PubMed:19789368 / 723-1050 JSONTXT

{"project":"LitCoin-sentences","denotations":[{"id":"T7","span":{"begin":0,"end":327},"obj":"Sentence"}],"text":"We analyzed for PIK3CA and KRAS mutations and LINE-1 methylation by Pyrosequencing, microsatellite instability (MSI), and DNA methylation (epigenetic changes) in eight CpG island methylator phenotype (CIMP)-specific promoters [CACNA1G, CDKN2A (p16), CRABP1, IGF2, MLH1, NEUROG1, RUNX3, and SOCS1] by MethyLight (real-time PCR)."}

{"project":"LitCoin-entities","denotations":[{"id":"6538","span":{"begin":16,"end":22},"obj":"GeneOrGeneProduct"},{"id":"6539","span":{"begin":27,"end":31},"obj":"GeneOrGeneProduct"},{"id":"6540","span":{"begin":227,"end":234},"obj":"GeneOrGeneProduct"},{"id":"6541","span":{"begin":236,"end":242},"obj":"GeneOrGeneProduct"},{"id":"6542","span":{"begin":244,"end":247},"obj":"GeneOrGeneProduct"},{"id":"6543","span":{"begin":250,"end":256},"obj":"GeneOrGeneProduct"},{"id":"6544","span":{"begin":258,"end":262},"obj":"GeneOrGeneProduct"},{"id":"6545","span":{"begin":264,"end":268},"obj":"GeneOrGeneProduct"},{"id":"6546","span":{"begin":270,"end":277},"obj":"GeneOrGeneProduct"},{"id":"6547","span":{"begin":279,"end":284},"obj":"GeneOrGeneProduct"},{"id":"6548","span":{"begin":290,"end":295},"obj":"GeneOrGeneProduct"}],"attributes":[{"id":"A23","pred":"db_id","subj":"6538","obj":"NCBIGene:5290"},{"id":"A24","pred":"db_id","subj":"6539","obj":"NCBIGene:3845"},{"id":"A25","pred":"db_id","subj":"6540","obj":"NCBIGene:8913"},{"id":"A26","pred":"db_id","subj":"6541","obj":"NCBIGene:1029"},{"id":"A27","pred":"db_id","subj":"6542","obj":"NCBIGene:1029"},{"id":"A28","pred":"db_id","subj":"6543","obj":"NCBIGene:1381"},{"id":"A29","pred":"db_id","subj":"6544","obj":"NCBIGene:3481"},{"id":"A30","pred":"db_id","subj":"6545","obj":"NCBIGene:4292"},{"id":"A31","pred":"db_id","subj":"6546","obj":"NCBIGene:4762"},{"id":"A32","pred":"db_id","subj":"6547","obj":"NCBIGene:864"},{"id":"A33","pred":"db_id","subj":"6548","obj":"NCBIGene:8651"}],"namespaces":[{"prefix":"_base","uri":"https://w3id.org/biolink/vocab/"},{"prefix":"MESH","uri":"http://id.nlm.nih.gov/mesh/"},{"prefix":"NCBITaxon","uri":"https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id="},{"prefix":"NCBIGene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"OMIM","uri":"https://www.omim.org/entry/"},{"prefix":"DBSNP","uri":"https://www.ncbi.nlm.nih.gov/snp/"}],"text":"We analyzed for PIK3CA and KRAS mutations and LINE-1 methylation by Pyrosequencing, microsatellite instability (MSI), and DNA methylation (epigenetic changes) in eight CpG island methylator phenotype (CIMP)-specific promoters [CACNA1G, CDKN2A (p16), CRABP1, IGF2, MLH1, NEUROG1, RUNX3, and SOCS1] by MethyLight (real-time PCR)."}

