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PubMed:1980125 JSONTXT

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DisGeNET

Id Subject Object Predicate Lexical cue
T0 105-132 gene:3562 denotes hematopoietic growth factor
T1 78-92 disease:C0006142 denotes breast cancers
R1 T0 T1 associated_with hematopoietic growth factor,breast cancers

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 105-132 protein denotes hematopoietic growth factor
T2 144-155 cell_type denotes tumor cells
T3 418-440 DNA denotes c-erbB2 gene sequences
T4 479-484 DNA denotes Int-2
T5 512-517 DNA denotes c-myc
T6 647-654 DNA denotes c-erbB2
T7 722-743 protein denotes progesterone receptor
T8 745-747 protein denotes PR
T9 1031-1038 DNA denotes c-erbB2
T10 1182-1190 DNA denotes oncogene
T11 1462-1470 protein denotes cytokine

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
1980125-0#105#132#gene3562 105-132 gene3562 denotes hematopoietic growth factor
1980125-0#78#92#diseaseC0006142 78-92 diseaseC0006142 denotes breast cancers
105#132#gene356278#92#diseaseC0006142 1980125-0#105#132#gene3562 1980125-0#78#92#diseaseC0006142 associated_with hematopoietic growth factor,breast cancers

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-156 Sentence denotes Oncogene amplification correlates with dense lymphocyte infiltration in human breast cancers: a role for hematopoietic growth factor release by tumor cells?
S2 157-266 Sentence denotes One hundred six primary breast cancer samples were analysed for c-erbB2, int-2, and c-myc gene amplification.
S3 267-326 Sentence denotes Surgically confirmed nodal involvement was observed in 42%.
S4 327-407 Sentence denotes Level of gene amplification was studied by Southern and/or slot blot techniques.
S5 408-478 Sentence denotes Amplified c-erbB2 gene sequences were present in 21.5% of all samples.
S6 479-541 Sentence denotes Int-2 was amplified in 13.1% and c-myc was amplified in 10.3%.
S7 542-771 Sentence denotes In a non-parametric test (Kruskal-Wallis) a strong negative association was found between high levels of c-erbB2 amplification and absence of estrogen receptor (ER) (P = .0009) or progesterone receptor (PR) (P = .011) expression.
S8 772-957 Sentence denotes No correlations were found between all or high levels of amplification of each oncogene separately or combined with T, N, grade, multifocality of tumor, or associated carcinoma in situ.
S9 958-1105 Sentence denotes There was a trend approaching statistical significance for patients with c-erbB2 amplifications to have positive lymph nodes at surgery (P = 0.09).
S10 1106-1262 Sentence denotes A somewhat surprising finding however was a very strong association between oncogene amplification and dense lymphocyte infiltration of the tumor (P = .05).
S11 1263-1430 Sentence denotes This correlation is even stronger when only high levels of amplification are considered, either for each oncogene separately (P = .0048) or in combination (P = .0007).
S12 1431-1516 Sentence denotes We propose that malignant cell cytokine production may help explain this observation.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 0-22 NP denotes Oncogene amplification
C2 157-202 NP denotes One hundred six primary breast cancer samples
C3 230-235 NP denotes int-2
C4 336-354 NP denotes gene amplification
C5 466-477 NP denotes all samples
C6 479-484 NP denotes Int-2
C7 647-668 NP denotes c-erbB2 amplification
C8 1031-1053 NP denotes c-erbB2 amplifications
C10 1182-1204 NP denotes oncogene amplification
C9 1148-1261 NP denotes a very strong association between oncogene amplification and dense lymphocyte infiltration of the tumor (P = .05)
C11 1263-1279 NP denotes This correlation
R1 C4 C1 coref-ident gene amplification,Oncogene amplification
R2 C5 C2 coref-ident all samples,One hundred six primary breast cancer samples
R3 C6 C3 coref-ident Int-2,int-2
R4 C8 C7 coref-ident c-erbB2 amplifications,c-erbB2 amplification
R5 C10 C4 coref-ident oncogene amplification,gene amplification
R6 C11 C9 coref-ident This correlation,a very strong association between oncogene amplification and dense lymphocyte infiltration of the tumor (P = .05)

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 0-22 other_name denotes Oncogene amplification
T2 45-68 other_name denotes lymphocyte infiltration
T3 72-92 other_name denotes human breast cancers
T4 105-132 protein_family_or_group denotes hematopoietic growth factor
T5 144-155 cell_type denotes tumor cells
T6 173-202 other_name denotes primary breast cancer samples
T7 288-305 other_name denotes nodal involvement
T8 336-354 other_name denotes gene amplification
T9 370-378 other_name denotes Southern
T10 386-406 other_name denotes slot blot techniques
T11 418-440 DNA_molecule denotes c-erbB2 gene sequences
T12 479-484 DNA_domain_or_region denotes Int-2
T13 512-517 DNA_domain_or_region denotes c-myc
T14 547-566 other_name denotes non-parametric test
T15 647-654 DNA_domain_or_region denotes c-erbB2
T16 722-743 protein_family_or_group denotes progesterone receptor
T17 745-747 protein_family_or_group denotes PR
T18 901-923 other_name denotes multifocality of tumor
T19 928-948 other_name denotes associated carcinoma
T20 1017-1025 multi_cell denotes patients
T21 1031-1038 DNA_domain_or_region denotes c-erbB2
T22 1062-1070 tissue denotes positive
T23 1071-1082 tissue denotes lymph nodes
T24 1182-1190 DNA_family_or_group denotes oncogene
T25 1215-1238 other_name denotes lymphocyte infiltration
T26 1246-1251 tissue denotes tumor
T27 1447-1461 other_name denotes malignant cell
T28 1462-1470 protein_family_or_group denotes cytokine