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[Modeling of interaction between Yersinia pestis and Tetrahymena pyriformis in experimental ecosystems].
Modeling of interaction Yersinia pestis-Tetrahymena pyriformis in artificial soil ecosystem (ASE) containing soil of burrows of main carrier from Gorno-Altayski natural plague reservoir, as well as in physiological solution (PS) and in Hottinger broth (HB). Optimal proportion of bacterial and protozoa cells was possible to obtain and depended from virulence of Y. pestis and environmental conditions. In ASE at 18-22 degrees C association was the most stable under the microbial burden of 100 microbial cells (m.c.) per infusorian. Resistance of plague agent to phagocytosis by T. pyriformis was determined by strain's virulence. Avirulent strain Y. pestis [cyrillic letter: see text]-2377 was rapidly eliminated by protozoan in HB, PS and in ASE under the burden of 10 m.c per infusorian. Y. pestis [cyrillic letter: see text]-3443 with selective virulence compared with [cyrillic letter: see text]-2377 preserved in association longer in any tested medium. Highly virulent Y. pestis [cyrillic letter: see text]-3448 was the most resistant to phagocytosis by T. pyriformis.
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