{"project":"LitCoin-GeneOrGeneProduct-v0","denotations":[{"id":"T20","span":{"begin":16,"end":22},"obj":"GeneOrGeneProduct"},{"id":"T21","span":{"begin":27,"end":31},"obj":"GeneOrGeneProduct"},{"id":"T22","span":{"begin":32,"end":41},"obj":"GeneOrGeneProduct"},{"id":"T23","span":{"begin":46,"end":50},"obj":"GeneOrGeneProduct"},{"id":"T24","span":{"begin":122,"end":137},"obj":"GeneOrGeneProduct"},{"id":"T25","span":{"begin":227,"end":234},"obj":"GeneOrGeneProduct"},{"id":"T26","span":{"begin":236,"end":242},"obj":"GeneOrGeneProduct"},{"id":"T27","span":{"begin":250,"end":256},"obj":"GeneOrGeneProduct"},{"id":"T28","span":{"begin":258,"end":262},"obj":"GeneOrGeneProduct"},{"id":"T29","span":{"begin":264,"end":268},"obj":"GeneOrGeneProduct"},{"id":"T30","span":{"begin":270,"end":277},"obj":"GeneOrGeneProduct"},{"id":"T31","span":{"begin":279,"end":284},"obj":"GeneOrGeneProduct"},{"id":"T32","span":{"begin":290,"end":295},"obj":"GeneOrGeneProduct"},{"id":"T33","span":{"begin":312,"end":321},"obj":"GeneOrGeneProduct"}],"text":"We analyzed for PIK3CA and KRAS mutations and LINE-1 methylation by Pyrosequencing, microsatellite instability (MSI), and DNA methylation (epigenetic changes) in eight CpG island methylator phenotype (CIMP)-specific promoters [CACNA1G, CDKN2A (p16), CRABP1, IGF2, MLH1, NEUROG1, RUNX3, and SOCS1] by MethyLight (real-time PCR)."}

{"project":"LitCoin-GeneOrGeneProduct-v2","denotations":[{"id":"T18","span":{"begin":16,"end":22},"obj":"GeneOrGeneProduct"},{"id":"T19","span":{"begin":27,"end":31},"obj":"GeneOrGeneProduct"},{"id":"T20","span":{"begin":122,"end":137},"obj":"GeneOrGeneProduct"},{"id":"T21","span":{"begin":227,"end":234},"obj":"GeneOrGeneProduct"},{"id":"T22","span":{"begin":236,"end":242},"obj":"GeneOrGeneProduct"},{"id":"T23","span":{"begin":250,"end":256},"obj":"GeneOrGeneProduct"},{"id":"T24","span":{"begin":258,"end":262},"obj":"GeneOrGeneProduct"},{"id":"T25","span":{"begin":264,"end":268},"obj":"GeneOrGeneProduct"},{"id":"T26","span":{"begin":270,"end":277},"obj":"GeneOrGeneProduct"},{"id":"T27","span":{"begin":279,"end":284},"obj":"GeneOrGeneProduct"},{"id":"T28","span":{"begin":290,"end":295},"obj":"GeneOrGeneProduct"},{"id":"T29","span":{"begin":312,"end":321},"obj":"GeneOrGeneProduct"}],"text":"We analyzed for PIK3CA and KRAS mutations and LINE-1 methylation by Pyrosequencing, microsatellite instability (MSI), and DNA methylation (epigenetic changes) in eight CpG island methylator phenotype (CIMP)-specific promoters [CACNA1G, CDKN2A (p16), CRABP1, IGF2, MLH1, NEUROG1, RUNX3, and SOCS1] by MethyLight (real-time PCR)."}

{"project":"LitCoin-Disease-MeSH","denotations":[{"id":"T6","span":{"begin":84,"end":110},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T7","span":{"begin":112,"end":115},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A6","pred":"originalLabel","subj":"T6","obj":"D053842"},{"id":"A7","pred":"originalLabel","subj":"T7","obj":"D053842"}],"text":"We analyzed for PIK3CA and KRAS mutations and LINE-1 methylation by Pyrosequencing, microsatellite instability (MSI), and DNA methylation (epigenetic changes) in eight CpG island methylator phenotype (CIMP)-specific promoters [CACNA1G, CDKN2A (p16), CRABP1, IGF2, MLH1, NEUROG1, RUNX3, and SOCS1] by MethyLight (real-time PCR)."}

