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PubMed:1990263 JSONTXT

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jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 0-22 protein denotes Nuclear factor kappa B
T2 64-77 cell_type denotes T lymphocytes
T3 96-109 cell_type denotes T lymphocytes
T4 200-218 RNA denotes proenkephalin mRNA
T5 366-368 DNA denotes B2
T6 394-410 DNA denotes kappa B sequence
T7 448-468 protein denotes transcription factor
T8 469-496 protein denotes nuclear factor (NF)-kappa B
T9 512-525 cell_type denotes T lymphocytes
T10 537-547 protein denotes NF-kappa B
T11 577-579 DNA denotes B2
T12 621-643 DNA denotes proenkephalin promoter
T13 662-664 DNA denotes B2
T14 724-733 protein denotes homodimer
T15 739-743 protein denotes p50s
T16 752-771 protein denotes DNA-binding subunit
T17 775-785 protein denotes NF-kappa B
T18 796-798 DNA denotes B2
T19 853-867 protein denotes heterotetramer
T20 873-877 protein denotes p65s
T21 887-891 protein denotes p50s
T22 973-995 DNA denotes proenkephalin promoter
T23 1011-1021 protein denotes NF-kappa B
T24 1035-1045 protein denotes NF-kappa B
T25 1107-1109 DNA denotes B2
T26 1147-1169 protein denotes T-cell-specific factor
T27 1192-1202 protein denotes NF-kappa B

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-78 Sentence denotes Nuclear factor kappa B activates proenkephalin transcription in T lymphocytes.
S2 79-232 Sentence denotes Upon activation, T lymphocytes accumulate high levels of the neuropeptide enkephalin which correlate with high levels of proenkephalin mRNA in the cells.
S3 233-298 Sentence denotes Here we investigated the transcriptional basis for these changes.
S4 299-497 Sentence denotes The proenkephalin promoter contains a sequence GGGGACGTCCCC, named B2, which is similar to the kappa B sequence GGGGACTTTCC, the binding site of the transcription factor nuclear factor (NF)-kappa B.
S5 498-644 Sentence denotes Activation of T lymphocytes induces an NF-kappa B-like binding activity to the B2 site, concomitant with activation of the proenkephalin promoter.
S6 645-710 Sentence denotes Mutations at the B2 site abolish this transcriptional activation.
S7 711-912 Sentence denotes The purified homodimer (two p50s) of the DNA-binding subunit of NF-kappa B binds the B2 site of proenkephalin relatively better than does the heterotetramer (two p65s plus two p50s) form of the factor.
S8 913-1022 Sentence denotes Thus, it appears that the T-cell-specific activation of the proenkephalin promoter is mediated by NF-kappa B.
S9 1023-1224 Sentence denotes However, as NF-kappa B is ubiquitous and the transcriptional activation through the B2 site is T cell specific, yet another T-cell-specific factor which synergizes with NF-kappa B should be considered.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 0-22 NP denotes Nuclear factor kappa B
C2 64-77 NP denotes T lymphocytes
C3 96-109 NP denotes T lymphocytes
C4 121-163 NP denotes high levels of the neuropeptide enkephalin
C5 164-169 NP denotes which
C6 222-231 NP denotes the cells
C7 299-325 NP denotes The proenkephalin promoter
C8 335-358 NP denotes a sequence GGGGACGTCCCC
C9 366-368 NP denotes B2
C10 370-375 NP denotes which
C11 390-422 NP denotes the kappa B sequence GGGGACTTTCC
C13 469-496 NP denotes nuclear factor (NF)-kappa B
C12 424-496 NP denotes the binding site of the transcription factor nuclear factor (NF)-kappa B
C15 512-525 NP denotes T lymphocytes
C14 498-525 NP denotes Activation of T lymphocytes
C16 573-584 NP denotes the B2 site
C17 617-643 NP denotes the proenkephalin promoter
C18 658-669 NP denotes the B2 site
C19 678-709 NP denotes this transcriptional activation
C20 775-785 NP denotes NF-kappa B
C21 792-803 NP denotes the B2 site
C22 901-911 NP denotes the factor
C23 969-995 NP denotes the proenkephalin promoter
C24 1011-1021 NP denotes NF-kappa B
C25 1035-1045 NP denotes NF-kappa B
C26 1103-1114 NP denotes the B2 site
C27 1192-1202 NP denotes NF-kappa B
R1 C3 C2 coref-ident T lymphocytes,T lymphocytes
R2 C5 C4 coref-relat which,high levels of the neuropeptide enkephalin
R3 C6 C3 coref-other the cells,T lymphocytes
R4 C9 C8 coref-ident B2,a sequence GGGGACGTCCCC
R5 C10 C9 coref-relat which,B2
R6 C13 C1 coref-ident nuclear factor (NF)-kappa B,Nuclear factor kappa B
R7 C12 C11 coref-other the binding site of the transcription factor nuclear factor (NF)-kappa B,the kappa B sequence GGGGACTTTCC
R8 C15 C3 coref-ident T lymphocytes,T lymphocytes
R9 C17 C7 coref-ident the proenkephalin promoter,The proenkephalin promoter
R10 C18 C16 coref-ident the B2 site,the B2 site
R11 C19 C14 coref-other this transcriptional activation,Activation of T lymphocytes
R12 C20 C13 coref-ident NF-kappa B,nuclear factor (NF)-kappa B
R13 C21 C16 coref-ident the B2 site,the B2 site
R14 C22 C20 coref-ident the factor,NF-kappa B
R15 C23 C17 coref-ident the proenkephalin promoter,the proenkephalin promoter
R16 C24 C20 coref-ident NF-kappa B,NF-kappa B
R17 C25 C24 coref-ident NF-kappa B,NF-kappa B
R18 C26 C21 coref-ident the B2 site,the B2 site
R19 C27 C25 coref-ident NF-kappa B,NF-kappa B

