesthetics on this fragile structure has not been investigated. We evaluated the effect of cardiac pre- and post-conditioning with sevoflurane on integrity of the endothelial glycocalyx in conjunction with coronary vascular function.\nMETHODS: Isolated gui","tracks":[{"project":"GoldHamster","denotations":[{"id":"T2","span":{"begin":0,"end":11},"obj":"36453"},{"id":"T1","span":{"begin":0,"end":11},"obj":"D000077149"},{"id":"T3","span":{"begin":0,"end":11},"obj":"CHEBI:9130"},{"id":"T4","span":{"begin":0,"end":11},"obj":"D000077149"},{"id":"T5","span":{"begin":38,"end":48},"obj":"GO:0030112"},{"id":"T6","span":{"begin":67,"end":85},"obj":"D015427"},{"id":"T7","span":{"begin":67,"end":85},"obj":"D015427"},{"id":"T8","span":{"begin":116,"end":127},"obj":"UBERON:0001986"},{"id":"T9","span":{"begin":145,"end":155},"obj":"GO:0030112"},{"id":"T10","span":{"begin":246,"end":252},"obj":"PR:Q54JW9"},{"id":"T11","span":{"begin":246,"end":252},"obj":"PR:Q642J4"},{"id":"T12","span":{"begin":265,"end":277},"obj":"CHEBI:38867"},{"id":"T15","span":{"begin":366,"end":369},"obj":"SO:0002045"},{"id":"T14","span":{"begin":366,"end":369},"obj":"PR:Q8LLD0"},{"id":"T16","span":{"begin":366,"end":369},"obj":"UBERON:0001782"},{"id":"T13","span":{"begin":366,"end":369},"obj":"GO:0003904"},{"id":"T18","span":{"begin":398,"end":409},"obj":"36453"},{"id":"T17","span":{"begin":398,"end":409},"obj":"D000077149"},{"id":"T19","span":{"begin":398,"end":409},"obj":"CHEBI:9130"},{"id":"T20","span":{"begin":398,"end":409},"obj":"D000077149"},{"id":"T21","span":{"begin":442,"end":452},"obj":"GO:0030112"}],"attributes":[{"subj":"T2","pred":"source","obj":"GoldHamster"},{"subj":"T1","pred":"source","obj":"GoldHamster"},{"subj":"T3","pred":"source","obj":"GoldHamster"},{"subj":"T4","pred":"source","obj":"GoldHamster"},{"subj":"T5","pred":"source","obj":"GoldHamster"},{"subj":"T6","pred":"source","obj":"GoldHamster"},{"subj":"T7","pred":"source","obj":"GoldHamster"},{"subj":"T8","pred":"source","obj":"GoldHamster"},{"subj":"T9","pred":"source","obj":"GoldHamster"},{"subj":"T10","pred":"source","obj":"GoldHamster"},{"subj":"T11","pred":"source","obj":"GoldHamster"},{"subj":"T12","pred":"source","obj":"GoldHamster"},{"subj":"T15","pred":"source","obj":"GoldHamster"},{"subj":"T14","pred":"source","obj":"GoldHamster"},{"subj":"T16","pred":"source","obj":"GoldHamster"},{"subj":"T13","pred":"source","obj":"GoldHamster"},{"subj":"T18","pred":"source","obj":"GoldHamster"},{"subj":"T17","pred":"source","obj":"GoldHamster"},{"subj":"T19","pred":"source","obj":"GoldHamster"},{"subj":"T20","pred":"source","obj":"GoldHamster"},{"subj":"T21","pred":"source","obj":"GoldHamster"}]},{"project":"PubMed_Structured_Abstracts","denotations":[{"id":"T1","span":{"begin":99,"end":500},"obj":"BACKGROUND"}],"attributes":[{"subj":"T1","pred":"source","obj":"PubMed_Structured_Abstracts"}]},{"project":"Goldhamster2_Cellosaurus","denotations":[{"id":"T1","span":{"begin":304,"end":307},"obj":"CVCL_6758|Undefined_cell_line_type|Cricetulus griseus"},{"id":"T2","span":{"begin":304,"end":307},"obj":"CVCL_E689|Transformed_cell_line|Homo sapiens"},{"id":"T3","span":{"begin":331,"end":333},"obj":"CVCL_5M23|Cancer_cell_line|Mesocricetus auratus"}],"attributes":[{"subj":"T1","pred":"source","obj":"Goldhamster2_Cellosaurus"},{"subj":"T2","pred":"source","obj":"Goldhamster2_Cellosaurus"},{"subj":"T3","pred":"source","obj":"Goldhamster2_Cellosaurus"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"GoldHamster","color":"#b193ec","default":true},{"id":"PubMed_Structured_Abstracts","color":"#93ec97"},{"id":"Goldhamster2_Cellosaurus","color":"#ec93a8"}]}]}}