{"project":"LitCoin-GeneOrGeneProduct-v3","denotations":[{"id":"T17","span":{"begin":16,"end":22},"obj":"GeneOrGeneProduct"},{"id":"T18","span":{"begin":27,"end":31},"obj":"GeneOrGeneProduct"},{"id":"T19","span":{"begin":227,"end":234},"obj":"GeneOrGeneProduct"},{"id":"T20","span":{"begin":236,"end":242},"obj":"GeneOrGeneProduct"},{"id":"T21","span":{"begin":250,"end":256},"obj":"GeneOrGeneProduct"},{"id":"T22","span":{"begin":258,"end":262},"obj":"GeneOrGeneProduct"},{"id":"T23","span":{"begin":264,"end":268},"obj":"GeneOrGeneProduct"},{"id":"T24","span":{"begin":270,"end":277},"obj":"GeneOrGeneProduct"},{"id":"T25","span":{"begin":279,"end":284},"obj":"GeneOrGeneProduct"},{"id":"T26","span":{"begin":290,"end":295},"obj":"GeneOrGeneProduct"}],"text":"We analyzed for PIK3CA and KRAS mutations and LINE-1 methylation by Pyrosequencing, microsatellite instability (MSI), and DNA methylation (epigenetic changes) in eight CpG island methylator phenotype (CIMP)-specific promoters [CACNA1G, CDKN2A (p16), CRABP1, IGF2, MLH1, NEUROG1, RUNX3, and SOCS1] by MethyLight (real-time PCR)."}

{"project":"LitCoin-MeSH-Disease-2","denotations":[{"id":"T7","span":{"begin":84,"end":110},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T8","span":{"begin":112,"end":115},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A7","pred":"ID:","subj":"T7","obj":"D053842"},{"id":"A8","pred":"ID:","subj":"T8","obj":"D053842"}],"text":"We analyzed for PIK3CA and KRAS mutations and LINE-1 methylation by Pyrosequencing, microsatellite instability (MSI), and DNA methylation (epigenetic changes) in eight CpG island methylator phenotype (CIMP)-specific promoters [CACNA1G, CDKN2A (p16), CRABP1, IGF2, MLH1, NEUROG1, RUNX3, and SOCS1] by MethyLight (real-time PCR)."}

{"project":"LitCoin-Chemical-MeSH-CHEBI","denotations":[{"id":"T7","span":{"begin":168,"end":171},"obj":"ChemicalEntity"}],"attributes":[{"id":"A7","pred":"ID:","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_165823"}],"text":"We analyzed for PIK3CA and KRAS mutations and LINE-1 methylation by Pyrosequencing, microsatellite instability (MSI), and DNA methylation (epigenetic changes) in eight CpG island methylator phenotype (CIMP)-specific promoters [CACNA1G, CDKN2A (p16), CRABP1, IGF2, MLH1, NEUROG1, RUNX3, and SOCS1] by MethyLight (real-time PCR)."}

{"project":"LitCoin-training-merged","denotations":[{"id":"T7","span":{"begin":168,"end":171},"obj":"ChemicalEntity"},{"id":"T26","span":{"begin":290,"end":295},"obj":"GeneOrGeneProduct"},{"id":"T25","span":{"begin":279,"end":284},"obj":"GeneOrGeneProduct"},{"id":"T24","span":{"begin":270,"end":277},"obj":"GeneOrGeneProduct"},{"id":"T23","span":{"begin":264,"end":268},"obj":"GeneOrGeneProduct"},{"id":"T22","span":{"begin":258,"end":262},"obj":"GeneOrGeneProduct"},{"id":"T21","span":{"begin":250,"end":256},"obj":"GeneOrGeneProduct"},{"id":"T20","span":{"begin":236,"end":242},"obj":"GeneOrGeneProduct"},{"id":"T19","span":{"begin":227,"end":234},"obj":"GeneOrGeneProduct"},{"id":"T18","span":{"begin":27,"end":31},"obj":"GeneOrGeneProduct"},{"id":"T17","span":{"begin":16,"end":22},"obj":"GeneOrGeneProduct"}],"attributes":[{"id":"A7","pred":"ID:","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_165823"}],"text":"We analyzed for PIK3CA and KRAS mutations and LINE-1 methylation by Pyrosequencing, microsatellite instability (MSI), and DNA methylation (epigenetic changes) in eight CpG island methylator phenotype (CIMP)-specific promoters [CACNA1G, CDKN2A (p16), CRABP1, IGF2, MLH1, NEUROG1, RUNX3, and SOCS1] by MethyLight (real-time PCR)."}