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 0-22 protein_molecule denotes Nuclear factor kappa B
T2 33-46 peptide denotes proenkephalin
T3 47-60 other_name denotes transcription
T4 64-77 cell_type denotes T lymphocytes
T5 96-109 cell_type denotes T lymphocytes
T6 140-163 peptide denotes neuropeptide enkephalin
T7 200-213 peptide denotes proenkephalin
T8 258-279 other_name denotes transcriptional basis
T9 303-316 peptide denotes proenkephalin
T10 346-358 polynucleotide denotes GGGGACGTCCCC
T11 366-368 DNA_domain_or_region denotes B2
T12 394-410 DNA_domain_or_region denotes kappa B sequence
T13 411-422 polynucleotide denotes GGGGACTTTCC
T14 448-461 other_name denotes transcription
T15 469-496 protein_molecule denotes nuclear factor (NF)-kappa B
T16 512-525 cell_type denotes T lymphocytes
T17 537-547 protein_molecule denotes NF-kappa B
T18 577-579 DNA_domain_or_region denotes B2
T19 621-634 peptide denotes proenkephalin
T20 662-664 DNA_domain_or_region denotes B2
T21 683-709 other_name denotes transcriptional activation
T22 724-733 protein_complex denotes homodimer
T23 739-743 protein_subunit denotes p50s
T24 752-771 protein_domain_or_region denotes DNA-binding subunit
T25 775-785 protein_molecule denotes NF-kappa B
T26 796-798 DNA_domain_or_region denotes B2
T27 807-820 peptide denotes proenkephalin
T28 853-867 protein_complex denotes heterotetramer
T29 873-877 protein_subunit denotes p65s
T30 887-891 protein_subunit denotes p50s
T31 939-965 other_name denotes T-cell-specific activation
T32 973-986 peptide denotes proenkephalin
T33 1011-1021 protein_molecule denotes NF-kappa B
T34 1035-1045 protein_molecule denotes NF-kappa B
T35 1068-1094 other_name denotes transcriptional activation
T36 1107-1109 DNA_domain_or_region denotes B2
T37 1118-1133 other_name denotes T cell specific
T38 1147-1169 protein_molecule denotes T-cell-specific factor
T39 1192-1202 protein_molecule denotes NF-kappa B